R. Broadhurst

发表

Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein.

Daniel Nietlispach, Aaron M Zorn, N. Standart, 2005, Journal of molecular biology.

Solution structures of apo and holo biotinyl domains from acetyl coenzyme A carboxylase of Escherichia coli determined by triple-resonance nuclear magnetic resonance spectroscopy.

T. Morris, M. Howard, R. Broadhurst, 1999, Biochemistry.

Solution Structure of the QUA1 Dimerization Domain of pXqua, the Xenopus Ortholog of Quaking

R. Broadhurst, Muzaffar Ali, 2013, PloS one.

Structure of the Escherichia coli ProQ RNA-binding protein.

A. Bateman, J. Vogel, B. Luisi, 2017, RNA.

Backbone dynamics of oxidised and reduced forms of human atrial natriuretic peptide.

M. Sunde, R. Broadhurst, K. Stott, 2004, Journal of structural biology.

DNA-binding properties of the tandem HMG boxes of high-mobility-group protein 1 (HMG1).

R. Broadhurst, J. O. Thomas, S. Teo, 1998, European journal of biochemistry.

An Approach to the Structure Determination of Larger Proteins Using Triple Resonance NMR Experiments in Conjunction with Random Fractional Deuteration

P. Domaille, J. Ashurst, J. Keeler, 1996 .

Characterization of structural and folding properties of streptokinase by n.m.r. spectroscopy.

C. Dobson, R. Smith, R. Broadhurst, 1993, The Biochemical journal.

Two mutations in the HMG‐box with very different structural consequences provide insights into the nature of binding to four‐way junction DNA.

E. Laue, R. Broadhurst, E. Laue, 1995, The EMBO journal.

Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy.

E. Laue, A. Raine, R. Broadhurst, 1995, Biochemistry.

Interpretation of the polarized electron paramagnetic resonance signal of plant Photosystem I

R. Broadhurst, A. Hoff, P. Hore, 1986 .

Photo-CIDNP of amino acids and proteins: effects of competition for flavin triplets

R. Broadhurst, P. Hore, S. L. Winder, 1995 .

Heteronuclear NMR studies of the specificity of the post‐translational modification of biotinyl domains by biotinyl protein ligase

P. Reche, M. Howard, R. Broadhurst, 2000, FEBS letters.

Three-dimensional structure of the lipoyl domain from the dihydrolipoyl succinyltransferase component of the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli.

M. Howard, R. Broadhurst, E. L. Roberts, 1996, Journal of molecular biology.

SOLUTION STRUCTURE OF HOLO-BIOTINYL DOMAIN FROM ACETYL COENZYME A CARBOXYLASE OF ESCHERICHIA COLI DETERMINED BY TRIPLE-RESONANCE NMR SPECTROSCOPY

T. Morris, M. Howard, R. Broadhurst, 1999 .

Autonomous folding of interdomain regions of a modular polyketide synthase

S. Brewerton, R. N. Miguel, R. Broadhurst, 2007, The FEBS journal.

Interaction between an amantadine analogue and the transmembrane portion of the influenza A M2 protein in liposomes probed by 1H NMR spectroscopy of the ligand.

R. Broadhurst, A. Kolocouris, Raino K Hansen, 2004, Journal of medicinal chemistry.

Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold

R. Broadhurst, L. Moretto, S. Vance, 2019, Scientific Reports.

An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types

S. Teichmann, S. Yokoyama, E. Laue, 1996, Journal of biomolecular NMR.

Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases.

A. Cavalli, R. Broadhurst, K. Weissman, 2010, Chemistry & biology.

DANGLE: A Bayesian inferential method for predicting protein backbone dihedral angles and secondary structure.

Tim J Stevens, Ming-Sin Cheung, T. Stevens, 2010, Journal of magnetic resonance.

Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates† †Electronic supplementary information (ESI) available: Complete experimental details and additional figures. See DOI: 10.1039/c7cc04625a

R. Broadhurst, L. Moretto, S. Vance, 2017, Chemical communications.

Photo-CIDNP of biopolymers

J. Hore, R. Broadhurst, 1993 .

A photochemically induced dynamic nuclear polarization study of denatured states of lysozyme.

C. Dobson, S. Radford, R. Broadhurst, 1991, Biochemistry.

The structure of docking domains in modular polyketide synthases.

Kira J Weissman, Daniel Nietlispach, P. Leadlay, 2003, Chemistry & biology.

Conformational plasticity of ligand-bound and ternary GPCR complexes studied by 19F NMR of the β1-adrenergic receptor

D. Nietlispach, R. Broadhurst, Aditi Tandale, 2020, Nature Communications.

Cis–trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel

Henry A. Lester, Sarah C. R. Lummis, H. Lester, 2005, Nature.

Structure of the chromatin binding (chromo) domain from mouse modifier protein 1

A. Murzin, P. Domaille, E. Laue, 1997, The EMBO journal.

The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer

Brian O. Smith, E. Laue, D. Nietlispach, 2000, The EMBO journal.

Backbone dynamics of the A-domain of HMG1 as studied by 15N NMR spectroscopy.

E. Laue, R. Broadhurst, C. H. Hardman, 1995, Biochemistry.

An RNA degradosome assembly in Caulobacter crescentus

B. Luisi, R. Broadhurst, S. Hardwick, 2010, Nucleic acids research.

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes

B. Luisi, R. Broadhurst, A. Shkumatov, 2017, Nucleic acids research.

1H-NMR assignments and local environments of aromatic residues in bovine, human and guinea pig variants of alpha-lactalbumin.

C. Dobson, J. Baum, R. Broadhurst, 1992, European journal of biochemistry.

Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus

M. Allen, R. Broadhurst, R. Perham, 2004, The FEBS journal.

Hydrogen/deuterium exchange of hydrophobic peptides in model membranes by electrospray ionization mass spectrometry

Isaiah T Arkin, I. Arkin, R. Broadhurst, 2002, Journal of the American Society for Mass Spectrometry.

19F NMR detection of the complex between amantadine and the receptor portion of the influenza A M2 ion channel in DPC micelles.

Christos Zikos, Antonios Kolocouris, R. Broadhurst, 2007, Bioorganic & medicinal chemistry letters.

Three-dimensional structure of the major autoantigen in primary biliary cirrhosis.

M. Howard, R. Broadhurst, R. Perham, 1998, Gastroenterology.

Structure and properties in solution of PsaD, an extrinsic polypeptide of photosystem I.

E D Laue, E. Laue, R. Broadhurst, 1998, European journal of biochemistry.

Multienzyme docking in hybrid megasynthetases.

D. Nietlispach, R. Broadhurst, K. Weissman, 2007, Nature chemical biology.

Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation.

Hui Hong, P. Leadlay, R. Broadhurst, 2016, Chemical communications.

Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis.

A. Raine, R. Broadhurst, R. Perham, 2001, European journal of biochemistry.

Structure and properties of a dimeric N-terminal fragment of human ubiquitin.

R. Broadhurst, K. Stott, P. A. Evans, 2001, Journal of molecular biology.

Equilibrium unfolding studies of horse muscle acylphosphatase.

C. Dobson, N. Taddei, G. Ramponi, 1994, European journal of biochemistry.