J. Dahm-Daphi

发表

p53: Biology and Role for Cellular Radiosensitivity

J. Dahm-Daphi, 2000, Strahlentherapie und Onkologie.

Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53.

S. Powell, J. Dahm-Daphi, H. Willers, 2001, Carcinogenesis.

Heat effects on DNA repair after ionising radiation: hyperthermia commonly increases the number of non-repaired double-strand breaks and structural rearrangements.

J. Dahm-Daphi, R. El-Awady, E. Dikomey, 2001, Nucleic acids research.

Comparison of biological effects of DNA damage induced by ionizing radiation and hydrogen peroxide in CHO cells.

J. Dahm-Daphi, W. Alberti, C. Sass, 2000, International journal of radiation biology.

Heat effects on the repair of DNA double-strand breaks in CHO cells.

J. Dahm-Daphi, E. Dikomey, I. Brammer, 1997, International journal of radiation biology.

The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair.

M. Krause, M. Baumann, J. Dahm-Daphi, 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Establishment of a Transformation Coupled in vitro End Joining Assay to Estimate Radiosensitivity in Tumor Cells

J. Dahm-Daphi, K. Rothkamm, E. Dikomey, 2020, Frontiers in Oncology.

Radiosensitization of tumour cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis.

J. Dahm-Daphi, G. Mayr, E. Dikomey, 2007, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Comparison of Short-Course versus Long-Course Whole-Brain Radiotherapy in the Treatment of Brain Metastases

L. Stalpers, D. Rades, J. Dahm-Daphi, 2008, Strahlentherapie und Onkologie.

Repair of radiation damage to DNA

S. Powell, J. Dahm-Daphi, H. Willers, 2004, British Journal of Cancer.

Residual γH2AX foci predict local tumour control after radiotherapy.

M. Krause, M. Baumann, H. Thames, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

ATR-p53 Restricts Homologous Recombination in Response to Replicative Stress but Does Not Limit DNA Interstrand Crosslink Repair in Lung Cancer Cells

S. Powell, J. Dahm-Daphi, H. Willers, 2011, PloS one.

Separation of DNA fragments induced by ionizing irradiation using a graded-field gel electrophoresis.

J. Dahm-Daphi, E. Dikomey, 1995, International journal of radiation biology.

Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells

J. Dahm-Daphi, A. Böhnke, R. El-Awady, 2004, International journal of radiation biology.

Sensitive nonradioactive detection of UV-induced cyclobutane pyrimidine dimers in intact mammalian cells.

A. Hartwig, J. Dahm-Daphi, D. Beyersmann, 1995, Mutation research.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Bernhard Kuster, Matthias Mann, Moshe Oren, 2011, Molecular cell.

Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair.

C. Bokemeyer, J. Dahm-Daphi, J. Thomale, 2012, Cancer letters.

Distinct Mechanisms of Nonhomologous End Joining in the Repair of Site-Directed Chromosomal Breaks with Noncomplementary and Complementary Ends

S. Powell, J. Dahm-Daphi, H. Willers, 2006, Radiation research.

Targeting DNA double-strand break repair: is it the right way for sensitizing cells to 5-fluorouracil?

J. Dahm-Daphi, E. Saleh, R. El-Awady, 2010, Anti-cancer drugs.

Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines.

J. Dahm-Daphi, B. Kaina, E. Dikomey, 2009, International journal of radiation biology.

Comparison between the alkaline unwinding technique and neutral filter elution using CHO, V79 and EAT cells.

J. Dahm-Daphi, M. Flentje, E. Dikomey, 1995, International journal of radiation biology.

In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.

J. Dahm-Daphi, E. Dikomey, M. Kriegs, 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Radiosensitivity of human tumour cells is correlated with the induction but not with the repair of DNA double-strand breaks

J. Dahm-Daphi, R. El-Awady, E. Dikomey, 2003, British Journal of Cancer.

Hierarchy of Nonhomologous Endjoining, Single-strand Annealing and Gene Conversion at Site-directed DNA Double-strand Breaks

J. Dahm-Daphi, H. Willers, F. Haag, 2008 .

Short-course radiotherapy is not optimal for spinal cord compression due to myeloma.

L. Stalpers, D. Rades, P. Hoskin, 2006, International journal of radiation oncology, biology, physics.

Indicators of late normal tissue response after radiotherapy for head and neck cancer: fibroblasts, lymphocytes, genetics, DNA repair, and chromosome aberrations.

J. Dahm-Daphi, E. Dikomey, B. Röper, 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

The Influence of Cadmium on the Repair of DNA Double-Strand Breaks

J. Dahm-Daphi, E. Dikomey, 2014 .

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

J. Dahm-Daphi, W. Mansour, Wael Y. Mansour, 2010, Nucleic acids research.

Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.

T. Dörk, N. Bogdanova, M. Baumann, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks.

J. Settleman, C. Benes, M. Krause, 2011, Cancer research.

Therapeutics , Targets , and Chemical Biology EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells SustainingDNADouble-Strand Breaks

J. Settleman, C. Benes, M. Krause, 2011 .

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase

J. Dahm-Daphi, G. Rohaly, E. Dikomey, 2012, Nucleic acids research.

Prädiktion von Normal- und Tumorreaktion nach Strahlentherapie

J. Dahm-Daphi, L. Distel, E. Dikomey, 2012, Strahlentherapie und Onkologie.

The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining.

J. Dahm-Daphi, E. Dikomey, C. Petersen, 2013, DNA repair.

Rejoining of DNA double-strand breaks in X-irradiated CHO cells studied by constant- and graded-field gel electrophoresis.

J. Dahm-Daphi, E. Dikomey, 1996, International journal of radiation biology.

Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks

J. Dahm-Daphi, H. Willers, R. El-Awady, 2008, Nucleic acids research.

DNA Repair and Cell Cycle Regulation After Ionizing Irradiation

J. Dahm-Daphi, G. Iliakis, E. Dikomey, 2009 .

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks

J. Dahm-Daphi, H. Willers, F. Haag, 2008, Nucleic acids research.

Relationship between non-reparable DNA strand breaks and cell survival studied in X-irradiated CHO, CHO K1, xrs1 and xrs5 cells.

J. Dahm-Daphi, E. Dikomey, C. Pyttlik, 1994, International journal of radiation biology.

Recombination and Radiation-Induced Cancer. Mechanisms and Genetic Testing

J. Dahm-Daphi, P. Hubbe, 2004 .

Non-reparable DNA strand breaks and cell killing studied in CHO cells after X-irradiation at different passage numbers.

J. Dahm-Daphi, E. Dikomey, 1994, International journal of radiation biology.

Reparable and non-reparable DNA strand breaks induced by X-irradiation in CHO K1 cells and the radiosensitive mutants xrs1 and xrs5.

P. Jeggo, J. Dahm-Daphi, E. Dikomey, 1993, International journal of radiation biology.

p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation

J. Dahm-Daphi, G. Rohaly, E. Dikomey, 2013, Oncogene.

No correlation between radiosensitivity or double-strand break repair capacity of normal fibroblasts and acute normal tissue reaction after radiotherapy of breast cancer patients

J. Dahm-Daphi, E. Saleh, R. El-Awady, 2005, International journal of radiation biology.

Detection of Impaired Homologous Recombination Repair in NSCLC Cells and Tissues

L. Sequist, C. Benes, J. Whetstine, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks.

J. Dahm-Daphi, M. Kriegs, S. Köcher, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Inhibition of PARP1‐dependent end‐joining contributes to Olaparib‐mediated radiosensitization in tumor cells

J. Dahm-Daphi, K. Cornils, E. Dikomey, 2014, Molecular oncology.

Distinct roles of XRCC 4 and Ku 80 in non-homologous end-joining of endonuclease-and ionizing radiation-induced DNA double-strand breaks

J. Dahm-Daphi, H. Willers, R. El-Awady, 2008 .

Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53

S. Powell, J. Dahm-Daphi, H. Willers, 2005, Oncogene.

Is Short-Course Radiotherapy with High Doses per Fraction the Appropriate Regimen for Metastatic Spinal Cord Compression in Colorectal Cancer Patients?

L. Stalpers, D. Rades, P. Hoskin, 2006, Strahlentherapie und Onkologie.

FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase poisons.

J. Dahm-Daphi, L. Kachnic, H. Willers, 2011, Cancer letters.

Carbon ion radiotherapy of human lung cancer attenuates HIF‐1 signaling and acts with considerably enhanced therapeutic efficiency

W. Seeger, J. Dahm-Daphi, C. Fournier, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining.

J. Dahm-Daphi, E. Dikomey, M. Kriegs, 2010, DNA repair.

Reply: Tumour and normal cells differ in the induction and repair of DNA double-strand breaks

J. Dahm-Daphi, R. El-Awady, E. Dikomey, 2004, British Journal of Cancer.

Comparative studies of induction and repair of DNA double-strand breaks in X-irradiated alveolar macrophages and resting peripheral blood lymphocytes using constant-field gel electrophoresis.

J. Dahm-Daphi, E. Dikomey, A. Zander, 1995, International journal of radiation biology.

Loss of wild-type p53 function is responsible for upregulated homologous recombination in immortal rodent fibroblasts.

J. Dahm-Daphi, H. Willers, E. McCarthy, 2000, International journal of radiation biology.

In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.

J. Dahm-Daphi, E. Dikomey, M. Kriegs, 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Originalarbeit p 53 : Biology and Role for Cellular Radiosensitivity

J. Dahm-Daphi, 2022 .