Dong Zhang

发表

Nucleocytoplasmic Translocation of UBXN 2 A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells

A. Abdullah, S. Sane, Jessica L. Freeling, 2015 .

Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response

Steven P Gygi, B. A. Ballif, S. Elledge, 2007, Science.

Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β

Aroop Sircar, Dong Zhang, H. Sabzevari, 2018, Science Translational Medicine.

A murine preclinical syngeneic transplantation model for breast cancer precision medicine

Jennifer B Dennison, C. Perou, G. Mills, 2017, Science Advances.

PKC iota promotes ovarian tumor progression through deregulation of cyclin E

G. Mills, K. Hunt, K. Keyomarsi, 2015, Oncogene.

Roles of SAMHD1 in antiviral defense, autoimmunity and cancer

Jun Li, Dong Zhang, Wei Wei, 2017, Reviews in medical virology.

Low-dose 5-fluorouracil sensitizes HepG2 cells to TRAIL through TRAIL receptor DR5 and survivin-dependent mechanisms

Dong Zhang, Tao Yang, Gongqin Sun, 2017, Journal of chemotherapy.

Identification and characterization of M6903, an antagonistic anti–TIM-3 monoclonal antibody

Dong Zhang, D. Musil, D. Nannemann, 2020, Oncoimmunology.

1α,25-Dihydroxyvitamin D3 up-regulates IL-34 expression in SH-SY5Y neural cells

Y. Dong, S. Fang, Dong Zhang, 2017, Innate immunity.

A Role for the Deubiquitinating Enzyme USP28 in Control of the DNA-Damage Response

T. Mak, Dong Zhang, S. Elledge, 2006, Cell.

Substitution of the Echistatin Amino Acid Motif RGDD with KGDW Enhances Inhibition of Platelet Aggregation and Thrombogenesis

Dong Zhang, Tao Yang, B. Niu, 2015, International Journal of Peptide Research and Therapeutics.

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade

T. Ludwig, J. Parvin, C. Canman, 2013, Proceedings of the National Academy of Sciences.

AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model

Yuquan Wei, C. Gong, Xia Zhao, 2012, BMC Cancer.

Antitumor and anti‐angiogenesis immunity induced by CR‐SEREX‐identified Xenopus RHAMM

Dong Zhang, Yu‐quan Wei, H. Deng, 2010, Cancer science.

The Proteasome Function Reporter GFPu Accumulates in Young Brains of the APPswe/PS1dE9 Alzheimer’s Disease Mouse Model

Hongmin Wang, Dong Zhang, K. Rezvani, 2014, Cellular and Molecular Neurobiology.

YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway.

G. Mills, Z. Ju, Yiling Lu, 2017, Cancer research.

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency.

G. Mills, Z. Ju, Yiling Lu, 2018, Cancer cell.

Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells

A. Abdullah, S. Sane, Jessica L. Freeling, 2015, Journal of Cancer.

Calretinin interacts with huntingtin and reduces mutant huntingtin‐caused cytotoxicity

M. Ueffing, Hongmin Wang, Dong Zhang, 2012, Journal of neurochemistry.

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

Yiling Lu, Gordon B Mills, Zhenlin Ju, 2014, Cancer cell.

Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2.

Zhihong Wu, Dong Zhang, Shu-yang Zhang, 2018, Biochemical and biophysical research communications.

FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1

Hongmin Wang, Dong Zhang, K. Rezvani, 2013, Biology Open.

BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress

Hongmin Wang, Dong Zhang, K. Rezvani, 2013, Cell cycle.

Ubiquilin-1 Protects Cells from Oxidative Stress and Ischemic Stroke Caused Tissue Injury in Mice

Lanhai Lü, Hongmin Wang, Dong Zhang, 2014, The Journal of Neuroscience.

Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models

Jennifer B Dennison, G. Mills, J. Ajani, 2011, Molecular Cancer Therapeutics.

[Effects of Cullin1 on the Biological Characteristics of Lung Adenocarcinoma A549 and H1395 Cells].

Dong Zhang, Jingyi Liu, Huijie He, 2021, Zhongguo fei ai za zhi = Chinese journal of lung cancer.

Mdm-MIR393b-mediated adventitious root formation by targeted regulation of MdTIR1A expression and weakened sensitivity to auxin in apple rootstock.

Dong Zhang, Jiangping Mao, Ke Li, 2021, Plant science : an international journal of experimental plant biology.

Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

G. Mills, Z. Ju, Yiling Lu, 2017, Science Translational Medicine.

Interferon induced transmembrane protein 3 regulates the growth and invasion of human lung adenocarcinoma

Y. Li, Dong Zhang, Huijie He, 2017, Thoracic cancer.

Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.

G. Mills, Yongsheng Li, Z. Ju, 2019, Cancer cell.

Substitution of the Echistatin Amino Acid Motif RGDD with KGDW Enhances Inhibition of Platelet Aggregation and Thrombogenesis

Dong Zhang, Tao Yang, B. Niu, 2015, International Journal of Peptide Research and Therapeutics.

Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer.

Prahlad T. Ram, G. Mills, P. Ram, 2016, Cell reports.

Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T Cells in Tumors from Mice and Humans

S. Takai, Dong Zhang, H. Sabzevari, 2015, The Journal of Immunology.

Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

G. Mills, A. Børresen-Dale, K. Chin, 2014, Cancer cell.

BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1

Deli Zhang, Hongmin Wang, Dong Zhang, 2014, Cell cycle.

Direct Reprogramming of Huntington’s Disease Patient Fibroblasts into Neuron-Like Cells Leads to Abnormal Neurite Outgrowth, Increased Cell Death, and Aggregate Formation

Xiang-Dong Fu, Hongmin Wang, Dong Zhang, 2014, PloS one.

Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease

Hongmin Wang, Dong Zhang, K. Rezvani, 2014, Journal of neurochemistry.

miR-155 regulates high glucose-induced cardiac fibrosis via the TGF-β signaling pathway.

B. Li, Dong Zhang, Yongchun Cui, 2016, Molecular bioSystems.

Abstract 1416: CB-839, a novel potent and selective glutaminase inhibitor, has broad antiproliferative activity in cell lines derived from both solid tumors and hematological malignancies

S. Demo, Dong Zhang, M. Bennett, 2014 .

Overexpressed microRNA-494 represses RIPK1 to attenuate hippocampal neuron injury in epilepsy rats by inactivating the NF-κB signaling pathway

Dong Zhang, R. Qian, Xian-ming Fu, 2020, Cell cycle.

miR‐148a‐3p silences the CANX/MHC‐I pathway and impairs CD8+ T cell‐mediated immune attack in colorectal cancer

Y. Xi, Dong Zhang, T. Yang, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MiR-485-5p promotes neuron survival through mediating Rac1/Notch2 signaling pathway after cerebral ischemia/reperfusion.

Dong Zhang, Xuan Chen, Peipei Shi, 2020, Current neurovascular research.

Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling

Katie M. Reindl, Dong Zhang, Liang Han, 2014, BMC Cancer.

Abstract B154: Application of preclinical combination pharmacokinetic(PK)/efficacy(E) modeling to investigate and translate the preclinical scheduling effect for MLN1117 and Taxotere combination

Dong Zhang, K. Kannan, C. Zopf, 2015 .

p85β regulates autophagic degradation of AXL to activate oncogenic signaling

G. Mills, Yiling Lu, A. Cheung, 2020, Nature Communications.

Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

Prahlad T. Ram, G. Mills, A. Børresen-Dale, 2014, Cancer cell.

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

G. Mills, Z. Ju, Yiling Lu, 2014, Cancer cell.

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade

T. Ludwig, J. Parvin, C. Canman, 2013, Proceedings of the National Academy of Sciences.

The regulation of SKF38393 on the signaling pathway of dopamine D1 receptor in hippocampus during chronic sleep deprivation

Dong Zhang, Hanyang Liang, Xiao-sa Wen, 2017, Neuroscience Letters.

p85β regulates autophagic degradation of AXL to activate oncogenic signaling

G. Mills, Yiling Lu, D. Zhang, 2020, Nature Communications.