S. Benchimol

发表

Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis

Yunping Lin, Weili Ma, S. Benchimol, 2000, Nature Genetics.

Regulation of PTEN transcription by p53.

T. Mak, Yunping Lin, S. Benchimol, 2001, Molecular cell.

p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest

Weili Ma, S. Benchimol, J. Ho, 2005, Molecular and Cellular Biology.

A functional wild-type p53 gene is expressed in human acute myeloid leukemia cell lines.

S. Benchimol, T. Sutcliffe, L. Fu, 1998, Blood.

A Functional Wild-Type p53 Gene Is Expressed in Human Acute Myeloid Leukemia Cell Lines

S. Benchimol, T. Sutcliffe, L. Fu, 1998 .

S Benchimol not p 53-mediated G 1 arrest . Cytokines inhibit p 53-mediated apoptosis but

Yunping Lin, S. Benchimol, 1995 .

The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras

R. Bristow, S. Benchimol, J. Peacock, 1995, Molecular and cellular biology.

Cytokines inhibit p53-mediated apoptosis but not p53-mediated G1 arrest

S. Benchimol, Y. Lin, 1995, Molecular and cellular biology.

Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

Guillermina Lozano, R. Hakem, G. Lozano, 2003, Cell.

Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents.

R. Bristow, F. Jalali, S. Benchimol, 2002, Experimental cell research.

Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

S. Benchimol, P. Johnson, S. Chung, 1993 .

Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

S. Benchimol, S. Chung, P. Johnson, 1993, Molecular and cellular biology.

The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.

S. Benchimol, J. Jenkins, J. Slingerland, 1993, The EMBO journal.

Transcriptional repression mediated by the p53 tumour suppressor

S. Benchimol, J. Ho, S Benchimol, 2003, Cell Death and Differentiation.

Poly(ADP-ribose) Polymerase-1 Is a Positive Regulator of the p53-mediated G1 Arrest Response following Ionizing Radiation*

S. Benchimol, H. Vaziri, Sonya Wieler, 2003, Journal of Biological Chemistry.

p53-dependent pathways of apoptosis

S. Benchimol, 2001, Cell Death and Differentiation.

p53: oncogene or anti-oncogene?

D. Lane, S. Benchimol, D P Lane, 1990, Genes & development.

HDAC5--a critical player in the p53 acetylation network.

S. Benchimol, S. S. Kim, 2013, Molecular cell.

The death-promoting activity of p53 can be inhibited by distinct signaling pathways.

D. Hedley, Yunping Lin, S. Benchimol, 2002, Blood.

Inactivation of the cellular p53 gene is a common feature of Friend virus-induced erythroleukemia: relationship of inactivation to dominant transforming alleles

S. Benchimol, J. Peacock, D. Munroe, 1990, Molecular and cellular biology.

Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome

Grant W. Brown, Weili Ma, S. Benchimol, 2017, Molecular and Cellular Biology.

Abnormalities of the ARF-p53 pathway in oral squamous cell carcinoma

K. Mancer, S. Kamel‐Reid, P. Gullane, 2001, Oncogene.

The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma

P. Gullane, J. Irish, S. Benchimol, 2007, British Journal of Cancer.

p53 protein expression or protein function?

R. Bristow, S. Benchimol, R. Hill, 1996, International journal of radiation oncology, biology, physics.

p53 Protein expression or protein function? Re: Awwad et al. IJROBP 34(2):323–332; 1996

R. Bristow, S. Benchimol, R. Hill, 1996 .

Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation

R. Bristow, S. Benchimol, J. Peacock, 1998, Oncogene.

Loss of a highly conserved domain on p53 as a result of gene deletion during Friend virus-induced erythroleukemia.

A. Bernstein, S. Benchimol, D. Munroe, 1988, Oncogene.

Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus.

A. Bernstein, S. Benchimol, V. Chow, 1988, Oncogene.

Post-translational modification of p53 protein in response to ionizing radiation analyzed by mass spectrometry.

P. Thibault, S. Benchimol, J. Abraham, 2000, Journal of molecular biology.

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging

S. Benchimol, H. Vaziri, 1996, Experimental Gerontology.

Transforming activity of mutant human p53 alleles

S. Benchimol, J. Slingerland, Joyce M. Slingerland, 1991, Journal of cellular physiology.

Immortalization of rat embryo fibroblasts by the cellular p53 oncogene.

S. Benchimol, B. Rovinski, Samuel Benchimol, 1988, Oncogene.

Mutation of the p53 gene in human acute myelogenous leukemia.

M. Minden, S. Benchimol, J. Slingerland, 1991, Blood.

The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53.

V. Ling, S. Benchimol, J. Chen, 1993, Oncogene.

Mutator phenotype in Msh2-deficient murine embryonic fibroblasts.

R. Bristow, T. Mak, M. Meuth, 1997, Cancer research.

p53--an examination of sibling support in apoptosis control.

S. Benchimol, 2004, Cancer cell.

Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation

A. Bernstein, S. Benchimol, J. Peacock, 1987, Molecular and cellular biology.

Identification of p53-regulated genes by the method of differential display.

Yunping Lin, S. Benchimol, R. Leng, 2006, Methods in molecular biology.

Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs

P. Iversen, S. Benchimol, Y. Lin, 2012, Oncogene.

Mutation of the p 53 Gene in Human Acute Myelogenous Leukemia

M. Minden, S. Benchimol, J. Slingerland, 2003 .

TRIMming p53 for ubiquitination

S. Benchimol, Elisabeth Tai, 2009, Proceedings of the National Academy of Sciences.

Alterations of p53 and c-myc in the clonal evolution of malignant lymphoma.

M. Minden, S. Benchimol, H. Messner, 1994, Blood.

Multistage Friend erythroleukemia: independent origin of tumor clones with normal or rearranged p53 cellular oncogenes

A. Bernstein, S. Benchimol, Y. Ben-David, 1987, Journal of virology.

Transformation associated p53 protein is encoded by a gene on human chromosome 17

T. Shows, G. Bruns, D. Sheer, 1985, Somatic cell and molecular genetics.

Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein

S. Benchimol, R. Leng, A. Bagashev, 2013, Cell cycle.

Mutation of the p53 gene in human acute myelogenous leukemia.

M. Minden, S. Benchimol, J. Slingerland, 1991, Blood.

GrowthSuppression ofFriend Virus-Transformed Erythroleukemia Cells byp53Protein IsAccompanied by Hemoglobin Production andIsSensitive toErythropoietin

Penny A. Johnson, S. Benchimol, S. Chung, 1993 .

The Fi-gene product of bacteriophage lambda. Purification and properties.

S. Benchimol, A. Becker, 2005, European journal of biochemistry.

The ben gene of bacteriophage λ: Mapping, identification and control of synthesis

S. Benchimol, M. Sumner-Smith, H. Murialdo, 1982 .

Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF ras-transformants-expressing gain of function MTp53

R. Bristow, S. Benchimol, J. Peacock, 2003, Oncogene.

The role of the bacteriophage λ FI gene product during phage head assembly in Vitro

S. Benchimol, H. Murialdo, A. Becker, 1978 .

Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase

S. Benchimol, H. Vaziri, Samuel Benchimol, 1999, Oncogene.

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

S. Benchimol, H. Vaziri, 1998, Current Biology.

ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress.

T. Mak, K. Tsuchihara, Yunping Lin, 2011, Molecular cell.

Radioimmunoassay of the cellular protein p53 in mouse and human cell lines.

D. Pim, S. Benchimol, L. Crawford, 1982, The EMBO journal.

The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy.

R. Bristow, S. Benchimol, R. Hill, 1996, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

ATM‐dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post‐translational activation of p53 protein involving poly(ADP‐ribose) polymerase

T. Davison, C. Arrowsmith, S. Benchimol, 1997, The EMBO journal.

p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.

M. Minden, J. Blondal, S. Benchimol, 1995, Leukemia & lymphoma.

Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

S. Lowe, T. Mak, I. Sarosi, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Role of Pirh2 in Mediating the Regulation of p53 and c-Myc

P. Boutros, I. Jurisica, A. Mes-Masson, 2011, PLoS genetics.

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p 53 protein involving poly ( ADP-ribose ) polymerase block can be overcome upon expression of the SV 40 large

T. Davison, S. Benchimol, H. Vaziri, 2013 .

Analysis of Genomic Integrity and p53-Dependent G1Checkpoint in Telomerase-Induced Extended-Life-Span Human Fibroblasts

G. Nolan, T. Pandita, J. Squire, 1999, Molecular and Cellular Biology.

Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells

S. Benchimol, P. Johnson, M. Mowat, 1991, Molecular and cellular biology.

Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia.

S. Benchimol, M. Bar‐eli, M. Cline, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Introduction of new genetic material into human myeloid leukemic blast stem cells by retroviral infection

S. Benchimol, L. Smith, 1988, Molecular and cellular biology.

Translational regulation of human p53 gene expression.

M. Minden, S. Benchimol, L. Fu, 1996, The EMBO journal.

Abnormal DNA content in oral epithelial dysplasia is associated with increased risk of progression to carcinoma

S. Kamel‐Reid, S. Benchimol, G. Bradley, 2010, British Journal of Cancer.

Structure and functionality of a designed p53 dimer.

T. Davison, C. Arrowsmith, C. Kay, 2001, Journal of molecular biology.

DNA damage- and stress-induced apoptosis occurs independently of PIDD

S. Benchimol, W. Yeh, P. Ohashi, 2009, Apoptosis.

BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence

Weili Ma, S. Benchimol, K. Wheaton, 2010, Aging cell.

The Involvement of MAPK Signaling Pathways in Determining the Cellular Response to p53 Activation

S. Benchimol, Lauren Brown, 2006, Journal of Biological Chemistry.

Regulation of the p53 Response by Cellular Growth and Survival Factors

S. Benchimol, Lauren Brown, 2007 .

Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells

Weili Ma, S. Benchimol, David Miller, 2019, Cell Death & Disease.

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

A. Bernstein, S. Benchimol, M. Mowat, 1985, Nature.

P-glycoprotein and tumor progression.

V. Ling, S. Benchimol, 1994, Journal of the National Cancer Institute.

Expression of the p53 oncogene in acute myeloblastic leukemia

E. McCulloch, S. Benchimol, L. Smith, 1986, The Journal of experimental medicine.

Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene.

D. Pim, G. Matlashewski, S. Benchimol, 1984, The EMBO journal.

Participation of the human p53 3′UTR in translational repression and activation following γ‐irradiation

S. Benchimol, L. Fu, 1997, The EMBO journal.

Phosphorylation of p53 protein in response to ionizing radiation occurs at multiple sites in both normal and DNA-PK deficient cells

S. Benchimol, J. Abraham, D. Spaner, 1999, Oncogene.

P53-transformation-related protein: kinetics of synthesis and accumulation in SV40-infected primary mouse kidney cell cultures.

P. May, S. Benchimol, A. Duthu, 1985, Virology.

EXPRESSION OF THE p 53 ONCOGENE IN ACUTE MYELOBLASTIC LEUKEMIA

E. McCulloch, S. Benchimol, L. Smith, 2022 .

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

L. Salmena, T. Mak, R. Hakem, 2005, Proceedings of the National Academy of Sciences of the United States of America.

P53-mediated radioresistance does not correlate with metastatic potential in tumorigenic rat embryo cell lines following oncogene transfection.

R. Bristow, S. Benchimol, J. Peacock, 1996, International journal of radiation oncology, biology, physics.

Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.

C. Bakal, T. Mak, K. Tsuchihara, 2005, Cancer research.

Ckap 2 Regulates Aneuploidy , Cell Cycling , and Cell Death in a p 53-Dependent Manner

C. Bakal, T. Mak, K. Tsuchihara, 2005 .

A translation repressor element resides in the 3′ untranslated region of human p53 mRNA

Weili Ma, S. Benchimol, L. Fu, 1999, Oncogene.

Inactivation of the Cellular P53 Gene in Friend Virus-Transformed Erythroleukemia Cell Lines

A. Bernstein, S. Benchimol, D. Munroe, 1989 .

Impaired TNFα-induced A20 expression in E1A/Ras-transformed cells

S. Benchimol, C. Mirtsos, W. Yeh, 2009, British Journal of Cancer.

Bacteriophage lambda DNA packaging in vitro. The involvement of the lambda FI gene product, single-strand DNA, and a novel lambda-directed protein in the packaging reaction.

S. Benchimol, A. Becker, H. Lucko, 1982, The Journal of biological chemistry.

Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras.

R. Bristow, S. Benchimol, J. Peacock, 1994, Oncogene.

Proteasome-independent p53 degradation

S. Benchimol, Mais M. Nuaaman, 2013, Cell Research.

Comparative analysis of the involvement of p53, c-myc and c-fos in epidermal growth factor-mediated signal transduction.

S. Benchimol, J. Filmus, R. Buick, 1987, Experimental cell research.

Molecular basis of Pirh2-mediated p53 ubiquitylation

J. Lukin, C. Arrowsmith, A. Lemak, 2008, Nature Structural &Molecular Biology.

Mutation of the endogenous p53 gene in cells transformed by HPV‐16 E7 and EJ c‐ras confers a growth advantage involving an autocrine mechanism.

S. Benchimol, J. Peacock, 1994, The EMBO journal.

Differential utilization of two ATP-generating pathways is regulated by p53.

S. Benchimol, W. Assaily, Wissam Assaily, 2006, Cancer cell.

A novel endonuclease specified by bacteriophage lambda. Purification and properties of the enzyme.

S. Benchimol, A. Becker, H. Lucko, 1982, The Journal of biological chemistry.

The role of p53 in tumor progression.

J. Blondal, S. Benchimol, 1994, Seminars in cancer biology.

Heterogeneity in leukemia cells that escape drug-induced senescence-like state

Benjamin Haibe-Kains, M. Minden, S. Benchimol, 2023, Cell death & disease.

Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells

Weili Ma, S. Benchimol, David Miller, 2019, Cell Death & Disease.

p53-mediated cell cycle arrest and apoptosis.

S. Benchimol, Y. Lin, 1997, Leukemia.

Friend virus induced murine erythroleukaemia: the p53 locus.

S. Benchimol, P. Johnson, 1992, Cancer Surveys.

Molecular Cell Previews HDAC 5 — A Critical Player in the p 53 Acetylation Network

S. Benchimol, S. S. Kim, 2013 .

Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome

Grant W. Brown, Weili Ma, S. Benchimol, 2017, Molecular and Cellular Biology.