S. Lam

发表

Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater

B. Ching, Xiu L. Chen, Jing H. A. Yong, 2013, Front. Physiol..

Transcriptome Analysis of Zebrafish Embryogenesis Using Microarrays

Z. Gong, K. Govindarajan, E. Liu, 2005, PLoS genetics.

Differential transcriptomic analyses revealed genes and signaling pathways involved in iono-osmoregulation and cellular remodeling in the gills of euryhaline Mozambique tilapia, Oreochromis mossambicus

W. Sung, S. Lam, Y. Ip, 2014, BMC Genomics.

Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression

Huiqing Zhan, Zhiyuan Gong, Yan Tong, 2006, Nature Biotechnology.

Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study

Z. Gong, S. Lam, Chunsheng Liu, 2013, PloS one.

Molecular Characterization of Branchial aquaporin 1aa and Effects of Seawater Acclimation, Emersion or Ammonia Exposure on Its mRNA Expression in the Gills, Gut, Kidney and Skin of the Freshwater Climbing Perch, Anabas testudineus

B. Ching, Xiu L. Chen, W. P. Wong, 2013, PloS one.

Metabolomics of developing zebrafish embryos using gas chromatography- and liquid chromatography-mass spectrometry.

Z. Gong, S. Lam, Fengguo Xu, 2013, Molecular Biosystems.

Toxicogenomic and Phenotypic Analyses of Bisphenol-A Early-Life Exposure Toxicity in Zebrafish

Z. Gong, C. Ung, S. Lam, 2011, PloS one.

An integrated approach with the zebrafish model for biomonitoring of municipal wastewater effluent and receiving waters.

Z. Gong, Qiyu Chen, S. Lam, 2018, Water research.

Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study.

Z. Gong, S. Lam, T. J. Lam, 2004, Developmental and comparative immunology.

Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses.

Z. Gong, C. Ung, S. Lam, 2013, Biochimica et biophysica acta.

Potential Applications of Transgenic Fish to Environmental Monitoring and Toxicology

Z. Gong, S. Lam, Hwee Boon Grace Ng, 2011 .

Na+/H+ Exchanger 3 Is Expressed in Two Distinct Types of Ionocyte, and Probably Augments Ammonia Excretion in One of Them, in the Gills of the Climbing Perch Exposed to Seawater

Xiu L. Chen, W. P. Wong, S. Lam, 2017, Front. Physiol..

A Metabonomic Investigation of Zebrafish Exposed to Bisphenol A

S. Lam, Z. Gong, C. Ong, 2010, 2010 4th International Conference on Bioinformatics and Biomedical Engineering.

Evidence for the involvement of branchial Vacuolar-type H+-ATPase in the acidification of the external medium by the West African lungfish, Protopterus annectens, exposed to ammonia-loading conditions.

W. P. Wong, S. Lam, S. Chew, 2022, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Roles of three branchial Na(+)-K(+)-ATPase α-subunit isoforms in freshwater adaptation, seawater acclimation, and active ammonia excretion in Anabas testudineus.

Xiu L. Chen, Jonathan M. Wilson, E. Sim, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Effects of thyroid hormone on the development of immune system in zebrafish.

S. Lam, Y. M. Sin, Z. Gong, 2005, General and comparative endocrinology.

Cystic fibrosis transmembrane conductance regulator in the gills of the climbing perch, Anabas testudineus, is involved in both hypoosmotic regulation during seawater acclimation and active ammonia excretion during ammonia exposure

Xiu L. Chen, Jonathan M. Wilson, W. P. Wong, 2012, Journal of Comparative Physiology B.

Molecular characterization and light-dependent expression of glycerol facilitator (GlpF) in coccoid Symbiodiniaceae dinoflagellates of the giant clam Tridacna squamosa

S. Lam, S. Chew, Y. Ip, 2022, Gene Reports.

Genome-Wide Identification of Molecular Pathways and Biomarkers in Response to Arsenic Exposure in Zebrafish Liver

Z. Gong, S. Lam, Hongyan Xu, 2013, PloS one.

Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver.

Z. Gong, E. Liu, L. Miller, 2006, Physiological genomics.

Both seawater acclimation and environmental ammonia exposure lead to increases in mRNA expression and protein abundance of Na+:K+:2Cl− cotransporter in the gills of the climbing perch, Anabas testudineus

W. P. Wong, S. Lam, S. Chew, 2012, Journal of Comparative Physiology B.

Molecular characterization of three Rhesus glycoproteins from the gills of the African lungfish, Protopterus annectens, and effects of aestivation on their mRNA expression levels and protein abundance

B. Ching, Xiu L. Chen, K. Hiong, 2017, PloS one.

Aestivation Induces Changes in the mRNA Expression Levels and Protein Abundance of Two Isoforms of Urea Transporters in the Gills of the African Lungfish, Protopterus annectens

B. Ching, Xiu L. Chen, K. Hiong, 2017, Frontiers in physiology.

An Investigation of the Bioactivation Potential and Metabolism Profile of Zebrafish versus Human

C. Yap, S. Lam, E. Chan, 2012, Journal of biomolecular screening.

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

Sinnakaruppan Mathavan, Guillaume Bourque, Thomas Lufkin, 2011, BMC Medical Genomics.

Transcriptomic Analyses of Sexual Dimorphism of the Zebrafish Liver and the Effect of Sex Hormones

Z. Gong, S. Lam, Weiling Zheng, 2013, PloS one.

Incorporating zebrafish omics into chemical biology and toxicology.

Z. Gong, C. Ung, S. Lam, 2010, Zebrafish.

Comparative transcriptome analyses revealed conserved biological and transcription factor target modules between the zebrafish and human tumors.

Z. Gong, C. Ung, S. Lam, 2009, Zebrafish.

Inverted Expression Profiles of Sex-Biased Genes in Response to Toxicant Perturbations and Diseases

Z. Gong, Hu Li, C. Ung, 2013, PloS one.

Modeling Liver Cancer Using Zebrafish: A Comparative Oncogenomics Approach

Z. Gong, S. Lam, 2006, Cell cycle.

A high level of liver-specific expression of oncogenic KrasV12 drives robust liver tumorigenesis in transgenic zebrafish

Z. Gong, S. Lam, A. Emelyanov, 2011, Disease Models & Mechanisms.

Molecular cloning of zebrafish and medaka vitellogenin genes and comparison of their expression in response to 17beta-estradiol.

Z. Gong, S. Lam, Yan Tong, 2004, Gene.

Development of estrogen-responsive transgenic medaka for environmental monitoring of endocrine disrupters.

Zhiqiang Zeng, Zhiyuan Gong, Yan Tong, 2005, Environmental science & technology.

Expression of Key Ion Transporters in the Gill and Esophageal-Gastrointestinal Tract of Euryhaline Mozambique Tilapia Oreochromis mossambicus Acclimated to Fresh Water, Seawater and Hypersaline Water

Jonathan M. Wilson, S. Lam, Y. Ip, 2014, PloS one.

RNA sequencing, de novo assembly and differential analysis of the gill transcriptome of freshwater climbing perch Anabas testudineus after 6 days of seawater exposure.

Xiu L. Chen, S. Lam, Y. Ip, 2018, Journal of fish biology.

Ammonia exposure affects the mRNA and protein expression levels of certain Rhesus glycoproteins in the gills of climbing perch

Xiu L. Chen, W. P. Wong, S. Lam, 2017, Journal of Experimental Biology.

The Zebrafish Model for Liver Carcinogenesis

Z. Gong, Huiqing Zhan, S. Lam, 2010 .

Morphological and molecular evidence for functional organization along the rostrocaudal axis of the adult zebrafish intestine

Z. Gong, P. Matsudaira, S. Lam, 2010, BMC Genomics.

Morphological and molecular evidence for functional organization along the rostrocaudal axis of the adult zebrafish

Z. Gong, P. Matsudaira, S. Lam, 2010 .

Glucocorticoid activity detected by in vivo zebrafish assay and in vitro glucocorticoid receptor bioassay at environmental relevant concentrations.

Z. Gong, Qiyu Chen, S. Lam, 2016, Chemosphere.

Metabolomic Characterizations of Liver Injury Caused by Acute Arsenic Toxicity in Zebrafish

Z. Gong, S. Lam, E. Chan, 2016, PloS one.

Existence of Inverted Profile in Chemically Responsive Molecular Pathways in the Zebrafish Liver

Z. Gong, Hu Li, C. Ung, 2011, PloS one.

Fish as a Model for Human Disease

Z. Gong, S. Lam, 2010 .

Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

Sinnakaruppan Mathavan, Choong Yong Ung, Zhiyuan Gong, 2010, BMC Genomics.

Zebrafish spotted-microarray for genome-wide expression profiling experiments: data acquisition and analysis.

Z. Gong, S. Lam, R. Krishna Murthy Karuturi, 2009, Methods in molecular biology.

Zebrafish spotted-microarray for genome-wide expression profiling experiments. Part I: array printing and hybridization.

Z. Gong, S. Lam, Sinnakarupan Mathavan, 2009, Methods in molecular biology.

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology

R. Krishna Murthy Karuturi, Edison T. Liu, Vinsensius B. Vega, 2008, PLoS genetics.

Super Resolution Microscopy Reveals that Caveolin-1 Is Required for Spatial Organization of CRFB1 and Subsequent Antiviral Signaling in Zebrafish

Z. Gong, S. Hess, T. Gould, 2013, PloS one.

Common deregulated gene expression profiles and morphological changes in developing zebrafish larvae exposed to environmental-relevant high to low concentrations of glucocorticoids.

Zhiyuan Gong, Shane A Snyder, Eric Chun Yong Chan, 2017, Chemosphere.

Zebrafish for drug toxicity screening: bridging the in vitro cell-based models and in vivo mammalian models

Zhiyuan Gong, Eric Chun Yong Chan, Hui Ting Chng, 2011, Expert opinion on drug metabolism & toxicology.

Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: histological, gene set enrichment and expression analyses.

Z. Gong, C. Ung, S. Lam, 2012, Biochimica et biophysica acta.

Morphologic transformation of the thymus in developing zebrafish

Z. Gong, S. Lam, Zilong Wen, 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

Classroom Observation for the Professional Development of Myanmar University Lecturers in a Singapore Cross-Cultural Context: Perception of Abilities and Learning Based on ‘Nine Events of Instruction’

S. Lam, 2018, European Journal of Social Science Education and Research.

Environmental OMICS: Current Status and Future Directions

Z. Gong, Leming Shi, N. Mei, 2013 .

Tilapia and human CLIC2 structures are highly conserved.

S. Lam, K. Swaminathan, E. Y. Lui, 2018, Biochemical and biophysical research communications.

Proteomic Analysis of Zebrafish (Danio rerio) After Chemical Exposure.

Z. Gong, S. Lam, Q. Lin, 2018, Methods in molecular biology.

Toxicogenomic Analysis Suggests Chemical-Induced Sexual Dimorphism in the Expression of Metabolic Genes in Zebrafish Liver

Z. Gong, C. Ung, Jing Ma, 2012, PloS one.

RNA-Sequencing Analysis of TCDD-Induced Responses in Zebrafish Liver Reveals High Relatedness to In Vivo Mammalian Models and Conserved Biological Pathways

Z. Gong, S. Lam, Weiling Zheng, 2013, PloS one.

W. Sung, S. Lam, Y. Ip, 2014, BMC Genomics.

Molecular Characterization of Aquaporin 1 and Aquaporin 3 from the Gills of the African Lungfish, Protopterus annectens, and Changes in Their Branchial mRNA Expression Levels and Protein Abundance during Three Phases of Aestivation

B. Ching, Xiu L. Chen, K. Hiong, 2016, Front. Physiol..

W. P. Wong, S. Lam, S. Chew, 2011, Journal of Comparative Physiology B.

RNA sequencing, de novo assembly and differential analysis of the gill transcriptome of freshwater climbing perch Anabas testudineus after 6 days of seawater exposure.

Xiu L. Chen, S. Lam, Y. Ip, 2018, Journal of fish biology.