I. de Waziers

发表

p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.

P. Beaune, P. Laurent-Puig, D. Brasnu, 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Identification of a 16-Nucleotide Sequence That Mediates Post-transcriptional Regulation of Rat CYP2E1 by Insulin*

P. Beaune, R. Barouki, I. de Waziers, 2002, The Journal of Biological Chemistry.

Rat liver epithelial cells express functional cytochrome P450 2E1.

L. Corcos, A. Guillouzo, I. de Waziers, 1996, Carcinogenesis.

Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility.

M. Loriot, P. Beaune, D. Hémon, 2002, Carcinogenesis.

Xenobiotic-Metabolizing Cytochromes P450 in Human White Adipose Tissue: Expression and Induction

P. Beaune, I. de Waziers, L. Pénicaud, 2010, Drug Metabolism and Disposition.

Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolizing enzyme systems.

P. Beaune, I. de Waziers, F. Janot, 1992, Cancer research.

Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors.

P. Beaune, I. de Waziers, I. Amara, 2014, Biochimie.

Important Role of CYP2J2 in Protein Kinase Inhibitor Degradation: A Possible Role in Intratumor Drug Disposition and Resistance

P. Beaune, M. Montemurro, I. de Waziers, 2014, PloS one.

Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR

M. Loriot, P. Beaune, I. de Waziers, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Effects of ethanol and clofibrate on expression of cytochrome P-450 enzymes and epoxide hydrolase in cultures and cocultures of rat hepatocytes.

P. Beaune, A. Guillouzo, I. de Waziers, 1991, European journal of biochemistry.

Engineered mesenchymal stem cells as vectors in a suicide gene therapy against preclinical murine models for solid tumors.

P. Beaune, E. Tartour, I. de Waziers, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.

P. Beaune, I. de Waziers, F. Berthou, 1996, Pharmacogenetics.

A suicide gene therapy combining the improvement of cyclophosphamide tumor cytotoxicity and the development of an anti-tumor immune response.

P. Beaune, E. Tartour, I. de Waziers, 2014, Current gene therapy.

Drug-metabolizing enzyme expression in human normal, peritumoral and tumoral colorectal tissue samples.

P. Beaune, I. de Waziers, A. Berger, 1991, Carcinogenesis.

Glutathione‐associated enzymes in head and neck squamous cell carcinoma and response to cisplatin‐based neoadjuvant chemotherapy

M. Loriot, P. Laurent-Puig, D. Brasnu, 2001, International journal of cancer.

P450 induction by Aroclor 1254 and 3,3',4,4'-tetrachlorobiphenyl in cultured hepatocytes from rat, quail and man: interspecies comparison.

I. de Waziers, J. Thomé, M. Dubois, 1996, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Induction of glucokinase mRNA by dietary phenolic compounds in rat liver cells in vitro.

I. de Waziers, Nhu-Traı̈ Truong, J. Ulrichová, 2007, Journal of agricultural and food chemistry.

CYP3A5 is the major cytochrome P450 3A expressed in human colon and colonic cell lines.

P. Beaune, I. de Waziers, A. Berger, 1996, Environmental toxicology and pharmacology.

Modification of hepatic drug-metabolizing enzymes in rat fed naturally occurring allyl sulphides.

P. Beaune, I. de Waziers, M. Suschetet, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

Presence of proteins recognized by mammalian cytochrome P-450 antibodies in Euglena gracilis.

P. Beaune, I. de Waziers, J. Briand, 1993, Biochimica et biophysica acta.

The activities of several detoxication enzymes are differentially induced by juices of garden cress, water cress and mustard in human HepG2 cells.

S. Lory, S. Rabot, I. de Waziers, 2004, Chemico-biological interactions.

Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis.

P. Beaune, I. de Waziers, J. G. Kenna, 1998, Chemico-biological interactions.

The effect of Smallanthus sonchifolius leaf extracts on rat hepatic metabolism

I. de Waziers, J. Ulrichová, K. Valentová, 2004, Cell Biology and Toxicology.

Insulin down-regulates cytochrome P450 2B and 2E expression at the post-transcriptional level in the rat hepatoma cell line.

P. Beaune, R. Barouki, I. de Waziers, 1995, Molecular pharmacology.

Detection and characterization of novel polymorphisms in the CYP2E1 gene.

I. de Waziers, J. Grove, C. Day, 1998, Pharmacogenetics.

Selective induction of the CYP3A family by endosulfan and DNA-adduct formation in different hepatic and hepatoma cells.

I. de Waziers, M. Dubois, P. Kremers, 1996, Environmental toxicology and pharmacology.

Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase pi in a rat hepatoma cell line (Fao).

P. Beaune, R. Barouki, I. de Waziers, 1992, Pharmacogenetics.

Microsatellite analysis and response to chemotherapy in head‐and‐neck squamous‐cell carcinoma

P. Beaune, P. Laurent-Puig, D. Brasnu, 1999, International journal of cancer.

Relation between inducibility of CYP1A1, GSTM1 and lung cancer in a French population.

P. Beaune, D. Hémon, I. de Waziers, 2000, Pharmacogenetics.

Regulatory sequence responsible for insulin destabilization of cytochrome P450 2B1 (CYP2B1) mRNA.

P. Beaune, R. Barouki, I. de Waziers, 2005, The Biochemical journal.

Immunogenic cell death in a combined synergic gene- and immune-therapy against cancer

P. Beaune, I. de Waziers, I. Amara, 2019, Oncoimmunology.

Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells.

P. Beaune, S. Imbeaud, I. de Waziers, 2009, Chemical research in toxicology.

Hepatic Intra-arterial Delivery of a “Trojan-horses” Gene Therapy: A Pilot Study on Rabbit VX2 Hepatic Tumor Model

P. Beaune, I. de Waziers, O. Pellerin, 2017, CardioVascular and Interventional Radiology.

Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes.

P. Beaune, I. de Waziers, J. Caldwell, 1997, Carcinogenesis.

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

P. Beaune, T. Asselah, P. Marcellin, 2007, Pharmacogenetics and genomics.

Knocking Down TMPRSS2-ERG Fusion Oncogene by siRNA Could be an Alternative Treatment to Flutamide

P. Couvreur, I. de Waziers, D. Desmaële, 2016, Molecular therapy. Nucleic acids.

Expression of cytochrome P‐450 3A in HT29‐MTX cells and Caco‐2 clone TC7

P. Beaune, A. Barbat, I. de Waziers, 1994, FEBS letters.

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

P. Beaune, I. de Waziers, C. S. Yang, 1990, The Journal of pharmacology and experimental therapeutics.

Induction of Cytochrome P450 2B6 and 3A4 Expression by Phenobarbital and Cyclophosphamide in Cultured Human Liver Slices

P. Beaune, P. Balladur, I. de Waziers, 2003, Pharmaceutical Research.

Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

M. Loriot, P. Beaune, C. Duyckaerts, 2009, Drug Metabolism and Disposition.

Combined Transcriptomic–1H NMR Metabonomic Study Reveals That Monoethylhexyl Phthalate Stimulates Adipogenesis and Glyceroneogenesis in Human Adipocytes

P. Beaune, I. de Waziers, Sandrine P. Claus, 2011, Journal of proteome research.

Colonization-Induced Host-Gut Microbial Metabolic Interaction

E. Want, L. Krause, P. van Bladeren, 2011, mBio.

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood–brain barrier

C. Daumas-Duport, R. Weaver, I. de Waziers, 2008, Journal of neurochemistry.

High levels of DNA adducts in human colon are associated with colorectal cancer.

P. Beaune, Y. Grosse, F. Carnot, 1995, Cancer research.

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.

R. Weaver, I. de Waziers, P. Couraud, 2009, Biochemical pharmacology.

SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION

P. Beaune, I. Bièche, I. Girault, 2005, Drug Metabolism and Disposition.

Pre- and postweaning development of drug-metabolizing enzyme activities in small intestine and liver of rats.

M. Boisset, I. de Waziers, S. Atteba, 1988, Drug Metabolism And Disposition.

Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma.

P. Beaune, I. de Waziers, F. Janot, 1993, Carcinogenesis.

Human CYP2B6: expression, inducibility and catalytic activities.

P. Beaune, H. Kroemer, V. Berardinis, 1999, Pharmacogenetics.

Human cytochromes P450 expressed in Escherichia coli: production of specific antibodies.

P. Beaune, I. de Waziers, J. Gautier, 1996, Toxicology.

Inter-individual variability in the oxidation of 1,2-dibromoethane: use of heterologously expressed human cytochrome P450 and human liver microsomes.

P. Beaune, N. Vermeulen, P. van Bladeren, 1996, Chemico-biological interactions.

GSTM1, smoking and lung cancer: a case-control study.

P. Beaune, D. Hémon, B. Milleron, 1999, International journal of epidemiology.

Cytochrome P450 induction and mutagenicity of 2-aminoanthracene (2AA) in rat liver and gut.

P. Beaune, I. de Waziers, V. Carrière, 1992, Mutation research.

Metabolism rate of oxodipine in rats and humans: comparison of in vivo and in vitro data.

P. Beaune, I. de Waziers, J. Flinois, 1992, The Journal of pharmacology and experimental therapeutics.

A repressive cross-regulation between catalytic and promoter activities of the CYP1A1 and CYP2E1 genes: role of H(2)O(2).

R. Barouki, I. de Waziers, Y Morel, 2000, Molecular pharmacology.

Improvement of Cyclophosphamide Activation by CYP2B6 Mutants: From in Silico to ex Vivo

Laurent Corcos, François André, Marcel Delaforge, 2008, Molecular Pharmacology.

The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: the case of ethylene dibromide.

P. Beaune, N. Vermeulen, P. van Bladeren, 1997, Toxicology and applied pharmacology.

Genotype identification of 10-day old Zucker rats by lipid content of inguinal fat pad.

I. de Waziers, E. Planche, M. Joliff, 1985, International journal of obesity.

Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

M. Loriot, P. Beaune, C. Duyckaerts, 2009, Drug Metabolism and Disposition.

Xenobiotic-Metabolizing Cytochromes P450 in Human White Adipose Tissue: Expression and Induction

P. Beaune, I. de Waziers, L. Pénicaud, 2010, Drug Metabolism and Disposition.

Formation of mutagenic derivatives from tryptophan pyrolysis products (Trp P1 and Trp P2) by rat intestinal S9 fraction.

I. de Waziers, F. Decloitre, 1983, Mutation research.

Effect of glutathione and uridine-5'-diphosphoglucuronic acid on the mutagenicity of tryptophan pyrolysis products (Trp-P-1 and Trp-P-2) by rat-liver and -intestine S9 fraction.

I. de Waziers, F. Decloitre, 1984, Mutation research.