A. Wilmes

发表

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Paul Jennings, Alice Limonciel, Bob van de Water, 2018, Archives of Toxicology.

Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.

Bas J Blaauboer, Christian G Huber, Paul Jennings, 2013, Journal of proteomics.

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes.

Paul Jennings, Alice Limonciel, Anja Wilmes, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

A. Kopp-Schneider, F. Bois, B. van de Water, 2018, Front. Genet..

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.

Annette Kopp-Schneider, Paul Jennings, Alice Limonciel, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study.

Annette Kopp-Schneider, Paul Jennings, Alice Limonciel, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.

Paul Jennings, Alice Limonciel, Anja Wilmes, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Interleukin-19 as a translational indicator of renal injury

Paul Jennings, Alice Limonciel, Anja Wilmes, 2014, Archives of Toxicology.

Renal Cell Culture

A. Wilmes, P. Jennings, G. Gstraunthaler, 2014 .

Translational Biomarkers, In Vitro and In Vivo

A. Limonciel, A. Wilmes, P. Jennings, 2014 .

Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel.

A. Limonciel, A. Wilmes, P. Jennings, 2014, Toxicology and applied pharmacology.

Nrf2 inducibility of aldo-keto reductases.

A. Wilmes, P. Jennings, M. Leonard, 2013, Toxicology letters.

Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity.

Paul Jennings, Anja Wilmes, Walter Pfaller, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells

J. Miller, A. Wilmes, P. Northcote, 2011, Investigational New Drugs.

A Protocol for One-Step Differentiation of Human Induced Pluripotent Stem Cells into Mature Podocytes.

A. Wilmes, P. Jennings, G. Gstraunthaler, 2019, Methods in molecular biology.

Ross River virus: molecular and cellular aspects of disease pathogenesis.

M. Heise, K. Gilmore, A. Wilmes, 2005, Pharmacology & therapeutics.

Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae.

D. Bellows, R. Heathcott, J. Miller, 2012, Gene.

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

Alice Krebs, Barbara M. A. van Vugt-Lussenburg, Tanja Waldmann, 2020, Archives of Toxicology.

Preclinical Development Peloruside-and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have b I-Tubulin Mutations and Altered Expression of b II-and b III-Tubulin Isotypes

J. Miller, A. Wilmes, P. Giannakakou, 2011 .

Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes

J. Miller, A. Wilmes, P. Giannakakou, 2011, Molecular Cancer Therapeutics.

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells

J. Miller, A. Wilmes, P. Northcote, 2011, Cancer Chemotherapy and Pharmacology.

Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells

Paul Jennings, Alice Limonciel, Anja Wilmes, 2012, Archives of Toxicology.

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

E. Lock, H. Ellinger-Ziegelbauer, A. Limonciel, 2011, Archives of Toxicology.

Paclitaxel effects on the proteome of HL-60 promyelocytic leukemic cells: comparison to peloruside A

J. Miller, A. Wilmes, P. Rawson, 2012, Investigational New Drugs.

Comparison of human recombinant protein coatings and fibroblast-ECM to Matrigel for induced pluripotent stem cell culture and renal podocyte differentiation.

A. Wilmes, R. Kluin, C. Murphy, 2022, ALTEX.

Interleukin-19 as a translational indicator of renal injury

A. Limonciel, A. Wilmes, P. Jennings, 2014, Archives of Toxicology.

Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood-brain barrier.

D. Weiss, W. Dekant, A. Wilmes, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Dyrk, a Dual Specificity Protein Kinase with Unique Structural Features Whose Activity Is Dependent on Tyrosine Residues between Subdomains VII and VIII (*)

A. Schürmann, A. Wilmes, H. Joost, 1996, The Journal of Biological Chemistry.

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

E. Lock, H. Ellinger-Ziegelbauer, A. Limonciel, 2012, Archives of Toxicology.

Structure-activity studies of the pelorusides: new congeners and semi-synthetic analogues.

J. Goodman, J. Miller, A. Wilmes, 2011, Organic & biomolecular chemistry.

The bile acid deoxycholic acid ( DCA ) at neutral pH activates NFB and induces IL-8 expression in oesophageal cells in vitro . Carcinogenesis

J. Baxter, J. Parry, A. Wilmes, 2014 .

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro.

G. Jenkins, J. Baxter, J. Parry, 2003, Carcinogenesis.

The Use of Renal Cell Culture for Nephrotoxicity Investigations

A. Wilmes, P. Jennings, 2014 .

Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening

A. Wilmes, P. Jennings, C. Rauch, 2014 .

Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages

Sylvia E. Le Dévédec, M. J. Moné, C. Verfaillie, 2021, Archives of Toxicology.

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

Gregory D. Tredwell, J. Kleinjans, A. Kopp-Schneider, 2018, Front. Genet..

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

P. Shepard, M. Vinken, B. Seligmann, 2018, Archives of Toxicology.

Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics.

Stephan Aiche, Theresa Kristl, Christian G Huber, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Delineation of the Key Aspects in the Regulation of Epithelial Monolayer Formation

Paul Jennings, Alice Limonciel, Anja Wilmes, 2013, Molecular and Cellular Biology.

Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.

G. Myatt, M. Ingelman-Sundberg, A. Wilmes, 2016, Advances in experimental medicine and biology.

The Molecular and Cellular Aspects of Arthritis Due to Alphavirus Infections

A. Wilmes, S. Mahalingam, Nestor E. Rulli, 2007, Annals of the New York Academy of Sciences.

Temporal transcriptomic alterations of cadmium exposed human iPSC-derived renal proximal tubule-like cells.

Thomas E. Exner, A. Wilmes, P. Jennings, 2021, Toxicology in vitro : an international journal published in association with BIBRA.

Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

J. Kleinjans, G. Carta, A. Wilmes, 2021, Scientific Reports.

Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems.

S. O. Mueller, A. Guillouzo, W. Dekant, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

M. Lako, G. Carta, A. Wilmes, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline*

Oliver Kohlbacher, Christian G Huber, Paul Jennings, 2015, The Journal of Biological Chemistry.

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

Thomas E. Exner, Andrea Paola Cediel Ulloa, Ugis Sarkans, 2020, Archives of Toxicology.

Two-Stage Model-Free Tests of Synergy in Drug Combinations

T. Kawashima, J. Miller, A. Wilmes, 2012, Journal of biopharmaceutical statistics.

Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.

J. Miller, A. Wilmes, P. Northcote, 2007, Molecular pharmaceutics.

Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity.

Arun K. Ghosh, Xiaoming Xu, J. Miller, 2010, The Journal of organic chemistry.

Human liver cell cultivation in a miniaturised 3 D bioreactor system for in vitro studies on hepatic drug toxicity

C. Guillou, T. Andersson, C. Huber, 2022 .

Differentiation of human iPSCs into functional podocytes

Paul Jennings, Anja Wilmes, Florian Meier, 2018, PloS one.

An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.

Thomas E. Exner, C. Verfaillie, A. Wilmes, 2022, Toxicology in vitro : an international journal published in association with BIBRA.

Differentiation and Subculturing of Renal Proximal Tubular‐like Cells Derived from Human iPSC

A. Wilmes, P. Jennings, E. Naderlinger, 2023, Current protocols.

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells

Thomas E. Exner, G. Carta, A. Wilmes, 2022, Cell Biology and Toxicology.

Delineation of the Key Aspects in the Regulation of Epithelial Monolayer Formation

A. Limonciel, A. Wilmes, P. Jennings, 2013, Molecular and Cellular Biology.

Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel.

A. Limonciel, A. Wilmes, P. Jennings, 2014, Toxicology and applied pharmacology.

Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes

J. Miller, A. Wilmes, P. Giannakakou, 2011, Molecular Cancer Therapeutics.

Transcriptomic profile of human iPSC-derived podocyte-like cells exposed to a panel of xenobiotics.

A. Wilmes, C. Murphy, Paul Jennings, 2024, Toxicology in vitro : an international journal published in association with BIBRA.