A. Pao

发表

Preferential Formation of Benzo[a]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

M. Tang, G. Pfeifer, M. Denissenko, 1996, Science.

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.

George Stoica, Shaomin Li, Allan Bradley, 2010, Human molecular genetics.

Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models.

B. Tycko, N. Schupf, W. Silverman, 2020, Progress in brain research.

Mouse-based genetic modeling and analysis of Down syndrome.

B. Tycko, W. Mobley, A. Pao, 2016, British medical bulletin.

Cyclobutane Pyrimidine Dimers and Bulky Chemical DNA Adducts Are Efficiently Repaired in Both Strands of Either a Transcriptionally Active or Promoter-deleted APRT Gene*

M. Tang, A. Pao, G. Adair, 2001, The Journal of Biological Chemistry.

Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors

G. Stoica, P. Wallace, A. Pao, 2017, Oncotarget.

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability.

L. Mei, A. Pao, K. Sossey-Alaoui, 2010, Human molecular genetics.

Increased Insulin Action in SKIP Heterozygous Knockout Mice

A. Bradley, T. Takenawa, A. Pao, 2008, Molecular and Cellular Biology.

Coat Color-Facilitated Efficient Generation and Analysis of a Mouse Model of Down Syndrome Triplicated for All Human Chromosome 21 Orthologous Regions

A. Pao, Tao Yu, Y. E. Yu, 2021, Genes.

Formation and repair of antitumor antibiotic CC-1065-induced DNA adducts in the adenine phosphoribosyltransferase and amplified dihydrofolate reductase genes of Chinese hamster ovary cells.

M. Tang, A. Pao, M. Qian, 1994, Biochemistry.

Repair of benzo(a)pyrene diol epoxide- and UV-induced DNA damage in dihydrofolate reductase and adenine phosphoribosyltransferase genes of CHO cells.

M. Tang, A. Pao, X. Zhang, 1994, The Journal of biological chemistry.

Neuronal differentiation of NTE-deficient embryonic stem cells.

A. Bradley, A. Pao, Zhongyou Li, 2005, Biochemical and biophysical research communications.

Ultraviolet irradiation induces BRCA2 protein depletion through a p53-independent and protein synthesis-dependent pathway.

K. Makino, M. Hung, L. Su, 2001, Cancer research.

Advances in Brief Ultraviolet Irradiation Induces BRCA 2 Protein Depletion through a p 53-independent and Protein Synthesis-dependent Pathway 1

K. Makino, M. Hung, Shao-Chun Wang, 2001 .

Genetic analysis of Down syndrome facilitated by mouse chromosome engineering

W. Mobley, A. Pao, S. Clapcote, 2012, Bioengineered bugs.

Genetic control of capsid length in bacteriophage T4: phenotypes displayed by ptg mutants

A. Pao, A. Doermann, 1987, Journal of virology.

Genetic control of capsid length in bacteriophage T4: clustering of ptg mutations in gene 23

A. Pao, A. Doermann, P. Jackson, 1987, Journal of virology.

Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits.

P. Ye, S. Josselyn, W. Mobley, 2014, Human molecular genetics.

Mapping polycyclic aromatic hydrocarbon and aromatic amine-induced DNA damage in cancer-related genes at the sequence level.

M. Tang, G. Pfeifer, Wenwei Hu, 2002, International journal of hygiene and environmental health.

Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer.

William Rom, W. Rom, M. Hung, 2002, Journal of the National Cancer Institute.

Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice

P. Ye, M. Morishima, A. Pao, 2014, Human Genetics.

Genetic analysis of Down syndrome-associated heart defects in mice

Li Zhang, Antonio Baldini, N. Nowak, 2011, Human Genetics.

Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities.

N. Nowak, M. Morishima, J. Conroy, 2007, Human molecular genetics.

Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice

J. Roder, A. Bradley, A. Baldini, 2010, Mammalian Genome.

A Deficiency in the Region Homologous to Human 17q21.33–q23.2 Causes Heart Defects in Mice

A. Bradley, A. Baldini, M. Morishima, 2006, Genetics.

Genetic dissection of the Down syndrome critical region.

Jennifer L. Peresie, W. Mobley, A. Pao, 2015, Human molecular genetics.

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

J. Roder, A. Baldini, W. Mobley, 2010, Brain Research.

Analysis of mutations in primary and metastatic synovial sarcoma

C. Morrison, Jianmin Wang, Song Liu, 2018, Oncotarget.

Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers

M. Tang, G. Pfeifer, M. Denissenko, 1998, Oncogene.

Transcription-coupled DNA Repair Is Genomic Context-dependent*

Elena Komissarova, M. Hung, M. Tang, 2002, The Journal of Biological Chemistry.

Inhibition of cancer cell growth by BRCA2.

M. Hung, Shao-Chun Wang, L. Su, 2002, Cancer research.

CRISPR/Cas9-Facilitated Chromosome Engineering to Model Human Chromosomal Alterations

A. Pao, Y. E. Yu, Zhuo Xing, 2018 .

Dissection of a down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.

Jianlin Cheng, B. Tycko, Song Liu, 2023, Human molecular genetics.

Increased Insulin Action in SKIP Heterozygous Knockout Mice

A. Bradley, T. Takenawa, A. Pao, 2008, Molecular and Cellular Biology.