Y. Bian

发表

TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB c-REL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer

Joshua M. Stuart, P. Meltzer, W. Xiao, 2016, Oncogene.

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

Jason B. White, M. Ferrer, Noel Southall, 2020, Science Translational Medicine.

Inhibition of mTOR Reduces Anal Carcinogenesis in Transgenic Mouse Model

A. Kulkarni, Y. Bian, B. Hall, 2013, PloS one.

Detecting low-abundance p16 and p53 mutations in pancreatic juice using a novel assay: Heteroduplex analysis of limiting dilution PCRs

M. Goggins, M. Canto, Y. Bian, 2006, Cancer biology & therapy.

Progressive Tumor Formation in Mice with Conditional Deletion of TGF- B Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway Molecular Biology, Pathobiology, and

L. Wakefield, K. Flanders, A. Kulkarni, 2009 .

Targeting of interleukin-13 receptor α2 for treatment of head and neck squamous cell carcinoma induced by conditional deletion of TGF-β and PTEN signaling

R. Puri, A. Kulkarni, Y. Bian, 2013, Journal of Translational Medicine.

Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis

Nie, Xiaobo, Y. Bian, 2016, OncoTargets and therapy.

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

K. Nagashima, M. Ferrer, A. Shilatifard, 2018, Science Translational Medicine.

Epidermal overexpression of transgenic ΔNp63 promotes type 2 immune and myeloid inflammatory responses and hyperplasia via NF‐κB activation

C. Van Waes, S. Sinha, A. Mattox, 2014, The Journal of pathology.

ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation.

C. Van Waes, S. Sinha, Zhong Chen, 2011, Cancer research.

Tumor and Stem Cell Biology D Np 63 Versatilely Regulates a Broad NFk B Gene Program and Promotes Squamous Epithelial Proliferation , Migration , and Inflammation

S. Sinha, C. Waes, Zhong Chen, 2011 .

Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis

Y. Bian, Hong Yuan, Wei-Dong Chen, 2016, OncoTargets and therapy.

Cancer Therapy : Preclinical Chemopreventive and Chemotherapeutic Actions of mTOR Inhibitor in Genetically De fi ned Head and Neck Squamous Cell Carcinoma Mouse Model

A. Kulkarni, Y. Bian, J. Gutkind, 2012 .

CK2 Phosphorylates and Inhibits TAp73 Tumor Suppressor Function to Promote Expression of Cancer Stem Cell Genes and Phenotype in Head and Neck Cancer

C. Van Waes, Zhong Chen, Hai Lu, 2014, Neoplasia.

Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development.

B. Pasche, C. Weghorst, Y. Bian, 2007, Human molecular genetics.

Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation

A. Kulkarni, C. Waes, Y. Bian, 2012, Oncogene.

PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer

James B. Mitchell, A. Kulkarni, C. Van Waes, 2013, Clinical Cancer Research.

TGF-β Signaling Alterations in Cancer

B. Pasche, Y. Bian, V. Kaklamani, 2004 .

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

Christian Freudlsperger, C. Van Waes, Zhong Chen, 2012, Oncogene.

Somatic acquisition and signaling of TGFBR1*6A in cancer.

G. von Heijne, Chiang-Ching Huang, W. Frankel, 2005, JAMA.

TGFBR1*6A may contribute to hereditary colorectal cancer.

A. de la Chapelle, B. Pasche, J. Baron, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.

L. Wakefield, K. Flanders, A. Kulkarni, 2009, Cancer research.

TGFβ Receptor I Conditional Knockout Mice Develop Spontaneous Squamous Cell Carcinoma

R. Puri, A. Kulkarni, S. Karlsson, 2007, Cell cycle.

Chemopreventive and Chemotherapeutic Actions of mTOR Inhibitor in Genetically Defined Head and Neck Squamous Cell Carcinoma Mouse Model

A. Kulkarni, Y. Bian, J. Gutkind, 2012, Clinical Cancer Research.

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

L. Dang, C. Van Waes, Zhong Chen, 2013, Oncogene.

Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell–Like Phenotype

M. Ferrer, P. Shinn, R. Guha, 2019, Molecular Cancer Therapeutics.

MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma.

A. Kulkarni, Y. Bian, Zhi‐Jun Sun, 2013, Cancer letters.

Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer

M. Ferrer, B. Gryder, Y. Bian, 2017, Journal of Translational Medicine.

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

R. Hruban, J. Eshleman, M. Goggins, 2008, Cancer biology & therapy.

Selective blockade of B7‐H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma

A. Kulkarni, Y. Bian, Lei Wu, 2017, Journal of cellular and molecular medicine.

MEK Inhibitor PD-0325901 Overcomes Resistance to CK2 Inhibitor CX-4945 and Exhibits Anti-Tumor Activity in Head and Neck Cancer

Zhong Chen, Y. Bian, J. Friedman, 2015, International journal of biological sciences.