H. Arakawa

发表

p53AIP1, a Potential Mediator of p53-Dependent Apoptosis, and Its Regulation by Ser-46-Phosphorylated p53

Yusuke Nakamura, C. Tanikawa, K. Matsuda, 2000, Cell.

p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis.

Y Taya, M Monden, Y. Nakamura, 2001, Molecular cell.

Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53

Yusuke Nakamura, H. Arakawa, Toshiki Mori, 2002, Oncogene.

Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53

Yusuke Nakamura, H. Arakawa, K. Ueda, 2003, Oncogene.

Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

Yusuke Nakamura, Kyong-Ah Yoon, Yusuke Nakamura, 2004, Journal of Human Genetics.

Identification of semaphorin3B as a direct target of p53.

Yusuke Nakamura, Toshiki Mori, Yoshiaki Toyama, 2002, Neoplasia.

Identification of Fractalkine , a CX 3 C-type Chemokine , as a Direct Target of p 531

Yusuke Nakamura, C. Tanikawa, K. Matsuda, 2000 .

Isolation and characterization of defective-interfering particles of poliovirus Sabin 1 strain.

S. Kuge, H. Arakawa, S. Kajigaya, 1985, Virology.

Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer

C. Croce, M. Mori, H. Arakawa, 2002, Oncogene.

Mieap forms membrane-less organelles to compartmentalize and facilitate cardiolipin metabolism

H. Arakawa, Yasuyuki Nakamura, Naoki Ikari, 2020, bioRxiv.

Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system.

Y. Nakamura, M. Monden, H. Arakawa, 1999, Oncology research.

Counteraction of pRb‐dependent protection after extreme hypoxia by elevated ribonucleotide reductase

Y. Nakamura, T. Stokke, H. Arakawa, 2004, Cell proliferation.

Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway

Yusuke Nakamura, H. Nakagawa, H. Arakawa, 2004, Oncogene.

Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method.

Y. Nakamura, H. Nagase, H. Arakawa, 1994, Cancer research.

Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

Y. Nakamura, Y. Kanai, H. Arakawa, 2016, Oncogenesis.

MIEAP, a p53-downstream gene, is associated with suppression of breast cancer cell proliferation and better survival.

Kazuhiro Yoshida, H. Arakawa, K. Takabe, 2022, American journal of cancer research.

Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression.

T. Ushijima, M. Ohira, Yohko Nakamura, 2013, The Journal of clinical investigation.

hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53

Yusuke Nakamura, H. Arakawa, M. Gotoh, 2003, Cancer science.

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.

H. Nagase, H. Arakawa, M. Ogawa, 1994, Human molecular genetics.

Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis.

Y. Nakamura, H. Nakagawa, Y. Miyoshi, 2000, Genes, chromosomes & cancer.

Mieap, a p53-Inducible Protein, Controls Mitochondrial Quality by Repairing or Eliminating Unhealthy Mitochondria

S. Ichinose, H. Arakawa, Masaki Yoshida, 2011, PloS one.

p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint.

Y. Nakamura, K. Matsuda, H. Arakawa, 2001, Cancer research.

Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene.

C. Croce, M. Shimizu, F. Bullrich, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of a novel gene on 8p21.3–22 whose expression is reduced significantly in human colorectal cancers with liver metastasis

Yusuke Nakamura, H. Nakagawa, Y. Miyoshi, 2000 .

K1 gene transformation activities in AIDS-related and classic type Kaposi’s sarcoma: Correlation with clinical presentation

H. Arakawa, M. Tsuneki, Sayaka Yamaguchi, 2019, Scientific Reports.

Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kDa (hFKBP-12) and characterization of two alternatively spliced transcripts.

Y. Nakamura, T. Fujiwara, H. Nagase, 1994, Biochemical and biophysical research communications.

p 53 R 2-dependent Pathway for DNA Synthesis in a p 53-regulated Cell Cycle Checkpoint 1

Yusuke Nakamura, K. Matsuda, H. Arakawa, 2001 .

MIEAP and ATG5 are tumor suppressors in a mouse model of BRAFV600E-positive thyroid cancer

H. Arakawa, Yasuyuki Nakamura, K. Hamada, 2022, Frontiers in Endocrinology.

Mammalian p53R2 Protein Forms an Active Ribonucleotide Reductasein Vitro with the R1 Protein, Which Is Expressed Both in Resting Cells in Response to DNA Damage and in Proliferating Cells*

Yusuke Nakamura, H. Arakawa, A. Gräslund, 2001, The Journal of Biological Chemistry.

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

Yusuke Nakamura, H. Arakawa, S. Fukuda, 2000, Nature.

BNIP3 and NIX Mediate Mieap-Induced Accumulation of Lysosomal Proteins within Mitochondria

H. Arakawa, Masaki Yoshida, Yasuyuki Nakamura, 2012, PloS one.

p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1

Yusuke Nakamura, H. Arakawa, C. Ng, 2003, Oncogene.

The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage

M. Ohki, H. Arakawa, T. Kiyono, 2006, Journal of Human Genetics.

Survivin: A novel marker and potential therapeutic target for human angiosarcoma

H. Arakawa, N. Yamazaki, K. Kuyama, 2017, Cancer science.

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

Yusuke Nakamura, Véronique Paquis-Flucklinger, Arnold Munnich, 2007, Nature Genetics.

K1 gene transformation activities in AIDS-related and classic type Kaposi’s sarcoma: Correlation with clinical presentation

H. Arakawa, M. Tsuneki, Sayaka Yamaguchi, 2019, Scientific Reports.

Cyclin K as a direct transcriptional target of the p53 tumor suppressor.

Yusuke Nakamura, H. Arakawa, Toshiki Mori, 2002, Neoplasia.

NuMA Is Required for the Selective Induction of p53 Target Genes

T. Nagase, J. Yokota, M. Miyazaki, 2013, Molecular and Cellular Biology.

Netrin-1 and its receptors in tumorigenesis

H. Arakawa, Hirofumi Arakawa, 2004, Nature Reviews Cancer.

Infrequent Somatic Mutation of the MTS1 Gene in Primary Bladder Carcinomas

Yusuke Nakamura, H. Arakawa, M. Ogawa, 1995, Japanese journal of cancer research : Gann.

p53AIP1 regulates the mitochondrial apoptotic pathway.

Kozo Nakamura, Yusuke Nakamura, K. Matsuda, 2002, Cancer research.

p 53 AIP 1 Regulates the Mitochondrial Apoptotic Pathway 1

Kozo Nakamura, Yusuke Nakamura, K. Matsuda, 2002 .

Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression

H. Arakawa, T. Kiyono, N. Goshima, 2017, Carcinogenesis.

p53, apoptosis and axon-guidance molecules

H. Arakawa, 2005, Cell Death and Differentiation.

Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.

T. Katagiri, Y. Nakamura, K. Matsuda, 2000, Cancer research.

Identification of fractalkine, a CX3C-type chemokine, as a direct target of p53.

C. Tanikawa, Y. Nakamura, K. Matsuda, 2000, Cancer research.

XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway

Y. Furukawa, C. Tanikawa, Y. Nakamura, 2009, Oncogene.

Tokuda Akihiro Tomida Shinya Toyokuni Hitoshi Tsuda Shoichiro Tsugane Tatsuhiko Tsunoda Heiichiro Udono Koji Ueda Yoshimasa Uehara Hiroo Ueno Kazuo Umezawa Toshikazu Ushijima Toshihiko Wakabayashi Kenji Wakai Tetsuro Watabe

H. Aburatani, S. Hirota, Y. Kaneda, 2016 .

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes

Yutaka Suzuki, T. Shibata, S. Marubashi, 2016, Carcinogenesis.

Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.

Yusuke Nakamura, H. Arakawa, Toshiki Mori, 2002, Cancer research.

Discovery of Mieap‐regulated mitochondrial quality control as a new function of tumor suppressor p53

H. Arakawa, Yasuyuki Nakamura, 2017, Cancer science.

Identification of p53–46F as a super p53 with an enhanced ability to induce p53‐dependent apoptosis

H. Arakawa, Koji Yoshida, Y. Nakamura, 2006, Cancer science.

Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

H. Arakawa, Naoki Ikari, 2023, bioRxiv.

Possible role of p53/Mieap‐regulated mitochondrial quality control as a tumor suppressor in human breast cancer

Kazuhiro Yoshida, H. Arakawa, M. Futamura, 2018, Cancer science.

Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression.

H. Arakawa, Yasuyuki Nakamura, S. Ohnishi, 2007, Cancer research.

Adenovirus‐mediated p53AIP1 gene transfer as a new strategy for treatment of p53‐resistant tumors

Yusuke Nakamura, M. Monden, H. Arakawa, 2004, Cancer science.

Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

Yusuke Nakamura, H. Arakawa, M. Gotoh, 2003, Nature Genetics.

p53RDL1 regulates p53-dependent apoptosis

Yusuke Nakamura, C. Tanikawa, K. Matsuda, 2003, Nature Cell Biology.

Possible Existence of Lysosome-Like Organella within Mitochondria and Its Role in Mitochondrial Quality Control

S. Ichinose, H. Arakawa, M. Ono, 2011, PloS one.

Germ‐line and somatic mutations of the APC gene in patients with turcot syndrome and analysis of APC mutations in brain tumors

Yusuke Nakamura, M. Shibuya, Y. Hayashi, 1994, Genes, chromosomes & cancer.

B‐cell linker protein prevents aneuploidy by inhibiting cytokinesis

H. Arakawa, Yasuyuki Nakamura, M. Futamura, 2008, Cancer science.

Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA.

Y. Nakamura, T. Fujiwara, H. Nagase, 1995, Cytogenetics and cell genetics.

Significant increase of adenovirus infectivity in glioma cell lines by extracellular domain of hCAR.

T. Tokino, K. Mineura, H. Arakawa, 1999, Oncology research.

The APC (adenomatous polyposis coli) gene: A novel mutation in an FAP patient and a DdeI polymorphism in the 5′ noncoding region

H. Arakawa, S. Mori, T. Nishihira, 1993, Human mutation.

Mieap suppresses murine intestinal tumor via its mitochondrial quality control

H. Arakawa, Yasuyuki Nakamura, M. Tsuneki, 2015, Scientific Reports.

p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers.

Kazuhiro Yoshida, H. Arakawa, Yasuyuki Nakamura, 2020, Biochemical and biophysical research communications.

Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control

H. Arakawa, M. Ono, Masaki Yoshida, 2012, Scientific Reports.

Recent advances and new perspectives in mitochondrial dysfunction

H. Arakawa, C. Giulivi, Kezhong Zhang, 2023, Scientific reports.