C. Josenhans

发表

Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53.

R. Sompallae, Nina Coombs, Patrick Olbermann, 2011, International Journal of Medical Microbiology.

Bacterial energy taxis: a global strategy?

Christine Josenhans, C. Josenhans, Tobias Schweinitzer, 2010, Archives of Microbiology.

Protein Activity Sensing in Bacteria in Regulating Metabolism and Motility

C. Josenhans, A. Alvarado, Wiebke Behrens, 2020, Frontiers in Microbiology.

A tale of two machines: a review of the BLAST meeting, Tucson, AZ, 20–24 January 2013

C. V. Rao, K. Jung, C. Josenhans, 2014, Molecular microbiology.

Green fluorescent protein as a novel marker and reporter system in Helicobacter sp.

C. Josenhans, S. Friedrich, S. Suerbaum, 1998, FEMS microbiology letters.

Pathogenomics of helicobacter.

T. Meyer, C. Josenhans, D. Beier, 2007, International journal of medical microbiology : IJMM.

A Nod toward understanding Crohn's pathology

M. Hornef, C. Josenhans, 2011, Nature Network Boston.

Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen

J. Parkhill, S. Bentley, K. Hardie, 2010, BMC Genomics.

Crosstalk between microbiota, pathogens and the innate immune responses.

C. Josenhans, C. Günther, J. Wehkamp, 2016, International journal of medical microbiology : IJMM.

YscP, a Yersinia protein required for Yop secretion that is surface exposed, and released in low Ca2+

C. Josenhans, I. Lambermont, G. Cornelis, 2000, Molecular microbiology.

Utilization of host‐derived cysteine‐containing peptides overcomes the restricted sulphur metabolism of Campylobacter jejuni

D. Schomburg, W. Eisenreich, C. Josenhans, 2014, Molecular microbiology.

The complex methylome of the human gastric pathogen Helicobacter pylori

J. Korlach, Khai Luong, R. Roberts, 2013, Nucleic acids research.

Rapid Loss of Motility of Helicobacter pylori in the Gastric Lumen In Vivo

C. Josenhans, S. Friedrich, S. Suerbaum, 2005, Infection and Immunity.

Relevance of Campylobacter to public health--the need for a One Health approach.

L. Kreienbrock, C. Josenhans, L. Wieler, 2014, International journal of medical microbiology : IJMM.

Functional Characterization and Mutagenesis of the Proposed Behavioral Sensor TlpD of Helicobacter pylori

C. Josenhans, Tobias Schweinitzer, S. Suerbaum, 2008, Journal of bacteriology.

C-Type Lectin Receptor (CLR)–Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates

C. Josenhans, B. Lepenies, João T. Monteiro, 2018, Front. Immunol..

How bacterial pathogens of the gastrointestinal tract use the mucosal glyco-code to harness mucus and microbiota: New ways to study an ancient bag of tricks.

C. Josenhans, L. Elling, H. Schmidt, 2020, International journal of medical microbiology : IJMM.

Helicobacter pylori colonization critically depends on postprandial gastric conditions

C. Josenhans, S. Suerbaum, S. Schreiber, 2012, Scientific Reports.

Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other Campylobacterales

C. Josenhans, K. Tedin, S. Rautenschlein, 2015, mSphere.

Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species

A. Labigne, C. Josenhans, S. Suerbaum, 1995, Journal of bacteriology.

A combined case-control and molecular source attribution study of human Campylobacter infections in Germany, 2011–2014

X. Didelot, K. Stingl, C. Josenhans, 2017, Scientific Reports.

Biochemical characterization of the Helicobacter pylori Cag Type 4 Secretion System protein CagN and its interaction partner CagM.

Nina Coombs, C. Josenhans, L. Terradot, 2018, International journal of medical microbiology : IJMM.

ADP‐heptose enables Helicobacter pylori to exploit macrophages as a survival niche by suppressing antigen‐presenting HLA‐II expression

C. Josenhans, M. D’Elios, M. Bernard, 2021, FEBS letters.

The neuA/flmD gene cluster of Helicobacter pylori is involved in flagellar biosynthesis and flagellin glycosylation.

C. Josenhans, S. Friedrich, S. Suerbaum, 2002, FEMS microbiology letters.

Helicobacter pylori lipopolysaccharide interacts with TFF1 in a pH-dependent manner.

C. Josenhans, R. O'Kennedy, S. Suerbaum, 2008, Gastroenterology.

The spatial orientation of Helicobacter pylori in the gastric mucus.

C. Josenhans, S. Suerbaum, P. Scheid, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Gastric antibacterial efficiency is different for pepsin A and C

C. Josenhans, S. Suerbaum, S. Gatermann, 2005, Archives of Microbiology.

In Vivo Distribution of Helicobacter felis in the Gastric Mucus of the Mouse: Experimental Method and Results

C. Josenhans, S. Suerbaum, P. Scheid, 1999, Infection and Immunity.

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

Nina Coombs, C. Josenhans, Saskia C Stein, 2017, PLoS pathogens.

Virulence factors of Helicobacter pylori: implications for vaccine development.

C. Josenhans, S. Suerbaum, S. Suerbaum, 1999, Molecular medicine today.

Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. pylori flaA- and flaB-negative mutants by electroporation-mediated allelic exchange

A. Labigne, C. Josenhans, S. Suerbaum, 1993, Journal of bacteriology.

Role of Energy Sensor TlpD of Helicobacter pylori in Gerbil Colonization and Genome Analyses after Adaptation in the Gerbil

X. Didelot, C. Josenhans, Tobias Schweinitzer, 2013, Infection and Immunity.

Genome Sequence of Helicobacter pylori hpEurope Strain N6

C. Josenhans, Wiebke Behrens, S. Suerbaum, 2012, Journal of bacteriology.

The Helicobacter pylori Anti-Sigma Factor FlgM Is Predominantly Cytoplasmic and Cooperates with the Flagellar Basal Body Protein FlhA

K. Hughes, C. Josenhans, J. McMurry, 2009, Journal of bacteriology.

Genomic Changes during Chronic Helicobacter pylori Infection

D. Falush, C. Josenhans, J. Fox, 2006, Journal of bacteriology.

Cloning and characterization of the Helicobacter pylori flbA gene, which codes for a membrane protein involved in coordinated expression of flagellar genes

A. Schmitz, C. Josenhans, S. Suerbaum, 1997, Journal of bacteriology.

Helicobacter hepaticus Induces an Inflammatory Response in Primary Human Hepatocytes

H. Schrem, C. Josenhans, J. Klempnauer, 2014, PloS one.

Cloning and allelic exchange mutagenesis of two flagellin genes of Helicobacter felis

A. Labigne, C. Josenhans, S. Suerbaum, 1999, Molecular microbiology.

Identification of Antimotilins, Novel Inhibitors of Helicobacter pylori Flagellar Motility That Inhibit Stomach Colonization in a Mouse Model

A. Gruber, Nina Coombs, C. Josenhans, 2022, mBio.

Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae

A. Labigne, C. Josenhans, S. Suerbaum, 1995, Infection and immunity.

Helicobacter hepaticus HHGI1 is a pathogenicity island associated with typhlocolitis in B6.129-IL10 tm1Cgn mice.

C. Josenhans, J. Fox, Zeli Shen, 2008, Microbes and infection.

Adherence of Isogenic Flagellum-Negative Mutants ofHelicobacter pylori and Helicobacter mustelae to Human and Ferret Gastric Epithelial Cells

C. Josenhans, S. Suerbaum, B. Drumm, 2000, Infection and Immunity.

Flagellar and global gene regulation in Helicobacter pylori modulated by changes in DNA supercoiling.

C. Josenhans, S. Suerbaum, K. Drlica, 2007, International journal of medical microbiology : IJMM.

Infection of the ferret stomach by isogenic flagellar mutant strains of Helicobacter mustelae

C. Josenhans, J. Fox, R. Marini, 1997, Infection and immunity.

Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome

K. Hughes, B. Drescher, C. Josenhans, 2002, Molecular microbiology.

Bacterial genomics: seven years on.

C. Josenhans, S. Suerbaum, M. Frosch, 2002, Trends in microbiology.

Biochemical studies of Helicobacter mustelae fatty acid composition and flagella

C. Josenhans, S. Suerbaum, W. Opferkuch, 1992, Infection and immunity.

The role of motility as a virulence factor in bacteria.

Christine Josenhans, C. Josenhans, S. Suerbaum, 2002, International journal of medical microbiology : IJMM.

A Global Overview of the Genetic and Functional Diversity in the Helicobacter pylori cag Pathogenicity Island

M. Achtman, M. Uhr, Patrick Olbermann, 2010, PLoS genetics.

Helicobacter pylori evolution and phenotypic diversification in a changing host

C. Josenhans, S. Suerbaum, 2007, Nature Reviews Microbiology.

Helicobacter pylori genome evolution during human infection

D. Falush, R. Reinhardt, T. Meyer, 2011, Proceedings of the National Academy of Sciences.

The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models

C. Josenhans, S. Suerbaum, S. Nell, 2010, Nature Reviews Microbiology.

Characterization of the Pilin Ortholog of the Helicobacter pylori Type IV cag Pathogenicity Apparatus, a Surface-Associated Protein Expressed during Infection

M. Achtman, Patrick Olbermann, C. Josenhans, 2006, Journal of bacteriology.

Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition

C. Josenhans, K. Tedin, Melanie M. Brinkmann, 2018, Scientific Reports.

Endotoxicity of lipopolysaccharide as a determinant of T-cell-mediated colitis induction in mice.

P. Adam, A. Gruber, D. Huson, 2014, Gastroenterology.

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

C. Josenhans, M. Henriksson, B. Stenerlöw, 2010, PloS one.

Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori

C. Josenhans, M. Albanese, Saskia C Stein, 2021, Frontiers in Immunology.

In Vivo Genome and Methylome Adaptation of cag-Negative Helicobacter pylori during Experimental Human Infection

T. Meyer, C. Josenhans, J. Overmann, 2020, mBio.

The core genome m5C methyltransferase JHP1050 (M.Hpy99III) plays an important role in orchestrating gene expression in Helicobacter pylori

C. Josenhans, S. Suerbaum, J. Krebes, 2018, bioRxiv.

Localisation and protein-protein interactions of the Helicobacter pylori taxis sensor TlpD and their connection to metabolic functions

C. Josenhans, J. McMurry, Tobias Schweinitzer, 2016, Scientific Reports.

Dynamics of Lewis b Binding and Sequence Variation of the babA Adhesin Gene during Chronic Helicobacter pylori Infection in Humans

C. Josenhans, S. Suerbaum, Sandra Schwarz, 2014, mBio.

In Vivo Sequence Variation in HopZ, a Phase-Variable Outer Membrane Protein of Helicobacter pylori

T. Meyer, L. Engstrand, C. Josenhans, 2012, Infection and Immunity.

Helicobacter pylori and the innate immune system.

C. Josenhans, Sae-Kyung Lee, 2005, International journal of medical microbiology : IJMM.

Genome‐wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori

Ralph Schlapbach, Christoph Dehio, Michaela Dehio, 2004, Molecular microbiology.

Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5.

C. Josenhans, S. Suerbaum, S. Aizawa, 2003, Microbes and infection.

The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus

G. Nyakatura, P. Brandt, B. Drescher, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Growth phase-dependent and differential transcriptional control of flagellar genes in Helicobacter pylori.

C. Josenhans, S. Suerbaum, Fang Ye, 2002, Microbiology.

Switching of Flagellar Motility in Helicobacter pyloriby Reversible Length Variation of a Short Homopolymeric Sequence Repeat in fliP, a Gene Encoding a Basal Body Protein

Kathryn A. Eaton, Christine Josenhans, C. Josenhans, 2000, Infection and Immunity.

Expression and subcellular distribution of toll‐like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection

H. Müller-Hermelink, C. Josenhans, M. Andrulis, 2004, Clinical and experimental immunology.

Microbiome and Diseases: Pathogen Infection

C. Josenhans, G. Grassl, 2018 .

Role of the Helicobacter hepaticus Flagellar Sigma Factor FliA in Gene Regulation and Murine Colonization

C. Josenhans, Wiebke Behrens, J. Fox, 2008, Journal of bacteriology.

Hcp and VgrG1 are secreted components of the Helicobacter hepaticus type VI secretion system and VgrG1 increases the bacterial colitogenic potential

A. Gruber, C. Josenhans, S. Suerbaum, 2013, Cellular microbiology.

Downregulation of CXCR1 and CXCR2 Expression on Human Neutrophils by Helicobacter pylori: a New Pathomechanism in H. pylori Infection?

H. Müller-Hermelink, C. Josenhans, P. Rieckmann, 2004, Infection and Immunity.

Gastric Non-Helicobacter pylori Urease-Positive Staphylococcus epidermidis and Streptococcus salivarius Isolated from Humans Have Contrasting Effects on H. pylori-Associated Gastric Pathology and Host Immune Responses in a Murine Model of Gastric Cancer

L. Bravo, A. Sheh, R. Peek, 2022, mSphere.

Different gastric microbiota compositions in two human populations with high and low gastric cancer risk in Colombia

L. Bravo, R. Peek, C. Josenhans, 2016, Scientific Reports.

D. Schomburg, X. Didelot, M. Uhr, 2011, BMC Genomics.

Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells

H. Leonhardt, C. Josenhans, M. Griffioen, 2020, Frontiers in Immunology.

Chronic exposure to the cytolethal distending toxins of Gram‐negative bacteria promotes genomic instability and altered DNA damage response

M. Masucci, C. Josenhans, B. Stenerlöw, 2013, Cellular microbiology.

Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains

Patrick Olbermann, C. Josenhans, W. Fischer, 2016, Scientific Reports.

Mycobacterium smegmatis laminin‐binding glycoprotein shares epitopes with Mycobacterium tuberculosis heparin‐binding haemagglutinin

C. Locht, H. Drobecq, C. Josenhans, 2001, Molecular microbiology.

Colonization of gnotobiotic piglets by Helicobacter pylori deficient in two flagellin genes

C. Josenhans, S. Suerbaum, S. Krakowka, 1996, Infection and immunity.

Pathogenesis of Helicobacter pylori Infection

C. Josenhans, M. Bernard, 2014, Helicobacter.

Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells.

C. Josenhans, Saskia C Stein, Martina Hauke, 2023, Current opinion in immunology.

Intestinal Microbiota Composition of Interleukin-10 Deficient C57BL/6J Mice and Susceptibility to Helicobacter hepaticus-Induced Colitis

A. Gruber, C. Josenhans, J. Fox, 2013, PloS one.

Inhibitory Effect of Enterohepatic Helicobacter hepaticus on Innate Immune Responses of Mouse Intestinal Epithelial Cells

C. Josenhans, J. Fox, S. Suerbaum, 2007, Infection and Immunity.

Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition

C. Josenhans, K. Tedin, Melanie M. Brinkmann, 2018, Scientific Reports.

Chitinase A, a tightly regulated virulence factor of Salmonella enterica serovar Typhimurium, is actively secreted by a Type 10 Secretion System.

C. Josenhans, Martina Hauke, Larissa Faass, 2023, PLoS pathogens.

electroporation-mediated allelic exchange. pylori flaA- and flaB-negative mutants by flaB flagellin genes and construction of H. Helicobacter pylori and Helicobacter mustelae Cloning and genetic characterization of the

A. Labigne, C. Josenhans, S. Suerbaum, 2013 .

Cloning and Genetic Characterization of the Helicobacter pyloni and Helicobacter mustelae

A. Labigne, C. Josenhans, S. Suerbaum, 2022 .

Helicobacter pylori Modulates Heptose Metabolite Biosynthesis and Heptose-Dependent Innate Immune Host Cell Activation by Multiple Mechanisms

W. Eisenreich, H. Link, C. Josenhans, 2023, bioRxiv.

Different Helicobacter hepaticus Strains with Variable Genomic Content Induce Various Degrees of Hepatitis

C. Josenhans, J. Fox, Yan Feng, 2005, Infection and Immunity.

Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori.

C. Josenhans, Saskia C Stein, Martina Hauke, 2023, International journal of medical microbiology : IJMM.

Pathogenesis of Helicobacter pylori Infection

C. Josenhans, M. Bernard, 2014, Helicobacter.

Tu1288 - Co-Colonization of Helicobacter Pylori with Staphylococcus Epidermidis or Streptococcus Salivarius Differ in the Progression of Gastritis in Ins-Gas Mice

L. Bravo, C. Josenhans, J. Fox, 2018 .

Utilization of host‐derived cysteine‐containing peptides overcomes the restricted sulphur metabolism of Campylobacter jejuni

D. Schomburg, W. Eisenreich, C. Josenhans, 2014, Molecular microbiology.

A tale of two machines: a review of the BLAST meeting, Tucson, AZ, 20–24 January 2013

C. V. Rao, K. Jung, C. Josenhans, 2014, Molecular microbiology.

The Helicobacter pylori Anti-Sigma Factor FlgM Is Predominantly Cytoplasmic and Cooperates with the Flagellar Basal Body Protein FlhA

Jonathan L. McMurry, K. Hughes, C. Josenhans, 2009, Journal of bacteriology.

Helicobacter pylori lipopolysaccharide interacts with TFF1 in a pH-dependent manner.

C. Josenhans, S. Suerbaum, P. Leonard, 2008, Gastroenterology.

Virulence factors of Helicobacter pylori: implications for vaccine

C. Josenhans, 1999 .