Jiann-Ruey Hong

发表

GSIV serine/threonine kinase can induce apoptotic cell death via p53 and pro-apoptotic gene Bax upregulation in fish cells

Latif Reshi, Horng-Cherng Wu, Jen-Leih Wu, 2016, Apoptosis.

Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish

Jen-Leih Wu, Jiann-Ruey Hong, Jo-Chi Hung, 2021, International journal of molecular sciences.

Identification of Aquatic Birnavirus VP3 Death Domain and Its Dynamic Interaction Profiles in Early and Middle Replication Stages in Fish Cells

Jen-Leih Wu, Jiann-Ruey Hong, 2012 .

Aquatic birnavirus capsid protein, VP3, induces apoptosis via the Bad-mediated mitochondria pathway in fish and mouse cells

Jen-Leih Wu, Jiann-Ruey Hong, Chien-Li Chiu, 2010, Apoptosis.

IPNV VP5, a novel anti-apoptosis gene of the Bcl-2 family, regulates Mcl-1 and viral protein expression.

Jen-Leih Wu, Jiann-Ruey Hong, H. Gong, 2002, Virology.

Liver‐specific expression of p53‐negative regulator mdm2 leads to growth retardation and fragile liver in zebrafish

Y. Liou, Jen-Leih Wu, Jiann-Ruey Hong, 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

Betanodavirus: Mitochondrial disruption and necrotic cell death.

Jiann-Ruey Hong, 2013, World journal of virology.

Stage-Specific Expression of TNFα Regulates Bad/Bid-Mediated Apoptosis and RIP1/ROS-Mediated Secondary Necrosis in Birnavirus-Infected Fish Cells

Jen-Leih Wu, Jiann-Ruey Hong, Ching-Chun Lin, 2011, PloS one.

Inducible Male Infertility by Targeted Cell Ablation in Zebrafish Testis

Jen-Leih Wu, Jiann-Ruey Hong, G. Her, 2010, Marine Biotechnology.

Infectious Spleen and Kidney Necrosis Virus (ISKNV) Triggers Mitochondria-Mediated Dynamic Interaction Signals via an Imbalance of Bax/Bak over Bcl-2/Bcl-xL in Fish Cells

Jen-Leih Wu, Jiann-Ruey Hong, Pin-Han Chen, 2022, Viruses.

EPA and DHA can modulate cell death via inhibition of the Fas/tBid-mediated signaling pathway with ISKNV infection in grouper fin cell line (GF-1) cells.

Jen-Leih Wu, Jiann-Ruey Hong, H. Chiu, 2020, Fish & shellfish immunology.

Modulation of Mitochondria During Viral Infections Modulation of Mitochondria During Viral Infections

Latif Reshi, Hao-Ven Wang, Jiann-Ruey Hong, 2018 .

Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development

Jen-Leih Wu, Jiann-Ruey Hong, Jo-Chi Hung, 2016, Journal of Biomedical Science.

Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish

Jen-Leih Wu, Jiann-Ruey Hong, Cliff Ji-Fan Lin, 2004, Development.

The Role of PSR in Zebrafish (Danio rerio) at Early Embryonic Development

Jen-Leih Wu, Jiann-Ruey Hong, Wan-Lun Taung, 2018, Recent Advances in Zebrafish Researches.

Increase of hepatic fat accumulation by liver specific expression of Hepatitis B virus X protein in zebrafish.

Jiann-Ruey Hong, G. Her, Chia-Chun Hsu, 2010, Biochimica et biophysica acta.

Activation of cytokine expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus-infected cells.

Jen-Leih Wu, Jiann-Ruey Hong, Ching-Chun Lin, 2011, Fish & shellfish immunology.

Infectious pancreatic necrosis virus induces apoptosis in vitro and in vivo independent of VP5 expression.

Jen-Leih Wu, Jiann-Ruey Hong, H. Sindre, 2005, Virology.

Induction of apoptosis and secondary necrosis by infectious pancreatic necrosis virus in fish embryonic cells

Jen-Leih Wu, Jiann-Ruey Hong, Tai-Lang Lin, 1998 .

Imbalance in liver homeostasis leading to hyperplasia by overexpressing either one of the Bcl‐2‐related genes, zfBLP1 and zfMcl‐1a

Jen-Leih Wu, Jiann-Ruey Hong, G. Her, 2006, Developmental dynamics : an official publication of the American Association of Anatomists.

Infectious spleen and kidney necrosis virus induces the reactive oxidative species/Nrf2-mediated oxidative stress response for the regulation of mitochondrion-mediated Bax/Bak cell death signals in GF-1 cells

Jiann-Ruey Hong, Pin-Han Chen, Tsai-Ching Hsueh, 2022, Frontiers in Microbiology.

Induction and molecular regulation of host cell apoptosis by infectious pancreatic necrosis virus infection

Jen-Leih Wu, Jiann-Ruey Hong, 2003 .

Aquatic viruses induce host cell death pathways and its application.

Latif Reshi, Jen-Leih Wu, Hao-Ven Wang, 2016, Virus research.

RNA Viruses: ROS-Mediated Cell Death

Jiann-Ruey Hong, Yi‐Che Su, M. L. Reshi, 2014, International journal of cell biology.

Aquatic Birnavirus-Induced ER Stress-Mediated Death Signaling Contribute to Downregulation of Bcl-2 Family Proteins in Salmon Embryo Cells

Jen-Leih Wu, Jiann-Ruey Hong, Mark Hung‐Chih Chen, 2011, PloS one.

Overexpression of Bcl2 and Bcl2L1 Can Suppress Betanodavirus-Induced Type III Cell Death and Autophagy Induction in GF-1 Cells

Jiann-Ruey Hong, H. Liao, Ang-Jung Lee, 2022, Symmetry.

Anti-Bcl-2 family members, zfBcl-xL and zfMcl-1a, prevent cytochrome c release from cells undergoing betanodavirus-induced secondary necrotic cell death

Jen-Leih Wu, Jiann-Ruey Hong, Shi-ping Chen, 2007, Apoptosis.

Dynamics of Nontypical Apoptotic Morphological Changes Visualized by Green Fluorescent Protein in Living Cells with Infectious Pancreatic Necrosis Virus Infection

Jen-Leih Wu, Jiann-Ruey Hong, Jer-Yen Yang, 1999, Journal of Virology.

RNA interference technology used for the study of aquatic virus infections.

Jen-Leih Wu, Hao-Ven Wang, Jiann-Ruey Hong, 2014, Fish & shellfish immunology.

Mitochondria as a Favourite Organelle for Invading Viruses

Latif Reshi, Jiann-Ruey Hong, 2016 .

Betanodavirus non-structural protein B2: A novel necrotic death factor that induces mitochondria-mediated cell death in fish cells.

Jen-Leih Wu, Jiann-Ruey Hong, Yu-Chin Su, 2009, Virology.

A Mitochondrion-Targeting Protein (B2) Primes ROS/Nrf2-Mediated Stress Signals, Triggering Apoptosis and Necroptosis in Lung Cancer

Jiann-Ruey Hong, S. Hung, H. Chiu, 2023, Biomedicines.

Betanodavirus B2 protein triggers apoptosis and necroptosis in lung cancer cells that suppresses autophagy

Jiann-Ruey Hong, Yu-Chin Su, H. Chiu, 2017, Oncotarget.

Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting

Jiann-Ruey Hong, Jo-Chi Hung, H. Chiu, 2014, Apoptosis.

Betanodavirus Induces Oxidative Stress-Mediated Cell Death That Prevented by Anti-Oxidants and Zfcatalase in Fish Cells

Jiann-Ruey Hong, G. Her, Yu-Chin Su, 2011, PloS one.

RGNNV induces mitochondria-mediated cell death via newly synthesized protein dependent pathway in fish cells.

Horng-Cherng Wu, Jen-Leih Wu, Jiann-Ruey Hong, 2010, Fish & shellfish immunology.

Betanodavirus non-structural protein B1: A novel anti-necrotic death factor that modulates cell death in early replication cycle in fish cells.

Jiann-Ruey Hong, Yu-Chin Su, Lei-Jia Chen, 2009, Virology.

The Proapoptotic Gene Bad Regulates Brain Development via p53-Mediated Stress Signals in Zebrafish

Jen-Leih Wu, Jiann-Ruey Hong, Jo-Chi Hung, 2021, Cells.

Zebrafish anti-apoptotic gene Bcl-xL can prevent aquatic birnavirus-induced cell death in fish cells without affecting expression of viral proteins.

Jen-Leih Wu, Jiann-Ruey Hong, Ming-Chyuan Chen, 2011, Fish & shellfish immunology.

Anti‐apoptotic genes Bcl‐2 and Bcl‐xL overexpression can block iridovirus serine/threonine kinase‐induced Bax/mitochondria‐mediated cell death in GF‐1 cells

Latif Reshi, Jiann-Ruey Hong, C. Hui, 2017, Fish & shellfish immunology.

Interferon Regulatory Factor-1 (IRF-1) Is Involved in the Induction of Phosphatidylserine Receptor (PSR) in Response to dsRNA Virus Infection and Contributes to Apoptotic Cell Clearance in CHSE-214 Cell

Jen-Leih Wu, Jiann-Ruey Hong, Ø. Evensen, 2014, International journal of molecular sciences.

Chapter 17 Modulation of Mitochondria During Viral Infections

Latif Reshi, Hao-Ven Wang, Jiann-Ruey Hong, 2019 .

Modulation of Mitochondria During Viral Infections

Latif Reshi, Hao-Ven Wang, Jiann-Ruey Hong, 2018, Mitochondrial Diseases.

Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development

Jen-Leih Wu, Jiann-Ruey Hong, Jo-Chi Hung, 2016, Journal of Biomedical Science.

Betanodavirus B2 Causes ATP Depletion-induced Cell Death via Mitochondrial Targeting and Complex II Inhibition in Vitro and in Vivo*

Jiann-Ruey Hong, Yu-Chin Su, 2010, The Journal of Biological Chemistry.

Aquatic birnavirus induces necrotic cell death via the mitochondria-mediated caspase pathway.

Jen-Leih Wu, Jiann-Ruey Hong, G. Her, 2010, Fish & shellfish immunology.

Nuclear targeting of the betanodavirus B1 protein via two arginine-rich domains induces G1/S cell cycle arrest mediated by upregulation of p53/p21

Latif Reshi, Jiann-Ruey Hong, Yu-Chin Su, 2018, Scientific Reports.

Giant seaperch iridovirus (GSIV) induces mitochondria-mediated cell death that is suppressed by bongkrekic acid and cycloheximide in a fish cell line.

Jen-Leih Wu, Jiann-Ruey Hong, C. Wen, 2016, Virus research.

Betanodavirus up-regulates chaperone GRP78 via ER stress: roles of GRP78 in viral replication and host mitochondria-mediated cell death

Jen-Leih Wu, Jiann-Ruey Hong, Yu-Chin Su, 2011, Apoptosis.

Giant seaperch iridovirus infection upregulates Bas and Bak expression, leading to apoptotic death of fish cells.

Jen-Leih Wu, Jiann-Ruey Hong, C. Hui, 2015, Fish & shellfish immunology.

Zebrafish anti-apoptotic protein zfBcl-xL can block betanodavirus protein alpha-induced mitochondria-mediated secondary necrosis cell death.

Horng-Cherng Wu, Jen-Leih Wu, Jiann-Ruey Hong, 2008, Fish & shellfish immunology.

Betanodavirus induces phosphatidylserine exposure and loss of mitochondrial membrane potential in secondary necrotic cells, both of which are blocked by bongkrekic acid.

Jen-Leih Wu, Jiann-Ruey Hong, G. Her, 2006, Virology.

Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio).

Jiann-Ruey Hong, G. Her, C. Lai, 2011, Biochimica et biophysica acta.

Complete genome sequence and phylogenetic analysis of megalocytivirus RSIV-Ku: A natural recombination infectious spleen and kidney necrosis virus

Jiann-Ruey Hong, C. Wen, C. Ku, 2017, Archives of Virology.

Nodaviruses of Fish

S. Chi, Jiann-Ruey Hong, Y-C Wu, 2016 .