Xian-hui He

H. Pan, D. Ouyang, Xian-hui He, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages

C. Zhang, D. Ouyang, Xian-hui He, 2019, Apoptosis.

Baicalin inhibits necroptosis by decreasing oligomerization of phosphorylated MLKL and mitigates caerulein-induced acute pancreatitis in mice.

D. Ouyang, Xian-hui He, Li-hui Xu, 2022, International immunopharmacology.

Phenotypic and Functional Analysis of LCMV gp 33-41-Specific CD 8 T Cells Elicited by Multiple Peptide Immunization in Mice Revealed the Up-regulation of PD-1 Expression on Antigen-Specific CD 8 T Cells

Xian-hui He, Yi Liu, Lihui Xu, 2007 .

Phenotypic and functional analysis of LCMV gp33-41-specific CD8 T cells elicited by multiple peptide immunization in mice revealed the up-regulation of PD-1 expression on antigen-specific CD8 T cells.

Xian-hui He, Yi Liu, Lihui Xu, 2007, Cellular & molecular immunology.

Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages

C. Zhang, D. Ouyang, Xian-hui He, 2019, Front. Immunol..

Identification of major histocompatibility complex class I alleles in Chinese rhesus macaques.

D. Ouyang, Xian-hui He, Yongtang Zheng, 2008, Acta biochimica et biophysica Sinica.

Chemotherapeutic agent CPT-11 eliminates peritoneal resident macrophages by inducing apoptosis

H. Pan, D. Ouyang, Xian-hui He, 2015, Apoptosis.

Piperine metabolically regulates peritoneal resident macrophages to potentiate their functions against bacterial infection

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2015, Oncotarget.

Preparation and characterization of HLA-A*0201 tetramer loaded with IE-1316-324 antigenic peptide of human cytomegalovirus.

Xian-hui He, Lihui Xu, Hong Sun, 2006, Cellular & molecular immunology.

[Preparation of H-2Db tetramer and its application in enumerating the CD8+ T cells specific for lymphocytic choriomeningitis virus].

Xian-hui He, Yi Liu, Lihui Xu, 2008, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

High level expression of HLA-A*0203-BSP fusion protein in Escherichia coli and construction of soluble HLA-A*0203 monomer and tetramer loaded with Epstein-Barr virus peptide.

Xian-hui He, Lihui Xu, Feng-yao Li, 2007, Cellular & molecular immunology.

[Improved expression of HLA-A* 2402-BSP in Escherichia coli and its tetramer preparation].

Xian-hui He, Li-hui Xu, Feng-yao Li, 2007, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Piperine Suppresses the Expression of CXCL8 in Lipopolysaccharide-Activated SW480 and HT-29 Cells via Downregulating the Mitogen-Activated Protein Kinase Pathways

H. Pan, D. Ouyang, Xian-hui He, 2014, Inflammation.

A mini-review on ion fluxes that regulate NLRP3 inflammasome activation.

D. Ouyang, Xian-hui He, Chen-guang Li, 2020, Acta biochimica et biophysica Sinica.

Inhibitory effects of berberine on the activation and cell cycle progression of human peripheral lymphocytes.

Xian-hui He, Yi Liu, Lihui Xu, 2005, Cellular & molecular immunology.

Berberine augments hypertrophy of colonic patches in mice with intraperitoneal bacterial infection.

D. Ouyang, Xian-hui He, Yao-feng Wang, 2020, International immunopharmacology.

Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway.

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2016, Toxicology and applied pharmacology.

Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation

C. Zhang, D. Ouyang, Xian-hui He, 2019, Front. Pharmacol..

Dextran sodium sulfate potentiates NLRP3 inflammasome activation by modulating the KCa3.1 potassium channel in a mouse model of colitis

D. Ouyang, Xian-hui He, Li-hui Xu, 2022, Cellular & Molecular Immunology.

Inhibition of NLRP3 Inflammasome Activation and Pyroptosis in Macrophages by Taraxasterol Is Associated With Its Regulation on mTOR Signaling

D. Ouyang, Xian-hui He, Yao-feng Wang, 2021, Frontiers in Immunology.

Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling

D. Ouyang, Xian-hui He, Yao-feng Wang, 2020, Acta pharmaceutica Sinica. B.

Chloroquine Differentially Modulates Inflammatory Cytokine Expression in RAW 264.7 Cells in Response to Inactivated Staphylococcus aureus

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2014, Inflammation.

Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages.

D. Ouyang, Xian-hui He, Yao-feng Wang, 2013, International immunopharmacology.

Human endogenous retroviral syncytin exerts inhibitory effect on invasive phenotype of B16F10 melanoma cells.

D. Ouyang, Xian-hui He, Lihui Xu, 2013, Chinese journal of cancer research = Chung-kuo yen cheng yen chiu.

[Preparation and identification of human soluble sPD-L1 and its antibodies].

Xian-hui He, Li-hui Xu, Feng-yao Li, 2007, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Expression and purification of soluble human programmed death-1 in Escherichia coli.

Xian-hui He, Yi Liu, Lihui Xu, 2006, Cellular & molecular immunology.

Conversion of trichosanthin-induced CD95 (Fas) type I into type II apoptotic signaling during Herpes simplex virus infection.

Xian-hui He, DongXu He, Siu-cheung Tam, 2011, Molecular immunology.

Dimethyl fumarate ameliorates autoimmune hepatitis in mice by blocking NLRP3 inflammasome activation.

D. Ouyang, Xian-hui He, Bo Zeng, 2022, International immunopharmacology.

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling

H. Pan, D. Ouyang, Xian-hui He, 2016, Oncotarget.

Indoleamine 2,3-Dioxygenase (IDO) Downregulates the Cell Surface Expression of the CD4 Molecule

Xian-hui He, Guanyou Huang, Congrong Zhou, 2012, International journal of molecular sciences.

VASP Activation via the Gα13/RhoA/PKA Pathway Mediates Cucurbitacin-B-Induced Actin Aggregation and Cofilin-Actin Rod Formation

D. Ouyang, Xian-hui He, Q. Lu, 2014, PloS one.

Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation

D. Ouyang, Xian-hui He, Li-hui Xu, 2013, Inflammation Research.

Suppression of STAT3 phosphorylation enhances the cytotoxicity of cucurbitacin B in B16F10 melanoma cells

D. Ouyang, Xian-hui He, Li-hui Xu, 2012 .

ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages

C. Zhang, D. Ouyang, Xian-hui He, 2019, Apoptosis.

Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells

C. Zhang, D. Ouyang, Xian-hui He, 2018, Front. Immunol..

Piperine Suppresses Pyroptosis and Interleukin-1β Release upon ATP Triggering and Bacterial Infection

H. Pan, D. Ouyang, Xian-hui He, 2016, Front. Pharmacol..

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways

Xian-hui He, Li-hui Xu, Bo Zeng, 2021, Acta Pharmacologica Sinica.

The Signaling Pathways Regulating NLRP3 Inflammasome Activation

D. Ouyang, Xian-hui He, Ming-ye Chen, 2021, Inflammation.

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis

D. Ouyang, Xian-hui He, Yi Liu, 2018, Front. Pharmacol..

Endogenous HIV-1 Vpr-mediated apoptosis and proteome alteration of human T-cell leukemia virus-1 transformed C8166 cells

Tuofu Zhu, Xian-hui He, Xiaoping Wu, 2009, Apoptosis.

Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2015, PloS one.

Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5

D. Ouyang, Xian-hui He, Dong-Yun Ouyang, 2013, Autophagy.

Caspase‐3‐mediated GSDME activation contributes to cisplatin‐ and doxorubicin‐induced secondary necrosis in mouse macrophages

D. Ouyang, Xian-hui He, Bo Hu, 2019, Cell proliferation.

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

D. Ouyang, Xian-hui He, Yao-feng Wang, 2019, Apoptosis.

The Second-Generation mTOR Kinase Inhibitor INK128 Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells

H. Pan, D. Ouyang, Xian-hui He, 2014, Inflammation.

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

D. Ouyang, Xian-hui He, Yao-feng Wang, 2019, Apoptosis.

Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation

D. Ouyang, Xian-hui He, Mark Saltis, 2012, Cancer Chemotherapy and Pharmacology.

Quantitative Proteomics Analysis of Chondrogenic Differentiation of C3H10T1/2 Mesenchymal Stem Cells by iTRAQ Labeling Coupled with On-line Two-dimensional LC/MS/MS*

Xian-hui He, Yu Yu, Yu-hua Ji, 2009, Molecular & Cellular Proteomics.

The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2015, Oncotarget.

ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages

H. Pan, D. Ouyang, Xian-hui He, 2016, Front. Immunol..

One in vitro model for visceral adipose-derived fibroblasts in chronic inflammation.

Xian-hui He, T. Xia, S. Feng, 2005, Biochemical and biophysical research communications.

Differential cell surface expression of rhesus macaque's major histocompatibility complex class I alleles Mamu-B*1703 and Mamu-B*0101.

D. Ouyang, Xian-hui He, Xichao Wang, 2010, Acta biochimica et biophysica Sinica.

Cucurbitacin IIb Exhibits Anti-Inflammatory Activity through Modulating Multiple Cellular Behaviors of Mouse Lymphocytes

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2014, PloS one.

Identification of a novel splice variant of human PD-L1 mRNA encoding an isoform-lacking Igv-like domain

Xian-hui He, Yi Liu, Li‐hui Xu, 2005, Acta Pharmacologica Sinica.

Histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti-inflammatory activities through induction of mitochondrial damage and apoptosis in activated lymphocytes.

D. Ouyang, Xian-hui He, Zi-jian Shi, 2012, International immunopharmacology.

The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis

Xian-hui He, Hong Lu, J. Di, 2009, Acta Pharmacologica Sinica.

Suppression of STAT 3 phosphorylation enhances the cytotoxicity of cucurbitacin B in B 16 F 10 melanoma cells

D. Ouyang, Xian-hui He, Yan-ting Zhang, 2012 .

Dimethyl fumarate inhibits necroptosis and alleviates systemic inflammatory response syndrome by blocking the RIPK1-RIPK3-MLKL axis.

Xian-hui He, Yi-Ping You, Zi-jian Shi, 2023, Pharmacological research.

Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment.

D. Ouyang, Xian-hui He, Lihui Xu, 2011, Acta biochimica et biophysica Sinica.

Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice.

D. Ouyang, Xian-hui He, Yi-Ping You, 2023, International immunopharmacology.

Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol

D. Ouyang, Xian-hui He, Lihui Xu, 2021, Acta biochimica et biophysica Sinica.

Valproic acid synergistically enhances the cytotoxicity of gossypol in DU145 prostate cancer cells: an iTRTAQ-based quantitative proteomic analysis.

D. Ouyang, Xian-hui He, Yu-hua Ji, 2011, Journal of proteomics.

Cucurbitacin E suppresses cytokine expression in human Jurkat T cells through down-regulating the NF-κB signaling.

H. Pan, D. Ouyang, Xian-hui He, 2015, Acta biochimica et biophysica Sinica.

Taraxasterol mitigates Con A-induced hepatitis in mice by suppressing interleukin-2 expression and its signaling in T lymphocytes

D. Ouyang, Xian-hui He, Bo Zeng, 2021, International Immunopharmacology.

Formation of cofilin–actin rods following cucurbitacin‐B‐induced actin aggregation depends on slingshot homolog 1‐mediated cofilin hyperactivation

D. Ouyang, Xian-hui He, Yan-ting Zhang, 2013, Journal of cellular biochemistry.

Cucurbitacin B Induces Cell Cycle Arrest, Apoptosis and Autophagy Associated with G Actin Reduction and Persistent Activation of Cofilin in Jurkat Cells

D. Ouyang, Xian-hui He, Yan-ting Zhang, 2012, Pharmacology.

Enhancement of binding activity of soluble human CD40 to CD40 ligand through incorporation of an isoleucine zipper motif

Xian-hui He, Yi Liu, Li‐hui Xu, 2006, Acta Pharmacologica Sinica.

Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells.

Jiye Cai, D. Ouyang, Xian-hui He, 2011, Acta biochimica et biophysica Sinica.

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways

Xian-hui He, Bo Zeng, Qing-bing Zha, 2021, Acta Pharmacologica Sinica.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Theaflavin mitigates acute gouty peritonitis and septic organ injury in mice by suppressing NLRP3 inflammasome assembly

Xian-hui He, Yi-Ping You, Zi-jian Shi, 2023, Acta Pharmacologica Sinica.

The Second-Generation mTOR Kinase Inhibitor INK128 Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells

H. Pan, D. Ouyang, Xian-hui He, 2014, Inflammation.

Piperine Suppresses the Expression of CXCL8 in Lipopolysaccharide-Activated SW480 and HT-29 Cells via Downregulating the Mitogen-Activated Protein Kinase Pathways

H. Pan, D. Ouyang, Xian-hui He, 2014, Inflammation.

High Frequencies Cytomegalovirus pp65495–503-Specific CD8+ T Cells in Healthy Young and Elderly Chinese Donors: Characterization of Their Phenotypes and TCR Vβ Usage

Xian-hui He, Yi Liu, Xiao-yun Chi, 2006, Journal of Clinical Immunology.

Chemotherapeutic agent CPT-11 eliminates peritoneal resident macrophages by inducing apoptosis

H. Pan, D. Ouyang, Xian-hui He, 2016, Apoptosis.

[Cloning of human beta-microglobulin gene and its high expression in Escherichia coli].

Xian-hui He, Yi Liu, Yao-ying Zeng, 2004, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Construction of Soluble Mamu-B*1703, a Class I Major Histocompatibility Complex of Chinese Rhesus Macaques, Monomer and Tetramer Loaded with a Simian Immunodeficiency Virus Peptide

D. Ouyang, Xian-hui He, Xiaoying Wang, 2009, Cellular and Molecular Immunology.

CD8(+) T cells specific for both persistent and non-persistent viruses display distinct differentiation phenotypes but have similar level of PD-1 expression in healthy Chinese individuals.

Xian-hui He, Yi Liu, Mark Saltis, 2008, Clinical immunology.

Injection of Escherichia coli to Induce Sepsis.

D. Ouyang, Xian-hui He, Li‐hui Xu, 2021, Methods in molecular biology.

Triptolide induces PANoptosis in macrophages and causes organ injury in mice

D. Ouyang, Xian-hui He, Yi-Ping You, 2023, Apoptosis.

Chloroquine Differentially Modulates Inflammatory Cytokine Expression in RAW 264.7 Cells in Response to Inactivated Staphylococcus aureus

Gao-Xiang Zhao, H. Pan, D. Ouyang, 2015, Inflammation.

Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation

D. Ouyang, Xian-hui He, Jian He, 2013, Inflammation Research.

Anti-Necroptotic Effects of Itaconate and its Derivatives

D. Ouyang, Xian-hui He, Rong Xu, 2023, Inflammation.