J. Stommel

发表

Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response.

D. Levens, Eric Batchelor, Julia C. Liu, 2017, Molecular cell.

A leucine‐rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

G. Wahl, T. Hope, G. Jimenez, 1999, The EMBO journal.

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

G. Wahl, G. Jimenez, J. Stommel, 2000, Nature Genetics.

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

G. Wahl, G. Jimenez, J. Stommel, 1999, Oncogene.

Malignant astrocytic glioma: genetics, biology, and paths to treatment.

L. Chin, W. Hahn, C. Brennan, 2007, Genes & development.

Hdmx Modulates the Outcome of P53 Activation in Human Tumor Cells*

Mengjia Tang, G. Wahl, J. Stommel, 2006, Journal of Biological Chemistry.

P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

Gerald C. Chu, L. Chin, C. Brennan, 2008, Nature.

Pancreatic cancers require autophagy for tumor growth.

Marc Liesa, Josef Mautner, Haoqiang Ying, 2011, Genes & development.

Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies

Keith L. Ligon, James E. Bradner, Lynda Chin, 2007, Science.

An Integrated Clinical, Omic, and Image Atlas of an Evolving Metastatic Breast Cancer

Laura M. Heiser, Erik A. Burlingame, P. Spellman, 2020 .

Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example

C. N. Coleman, E. Petricoin, L. Liotta, 2017, Molecular Cancer Therapeutics.

The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans.

D. Carrasco, M. Protopopova, K. Sukhdeo, 2006, Cancer cell.

Cholesterol Metabolism: A Potential Therapeutic Target in Glioblastoma

J. Stommel, Qian Sun, F. Ahmad, 2019, Cancers.

treatmentastrocytic glioma: genetics, biology, and paths to

L. Chin, W. Hahn, C. Brennan, 2008 .

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.

Gerald C. Chu, Wing Hong Wong, L. Chin, 2008, Cold Spring Harbor symposia on quantitative biology.

Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma

Carlos A. Tristan, U. Shankavaram, Eric Batchelor, 2017, OncoTarget.

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

L. Chin, Yonghong Xiao, C. Brennan, 2010, Proceedings of the National Academy of Sciences.

Accelerated MDM2 auto‐degradation induced by DNA‐damage kinases is required for p53 activation

G. Wahl, J. Stommel, Geoffrey M Wahl, 2004, The EMBO journal.

A New Twist in the Feedback Loop: Stress-Activated MDM2 Destabilization is Required for p53 Activation

G. Wahl, J. Stommel, 2005, Cell cycle.

Extra Views A New Twist in the Feedback Loop Stress-Activated MDM 2 Destabilization is Required for p 53 Activation

G. Wahl, J. Stommel, 2005 .

v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1.

P. Farnham, J. Stommel, M. Cornwell, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

P 53 and Pten control neural and glioma stem / progenitor cell renewal and differentiation

Chin, Gerald C. Chu, C. Brennan, 2014 .

Gatekeepers of the Guardian: p53 Regulation by Post-Translational Modification, MDM2 and MDMX

G. Wahl, J. Stommel, M. Wade, 2007 .

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

S. Gygi, W. Kaelin, J. Harper, 2010, Cancer cell.

CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level

Ji Luo, Eric Batchelor, Eric Batchelor, 2017, Nucleic acids research.

Targeting EGFR Induced Oxidative Stress by PARP1 Inhibition in Glioblastoma Therapy

L. Chin, K. Hoadley, R. DePinho, 2010, PloS one.

An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer

Laura M. Heiser, Erik A. Burlingame, P. Spellman, 2020, bioRxiv.

LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1

K. Camphausen, D. Kambach, J. Stommel, 2019, Scientific Reports.

Malignant astrocytic glioma : genetics , biology , and paths to treatment

W. Cavenee, F. Furnari, J. Stommel, 2007 .

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.

Gerald C. Chu, Wing Hong Wong, L. Chin, 2008, Cold Spring Harbor symposia on quantitative biology.

Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example

E. Petricoin, L. Liotta, J. Stommel, 2017, Molecular Cancer Therapeutics.

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

S. Gygi, W. Kaelin, J. Harper, 2010, Cancer cell.

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

Laura M. Heiser, Erik A. Burlingame, P. Spellman, 2022, Cell reports. Medicine.