J. Dhanjal

发表

Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53Y220C mutant: bioinformatics and experimental evidence

S. Kaul, R. Wadhwa, Navaneethan Radhakrishnan, 2021, Discover Oncology.

Function and structure-based screening of compounds, peptides and proteins to identify drug candidates.

Navaneethan Radhakrishnan, J. Dhanjal, D. Sundar, 2017, Methods.

Molecular modelling studies on flavonoid derivatives as dual site inhibitors of human acetyl cholinesterase using 3D-QSAR, pharmacophore and high throughput screening approaches

J. Dhanjal, C. Tyagi, A. Grover, 2014, Medicinal Chemistry Research.

Fragment based group QSAR and molecular dynamics mechanistic studies on arylthioindole derivatives targeting the α-β interfacial site of human tubulin

J. Dhanjal, C. Tyagi, A. Grover, 2014, BMC Genomics.

Mutant p53L194F Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to MortaparibPlus, a Multimodal Small Molecule Inhibitor

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, Cancers.

Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity

S. Kaul, R. Wadhwa, J. Dhanjal, 2020, Journal of biomolecular structure & dynamics.

Identifying synthetic lethal targets using CRISPR/Cas9 system.

Navaneethan Radhakrishnan, J. Dhanjal, D. Sundar, 2017, Methods.

Computational Structure-Based De Novo Design of Hypothetical Inhibitors against the Anti- Inflammatory Target COX-2

J. Dhanjal, D. Sundar, Khushboo Bafna, 2015, PloS one.

Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers

S. Kaul, R. Wadhwa, J. Dhanjal, 2019, Journal of Experimental & Clinical Cancer Research.

Mechanistic insights into mode of action of a potent natural antagonist of orexin receptor-1 by means of high throughput screening and molecular dynamics simulations.

J. Dhanjal, A. Grover, Sonam Grover, 2014, Combinatorial chemistry & high throughput screening.

Why Ashwagandha for Prevention and Treatment of COVID-19?

S. Kaul, R. Wadhwa, J. Dhanjal, 2020 .

Curcumin-based IKKβ inhibiting anticancer lead design using novel fragment-based group QSAR modelling

J. Dhanjal, N. Bharadvaja, C. Tyagi, 2015, Medicinal Chemistry Research.

Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action

S. Kaul, R. Wadhwa, Navaneethan Radhakrishnan, 2020, Cancers.

A theoretical investigation of DNA dynamics and desolvation kinetics for zinc finger proteinZif268

J. Dhanjal, D. Sundar, S. Dutta, 2015, BMC Genomics.

Identification and Characterization of MortaparibPlus—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, Cancers.

CRISPcut: A novel tool for designing optimal sgRNAs for CRISPR/Cas9 based experiments in human cells.

Navaneethan Radhakrishnan, J. Dhanjal, D. Sundar, 2019, Genomics.

Curcumin-based IKKβ inhibiting anticancer lead design using novel fragment-based group QSAR modelling

J. Dhanjal, N. Bharadvaja, C. Tyagi, 2015, Medicinal Chemistry Research.

Molecular modelling studies on flavonoid derivatives as dual site inhibitors of human acetyl cholinesterase using 3D-QSAR, pharmacophore and high throughput screening approaches

J. Dhanjal, C. Tyagi, A. Grover, 2014, Medicinal Chemistry Research.

Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1

S. Kaul, R. Wadhwa, J. Dhanjal, 2022, Frontiers in Cell and Developmental Biology.

Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells

S. Kaul, R. Wadhwa, J. Dhanjal, 2020, Journal of biomolecular structure & dynamics.

Molecular Characterization and Enhancement of Anticancer Activity of Caffeic Acid Phenethyl Ester by γ Cyclodextrin

S. Kaul, R. Wadhwa, J. Dhanjal, 2016, Journal of Cancer.

Cell Transdifferentiation and Reprogramming in Disease Modeling: Insights into the Neuronal and Cardiac Disease Models and Current Translational Strategies

J. Dhanjal, Birbal Singh, R. Naithani, 2021, Cells.

Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, International Journal of Biological Macromolecules.

Molecular dynamics-based identification of novel natural mortalin–p53 abrogators as anticancer agents

S. Kaul, R. Wadhwa, J. Dhanjal, 2017, Journal of receptor and signal transduction research.

Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence

S. Kaul, R. Wadhwa, Navaneethan Radhakrishnan, 2019, Marine drugs.

Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence

Yue Yu, S. Kaul, R. Wadhwa, 2019, Journal of experimental & clinical cancer research : CR.

Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia

J. Dhanjal, D. Sundar, Gurvinder Kaur, 2017, Clinical Epigenetics.

A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms

S. Kaul, R. Wadhwa, J. Dhanjal, 2022, Cancers.

Administration of inhibitors targeting topoisomerase II increases the chances of acute myelogenous

J. Dhanjal, Asmita Das, 2015 .

Computational Protein Engineering Approaches for Effective Design of New Molecules

Jaspreet Kaur Dhanjal, Durai Sundar, Anjani Kumari, 2019, Encyclopedia of Bioinformatics and Computational Biology.

Fragment based group QSAR and molecular dynamics mechanistic studies on arylthioindole derivatives targeting the α-β interfacial site of human tubulin

J. Dhanjal, C. Tyagi, A. Grover, 2014, BMC Genomics.

COVID-19, Neuropathology, and Aging: SARS-CoV-2 Neurological Infection, Mechanism, and Associated Complications

Vishal C. Kalel, J. Dhanjal, R. Kandimalla, 2021, Frontiers in Aging Neuroscience.

Mixed Inhibition of cPEPCK by Genistein, Using an Extended Binding Site Located Adjacent to Its Catalytic Cleft

J. Dhanjal, D. Sundar, Arpit Jain, 2015, PloS one.

Embelin inhibits TNF-α converting enzyme and cancer cell metastasis: molecular dynamics and experimental evidence

S. Kaul, R. Wadhwa, J. Dhanjal, 2014, BMC Cancer.

Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

Arun Prakash Upadhyay, J. Dhanjal, R. Kandimalla, 2022, Genes & diseases.

Use of ligand-based pharmacophore modeling and docking approach to find novel acetylcholinesterase inhibitors for treating Alzheimer's.

J. Dhanjal, A. Grover, Asmita Das, 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Computational and in vitro experimental analyses of the Anti-COVID-19 potential of Mortaparib and MortaparibPlus.

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, Bioscience reports.

Mechanistic insights into mode of action of novel natural cathepsin L inhibitors

J. Dhanjal, C. Tyagi, A. Grover, 2013, BMC Genomics.

Bioinformatics and Molecular Insights to Anti-Metastasis Activity of Triethylene Glycol Derivatives

S. Kaul, R. Wadhwa, J. Dhanjal, 2020, International journal of molecular sciences.

Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus

Sukriti Goyal, Abhinav Grover, Sonam Grover, 2014, BMC Bioinformatics.

Novel Natural Structure Corrector of ApoE4 for Checking Alzheimer's Disease: Benefits from High Throughput Screening and Molecular Dynamics Simulations

J. Dhanjal, C. Tyagi, A. Grover, 2013, BioMed research international.

Development of Dual Inhibitors against Alzheimer's Disease Using Fragment-Based QSAR and Molecular Docking

Sukriti Goyal, Abhinav Grover, Jaspreet Kaur Dhanjal, 2014, BioMed research international.

Evaluation of off-targets predicted by sgRNA design tools.

J. Dhanjal, D. Sundar, Shreya C. Pal, 2020, Genomics.

Quantitative Structure-Activity Relationship (QSAR): Modeling Approaches to Biological Applications

Jaspreet Kaur Dhanjal, Durai Sundar, Mannu Jayakanthan, 2019, Encyclopedia of Bioinformatics and Computational Biology.

Computational design of novel flavonoid analogues as potential AChE inhibitors: analysis using group-based QSAR, molecular docking and molecular dynamics simulations

Sukriti Goyal, Abhinav Grover, Jaspreet Kaur Dhanjal, 2015, Structural Chemistry.

Group-based QSAR and molecular dynamics mechanistic analysis revealing the mode of action of novel piperidinone derived protein-protein inhibitors of p53-MDM2.

Sukriti Goyal, Abhinav Grover, Sonam Grover, 2014, Journal of molecular graphics & modelling.

Mechanistic insights into mode of actions of novel oligopeptidase B inhibitors for combating leishmaniasis

Sukriti Goyal, Abhinav Grover, Sonam Grover, 2014, Journal of Molecular Modeling.

Mechanistic insights into mode of action of potent natural antagonists of BACE-1 for checking Alzheimer's plaque pathology.

J. Dhanjal, R. Hamid, A. Grover, 2014, Biochemical and biophysical research communications.

Computational Approaches for Designing Highly Specific and Efficient sgRNAs.

Navaneethan Radhakrishnan, J. Dhanjal, D. Sundar, 2021, Methods in molecular biology.

Computational and in vitro experimental analyses of the anti-COVID-19 potential of Mortaparib and MortaparibPlus

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, Bioscience reports.

Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia

J. Dhanjal, D. Sundar, L. Kumar, 2017, Clinical Epigenetics.

COVID19-inhibitory activity of withanolides involves targeting of the host cell surface receptor ACE2: insights from computational and biochemical assays

S. Kaul, R. Wadhwa, J. Dhanjal, 2021, Journal of biomolecular structure & dynamics.

A monoclonal antibody against annexin A2 targets stem and progenitor cell fractions in tumors

Swapnil C. Kamble, J. Dhanjal, S. Bapat, 2021, Translational oncology.

Engineering of Cas9 for improved functionality

J. Dhanjal, D. Sundar, D. Vora, 2020 .

Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors

Abhinav Grover, Sonam Grover, Jaspreet Kaur Dhanjal, 2014, BMC Genomics.

Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence

Yue Yu, S. Kaul, R. Wadhwa, 2019, Journal of Experimental & Clinical Cancer Research.

Group-based QSAR and molecular dynamics mechanistic analysis revealing the mode of action of novel piperidinone derived protein-protein inhibitors of p53-MDM2.

J. Dhanjal, C. Tyagi, A. Grover, 2014, Journal of Molecular Graphics and Modelling.

Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility

J. Dhanjal, N. Bharadvaja, A. Grover, 2015, BMC Genomics.

Novel Fragment‐Based QSAR Modeling and Combinatorial Design of Pyrazole‐Derived CRK3 Inhibitors as Potent Antileishmanials

Sukriti Goyal, Abhinav Grover, Chetna Tyagi, 2014, Chemical biology & drug design.

Resisting resistant Mycobacterium tuberculosis naturally: mechanistic insights into the inhibition of the parasite's sole signal peptidase Leader peptidase B.

Heena Dhiman, J. Dhanjal, A. Grover, 2013, Biochemical and biophysical research communications.

TCR-ESM: employing protein language embeddings to predict TCR-peptide-MHC binding

J. Dhanjal, D. Sundar, Shashank Yadav, 2023, Computational and Structural Biotechnology Journal.

Identifying synthetic lethal targets using CRISPR/Cas9 system.

Navaneethan Radhakrishnan, J. Dhanjal, D. Sundar, 2017, Methods.

Mechanistic insights into mode of action of novel natural cathepsin L inhibitors

J. Dhanjal, C. Tyagi, A. Grover, 2013, BMC Genomics.