A. Evdokiou

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Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

David F. Callen, David P. Lane, D. Lane, 2011, Oncotarget.

An overview of nanotoxicity and nanomedicine research: principles, progress and implications for cancer therapy.

A. Evdokiou, D. Losic, Ye Wang, 2015, Journal of materials chemistry. B.

3D printed titanium implants with nano-engineered surface titania nanotubes for localized drug delivery

Gagandeep Kaur, Dusan Losic, Ahmed ElMekawy, 2016 .

Calcium induces pro-anabolic effects on human primary osteoblasts associated with acquisition of mature osteocyte markers

A. Evdokiou, D. Findlay, G. Atkins, 2013, Molecular and Cellular Endocrinology.

Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts.

A. Evdokiou, P. Cowled, 1998, Experimental cell research.

Tumor‐suppressive activity of the growth arrest‐specific gene GAS1 in human tumor cell lines

A. Evdokiou, P. Cowled, 1998, International journal of cancer.

Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate.

A. Evdokiou, G. Young, P. Zalewski, 2000, Carcinogenesis.

Pro‐Inflammatory Cytokines TNF‐Related Weak Inducer of Apoptosis (TWEAK) and TNFα Induce the Mitogen‐Activated Protein Kinase (MAPK)‐Dependent Expression of Sclerostin in Human Osteoblasts

A. Evdokiou, T. Zheng, N. Fazzalari, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption

A. Evdokiou, D. Leach, V. Panagopoulos, 2017, Molecular and Cellular Endocrinology.

Expression of fibrillins and other microfibril-associated proteins in human bone and osteoblast-like cells.

A. Evdokiou, S. Kitahama, G. Atkins, 2000, Bone.

Enhanced Apoptosis of Soft Tissue Sarcoma Cells with Chemotherapy: A Potential New Approach Using Trail

A. Evdokiou, M. Clayer, G. Atkins, 2001, Journal of orthopaedic surgery.

Doxorubicin overcomes resistance to drozitumab by antagonizing Inhibitor of Apoptosis Proteins (IAPs).

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2014, Anticancer research.

Myeloma-Induced Alloreactive T Cells Arising in Myeloma-Infiltrated Bones Include Double-Positive CD8+CD4+ T Cells: Evidence from Myeloma-Bearing Mouse Model

A. Zannettino, Robert A. Smith, A. Evdokiou, 2011, The Journal of Immunology.

Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo

V. Ponomarev, A. Evdokiou, A. Zannettino, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Targeted Disruption of the CXCL12/CXCR4 Axis Inhibits Osteolysis in a Murine Model of Myeloma‐Associated Bone Loss

L. To, A. Evdokiou, Sally K. Martin, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Zoledronic Acid Inhibits Both the Osteolytic and Osteoblastic Components of Osteosarcoma Lesions in a Mouse Model

V. Ponomarev, A. Evdokiou, D. Findlay, 2009, Clinical Cancer Research.

Apomab, a fully human agonistic antibody to DR5, exhibits potent antitumor activity against primary and metastatic breast cancer

V. Ponomarev, A. Evdokiou, A. Zannettino, 2009, Molecular Cancer Therapeutics.

Anti-tumor and anti-osteolysis effects of the metronomic use of zoledronic acid in primary and metastatic breast cancer mouse models.

A. Evdokiou, K. Fung, G. Yue, 2013, Cancer letters.

Immune Regulation of Mammary Fibroblasts and the Impact of Mammographic Density

A. Evdokiou, W. Ingman, K. Britt, 2022, Journal of clinical medicine.

Myeloma-Induced Alloreactive T Cells

Dalia, A. Zannettino, A. Evdokiou, 2011 .

Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest.

A. Evdokiou, D. Findlay, G. Atkins, 1999, Molecular endocrinology.

Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.

A. Evdokiou, D. Leach, V. Panagopoulos, 2015, The international journal of biochemistry & cell biology.

Localization of the human growth arrest-specific gene (GAS1) to chromosome bands 9q21.3-q22, a region frequently deleted in myeloid malignancies.

A. Dobrovic, A. Evdokiou, G. Peters, 1993, Genomics.

RECK in osteosarcoma

David M. Thomas, P. Choong, A. Evdokiou, 2011, Cancer.

Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis.

A. Evdokiou, D. Findlay, A. Labrinidis, 2003, Bone.

Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation

H. Scher, P. Marks, L. Butler, 2007, Molecular Cancer Therapeutics.

The Effects of Vitamin E Analogues α-Tocopherol and γ-Tocotrienol on the Human Osteocyte Response to Ultra-high Molecular Weight Polyethylene Wear Particles

A. Evdokiou, A. Odysseos, L. B. Solomon, 2022, bioRxiv.

Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer.

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2017, Cancer letters.

Anticancer efficacy of the hypoxia‐activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2017, Cancer medicine.

SaOS2 Osteosarcoma Cells as an In Vitro Model for Studying the Transition of Human Osteoblasts to Osteocytes

A. Evdokiou, M. Prideaux, D. Findlay, 2014, Calcified Tissue International.

Human osteoblasts are resistant to Apo2L/TRAIL-mediated apoptosis.

A. Evdokiou, A. Zannettino, D. Haynes, 2002, Bone.

Evaluation of the combined use of metronomic zoledronic acid and Coriolus versicolor in intratibial breast cancer mouse model.

A. Evdokiou, G. Yue, J. K. Lee, 2017, Journal of ethnopharmacology.

Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2015, Cancer letters.

Zoledronic acid protects against osteosarcoma‐induced bone destruction but lacks efficacy against pulmonary metastases in a syngeneic rat model

A. Evdokiou, D. Findlay, A. Labrinidis, 2010, International Journal of Cancer.

Expression of Osteoclast Differentiation Signals by Stromal Elements of Giant Cell Tumors

A. Evdokiou, D. Haynes, S. Graves, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone.

S. Geary, A. Evdokiou, A. Zannettino, 2001, Bone.

Systematic in vitro nanotoxicity study on anodic alumina nanotubes with engineered aspect ratio: understanding nanotoxicity by a nanomaterial model.

A. Evdokiou, D. Losic, Ye Wang, 2015, Biomaterials.

Apo2l/Tumor necrosis factor-related apoptosis-inducing ligand prevents breast cancer-induced bone destruction in a mouse model.

B. Coventry, A. Evdokiou, D. Findlay, 2006, Cancer research.

Intracellular zinc depletion induces caspase activation and p21 Waf1/Cip1 cleavage in human epithelial cell lines.

A. Evdokiou, P. Zalewski, F. Chai, 2000, The Journal of infectious diseases.

Apo 2 L / TRAIL Inhibits Tumor Growth and Bone Destruction in aMurineModel of Multiple Myeloma

V. Ponomarev, A. Evdokiou, Sally K. Martin, 2009 .

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL

L. Butler, W. Tilley, A. Evdokiou, 2006, International journal of cancer.

Progressive resistance of BTK-143 osteosarcoma cells to Apo2L/TRAIL-induced apoptosis is mediated by acquisition of DcR2/TRAIL-R4 expression: resensitisation with chemotherapy

A. Evdokiou, G. Atkins, A. Labrinidis, 2003, British Journal of Cancer.

143 osteosarcoma cells to Apo 2 L / TRAIL-induced apoptosis is mediated by acquisition of DcR 2 / TRAIL-R 4 expression : resensitisation with chemotherapy

A. Evdokiou, A. Labrinidis, S. Hay, 2003 .

Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to apo2l/trail‐induced apoptosis

A. Evdokiou, M. Clayer, D. Findlay, 2002, International journal of cancer.

Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy.

M. Brown, K. Pishas, P. Neilsen, 2013, Oncology reports.

Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli

L. Bonewald, A. Evdokiou, M. Prideaux, 2015, Molecular and Cellular Endocrinology.

Facile synthesis of optical microcavities by a rationally designed anodization approach: tailoring photonic signals by nanopore structure.

A. Evdokiou, Fuyuan Ding, D. Losic, 2015, ACS applied materials & interfaces.

Rational Design of Ultra-Short Anodic Alumina Nanotubes by Short-Time Pulse Anodization

A. Evdokiou, D. Losic, Ye Wang, 2015 .

Assignment, by in situ hybridization, of the growth arrest-specific gene, Gas-1, to mouse chromosome 13, bands B3-C2.

A. Evdokiou, G. Webb, J. Ford, 1992, Genomics.

Loss of osteoclasts contributes to development of osteosarcoma pulmonary metastases.

A. Evdokiou, D. Rickwood, A. Guminski, 2010, Cancer research.

Sclerostin is a locally acting regulator of late‐osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE‐ASARM‐dependent mechanism

A. Evdokiou, D. Findlay, G. Atkins, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Mild Case of Autosomal Recessive Osteopetrosis Masquerading as the Dominant Form Involving Homozygous Deep Intronic Variations in the CLCN7 Gene

A. Evdokiou, Dongqing Yang, P. Roschger, 2022, Calcified Tissue International.

Sustained activation of Erk1/2 MAPK and cell growth suppression by the insert-negative, but not the insert-positive isoform of the human calcitonin receptor.

A. Evdokiou, D. Findlay, L. Raggatt, 2000, The Journal of endocrinology.

Cancer esearch oenvironment and Immunology s of Osteoclasts Contributes to Development of R eosarcoma Pulmonary Metastases

A. Evdokiou, D. Rickwood, A. Guminski, 2010 .

Chromosomal localization of the human urothelial "tetraspan" gene, UPK1B, to 3q13.3-q21 and detection of aTaqI polymorphism

A. Evdokiou, J. Finch, G. Webb, 1997 .

Peroxidase Enzymes Regulate Collagen Biosynthesis and Matrix Mineralization by Cultured Human Osteoblasts

A. Evdokiou, V. Panagopoulos, D. Findlay, 2016, Calcified Tissue International.

Sensitivity of fresh isolates of soft tissue sarcoma, osteosarcoma and giant cell tumour cells to Apo2L/TRAIL and doxorubicin.

A. Evdokiou, M. Clayer, S. Graves, 2004, International journal of oncology.

Peroxidase enzymes regulate collagen extracellular matrix biosynthesis.

A. Evdokiou, V. Panagopoulos, M. DeNichilo, 2015, The American journal of pathology.

Peroxidase Enzymes Regulate Collagen

A. Evdokiou, V. Panagopoulos, M. DeNichilo, 2015 .

The Effects of Vitamin E Analogues α-Tocopherol and γ-Tocotrienol on the Human Osteocyte Response to Ultra-high Molecular Weight Polyethylene Wear Particles

A. Evdokiou, A. Odysseos, L. B. Solomon, 2022, bioRxiv.

Bioinert Anodic Alumina Nanotubes for Targeting of Endoplasmic Reticulum Stress and Autophagic Signaling: A Combinatorial Nanotube-Based Drug Delivery System for Enhancing Cancer Therapy.

A. Evdokiou, D. Losic, Ye Wang, 2015, ACS applied materials & interfaces.

Plant-derived soybean peroxidase stimulates osteoblast collagen biosynthesis, matrix mineralization, and accelerates bone regeneration in a sheep model

A. Evdokiou, V. Panagopoulos, S. Gronthos, 2021, Bone reports.

RANK Expression as a Cell Surface Marker of Human Osteoclast Precursors in Peripheral Blood, Bone Marrow, and Giant Cell Tumors of Bone

A. Evdokiou, A. Zannettino, Gerald J Atkins, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

SaOS2 Osteosarcoma Cells as an In Vitro Model for Studying the Transition of Human Osteoblasts to Osteocytes

A. Evdokiou, M. Prideaux, D. Findlay, 2014, Calcified Tissue International.

Zoledronate Enhances the Cytotoxicity of Gamma Delta T Cell Immunotherapy in an Orthotopic Mouse Model of Osteolytic Osteosarcoma

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2018 .

Investigation of Spontaneously Aborted Concepti for Microbial DNA: Investigation for Cytomegalovirus DNA Using Polymerase Chain Reaction

A. Evdokiou, R. A. Putland, Judith Ford, 1990, The Australian & New Zealand journal of obstetrics & gynaecology.

Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro

A. Evdokiou, T. Price, J. Hardingham, 2016, Journal of Experimental & Clinical Cancer Research.

RANKL Expression Is Related to the Differentiation State of Human Osteoblasts

A. Evdokiou, S. Gronthos, A. Zannettino, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Death to the bad guys: Targeting cancer via Apo2L/TRAIL

A. Evdokiou, D. Findlay, S. Bouralexis, 2005, Apoptosis.

ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer

M. Loda, I. Mills, A. Scott, 2021, Cancer Research.

The role of osteoclasts and tumour-associated macrophages in osteosarcoma metastasis.

A. Evdokiou, N. Saunders, L. Endo-Munoz, 2012, Biochimica et biophysica acta.

CCL2-driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model

J. Pollard, A. Evdokiou, Xuan Sun, 2017, Breast Cancer Research.

Hormonal regulation of the cytokine microenvironment in the mammary gland.

A. Evdokiou, S. Robertson, W. Ingman, 2014, Journal of reproductive immunology.

Macrophage Phenotype in the Mammary Gland Fluctuates over the Course of the Estrous Cycle and Is Regulated by Ovarian Steroid Hormones1

A. Evdokiou, S. Robertson, W. Ingman, 2013, Biology of reproduction.

Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling.

David M. Thomas, J. Desai, G. Farshid, 2014, Cancer research.

Nutlin-3a Is a Potential Therapeutic for Ewing Sarcoma

M. Brown, K. Pishas, P. Neilsen, 2010, Clinical Cancer Research.

Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells

L. To, A. Evdokiou, S. Gronthos, 2014, Haematologica.

Apo2L/TRAIL Inhibits Tumor Growth and Bone Destruction in a Murine Model of Multiple Myeloma

V. Ponomarev, A. Evdokiou, A. Zannettino, 2009, Clinical Cancer Research.

Biological Mechanisms and Therapeutic Opportunities in Mammographic Density and Breast Cancer Risk

A. Evdokiou, W. Ingman, P. Dasari, 2021, Cancers.

Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.

V. Ponomarev, A. Evdokiou, D. Leach, 2017, International journal of oncology.

The combined use of Camellia sinensis and metronomic zoledronic acid in a breast cancer-induced osteolysis mouse model

A. Evdokiou, K. Fung, G. Yue, 2015, Journal of Cancer Research and Clinical Oncology.

Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models

M. Brown, Nicole L. Wittwer, A. Evdokiou, 2020, Molecular Imaging and Biology.

Multifunctional microspherical magnetic and pH responsive carriers for combination anticancer therapy engineered by droplet-based microfluidics.

A. Evdokiou, D. Losic, Abel Santos, 2017, Journal of materials chemistry. B.

Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

A. Evdokiou, H. Du, Xuan Sun, 2021, Breast cancer research : BCR.

The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro.

L. To, A. Evdokiou, S. Gronthos, 2004, Bone.

Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells.

A. Evdokiou, A. Skaltsounis, A. Constantinou, 2012, Biochemical and biophysical research communications.

Foxp3 heterozygosity does not overtly affect mammary gland development during puberty or the oestrous cycle in mice.

S. Barry, A. Evdokiou, W. Ingman, 2020, Reproduction, fertility, and development.

Structurally engineered anodic alumina nanotubes as nano-carriers for delivery of anticancer therapeutics.

Gagandeep Kaur, Dusan Losic, Abel Santos, 2014, Biomaterials.

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

K. Mrozik, K. Vandyke, A. Evdokiou, 2019, Neoplasia.

Engineering of Micro- to Nanostructured 3D-Printed Drug-Releasing Titanium Implants for Enhanced Osseointegration and Localized Delivery of Anticancer Drugs.

Gagandeep Kaur, Dusan Losic, Luis Lima-Marques, 2017, ACS applied materials & interfaces.

Identification of a novel calcitonin-response element in the promoter of the human p21WAF1/CIP1 gene.

T. Sakai, A. Evdokiou, D. Findlay, 2000, Journal of molecular endocrinology.

Identiﬁcation of a novel calcitonin-response element in the promoter of the human p21 WAF1/CIP1 gene

A. Evdokiou, L. Raggatt, D. Findlay, 2000 .

Combination of Near-Infrared Photoimmunotherapy Using Trastuzumab and Small Protein Mimetic for HER2-Positive Breast Cancer

A. Evdokiou, H. Yamaguchi, T. Morita, 2021, International journal of molecular sciences.

Near-Infrared Photoimmunotherapy Using a Small Protein Mimetic for HER2-Overexpressing Breast Cancer

A. Evdokiou, H. Yamaguchi, N. Pantarat, 2019, International journal of molecular sciences.

Recombinant sclerostin antagonizes effects of ex vivo mechanical loading in trabecular bone and increases osteocyte lacunar size.

A. Evdokiou, D. Findlay, K. Khalid, 2018, American journal of physiology. Cell physiology.

From The Mine to Cancer Therapy: Natural and Biodegradable Theranostic Silicon Nanocarriers from Diatoms for Sustained Delivery of Chemotherapeutics

A. Evdokiou, D. Losic, G. Fetih, 2016, Advanced healthcare materials.

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

G. Screaton, A. Evdokiou, Malcolm D. Smith, 2009, Arthritis research & therapy.

Naturally Derived Iron Oxide Nanowires from Bacteria for Magnetically Triggered Drug Release and Cancer Hyperthermia in 2D and 3D Culture Environments: Bacteria Biofilm to Potent Cancer Therapeutic.

A. Evdokiou, D. Losic, Ye Wang, 2016, Biomacromolecules.

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2014, International journal of oncology.

CCL2-Mediated Stromal Interactions Drive Macrophage Polarization to Increase Breast Tumorigenesis

A. Evdokiou, L. Woolford, W. Ingman, 2023, International journal of molecular sciences.

A role for the phosphatidylinositol 3-kinase--protein kinase C zeta--Sp1 pathway in the 1,25-dihydroxyvitamin D3 induction of the 25-hydroxyvitamin D3 24-hydroxylase gene in human kidney cells.

A. Evdokiou, A. Ferrante, H. Morris, 2010, Cellular signalling.

Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis?

A. Evdokiou, A. Zannettino, N. Sims, 2008, Blood.

Titanium wire implants with nanotube arrays: A study model for localized cancer treatment.

A. Evdokiou, K. Gulati, D. Losic, 2016, Biomaterials.

Anticancer efficacy of the hypoxia‐activated prodrug evofosfamide (TH‐302) in osteolytic breast cancer murine models

V. Ponomarev, A. Evdokiou, V. Panagopoulos, 2016, Cancer medicine.

Calcitonin decreases the adherence and survival of HEK-293 cells by a caspase-independent mechanism.

A. Evdokiou, D. Findlay, L. Raggatt, 2002, The Journal of endocrinology.

A case of autosomal dominant osteopetrosis type II with a severe bone phenotype but no amino acid converting mutation in the CLCN7 gene

N. Ito, A. Evdokiou, P. Roschger, 2021, medRxiv.

In vivo toxicological assessment of electrochemically engineered anodic alumina nanotubes: a study of biodistribution, subcutaneous implantation and intravenous injection.

A. Evdokiou, V. Panagopoulos, D. Losic, 2017, Journal of materials chemistry. B.

Chromosomal localization of the human urothelial "tetraspan" gene, UPK1B, to 3q13.3-q21 and detection of a TaqI polymorphism.

A. Evdokiou, J. Finch, G. Webb, 1997, Genomics.

The human growth-arrest-specific gene GAS1 maps outside the candidate region of the gene for nevoid basal cell carcinoma syndrome.

G. Chenevix-Trench, A. Evdokiou, B. Wainwright, 1995, Cytogenetics and Cell Genetics.