M. Nau

发表

p53: a frequent target for genetic abnormalities in lung cancer.

J. Minna, A. Gazdar, A. Gazdar, 1989, Science.

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer.

T. Unger, J. Minna, T. Unger, 1992, The EMBO journal.

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors.

J. Minna, A. Gazdar, D. Carbone, 1992, Oncogene.

Ovarian Cancer Cell Lines that Overexpress erbB2 Apoptosis-inducing Ligand-mediated Apoptosis in Breast and ( Herceptin ) Enhances Tumor Necrosis Factor-related Down-Regulation of the erbB2 Receptor by Trastuzumab

P. Dennis, M. Nau, S. Lipkowitz, 2001 .

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

J. Minna, A. Gazdar, M. Nau, 1983, Nature.

Mutations in the p53 gene in primary human breast cancers.

G. Merlo, T. Mitsudomi, T. Venesio, 1991, Cancer research.

Nonrandom structural and numerical chromosome changes in non‐small‐cell lung cancer

S. Steinberg, J. Minna, A. Gazdar, 1991, Genes, chromosomes & cancer.

Chemotherapy augments TRAIL-induced apoptosis in breast cell lines.

M. Nau, E. Russell, S. Lipkowitz, 1999, Cancer research.

Cbl-3-Deficient Mice Exhibit Normal Epithelial Development

R. Khokha, J. Penninger, O. Sanchez, 2003, Molecular and Cellular Biology.

Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation.

J. Minna, A. Gazdar, A. Gazdar, 1992, Oncogene.

Regulating the regulator: negative regulation of Cbl ubiquitin ligases.

M. Nau, S. Lipkowitz, Philip E. Ryan, 2006, Trends in biochemical sciences.

The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme*

M. Nau, S. Nicholas, S. Lipkowitz, 2010, The Journal of Biological Chemistry.

Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer

J. Battey, E. Sausville, J. Minna, 1988, Molecular and cellular biology.

Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing

J. Battey, E. Sausville, J. Minna, 1988, Molecular and cellular biology.

Recessive oncogenes and chromosomal deletions in human lung cancer

J. Minna, A. Gazdar, F. Kaye, 1989 .

Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.

O. Olopade, J. Minna, A. Gazdar, 1993, Cancer research.

Advances in Brief Wild-type but not Mutant p 53 Suppresses the Growth of Human Lung Cancer Cells Bearing Multiple Genetic Lesions 1

J. Minna, D. Carbone, R. Ueda, 2006 .

Biological heterogeneity of small cell lung cancer.

J. Minna, A. Gazdar, M. Nau, 1985, Seminars in oncology.

Recombination events that activate, diversify, and delete immunoglobulin genes.

J. Seidman, P. Leder, E. E. Max, 1981, Cold Spring Harbor symposia on quantitative biology.

N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines

M. Birrer, J. Liu, M. Nau, 2004, Cell Death and Differentiation.

Inhibition of NF-κB Activity Enhances TRAIL Mediated Apoptosis in Breast Cancer Cell Lines

M. Nau, S. Lipkowitz, M. Cuello, 2000, Breast Cancer Research and Treatment.

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

N. Caplen, M. Nau, S. Lipkowitz, 2014, Breast Cancer Research.

Additive and differential biological activity of alpha-interferon A, difluoromethylornithine, and their combination on established human lung cancer cell lines.

G. Bepler, J. Minna, A. Gazdar, 1986, Cancer research.

Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer

J. Minna, A. Gazdar, A. Gazdar, 1989, International journal of cancer. Supplement = Journal international du cancer. Supplement.

THE ORGANIZATION OF IMMUNOGLOBULIN GENES

P. Leder, T. Honjo, M. Nau, 1974 .

Absence of hereditary p53 mutations in 10 familial leukemia pedigrees.

J. Fraumeni, J. Whang‐Peng, C. Felix, 1992, The Journal of clinical investigation.

Multiple Mechanisms forTranscriptional Regulation ofthemyc GeneFamily inSmall-Cell LungCancer

E. Sausville, J. Minna, M. Nau, 1988 .

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

J. Minna, S. Piantadosi, D. Carbone, 1990, Oncogene.

myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.

R. Makuch, J. Minna, A. Gazdar, 1987, The Journal of clinical investigation.

Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b

M. Nau, S. Lipkowitz, S. Ettenberg, 2004, Oncogene.

THE ORGANIZATION AND DIVERSITY OF IMMUNOGLOBULIN κ AND λ GENES

P. Leder, T. Honjo, M. Nau, 1975 .

Mutations in dominant and recessive oncogenes, and the expression of opioid and nicotine receptors in the pathogenesis of lung cancer

S. Steinberg, J. Minna, A. Gazdar, 1991 .

Amplification, expression and rearrangement of c-myc and N-myc oncogenes in human lung cancer.

J. Battey, J. Minna, A. Gazdar, 1984, Current topics in microbiology and immunology.

Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5

M. Nau, Stephen C. Kales, S. Lipkowitz, 2012, PloS one.

Translation and translocation of defined RNA messengers.

P. Leder, M. Nau, R. Erbe, 1969, Journal of molecular biology.

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

J. Minna, M. Nau, J. Fedorko, 1989, Cell.

Human small-cell lung cancers show amplification and expression of the N-myc gene.

J. Battey, E. Sausville, J. Minna, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.

Stephen C Kales, M. Nau, Stephen C. Kales, 2010, Cancer research.

Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex*

Y. Yarden, M. Nau, A. Weissman, 2001, The Journal of Biological Chemistry.

Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties.

J. Minna, A. Gazdar, A. Gazdar, 1985, Cancer research.

Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2.

P. Dennis, M. Nau, S. Lipkowitz, 2001, Cancer research.

cbl-b inhibits epidermal growth factor receptor signaling

M. Nau, S. Lipkowitz, S. Ettenberg, 1999, Oncogene.

Molecular genetic analysis reveals chromosomal deletion, gene amplification, and autocrine growth factor production in the pathogenesis of human lung cancer.

J. Battey, J. Minna, A. Gazdar, 1986, Cold Spring Harbor symposia on quantitative biology.

LINE‐I element insertion at the t(11;22) translocation breakpoint of a desmoplastic small round cell tumor

J. Powell, J. Zucman‐Rossi, C. Allegra, 1997, Genes, chromosomes & cancer.

Cloning and Characterization of the 5 ' Upstream Region of the Human Primary Response Gene EGR-3

P. Brown, C. Allegra, M. Nau, 2016 .

Differential expression of myc family genes during murine development

F. Alt, J. Minna, G. Yancopoulos, 1986, Nature.

p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.

S. Steinberg, J. Minna, A. Gazdar, 1992, Oncogene.

Molecular genetic characterization of neuroendocrine lung cancer cell lines.

F. Kaye, H. Brauch, B. Zbar, 1995, Anticancer research.

Physical interaction between p53 and primary response gene Egr-1.

C. Allegra, M. Nau, E. Chu, 2001, International journal of oncology.

Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.

M. Nau, S. Lipkowitz, M. Cuello, 2001, Gynecologic oncology.

Molecular heterogeneity and function of EWS-WT1 fusion transcripts in desmoplastic small round cell tumors.

C. Allegra, M. Nau, E. Chu, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors.

M. Nau, S. Lipkowitz, S. Ettenberg, 1999, Molecular cell biology research communications : MCBRC.

Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

M. Nau, S. Lipkowitz, M. Cuello, 2000, Breast cancer research and treatment.

The organization and diversity of immunoglobulin genes.

P. Leder, T. Honjo, M. Nau, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.

S P Kwan, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Frequency and Diversity of P53 Mutations in Childhood Updated Version Citing Articles E-mail Alerts Frequency and Diversity of P53 Mutations in Childhood Rhabdomyosarcoma

C. Felix, T. Mitsudomi, M. Nau, 1992 .

Characterization of light chain and light chain constant region fragment mRNAs in MPC 11 mouse myeloma cells and variants

P. Leder, T. Honjo, W. Kuehl, 1975, Cell.

Cbl as a Master Regulator of Receptor Tyrosine Kinase Trafficking

M. Nau, Stephen C. Kales, S. Lipkowitz, 2013 .

Initiation of protein synthesis. 3. Factor-GTP-codon-dependent binding of F-met-tRNA to ribosomes.

P. Leder, M. Nau, 1967, Proceedings of the National Academy of Sciences of the United States of America.

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

P. Meltzer, S. Davis, J. Pumphrey, 2008, Breast Cancer Research and Treatment.

Translocation of mRNA codons. I. The preparation and characteristics of a homogeneous enzyme.

P. Leder, M. Nau, L. Skogerson, 1969, Proceedings of the National Academy of Sciences of the United States of America.

THE ARRANGEMENT, REARRANGEMENT AND ORIGIN OF IMMUNOGLOBULIN GENES

J. Seidman, P. Leder, E. E. Max, 1979 .

Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A

M. Nau, Stephen C. Kales, S. Lipkowitz, 2014, PloS one.

cbl-3: a new mammalian cbl family protein

J. Penninger, M. Nau, S. Lipkowitz, 1999, Oncogene.

Comparative genomic organization of the cbl genes.

M. Nau, S. Lipkowitz, 2003, Gene.

Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines

K. Alitalo, M. Kelley, T. Mäkelä, 1998, Oncogene.

Wild-type but not mutant p53 suppresses the growth of human lung cancer cells bearing multiple genetic lesions.

T Takahashi, J. Minna, D. Carbone, 1992, Cancer research.

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

J. Battey, E. Sausville, J. Minna, 1985, Nature.

Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.

P. Leder, T. Honjo, M. Nau, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Differentiation stages of childhood acute lymphoblastic leukemias with p53 mutations.

J. Minna, C. Felix, M. Nau, 1994, Leukemia.

Constitutive expression of multiple messenger rna forms of the c jun oncogene in human lung cancer cell lines

J. Minna, A. Gazdar, M. Nau, 1988 .

A novel germline p53 splicing mutation in a pediatric patient with a second malignant neoplasm.

C. Felix, T. Mitsudomi, M. Nau, 1993, Oncogene.

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

N. Caplen, M. Nau, S. Lipkowitz, 2014, Breast Cancer Research.

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.

J. Whang‐Peng, T. Mitsudomi, Takashi Takahashi, 1992, The Journal of clinical investigation.

Loss of function Cbl-c mutations in solid tumors

M. Nau, S. Daniels, Jeffrey E. Green, 2019, PloS one.

Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.

J. Battey, E. Sausville, J. Minna, 1986, Princess Takamatsu symposia.

Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.

M. Nau, Stephen C. Kales, S. Lipkowitz, 2010, Cancer Research.