Yihua Chen

Mingyao Liu, Jian Luo, Yihua Chen, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane.

Mingyao Liu, Z. Yi, Yihua Chen, 2020, European journal of medicinal chemistry.

In vivo target protein degradation induced by PROTACs based on E3 ligase DCAF15

Mingyao Liu, Dali Li, Yihua Chen, 2020, Signal Transduction and Targeted Therapy.

Discovery of potent ureido tetrahydrocarbazole derivatives for cancer treatments through targeting tumor-associated macrophages.

Mingyao Liu, Yihua Chen, Rong-hong Zhang, 2019, European journal of medicinal chemistry.

Discovery of 1,5-diaryl-1,2,4-triazole derivatives as myoferlin inhibitors and their antitumor effects in pancreatic cancer.

Yuan He, Z. Yi, Yihua Chen, 2022, Future medicinal chemistry.

Discovery of a Highly Potent and Orally Bioavailable STAT3 Dual Phosphorylation Inhibitor for Pancreatic Cancer Treatment.

Z. Yi, Yihua Chen, Yue Sun, 2022, Journal of medicinal chemistry.

Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and Metastasis.

Tao Zhang, Mingyao Liu, Z. Yi, 2022, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.

Mingyao Liu, Xiufeng Pang, Z. Yi, 2014, Journal of medicinal chemistry.

A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression

Mingyao Liu, Yuan He, Z. Yi, 2021, Clinical and translational medicine.

Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin.

Mingyao Liu, Yuan He, Z. Yi, 2019, Journal of medicinal chemistry.

Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor‐2

Mingyao Liu, Z. Yi, Yanmin Dong, 2012, British journal of pharmacology.

A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis viaFAK pathway

Tao Zhang, Mingyao Liu, Z. Yi, 2014, Journal of cellular and molecular medicine.

Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents.

Cai-Guang Yang, Mingyao Liu, Yihua Chen, 2019, European journal of medicinal chemistry.

A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer

Mingyao Liu, Yuan He, Z. Yi, 2018, Nature Communications.

A novel methuosis inducer DZ-514 possesses antitumor activity via activation of ROS-MKK4-p38 axis in triple negative breast cancer.

Yihua Chen, Ceshi Chen, Y. Zhang, 2023, Cancer letters.

Recent Advances of Small Molecular Regulators Targeting G Protein-Coupled Receptors Family for Oncology Immunotherapy.

Mingyao Liu, Yihua Chen, Wenbo Zhou, 2019, Current topics in medicinal chemistry.

Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.

Mingyao Liu, Xiufeng Pang, Z. Yi, 2020, Journal of medicinal chemistry.

Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down‐regulating EGFR expression

Mingyao Liu, Yuan He, Z. Yi, 2015, British journal of pharmacology.

Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways

Zhen-ran Jiang, Z. Yi, Yanmin Dong, 2016, Scientific Reports.

B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell Lymphomas.

Yihua Chen, Weikai Guo, Bo Liu, 2022, Journal of medicinal chemistry.

The promising combination therapy strategy for overcoming resistance to histone deacetylase inhibitors in diffuse large B‐cell lymphoma

Yihua Chen, Haixiang Pei, 2022, Clinical and Translational Discovery.

Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1.

Jian Luo, Tieliu Shi, Zhengfeng Yang, 2013, Journal of the National Cancer Institute.

A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.

Mingyao Liu, Z. Yi, Yihua Chen, 2016, Organic & biomolecular chemistry.

Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion

Tao Zhang, Mingyao Liu, Z. Yi, 2012, Breast Cancer Research and Treatment.

Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer

Mingyao Liu, Yuan He, Z. Yi, 2018, EBioMedicine.

Antitumor Action of a Novel Histone Deacetylase Inhibitor, YF479, in Breast Cancer

Mingyao Liu, Z. Yi, F. Dai, 2014, Neoplasia.

Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2‐mediated PI3K/Akt/mTOR signaling pathway

Mingyao Liu, Xiufeng Pang, Z. Yi, 2011, Cancer science.

Development of hydroxamate-based histone deacetylase inhibitors of bis-substituted aromatic amides with antitumor activities.

Yihua Chen, Hua Zhang, N. Zhao, 2019, MedChemComm.

Next-generation of selective histone deacetylase inhibitors

Yihua Chen, Feifei Yang, N. Zhao, 2019, RSC advances.

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

Tao Zhang, Mingyao Liu, Xiufeng Pang, 2014, Journal of medicinal chemistry.

Synthesis and biological evaluation of thiophene-based hydroxamate derivatives as HDACis with antitumor activities.

Yihua Chen, Hua Zhang, N. Zhao, 2020, Future medicinal chemistry.

A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling

Mingyao Liu, Yongrui Liu, Yuan He, 2017, Science China Life Sciences.

Small-Molecule Modulators Targeting SHP2 for Cancer Therapy.

Yihua Chen, Yuzhan Li, Dazhao Mi, 2022, Anti-cancer agents in medicinal chemistry.

Small molecule PROTACs: an emerging technology for targeted therapy in drug discovery

Yihua Chen, Haixiang Pei, Yangrui Peng, 2019, RSC advances.

Discovery of a Novel Potent STAT3 Inhibitor HP590 with Dual p-Tyr705/Ser727 Inhibitory Activity for Gastric Cancer Treatment.

Mingyao Liu, Z. Yi, Yihua Chen, 2022, Journal of medicinal chemistry.

Inhibition of STAT3 Signaling Pathway by Nitidine Chloride Suppressed the Angiogenesis and Growth of Human Gastric Cancer

Mingyao Liu, Xiufeng Pang, Z. Yi, 2011, Molecular Cancer Therapeutics.

Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway.

Yihua Chen, Qianjun Chen, Jun Ling, 2023, Cancer letters.

An Emerging Therapeutic Approach by Targeting Myoferlin (MYOF) for Malignant Tumors.

Yihua Chen, Yangrui Peng, Haijun Gu, 2020, Current topics in medicinal chemistry.

LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity

Mingyao Liu, Yuan He, Yundong He, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Therapeutic Discovery Inhibition of STAT 3 Signaling Pathway by Nitidine Chloride Suppressed the Angiogenesis and Growth of Human Gastric Cancer

Mingyao Liu, Xiufeng Pang, Z. Yi, 2012 .

Corrigendum to "Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents" [Eur. J. Med. Chem. 162 (162) (2019) 203-211].

Cai-Guang Yang, Mingyao Liu, Yihua Chen, 2019, European journal of medicinal chemistry.

Kiss1/Gpr54 Prevents Bone Loss through Src Dephosphorylation by Dusp18 in Osteoclasts

Mingyao Liu, Jian Luo, Wenyi Wei, 2021 .

Inhibition of CDC25B With WG-391D Impedes the Tumorigenesis of Ovarian Cancer

P. Zhan, Yihua Chen, Yu'ning Song, 2019, Front. Oncol..

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

Mingyao Liu, Z. Yi, Yihua Chen, 2015, European journal of medicinal chemistry.

Novel orthodiphenyl five-member N-heteroaromatic compounds as potent anticancer cell agents

Z. Yi, Yihua Chen, Shijia Hu, 2022, Medicinal Chemistry Research.

Preclinical characterization of WB737, a potent and selective STAT3 inhibitor, in natural killer/T‐cell lymphoma

C. Ong, B. Teh, Mingyao Liu, 2023, MedComm.

A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia.

Ming-Yu Liu, Z. Yi, Yihua Chen, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

Tao Zhang, Mingyao Liu, Xiufeng Pang, 2014, Journal of medicinal chemistry.

Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down‐regulating EGFR expression

Mingyao Liu, Yuan He, F. Dai, 2015, British journal of pharmacology.

A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.

Mingyao Liu, Yihua Chen, Feifei Yang, 2016, Organic & biomolecular chemistry.

Selectively targeting STAT3 using a small molecule inhibitor is a potential therapeutic strategy for pancreatic cancer.

Mingyao Liu, Yihua Chen, Zhenliang Sun, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

Discovery of a Potent and Oral Available Complex I OXPHOS Inhibitor That Abrogates Tumor Growth and Circumvents MEKi Resistance.

Mingyao Liu, Xiufeng Pang, Yihua Chen, 2023, Journal of medicinal chemistry.

LG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia

F. Lv, Z. Yi, Yihua Chen, 2016, Leukemia.