C. Mol

发表

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

John A. Tainer, J. Tainer, C. Mol, 1995, Nature.

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

R. Abagyan, R. Stevens, Wei Liu, 2010, Science.

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.

J. R. Somoza, D. McRee, Biching Sang, 2004, Structure.

Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae

D. McRee, C. Mol, R. Swanson, 2003, Journal of bacteriology.

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil‐DNA glycosylase with DNA

J. Tainer, C. Mol, H. Krokan, 1998, The EMBO journal.

Envisioning the molecular choreography of DNA base excision repair.

J. Tainer, C. Mol, D. Hosfield, 1999, Current opinion in structural biology.

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra‐helical deoxyribose at DNA abasic sites

J. Tainer, P. Freemont, E. de La Fortelle, 1997, The EMBO journal.

DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination

J. Tainer, C. Mol, S. Mitra, 2000, Nature.

Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means.

J. Tainer, C. Mol, D. Hosfield, 2000, Mutation research.

Targeting inactive kinases: structure as a foundation for cancer drug discovery

C. Mol, D. Hosfield, 2008 .

MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily

J. Tainer, Jeffrey H. Miller, R. Lloyd, 1998, Nature Structural Biology.

Sequencing and modeling of anti-DNA immunoglobulin Fv domains. Comparison with crystal structures.

C. Mol, W. Anderson, J. S. Lee, 1994, The Journal of biological chemistry.

Insights into selectivity of STI571 [GleevecTM] from X-ray crystallography

K. Wilson, D. McRee, Devon A. Thompson, 2003 .

Haemophilus influenzae Acid : l-Alanine Ligase ( MurC ) from-Acetylmuramic N Complexes of UDP-Assembled Substrate-and Product-Bound Crystal Structures of Active Fully

D. McRee, C. Mol, R. Swanson, 2003 .

Residues that mediate DNA binding of autoimmune antibodies.

W. Anderson, M. Radic, C. Mol, 1993, Journal of immunology.

Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors.

C. Mol, V. Feher, Lihong Shi, 2010, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors.

Biching Sang, C. Mol, D. Dougan, 2011, Bioorganic & medicinal chemistry letters.

structural in non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

J. Tainer, M. Pique, C. Mol, 2013 .

2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability.

J. Kunitomo, Toshimasa Tanaka, C. Mol, 2009, Journal of medicinal chemistry.

Design, synthesis and structure-activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta.

J. Kunitomo, Toshimasa Tanaka, C. Mol, 2009, Bioorganic & medicinal chemistry.

A new class of non-thiazolidinedione, non-carboxylic-acid-based highly selective peroxisome proliferator-activated receptor (PPAR) γ agonists: design and synthesis of benzylpyrazole acylsulfonamides.

Toshimasa Tanaka, Biching Sang, C. Mol, 2012, Bioorganic & medicinal chemistry.

Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding

J. Tainer, C. Mol, A. Pegg, 2000, The EMBO journal.

Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation*

E. Chien, D. Kassel, D. McRee, 2003, Journal of Biological Chemistry.

Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase*

K. Wilson, Biching Sang, C. Mol, 2004, Journal of Biological Chemistry.

DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes.

J. Tainer, C. Mol, C. Putnam, 2001, Progress in nucleic acid research and molecular biology.

DNA repair mechanisms for the recognition and removal of damaged DNA bases.

J. Tainer, C. Mol, C. Putnam, 1999, Annual review of biophysics and biomolecular structure.

Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis

J. Tainer, C. Mol, H. Krokan, 1995, Cell.

Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.

J. Tainer, T. Begley, C. Mol, 2002, Journal of molecular biology.

Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: Protein mimicry of DNA

J. Tainer, C. Mol, H. Krokan, 1995, Cell.

Structural Phylogenetics of DNA Base Excision Repair

J. Tainer, C. Mol, S. S. Parikh, 1998 .

Structural and functional homology of parvovirus and papovavirus polypeptides.

W. Anderson, C. Mol, W. Anderson, 1987, The Journal of general virology.

Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway.

J. Tainer, C. Mol, S. S. Parikh, 1997, Structure.

Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.

C. Mol, M. Yabuki, Sei Yoshida, 2013, Bioorganic & medicinal chemistry.

Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits.

J. Tainer, C. Mol, Jonathan M. Harris, 1996, Structure.

Switching on kinases: oncogenic activation of BRAF and the PDGFR family

C. Mol, S. Dilworth, N. Dibb, 2004, Nature Reviews Cancer.

Structure of the DNA Repair and Replication Endonuclease and Exonuclease FEN-1 Coupling DNA and PCNA Binding to FEN-1 Activity

J. Tainer, C. Mol, D. Hosfield, 1998, Cell.

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected].

J. Tainer, C. Mol, S. Mitra, 2000, Nature.

Structure and Function of the DNA Repair Enzyme Exonuclease III from E. Coli a

C. Mol, C. Kuo, M. M. Thayer, 1994, Annals of the New York Academy of Sciences.

Structural insights into the conformational selectivity of STI-571 and related kinase inhibitors.

D. Fabbro, C. Mol, D. Hosfield, 2004, Current opinion in drug discovery & development.

A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA

J. Tainer, C. Mol, H. Krokan, 1996, Nature.

Excision of cytosine and thymine from DNA by mutants of human uracil‐DNA glycosylase.

J. Tainer, C. Mol, H. Krokan, 1996, The EMBO journal.

Structure of an I ~ ~ ~ n ~ ~ i n Fab Fragment Specific for ~p~emstranded DNA*

C. Mol, Wayne, Miroslaw Cyglerll, 2001 .

Structure of an immunoglobulin Fab fragment specific for poly(dG).poly(dC).

C. Mol, W. Anderson, J. S. Lee, 1994, The Journal of biological chemistry.

Structure of an immunoglobulin Fab fragment specific for triple-stranded DNA.

C. Mol, W. Anderson, J. S. Lee, 1994, The Journal of biological chemistry.

Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase.

J. Tainer, C. Mol, C. Putnam, 1999, Journal of molecular biology.

erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination

John A. Tainer, Tadahide Izumi, J. Tainer, 2000, Nature.

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1

J. Tainer, C. Robson, I. Hickson, 1995, Nature Structural Biology.

Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes*

J. Tainer, M. Pique, K. Frankel, 2013, The Journal of Biological Chemistry.

Structure-activity relationships and key structural feature of pyridyloxybenzene-acylsulfonamides as new, potent, and selective peroxisome proliferator-activated receptor (PPAR) γ Agonists.

Toshimasa Tanaka, Biching Sang, C. Mol, 2012, Bioorganic & medicinal chemistry.

Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor

C. Mol, S. Ghaem-Maghami, N. Brownlow, 2008, Leukemia.

HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA

J. Tainer, C. Mol, S. Mitra, 2000 .

The importance of purity in the crystallization of DNA binding immunoglobulin Fab fragments

A. Boodhoo, C. Mol, W. Anderson, 1988 .

Beili Wu Cyclic Peptide Antagonists Structures of the CXCR 4 Chemokine GPCR with Small-Molecule and

R. Abagyan, R. Stevens, Wei Liu, 2011 .

Toshimasa Tanaka, Biching Sang, C. Mol, 2012, Bioorganic & medicinal chemistry.

Crystal structure of the CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15

R. Stevens, Wei Liu, V. Katritch, 2010 .

Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes*

J. Tainer, M. Pique, K. Frankel, 2013, The Journal of Biological Chemistry.