C. Velez-Pardo

发表

Pro-apoptotic effect of Persea americana var. Hass (avocado) on Jurkat lymphoblastic leukemia cells

A. Bonilla-Porras, A. Salazar-Ospina, M. Jimenez-Del-Rio, 2014, Pharmaceutical biology.

Insulin-like growth factor-1 prevents Aβ[25–35]/(H2O2)- induced apoptosis in lymphocytes by reciprocal NF-κB activation and p53 inhibition via PI3K-dependent pathway

C. Velez-Pardo, M. Jiménez Del Río, 2006, Growth factors.

Effects of insulin-like growth factor-1 on rotenone-induced apoptosis in human lymphocyte cells.

M. Jimenez-Del-Rio, C. Velez-Pardo, I. C. Ávila-Gómez, 2009, Basic & clinical pharmacology & toxicology.

PARKIN overexpression in human mesenchymal stromal cells from Wharton's jelly suppresses 6-hydroxydopamine-induced apoptosis: Potential therapeutic strategy in Parkinson's disease.

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2018, Cytotherapy.

Phenolic‐rich extract of avocado Persea americana (var. Colinred) peel blunts paraquat/maneb‐induced apoptosis through blocking phosphorylation of LRRK2 kinase in human nerve‐like cells

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2021, Environmental toxicology.

Distribution of APOE polymorphism in the “Paisa” population from northwest Colombia (Antioquia)

W. Rojas, G. Bedoya, M. Jimenez-Del-Rio, 2015, Annals of human biology.

New mutation (T1232P) of the ATP-7B gene associated with neurologic and neuropsychiatric dominance onset of Wilson’s disease in three unrelated Colombian kindred

F. Lopera, C. Velez-Pardo, S. Moreno, 2004, Neuroscience Letters.

Glucose promotes resistance in lymphocytes against oxidative stress-induced apoptosis through signaling and metabolic pathways. Implications for Parkinson’s disease

M. Jimenez-Del-Rio, C. Velez-Pardo, Leonardo Bonilla-Ramírez, 2017 .

Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson’s disease (LARGE-PD), a case of ancestry

F. Micheli, F. Lopera, I. Mata, 2017, npj Parkinson's Disease.

Doxorubicin induces apoptosis in Jurkat cells by mitochondria-dependent and mitochondria-independent mechanisms under normoxic and hypoxic conditions

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2015, Anti-cancer drugs.

Polycationic peptide R7-G-Aβ25-35 selectively induces cell death in leukemia Jurkat T cells through speedy mitochondrial depolarization, and CASPASE-3 -independent mechanism

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2022, Biochemistry and biophysics reports.

Combinational treatment of TPEN and TPGS induces apoptosis in acute lymphoblastic and chronic myeloid leukemia cells in vitro and ex vivo

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2022, Medical Oncology.

Cannabinoid CP55940 selectively induces apoptosis in Jurkat cells and in ex vivo T-cell acute lymphoblastic leukemia through H2O2 signaling mechanism.

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2020, Leukemia research.

Glucose Starvation Induces Apoptosis in a Model of Acute T Leukemia Dependent on Caspase-3 and Apoptosis-Inducing Factor: A Therapeutic Strategy

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2013, Nutrition and cancer.

Fructose sensitizes Jurkat cells oxidative stress‐induced apoptosis via caspase‐dependent and caspase‐independent mechanisms

M. Jimenez-Del-Rio, C. Velez-Pardo, Viviana Diaz-Aguirre, 2016, Cell biology international.

TPEN Induces Apoptosis Independently of Zinc Chelator Activity in a Model of Acute Lymphoblastic Leukemia and Ex Vivo Acute Leukemia Cells through Oxidative Stress and Mitochondria Caspase-3- and AIF-Dependent Pathways

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2012, Oxidative medicine and cellular longevity.

Vitamin E d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS) Provokes Cell Death in Human Neuroblastoma SK-N-SH Cells via a Pro-Oxidant Signaling Mechanism.

M. Jimenez-Del-Rio, C. Velez-Pardo, Cristian Ruiz-Moreno, 2018, Chemical research in toxicology.

Autosomal Recessive Juvenile Parkinsonism Cys212tyr Mutation in Parkin Renders Lymphocytes Susceptible to Dopamine-and Iron-mediated Apoptosis Patients and Methods

F. Lopera, C. Velez-Pardo, M. Jiménez Del Río, 2022 .

Autosoma lRecessiv eJuvenile Parkinsonism Cys212Tyr Mutation i nParki nRender sLymphocytes Susceptibl et oDopamine -and Iron-Mediated Apoptosis

F. Lopera, C. Velez-Pardo, O. Buritica, 2004 .

Human Lymphocytes and Drosophila melanogaster as Model System to Study Oxidative Stress in Parkinson's Disease

M. Jimenez-Del-Rio, C. Velez-Pardo, 2012 .

Oxidative stress signaling and regulated cell death in Parkinson's disease

M. Jimenez-Del-Rio, C. Velez-Pardo, 2020 .

Metal chelator TPEN selectively induces apoptosis in K562 cells through reactive oxygen species signaling mechanism: implications for chronic myeloid leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, L. Rojas-Valencia, 2017, BioMetals.

Vitamin E synthetic derivate—TPGS—selectively induces apoptosis in jurkat t cells via oxidative stress signaling pathways: implications for acute lymphoblastic leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, Cristian Ruiz-Moreno, 2016, Apoptosis.

Serotonin binding proteins "SBP": target proteins and tool for in vitro neurotoxicity studies.

C. Velez-Pardo, G. Vauquelin, G. Ebinger, 1995, General pharmacology.

Minocycline induces apoptosis in acute lymphoblastic leukemia Jurkat cells.

M. Jimenez-Del-Rio, C. Velez-Pardo, Cristian Ruiz-Moreno, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Using paraquat to generate anion free radicals and hydrogen peroxide in in vitro: Antioxidant effect of vitamin E

M. Jimenez-Del-Rio, C. Velez-Pardo, Gerson Suarez-Cedeño, 2010, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology.

Multi-Target Effects of the Cannabinoid CP55940 on Familial Alzheimer's Disease PSEN1 E280A Cholinergic-Like Neurons: Role of CB1 Receptor.

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2020, Journal of Alzheimer's disease : JAD.

Role of a novel (−)-epigallocatechin-3-gallate delivery system on the prevention against oxidative stress damage in vitro and in vivo model of Parkinson's disease

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2020 .

Purification of nasulysin-1: A new toxin from Porthidium nasutum snake venom that specifically induces apoptosis in leukemia cell model through caspase-3 and apoptosis-inducing factor activation.

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2016, Toxicon : official journal of the International Society on Toxinology.

TPEN Exerts Antitumor Efficacy in Murine Mammary Adenocarcinoma Through an H2O2 Signaling Mechanism Dependent on Caspase-3.

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2019, Anti-cancer agents in medicinal chemistry.

TPEN selectively eliminates lymphoblastic B cells from bone marrow pediatric acute lymphoblastic leukemia patients.

M. Jimenez-Del-Rio, C. Velez-Pardo, M. Mendivil-Perez, 2022, Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.

(−)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer’s Disease PSEN1 E280A

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2021, Biomolecules.

TPEN Selectively Eliminates Lymphoblastic B Cells from Pediatric Acute Lymphoblastic Lleukemia Patients

M. Jimenez-Del-Rio, C. Velez-Pardo, M. Mendivil-Perez, 2021 .

TPEN exerts selective anti-leukemic efficacy in ex vivo drug-resistant childhood acute leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2020, BioMetals.

N-acetyl-cysteine blunts 6-hydroxydopamine- and l-buthionine-sulfoximine-induced apoptosis in human mesenchymal stromal cells

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2019, Molecular Biology Reports.

L-amino acid oxidase isolated from Micrurus mipartitus snake venom (MipLAAO) specifically induces apoptosis in acute lymphoblastic leukemia cells mostly via oxidative stress-dependent signaling mechanism.

M. Jimenez-Del-Rio, C. Velez-Pardo, V. Núñez, 2019, International journal of biological macromolecules.

Design of epigallocatechin gallate loaded PLGA/PF127 nanoparticles and their effect upon an oxidative stress model

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2018, Journal of Drug Delivery Science and Technology.

From Dark to Bright to Gray Sides of Memory: In Search of its Molecular Basis & Alzheimer’s Disease

C. Velez-Pardo, 2015 .

Latent Tri-lineage Potential of Human Menstrual Blood–Derived Mesenchymal Stromal Cells Revealed by Specific In Vitro Culture Conditions

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2021, Molecular Neurobiology.

Direct transdifferentiation of human Wharton’s jelly mesenchymal stromal cells into cholinergic-like neurons

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2019, Journal of Neuroscience Methods.

Minocycline protects, rescues and prevents knockdown transgenic parkin Drosophila against paraquat/iron toxicity: Implications for autosomic recessive juvenile parkinsonism

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2017, Neurotoxicology.

Ancestral association between HLA and HFE H63D and C282Y gene mutations from northwest Colombia

M. Jimenez-Del-Rio, C. Velez-Pardo, Cristiam M. Álvarez, 2014, Genetics and molecular biology.

Analysis of the HFE gene (H63D and C282Y) mutations in patients with iron overload, family members and controls from Antioquia, Northwest Colombia

M. Jimenez-Del-Rio, C. Velez-Pardo, I. C. Ávila-Gómez, 2007, Clinical genetics.

Association between HFE 187 C>G (H63D) mutation and early-onset familial Alzheimer’s disease PSEN-1 839A>C (E280A) mutation

M. Jimenez-Del-Rio, C. Velez-Pardo, I. C. Ávila-Gómez, 2008, Annals of Hematology.

Manganese and copper promote the binding of dopamine to “serotonin binding proteins” in bovine frontal cortex

C. Velez-Pardo, G. Vauquelin, G. Ebinger, 1995, Neurochemistry International.

Prevalence of H63D, S65C and C282Y mutations of the HFE gene in 1120 voluntary blood donors from Antioquia region of northwest Colombia.

M. Jimenez-Del-Rio, C. Velez-Pardo, I. C. Ávila-Gómez, 2008, Blood cells, molecules & diseases.

Endogenously generated hydrogen peroxide induces apoptosis via mitochondrial damage independent of NF-kappaB and p53 activation in bovine embryos.

C. Velez-Pardo, M. Olivera-Angel, M. J. Del Rio, 2007, Theriogenology.

Monoamine and iron-related toxicity: from "serotonin-binding proteins" to lipid peroxidation and apoptosis in PC12 cells.

C. Velez-Pardo, G. Vauquelin, G. Ebinger, 1998, General pharmacology.

Dopamine and iron induce apoptosis in PC12 cells.

H. Verschueren, C. Velez-Pardo, M. Jiménez Del Río, 1997, Pharmacology & toxicology.

Redox cycling activity of monoamine-serotonin binding protein conjugates.

C. Velez-Pardo, M. Jiménez Del Río, G. Vauquelin, 1996, Biochemical pharmacology.

Acute and chronic metal exposure impairs locomotion activity in Drosophila melanogaster: a model to study Parkinsonism

M. Jimenez-Del-Rio, C. Velez-Pardo, Leonardo Bonilla-Ramírez, 2011, BioMetals.

Neuroprotective Effects of Methanolic Extract of Avocado Persea americana (var. Colinred) Peel on Paraquat-Induced Locomotor Impairment, Lipid Peroxidation and Shortage of Life Span in Transgenic knockdown Parkin Drosophila melanogaster

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2019, Neurochemical Research.

The Effects of Polyphenols on Survival and Locomotor Activity in Drosophila melanogaster Exposed to Iron and Paraquat

M. Jimenez-Del-Rio, C. Velez-Pardo, C. Guzmán-Martínez, 2010, Neurochemical Research.

Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function

J. García-Verdugo, M. Jimenez-Del-Rio, C. Velez-Pardo, 2017, Journal of pineal research.

Vitamin E TPGS 1000 Induces Apoptosis in the K562 Cell Line: Implications for Chronic Myeloid Leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, Jazmin Calvo-Alvarez, 2021, Oxidative medicine and cellular longevity.

Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson’s disease

M. Jimenez-Del-Rio, C. Velez-Pardo, Diana Quintero-Espinosa, 2017, Brain Research.

Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF-06447475 in Human Nerve-Like Differentiated Cells Exposed to Oxidative Stress Stimuli: Implications for Parkinson’s Disease

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2016, Neurochemical Research.

Aβ[25–35] Peptide and Iron Promote Apoptosis in Lymphocytes by an Oxidative Stress Mechanism: Involvement of H2O2, Caspase-3, NF-κB, p53 and c-Jun

C. Velez-Pardo, M. J. Rio, G. G. Ospina, 2002 .

TPEN/TPGS (T2) combo dramatically reduces Philadelphia chromosome-positive pro-lymphoblastic B leukemia in BALB/c mice

M. Jimenez-Del-Rio, C. Velez-Pardo, M. Mendivil-Perez, 2022, Medical Oncology.

Protective Effects of the Synthetic Cannabinoids CP55,940 and JWH-015 on Rat Brain Mitochondria upon Paraquat Exposure

M. Jimenez-Del-Rio, C. Velez-Pardo, J. Bustamante, 2010, Neurochemical Research.

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

Kewei Chen, Eric M Reiman, Francisco Lopera, 2012, The Lancet Neurology.

Response to Rotenone Is Glucose-Sensitive in a Model of Human Acute Lymphoblastic Leukemia: Involvement of Oxidative Stress Mechanism, DJ-1, Parkin, and PINK-1 Proteins

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2014, Oxidative medicine and cellular longevity.

The distribution and risk effect of GBA variants in a large cohort of PD patients from Colombia and Peru.

F. Lopera, I. Mata, M. Jimenez-Del-Rio, 2019, Parkinsonism & related disorders.

TPEN exerts selective anti-leukemic efficacy in ex vivo drug-resistant childhood acute leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2020, BioMetals.

Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer’s disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications

F. Lopera, M. Jimenez-Del-Rio, C. Velez-Pardo, 2020, PloS one.

X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson Disease

T. Thornton, F. Lopera, T. O’Connor, 2023, medRxiv.

Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2011, Cancer Cell International.

Familial Alzheimer's disease: oxidative stress, beta-amyloid, presenilins, and cell death.

F. Lopera, C. Velez-Pardo, M. Jiménez Del Río, 1998, General pharmacology.

17 beta-estradiol protects lymphocytes against dopamine and iron-induced apoptosis by a genomic-independent mechanism. Implication in Parkinson's disease.

C. Velez-Pardo, M. Jiménez Del Río, M. J. Rio, 2000, General pharmacology.

Genome‐Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients

T. Thornton, A. Horimoto, F. Lopera, 2020, medRxiv.

Transition metal-induced apoptosis in lymphocytes via hydroxyl radical generation, mitochondria dysfunction, and caspase-3 activation: an in vitro model for neurodegeneration.

C. Velez-Pardo, M. Jiménez Del Río, 2004, Archives of medical research.

Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide (H(2)O(2)), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors.

C. Velez-Pardo, Carlos Velez-Pardo, Marlene Jimenez Del Rio, 2002, Biochemical pharmacology.

Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer’s disease reveal intraneuronal Aβ42 peptide accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ flux dysregulation: Therapeutic Implications

F. Lopera, M. Jimenez-Del-Rio, C. Velez-Pardo, 2019, bioRxiv.

Vitamin E synthetic derivate—TPGS—selectively induces apoptosis in jurkat t cells via oxidative stress signaling pathways: implications for acute lymphoblastic leukemia

M. Jimenez-Del-Rio, C. Velez-Pardo, Ligia Sierra-Garcia, 2016, Apoptosis.

Alzheimer's Disease, Drosophila melanogaster and Polyphenols.

M. Jimenez-Del-Rio, C. Velez-Pardo, 2015, Advances in experimental medicine and biology.

Helping Leukemia Cells to Die with Natural or Chemical Compounds Through H2O2 Signaling

M. Jimenez-Del-Rio, C. Velez-Pardo, 2021, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

The Bad, the Good, and the Ugly about Oxidative Stress

M. Jimenez-Del-Rio, C. Velez-Pardo, 2012, Oxidative medicine and cellular longevity.

Paraquat induces apoptosis in human lymphocytes: Protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1

C. Velez-Pardo, M. Jiménez Del Río, Carlos Velez-Pardo, 2008, Growth factors.

Neuroprotective Effect of Combined Treatment with Epigallocatechin 3-Gallate and Melatonin on Familial Alzheimer's Disease PSEN1 E280A Cerebral Spheroids Derived from Menstrual Mesenchymal Stromal Cells.

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2023, Journal of Alzheimer's disease : JAD.

Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster

M. Jimenez-Del-Rio, C. Velez-Pardo, Daniel A. Martinez-Perez, 2018, Neurotoxicity Research.

The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: Implications in Parkinson's disease

M. Jimenez-Del-Rio, C. Velez-Pardo, A. Daza-Restrepo, 2008, Neuroscience Research.

Fast transdifferentiation of human Wharton’s jelly mesenchymal stem cells into neurospheres and nerve-like cells

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2017, Journal of Neuroscience Methods.

TPEN selectively eliminates lymphoblastic B cells from bone marrow pediatric acute lymphoblastic leukemia patients

M. Jimenez-Del-Rio, C. Velez-Pardo, M. Mendivil-Perez, 2021, Biometals.

CA1 Hippocampal Neuronal Loss in Familial Alzheimer's Disease Presenilin‐1 E280A Mutation Is Related to Epilepsy

J. Arellano, C. Velez-Pardo, F. Lopera, 2004, Epilepsia.

Ultrastructure evidence of necrotic neural cell death in familial Alzheimer's disease brains bearing presenilin-1 E280A mutation.

F. Lopera, C. Velez-Pardo, M. Jiménez Del Río, 2001, Journal of Alzheimer's disease : JAD.

Knockdown transgenic Drosophila and Parkinson's disease

M. Jimenez-Del-Rio, C. Velez-Pardo, 2020 .

Characterizing the Genetic Architecture of Parkinson's Disease in Latinos

T. Thornton, A. Horimoto, F. Lopera, 2020, medRxiv.

Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson’s disease (LARGE-PD), a case of ancestry

F. Micheli, F. Lopera, I. Mata, 2017, npj Parkinson's Disease.

PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent

F. Lopera, M. Jimenez-Del-Rio, C. Velez-Pardo, 2023, International journal of molecular sciences.

Elevated cerebrospinal fluid amyloid-Beta42 levels in young adults at genetic risk for early-onset alzheimer's disease

A. Fagan, A. Shah, A. Fleisher, 2011, Alzheimer's & Dementia.

iPSCs-derived nerve-like cells from familial Alzheimer’s disease PSEN 1 E280A reveal increased amyloid-beta levels and loss of the Y chromosome

K. Kosik, F. Lopera, M. Jimenez-Del-Rio, 2019, Neuroscience Letters.

Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism.

M. Jimenez-Del-Rio, C. Velez-Pardo, Leonardo Bonilla-Ramírez, 2013, Gene.

Life Span and Locomotor Activity Modification by Glucose and Polyphenols in Drosophila melanogaster Chronically Exposed to Oxidative Stress-stimuli: Implications in Parkinson’s Disease

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2011, Neurochemical Research.

N-acetyl-cysteine blunts 6-hydroxydopamine- and l-buthionine-sulfoximine-induced apoptosis in human mesenchymal stromal cells

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2019, Molecular Biology Reports.

DNA Damage does not Correlate with Amyloid-beta-Plaques and Neurofibrillary Tangles in Familial Alzheimer's Disease Presenilin-1 [E280A] Mutation.

F. Lopera, C. Velez-Pardo, M. Jiménez Del Río, 2000, Journal of Alzheimer's disease : JAD.

Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2023, International journal of molecular sciences.

LRRK2 Knockout Confers Resistance in HEK-293 Cells to Rotenone-Induced Oxidative Stress, Mitochondrial Damage, and Apoptosis

M. Jimenez-Del-Rio, C. Velez-Pardo, Diana Quintero-Espinosa, 2023, International journal of molecular sciences.

TPEN/TPGS (T2) combo dramatically reduces Philadelphia chromosome-positive pro-lymphoblastic B leukemia in BALB/c mice

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2022, Medical Oncology.

Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson’s disease cohort

T. Thornton, F. Lopera, T. O’Connor, 2021, medRxiv.

Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2011, Cancer Cell International.

Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2023, Scientific reports.

Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson’s disease model

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2013, Genetics and molecular biology.

Cannabidiol Protects Dopaminergic-like Neurons against Paraquat- and Maneb-Induced Cell Death through Safeguarding DJ-1CYS106 and Caspase 3 Independently of Cannabinoid Receptors: Relevance in Parkinson's Disease.

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2023, ACS chemical neuroscience.

X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson’s Disease

T. Thornton, F. Lopera, T. O’Connor, 2023, Movement disorders : official journal of the Movement Disorder Society.

Molecular mechanism of monoamine toxicity in Parkinson's disease: hypothetical cell death model.

C. Velez-Pardo, M. Jiménez Del Río, M. J. Rio, 2000, Medical hypotheses.

Melatonin Increases Life Span, Restores the Locomotor Activity, and Reduces Lipid Peroxidation (LPO) in Transgenic Knockdown Parkin Drosophila melanogaster Exposed to Paraquat or Paraquat/Iron

M. Jimenez-Del-Rio, C. Velez-Pardo, H. Ortega-Arellano, 2021, Neurotoxicity Research.

Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster

M. Jimenez-Del-Rio, C. Velez-Pardo, D. A. Martinez-Perez, 2018, Neurotoxicity research.

Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun.

C. Velez-Pardo, M. Jiménez Del Río, G. G. Ospina, 2002, Neurotoxicology.

Correction to: Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster

M. Jimenez-Del-Rio, C. Velez-Pardo, D. A. Martinez-Perez, 2018, Neurotoxicity Research.

Oxidative Stress in Parkinson's Disease

M. Jimenez-Del-Rio, C. Velez-Pardo, 2018 .

Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K-dependent mechanisms: role of NF-kappaB and p53.

C. Velez-Pardo, M. J. Del Rio, 2006, Medicinal chemistry.

High Yield of Functional Dopamine-like Neurons Obtained in NeuroForsk 2.0 Medium to Study Acute and Chronic Rotenone Effects on Oxidative Stress, Autophagy, and Apoptosis

C. Velez-Pardo, D. Quintero-Espinosa, Marlene Jimenez-Del-Rio, 2023, International journal of molecular sciences.

Parkinson's Disease Gene Screening in Familial Cases from Central and South America.

M. Jimenez-Del-Rio, C. Velez-Pardo, C. Zabetian, 2024, Movement disorders : official journal of the Movement Disorder Society.

The GBA1 K198E Variant Is Associated with Suppression of Glucocerebrosidase Activity, Autophagy Impairment, Oxidative Stress, Mitochondrial Damage, and Apoptosis in Skin Fibroblasts

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2024, International journal of molecular sciences.

Sildenafil Reverses the Neuropathological Alzheimer's Disease Phenotype in Cholinergic-Like Neurons Carrying the Presenilin 1 E280A Mutation.

M. Jimenez-Del-Rio, C. Velez-Pardo, Daniela Giraldo-Berrio, 2024, Journal of Alzheimer's disease : JAD.

Combination of Tramiprosate, Curcumin, and SP600125 Reduces the Neuropathological Phenotype in Familial Alzheimer Disease PSEN1 I416T Cholinergic-like Neurons

M. Jimenez-Del-Rio, C. Velez-Pardo, Nicolas Gomez-Sequeda, 2024, International journal of molecular sciences.

Minocycline mitigates Aβ and TAU pathology, neuronal dysfunction, and death in the PSEN1 E280A cholinergic-like neurons model of familial Alzheimer’s disease

M. Jimenez-Del-Rio, C. Velez-Pardo, Daniela Giraldo-Berrio, 2024, Neuropharmacology.

Rotenone Induces a Neuropathological Phenotype in Cholinergic-like Neurons Resembling Parkinson’s Disease Dementia (PDD)

M. Jimenez-Del-Rio, C. Velez-Pardo, Miguel Mendivil-Perez, 2024, Neurotoxicity research.