W. Du

发表

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

K. Wellen, A. Mancuso, P. Jiang, 2012, Nature.

Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins*

Hongda Huang, Jiahai Zhang, P. Jiang, 2007, Journal of Biological Chemistry.

Siva1 suppresses epithelial–mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules

P. Jiang, W. Du, Xiaolu Yang, 2011, Proceedings of the National Academy of Sciences.

Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase

P. Jiang, W. Du, Yide Mei, 2013, Nature Communications.

LKB1-AMPK axis negatively regulates ferroptosis by inhibiting fatty acid synthesis

Minghui Gao, Kangjie Chen, W. Du, 2019, Signal Transduction and Targeted Therapy.

A transformation clustering algorithm and its application in polyribosomes structural profiling

W. Baumeister, W. Du, F. Beck, 2022, Nucleic acids research.

Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis

P. Jiang, W. Du, Taiqi Chen, 2022, EMBO reports.

LKB1-AMPK axis negatively regulates ferroptosis by inhibiting fatty acid synthesis

Minghui Gao, Kangjie Chen, W. Du, 2020, Signal Transduction and Targeted Therapy.

Expression and function assessment of two serpin-type serine protease inhibitors from Haemaphysalis doenitzi.

W. Du, Jingze Liu, Peijing Zheng, 2020, Research in veterinary science.

Regulation of the pentose phosphate pathway in cancer

P. Jiang, W. Du, Mian Wu, 2014, Protein & Cell.

p53 and regulation of tumor metabolism

P. Jiang, W. Du, Xiaolu Yang, 2013, Journal of carcinogenesis.

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

A. Mancuso, P. Jiang, W. Du, 2011, Nature Cell Biology.

Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions

P. Jiang, W. Du, Chang Xu, 2017, The Journal of Biological Chemistry.

LRG1 expression reduced inflammation of sepsis-renal injury via activation of NLRP3 inflammasome by HIF-1 alpha

W. Du, Y-H Bai, Y. Sang, 2022, Molecular & Cellular Toxicology.

The Bad Guy Cooperates with Good Cop p53: Bad Is Transcriptionally Up-Regulated by p53 and Forms a Bad/p53 Complex at the Mitochondria To Induce Apoptosis

Klaus Heese, Mian Wu, P. Jiang, 2006, Molecular and Cellular Biology.

p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Le Li, P. Jiang, Lina Zhao, 2019, Nature.

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

T. Mak, A. Mancuso, A. Minn, 2013, Nature Cell Biology.

Puma*Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1

W. Du, Yide Mei, Mian Wu, 2005, Oncogene.

p53 and Bad: remote strangers become close friends

Mian Wu, P. Jiang, W. Du, 2007, Cell Research.

MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE

W. Du, Zizhao Liu, J. Kou, 2021, Frontiers in Cell and Developmental Biology.

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

D. Wang, Le Li, P. Jiang, 2018, Nature Communications.

A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation

P. Jiang, W. Du, Xiaolu Yang, 2013, Cell cycle.

MYC retards cancer cell migration through suppressing fibronectin expression.

P. Jiang, W. Du, Mengjia Zhao, 2019, Science bulletin.

Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Le Li, P. Jiang, W. Du, 2019, Nature.

NADPH levels affect cellular epigenetic state by inhibiting HDAC3–Ncor complex

W. Du, Wei Li, Junying Qin, 2021, Nature Metabolism.

NADPH levels affect cellular epigenetic state by inhibiting HDAC3–Ncor complex

W. Du, J. Kou, Wei Li, 2021, Nature Metabolism.

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

T. Mak, Le Li, P. Jiang, 2018, Nature Communications.

p53 protects against alcoholic fatty liver disease via ALDH2 inhibition

P. Jiang, W. Du, Wei Li, 2023, The EMBO journal.

Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Le Li, P. Jiang, Lina Zhao, 2019, Nature.

Malic enzyme 2 as a therapeutic target for cancer: comments on ‘Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate’

W. Du, Zhenxi Zhang, 2022, Journal of molecular cell biology.

Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate

P. Jiang, W. Du, Jinjun Wu, 2022, Nature Metabolism.

ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate

W. Du, Wei Li, Ying Zhou, 2023, Metabolites.

αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.

W. Du, Wei Li, Li Li, 2023, Cell reports.

p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth

W. Du, Zizhao Liu, Wei Li, 2021, EMBO reports.

Suppression of p53 activity by Siva1

P. Jiang, W. Du, Xiaolu Yang, 2009, Cell Death and Differentiation.

Livin promotes Smac/DIABLO degradation by ubiquitin–proteasome pathway

W. Du, W. Du, Yafen Huang, 2006, Cell Death and Differentiation.

p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Le Li, P. Jiang, Lina Zhao, 2019, Nature.

Inactivation of Malic Enzyme 1 in Endothelial Cells Alleviates Pulmonary Hypertension

W. Du, Jing Wang, Ran Gao, 2024, Circulation.

AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis

W. Du, Taiqi Chen, Jie Cheng, 2024, Nature communications.