H. Kurihara

发表

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

Yumiko K Kawamura, Y. Uchijima, N. Horike, 2010, The Journal of clinical investigation.

Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity.

H. Kurihara, M. Murakami, K. Kataoka, 2004, European journal of biochemistry.

Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.

Y. Uchijima, N. Horike, T. Asano, 2008, American journal of physiology. Endocrinology and metabolism.

Par14 Protein Associates with Insulin Receptor Substrate 1 (IRS-1), Thereby Enhancing Insulin-induced IRS-1 Phosphorylation and Metabolic Actions

T. Uchida, T. Asano, H. Kurihara, 2013, The Journal of Biological Chemistry.

Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.

D. Harats, A. Ziober, Y. Kurihara, 1995, The Journal of clinical investigation.

Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.

D. Harats, A. Ziober, Y. Kurihara, 1995 .

A Soluble Form of LMIR5/CD300b Amplifies Lipopolysaccharide-Induced Lethal Inflammation in Sepsis

H. Kurihara, T. Kitamura, Y. Yamanishi, 2012, The Journal of Immunology.

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Sadao Kimura, Masashi Yanagisawa, Hiroki Kurihara, 1988, Nature.

Calpain 6 Is Involved in Microtubule Stabilization and Cytoskeletal Organization

H. Aburatani, Y. Uchijima, Kazuo Tonami, 2007, Molecular and Cellular Biology.

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.

Janet Rossant, Hiroshi Nojima, Hiroshi Kiyonari, 2009, Developmental cell.

Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.

H. Aburatani, H. Kurihara, A. Mitani, 2009, American journal of respiratory and critical care medicine.

Spatio‐temporal dynamics of gene expression of the Edn1‐Dlx5/6 pathway during development of the lower jaw

G. Merlo, H. Kurihara, G. Levi, 2010, Genesis.

Beta-defensin overexpression induces progressive muscle degeneration in mice.

Y. Ouchi, T. Amano, T. Asano, 2007, American journal of physiology. Cell physiology.

Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells.

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1990, Biochemical and biophysical research communications.

Ephrin-B2 Induces Migration of Endothelial Cells Through the Phosphatidylinositol-3 Kinase Pathway and Promotes Angiogenesis in Adult Vasculature

T. Suda, H. Kurihara, Y. Oike, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Regulation of Mitochondrial Function by Deacetylase in Early Embryos

Yumiko K Kawamura, H. Kurihara, Yumiko K. Kawamura, 2012 .

Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells

Y. Yazaki, I. Komuro, H. Kurihara, 1988, FEBS letters.

Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature.

R. Nagai, Y. Yazaki, Y. Kurihara, 2000, Circulation.

Vascular Abnormalities and Elevated Blood Pressure in Mice Lacking Adrenomedullin Gene

H. Nishimatsu, R. Nagai, Y. Yazaki, 2001, Circulation.

Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation.

Y. Kurihara, H. Kurihara, A. Turnley, 1996, Development.

Differing contributions of the first and second pharyngeal arches to tympanic membrane formation in the mouse and chick

S. Iseki, H. Kurihara, F. Rijli, 2017, Development.

Resistin-Like Molecule &bgr; Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development

H. Aburatani, Koichi Nishiyama, T. Asano, 2013, Arteriosclerosis, thrombosis, and vascular biology.

LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8.

K. Inoki, T. Asano, H. Kurihara, 2012, Obesity research & clinical practice.

Differential cooperation between dHAND and three different E-proteins.

H. Kurihara, M. Murakami, K. Kataoka, 2004, Biochemical and biophysical research communications.

Endothelin-1 regulates the dorsoventral branchial arch patterning in mice

Kazuo Tonami, Y. Kurihara, H. Kurihara, 2004, Mechanisms of Development.

Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1

Y. Uchijima, Kazuo Tonami, Koichi Nishiyama, 2011, Journal of Cell Science.

Lessons from gene deletion of endothelin systems

Y. Yazaki, Y. Kurihara, H. Kurihara, 2001 .

Evidence for association between paraoxonase gene polymorphisms and atherosclerotic diseases.

Y. Yazaki, N. Kato, Y. Kurihara, 2000, Atherosclerosis.

Fluvastatin ameliorates the hyperhomocysteinemia-induced endothelial dysfunction: the antioxidative properties of fluvastatin.

H. Kurihara, M. Kurabayashi, R. Nagai, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Protein Kinase A-regulated Nucleocytoplasmic Shuttling of Id1 during Angiogenesis*

Y. Uchijima, Koichi Nishiyama, T. Asano, 2007, Journal of Biological Chemistry.

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Satoshi O. Suzuki, K. Shin‐ya, K. Nakao, 2015, Proceedings of the National Academy of Sciences.

Id1 Gene Transfer Confers Angiogenic Property on Fully Differentiated Endothelial Cells and Contributes to Therapeutic Angiogenesis

Koichi Nishiyama, Y. Kurihara, H. Kurihara, 2005, Circulation.

ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.

H. Nishimatsu, R. Nagai, Y. Yazaki, 2000, The Journal of clinical investigation.

Glucose transporter and Na+/glucose cotransporter as molecular targets of anti-diabetic drugs.

Y. Uchijima, T. Asano, H. Kurihara, 2004, Current medicinal chemistry.

Elevated Sympathetic Nervous Activity in Mice Deficient in &agr;CGRP

H. Nishimatsu, Y. Suematsu, Y. Yazaki, 2001, Circulation research.

Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.

T. Asano, H. Kurihara, Hiraku Ono, 2010, Diabetes research and clinical practice.

The Possible Role of Endothelin‐1 in the Pathogenesis of Coronary Vasospasm

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1989, Journal of cardiovascular pharmacology.

Lack of sex-specific effects on the association between angiotensin-converting enzyme gene polymorphism and hypertension in Japanese.

Y. Yazaki, N. Kato, H. Kurihara, 1999, Hypertension research : official journal of the Japanese Society of Hypertension.

Angiotensinogen gene and essential hypertension in the Japanese: extensive association study and meta-analysis on six reported studies.

Y. Yazaki, N. Kato, H. Kurihara, 1999, Journal of hypertension.

Evaluation of the atrial natriuretic peptide gene in stroke.

Y. Yazaki, Shotai Kobayashi, N. Kato, 2002, Atherosclerosis.

Resistance to Neointimal Hyperplasia and Fatty Streak Formation in Mice With Adrenomedullin Overexpression

Y. Yazaki, Toru Suzuki, Y. Kurihara, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase.

K. Hirata, Y. Yazaki, H. Kurihara, 1998, The Journal of clinical investigation.

Serum concentrations of resistin-like molecules β and γ are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow

Y. Uchijima, N. Horike, T. Asano, 2005, Diabetologia.

Inhibitory Effect of Natriuretic Peptides on Aldosterone Synthase Gene Expression in Cultured Neonatal Rat Cardiocytes

K. Nakao, H. Kurihara, H. Ogawa, 2003, Circulation.

Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.

Y. Kurihara, H. Kurihara, K. Saigenji, 2008, Gastroenterology.

Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice.

H. Kurihara, N. Nakagata, N. Harada, 2011, The Journal of nutritional biochemistry.

4F2hc stabilizes GLUT1 protein and increases glucose transport activity.

T. Asano, H. Kurihara, H. Katagiri, 2011, American journal of physiology. Cell physiology.

Transcriptional activity of Pax3 is co-activated by TAZ.

Y. Uchijima, T. Asano, Y. Kurihara, 2006, Biochemical and biophysical research communications.

Title: Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity Authors

Oka, T. Uchida, N. Horike, 2010 .

Pin1 Associates with and Induces Translocation of CRTC2 to the Cytosol, Thereby Suppressing cAMP-responsive Element Transcriptional Activity*

T. Uchida, N. Horike, T. Asano, 2010, The Journal of Biological Chemistry.

Association Analysis of &bgr;2-Adrenergic Receptor Polymorphisms With Hypertension in Japanese

Y. Yazaki, N. Kato, H. Kurihara, 2001, Hypertension.

G protein beta3 subunit variant and essential hypertension in Japanese.

Y. Yazaki, N. Kato, H. Kurihara, 1998, Hypertension.

Protein b 3 Subunit Variant and Essential Hypertension in Japanese

Y. Yazaki, N. Kato, H. Kurihara, 1998 .

Antithrombin prevents reperfusion-induced hepatic apoptosis by enhancing insulin-like growth factor-I production in mice

H. Kurihara, N. Nakagata, N. Harada, 2008, Critical care medicine.

A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia.

M. Makuuchi, H. Kurihara, M. Omata, 2000, Journal of molecular and cellular cardiology.

Ex vivo gene delivery of ephrin-B2 induces development of functional collateral vessels in a rabbit model of hind limb ischemia.

H. Kurihara, H. Koyama, M. Katsu, 2009, Journal of vascular surgery.

Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice.

Y. Kurihara, H. Kurihara, Masahiko Watanabe, 2011, American journal of physiology. Heart and circulatory physiology.

[Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor].

Y. Yazaki, Y. Kurihara, H. Kurihara, 1997, Journal of cardiology.

Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.

Y. Uchijima, T. Asano, H. Kurihara, 2006, Diabetes research and clinical practice.

SIRT3 positively regulates the expression of folliculogenesis- and luteinization-related genes and progesterone secretion by manipulating oxidative stress in human luteinized granulosa cells.

K. Oda, Yumiko K Kawamura, H. Kurihara, 2014, Endocrinology.

Administration of capsaicin and isoflavone promotes hair growth by increasing insulin-like growth factor-I production in mice and in humans with alopecia.

H. Kurihara, N. Nakagata, M. Arai, 2007, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Renal damage and salt-dependent hypertension in aged transgenic mice overexpressing endothelin-1

H. Nishimatsu, O. Ueda, R. Nagai, 2002, Journal of Molecular Medicine.

Transforming growth factor-β stimulates the expression of endothelin mRNA by vascular endothelial cells

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1989 .

Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.

Koichi Nishiyama, H. Kurihara, T. Takezawa, 2010, Blood.

Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.

N. Matsuki, M. Yanagisawa, H. Kurihara, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Endothelial responses of the aorta from adrenomedullin transgenic mice and knockout mice.

H. Nishimatsu, R. Takeda, H. Kurihara, 2003, Hypertension research : official journal of the Japanese Society of Hypertension.

Endothelin-1 regulates normal cardiovascular development and cardiac cellular hypertrophy.

Y. Yazaki, I. Komuro, T. Yamazaki, 1996, Journal of cardiac failure.

An Application of Melting Curve Analysis to Large-Scale Genetic Analysis in Atherosclerotic Disease: Two Linked Polymorphisms of Glycoprotein la Gene and Myocardial Infarction in Japanese

Y. Yazaki, H. Kurihara, R. Nagai, 2001 .

Endothelin: a potent vasoconstrictor associated with coronary vasospasm.

R. Nagai, Y. Yazaki, H. Kurihara, 1989, Life sciences.

Gene Expression of Bone Matrix Proteins and Endothelin Receptors in Endothelin‐1–Deficient Mice Revealed by In Situ Hybridization

Y. Yazaki, Y. Kurihara, H. Kurihara, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Role of Endogenous Adrenomedullin in the Regulation of Vascular Tone and Ischemic Renal Injury: Studies on Transgenic/Knockout Mice of Adrenomedullin Gene

H. Nishimatsu, H. Kurihara, R. Nagai, 2002, Circulation research.

Unique roles of G protein-coupled histamine H2 and gastrin receptors in growth and differentiation of gastric mucosa.

T. Matsui, T. Asano, H. Kurihara, 2004, European journal of pharmacology.

Structural and functional characterization of gastric mucosa and central nervous system in histamine H2 receptor-null mice.

T. Asano, Y. Kurihara, H. Kurihara, 2003, European journal of pharmacology.

Lack of Association between the Platelet Glycoprotein Ia C807T Gene Polymorphism and Myocardial Infarction in Japanese

R. Nagai, H. Kurihara, R. Nagai, 2001, Thrombosis and Haemostasis.

Stimulation of FcγRI on Primary Sensory Neurons Increases Insulin-Like Growth Factor-I Production, Thereby Reducing Reperfusion-Induced Renal Injury in Mice

H. Kurihara, N. Nakagata, N. Harada, 2010, The Journal of Immunology.

Effects of Topical Application of α-D-Glucosylglycerol on Dermal Levels of Insulin-Like Growth Factor-I in Mice and on Facial Skin Elasticity in Humans

H. Kurihara, N. Nakagata, N. Harada, 2010, Bioscience, biotechnology, and biochemistry.

Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans.

H. Kurihara, N. Nakagata, N. Harada, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Calcitonin gene‐related peptide mediates acid‐induced lung injury in mice

Y. Ouchi, Y. Kurihara, H. Kurihara, 2007, Respirology.

RETRACTED: Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I, thereby reducing reperfusion-induced apoptosis in mice

H. Kurihara, N. Nakagata, N. Harada, 2007, Neuropharmacology.

Contribution of sensory neurons to sex difference in the development of stress-induced gastric mucosal injury in mice.

H. Kurihara, S. Shimada, N. Nakagata, 2006, Gastroenterology.

Targeted disruption of adrenomedullin and alphaCGRP genes reveals their distinct biological roles.

H. Kurihara, T. Shindo, T. Kuwaki, 2003, Hypertension research : official journal of the Japanese Society of Hypertension.

Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice.

Y. Ouchi, Y. Kurihara, H. Kurihara, 2002, American journal of physiology. Lung cellular and molecular physiology.

Cerebral microvessel endothelium is producing endothelin

K. Takakura, Y. Yazaki, S. Murota, 1990, Brain Research.

Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression.

H. Okano, K. Kimura, A. Fukamizu, 2004, The Journal of clinical investigation.

Responses of blood pressure and catecholamine metabolism to high salt loading in endothelin-1 knockout mice.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1999, Hypertension research : official journal of the Japanese Society of Hypertension.

Endothelin-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis.

Y. Yazaki, T. Ishikawa, H. Kurihara, 1997, Circulation.

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

Yukiko Kurihara, Akiyo Matsumoto, Hiroyuki Aburatani, 1997, Nature.

Production of endothelin-1 in vascular endothelial cells is regulated by factors associated with vascular injury.

Y. Yazaki, H. Kurihara, K. Maemura, 1992, Gerontology.

micevia functional mechanism in knockout Disruption of ET-1 gene enhances pulmonary responses

Y. Ouchi, Y. Kurihara, H. Kurihara, 2015 .

Disruption of ET-1 gene enhances pulmonary responses to methacholine via functional mechanism in knockout mice.

Y. Ouchi, R. Nagai, Y. Kurihara, 1999, Journal of applied physiology.

The “ Cardiac Neural Crest ” Concept Revisited 30

H. Kurihara, Y. Arima, S. Miyagawa‐Tomita, 2016 .

Postotic and preotic cranial neural crest cells differently contribute to thyroid development.

Y. Kurihara, H. Kurihara, T. Nakanishi, 2016, Developmental biology.

The “Cardiac Neural Crest” Concept Revisited

H. Kurihara, Y. Arima, S. Miyagawa‐Tomita, 2016 .

Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms

Y. Uchijima, Koichi Nishiyama, Y. Kurihara, 2013, Mechanisms of Development.

Impaired Development of the Thyroid and Thymus in Endothelin‐1 Knockout Mice

Y. Yazaki, Y. Kurihara, H. Kurihara, 1995, Journal of cardiovascular pharmacology.

In Vitro and In Vivo Anticancer Activity of Human β-Defensin-3 and Its Mouse Homolog.

Y. Ouchi, H. Kurihara, T. Nagase, 2016, Anticancer research.

Airway hyperresponsiveness to methacholine in mutant mice deficient in endothelin-1.

Y. Ouchi, Y. Yazaki, Y. Kurihara, 1998, American journal of respiratory and critical care medicine.

A Novel Mouse β-Defensin, mBD-6, Predominantly Expressed in Skeletal Muscle*

Y. Ouchi, H. Kurihara, S. Fukuhara, 2001, The Journal of Biological Chemistry.

A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 null mutant mice develop renal lesions mimicking obstructive nephropathy.

K. Matsushima, H. Kurihara, T. Shindo, 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Adrenomedullin insufficiency increases allergen-induced airway hyperresponsiveness in mice.

Y. Ouchi, H. Kurihara, T. Shindo, 2007, Journal of applied physiology.

A Polymorphic Variant C1367R of the Werner Helicase Gene and Atherosclerotic Diseases in the Japanese Population

Y. Yazaki, H. Kurihara, T. Sugiyama, 1999, Thrombosis and Haemostasis.

ADAMTS-1 is involved in normal follicular development, ovulatory process and organization of the medullary vascular network in the ovary.

K. Matsushima, H. Kurihara, K. Kuno, 2005, Journal of molecular endocrinology.

Autonomy and Non-autonomy of Angiogenic Cell Movements Revealed by Experiment-Driven Mathematical Modeling.

Akiyoshi Uemura, T. Suda, R. Kobayashi, 2015, Cell reports.

Central effect of endothelin on blood pressure in conscious rats.

Y. Ouchi, Y. Yazaki, H. Kurihara, 1989, The American journal of physiology.

Renal Injury : Studies on Transgenic / Knockout Mice of Adrenomedullin Gene Role of Endogenous Adrenomedullin in the Regulation of Vascular Tone and Ischemic

H. Nishimatsu, H. Kurihara, R. Nagai, 2002 .

A Novel Protein Kinase B (PKB)/AKT-binding Protein Enhances PKB Kinase Activity and Regulates DNA Synthesis*

Y. Uchijima, N. Horike, T. Asano, 2005, Journal of Biological Chemistry.

Overexpression of 15-Lipoxygenase in Vascular Endothelium Accelerates Early Atherosclerosis in LDL Receptor–Deficient Mice

J. George, D. Harats, H. Kurihara, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Transforming growth factor-beta stimulates the expression of endothelin mRNA by vascular endothelial cells.

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1989, Biochemical and biophysical research communications.

Identification and developmental analysis of endothelin receptor type-A expressing cells in the mouse kidney.

Y. Uchijima, Koichi Nishiyama, Y. Kurihara, 2011, Gene expression patterns : GEP.

Human polymorphonuclear leukocytes have dual effects on endothelin-1: The induction of endothelin-1 mRNA expression in vascular endothelial cells and modification of the endothelin-1 molecule

Y. Yazaki, H. Kurihara, R. Nagai, 1993, Heart and Vessels.

Human polymorphonuclear leukocytes have dual effects on endothelin-1: The induction of endothelin-1 mRNA expression in vascular endothelial cells and modification of the endothelin-1 molecule

Y. Yazaki, H. Kurihara, R. Nagai, 2005, Heart and Vessels.

ENDOTHELIN IN THE CENTRAL CONTROL OF CARDIOVASCULAR AND RESPIRATORY FUNCTIONS

Y. Yazaki, M. Yanagisawa, Y. Kurihara, 1999, Clinical and experimental pharmacology & physiology.

Systemic and renal response to salt loading in endothelin-1 knockout mice.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1998, Journal of cardiovascular pharmacology.

The Role of Endothelin‐1 in Cardiovascular Development a

Y. Yazaki, Y. Kurihara, H. Kurihara, 1997, Annals of the New York Academy of Sciences.

Evolving maps in craniofacial development.

Y. Kurihara, H. Kurihara, G. Levi, 2010, Seminars in cell & developmental biology.

Molecular Dynamics of Retinoic Acid-Induced Craniofacial Malformations: Implications for the Origin of Gnathostome Jaws

M. Ekker, P. Janvier, G. Merlo, 2007, PloS one.

Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells.

N. Horike, T. Asano, H. Kurihara, 2008, Placenta.

Inflammation in Sepsis Lipopolysaccharide-Induced Lethal A Soluble Form of LMIR5/CD300b Amplifies

H. Kurihara, T. Kitamura, S. Ito, 2012 .

Sequence analysis, chromosomal location, and developmental expression of the mouse preproendothelin-1 gene.

N. Copeland, D. Gilbert, N. Jenkins, 1996, Genomics.

RT-PCR for CYP 11 B 2 and GAPDH : Design of Primers and Probes

K. Nakao, H. Kurihara, H. Ogawa, 2003 .

Evidence for the Physiological and Pathological Roles of Adrenomedullin from Genetic Engineering in Mice

Y. Kurihara, H. Kurihara, R. Nagai, 2001, Annals of the New York Academy of Sciences.

A case of Takayasu's disease with ruptured carotid aneurysm.

M. Isobe, H. Kurihara, M. Kurabayashi, 1986, Japanese heart journal.

Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery

Akiyoshi Uemura, Yutaka Yoshida, Y. Uchijima, 2021, iScience.

Resistin-like Molecule β Activates MAPKs, Suppresses Insulin Signaling in Hepatocytes, and Induces Diabetes, Hyperlipidemia, and Fatty Liver in Transgenic Mice on a High Fat Diet*

Y. Uchijima, N. Horike, Koichi Nishiyama, 2005, Journal of Biological Chemistry.

Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.

Y. Uchijima, N. Horike, T. Asano, 2005, American journal of physiology. Endocrinology and metabolism.

Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.

Tetsurou Yamamoto, R. Harvey, H. Kurihara, 2007, Molecular genetics and metabolism.

Developmental mechanisms of the tympanic membrane in mammals and non‐mammalian amniotes

S. Iseki, H. Kurihara, S. Kuratani, 2016, Congenital anomalies.

Endothelium-Derived Novel Vasoconstrictor Peptide Endothelin: A Possible Endogenous Agonist for Voltage-Dependent Ca2+ Channels

M. Yanagisawa, H. Kurihara, T. Masaki, 1988 .

Administration of Oral Contraceptives Could Alleviate Age-Related Fertility Decline Possibly by Preventing Ovarian Damage in a Mouse Model

Yumiko K Kawamura, H. Kurihara, Y. Osuga, 2018, Reproductive Sciences.

602 Abnormal central respiratory mechanism in endothelin-1 deficient mice: a study in medulla-spinal cord preparation

Y. Kurihara, H. Kurihara, T. Kuwaki, 1996, Neuroscience Research.

Impaired ventilatory responses to hypoxia and hypercapnia in mutant mice deficient in endothelin-1.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1996, The American journal of physiology.

Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1

Y. Ouchi, T. Kodama, K. Jishage, 1994, Nature.

Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane.

H. Kurihara, K. Hamase, K. Sekimizu, 2015, Nature chemical biology.

Polymorphism of the methionine synthase gene : association with homocysteine metabolism and late-onset vascular diseases in the Japanese population.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

H. Aburatani, M. Nangaku, H. Kurihara, 2020, Communications biology.

Lysine demethylase 7a regulates the anterior-posterior development in mouse by modulating the transcription of Hox gene cluster

H. Aburatani, M. Nangaku, H. Kurihara, 2019, bioRxiv.

Craniofacial traits determined by neural crest cells-restricted expression of Dlx5/6: probing the origin of matching functional jaws

Y. Kurihara, H. Kurihara, G. Levi, 2018 .

Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process.

H. Aburatani, T. Kodama, Y. Uchijima, 2015, Developmental biology.

Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids

Y. Kurihara, H. Kurihara, J. Hitomi, 2015, Nature Communications.

An endothelin-1 switch specifies maxillomandibular identity

M. Ekker, Y. Uchijima, Kazuo Tonami, 2008, Proceedings of the National Academy of Sciences.

Recombinase-mediated cassette exchange reveals the selective use of Gq/G11-dependent and -independent endothelin 1/endothelin type A receptor signaling in pharyngeal arch development

Y. Uchijima, T. Amano, Y. Kurihara, 2008, Development.

Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation

Y. Uchijima, Kazuo Tonami, Koichi Nishiyama, 2010, Development.

Genetic analysis of the atrial natriuretic peptide gene in essential hypertension.

Y. Yazaki, N. Kato, H. Kurihara, 2000, Clinical science.

Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.

Kazuo Tonami, H. Kurihara, H. Sorimachi, 2016, The Journal of clinical investigation.

Preotic neural crest cells contribute to coronary artery smooth muscle involving endothelin signalling

Y. Uchijima, Koichi Nishiyama, Y. Kurihara, 2012, Nature Communications.

Germ-line contribution of embryonic stem cells in chimeric mice: influence of karyotype and in vitro differentiation ability.

T. Kodama, K. Jishage, O. Ueda, 1997, Experimental animals.

Production of a Germ-line Chimera by Coculture of Zona-free Embryos with Frozen-thawed Embryonic Stem Cells

T. Kodama, K. Jishage, O. Ueda, 1994 .

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.

H. Aburatani, Takahiro Sato, P. Igarashi, 2008, American journal of physiology. Renal physiology.

Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy (*)

R Aikawa, S. Kudoh, Y. Hiroi, 1996, The Journal of Biological Chemistry.

The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.

Elizabeth A. McClellan, M. Mayr, Y. Pinto, 2013, Cell metabolism.

Maintenance of genomic methylation patterns during preimplantation development requires the somatic form of DNA methyltransferase 1.

Y. Uchijima, T. Asano, Y. Kurihara, 2008, Developmental biology.

Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model*

T. Uchida, T. Inaba, T. Asano, 2012, The Journal of Biological Chemistry.

Dnm3os, a non‐coding RNA, is required for normal growth and skeletal development in mice

Takahiro Sato, T. Amano, H. Kurihara, 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

Renal sympathetic nerve activity in mice: comparison between mice and rats and between normal and endothelin-1 deficient mice

Yukiko Kurihara, Hiroki Kurihara, Y. Yazaki, 1998, Brain Research.

Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide

Y. Kurihara, H. Kurihara, Tatsunori Suzuki, 2008, Proceedings of the National Academy of Sciences.

An in vitro coculture model of transmigrant monocytes and foam cell formation.

Y. Yazaki, E. Niki, H. Kurihara, 2000, Arteriosclerosis, thrombosis, and vascular biology.

An In Vitro Coculture Model of Transmigrant Monocytes and Foam Cell Formation

T. Kodama, Y. Yazaki, E. Niki, 1999 .

Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1997, Circulation.

Antithrombin reduces reperfusion-induced liver injury in mice by enhancing sensory neuron activation

H. Kurihara, N. Nakagata, M. Uchiba, 2006, Thrombosis and Haemostasis.

Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells.

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1989, Biochemical and biophysical research communications.

A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

Atsushi Yoshiki, Kuniya Abe, Shigeharu Wakana, 2009, PloS one.

Left cervical aortic arch with aortic coarctation and saccular aneurysm.

I. Komuro, T. Yamazaki, H. Kurihara, 2000, Japanese circulation journal.

AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver*

Y. Uchijima, N. Horike, Koichi Nishiyama, 2008, Journal of Biological Chemistry.

RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells

Akiyoshi Uemura, S. Nishikawa, K. Nishida, 2020, The EMBO journal.

Lack of association between the alpha-adducin locus and essential hypertension in the Japanese population.

Y. Yazaki, N. Kato, H. Kurihara, 1998, Hypertension.

Lack of Association Between the α-Adducin Locus and Essential Hypertension in the Japanese Population

Y. Yazaki, N. Kato, H. Kurihara, 1998 .

Dlx5-augmentation in neural crest cells reveals early development and differentiation potential of mouse apical head mesenchyme

S. Iseki, H. Kurihara, Miki Shimizu, 2021, Scientific Reports.

Resveratrol improves cognitive function in mice by increasing production of insulin-like growth factor-I in the hippocampus.

H. Kurihara, N. Nakagata, N. Harada, 2011, The Journal of nutritional biochemistry.

Mouse Hoxa2 mutations provide a model for microtia and auricle duplication

H. Kurihara, N. Bobola, Shilu Amin, 2013, Development.

Disruption of cytoskeletal structures mediates shear stress-induced endothelin-1 gene expression in cultured porcine aortic endothelial cells.

Y. Yazaki, H. Kurihara, K. Maemura, 1993, The Journal of clinical investigation.

Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow.

Y. Uchijima, N. Horike, T. Asano, 2005, Diabetologia.

Shear stress increases heparin-binding epidermal growth factor-like growth factor mRNA levels in human vascular endothelial cells.

R. Nagai, Y. Yazaki, H. Kurihara, 1993, Biochemical and biophysical research communications.

Comprehensive analysis of the renin–angiotensin gene polymorphisms with relation to hypertension in the Japanese

Y. Yazaki, N. Kato, H. Kurihara, 2000, Journal of hypertension.

A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.

D. Srivastava, Y. Yazaki, E. Olson, 1998, Development.

Overexpression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Induces Intramyocardial Vasculopathy in Apolipoprotein E–Null Mice

T. Kita, H. Kurihara, T. Sawamura, 2005, Circulation research.

Homocysteine as a Risk Factor for Restenosis after Coronary Angioplasty

Y. Yazaki, H. Kurihara, R. Nagai, 2000, Thrombosis and Haemostasis.

ACE and MTHFR Gene Polymorphisms: Genetic Coronary Risk Factors Relating to Different Aspects of Pathophysiology

Y. Yazaki, H. Kurihara, J. Taguchi, 1998, Thrombosis and Haemostasis.

PHYSIOLOGICAL ROLE OF BRAIN ENDOTHELIN IN THE CENTRAL AUTONOMIC CONTROL: FROM NEURON TO KNOCKOUT MOUSE

Y. Yazaki, Y. Kurihara, H. Kurihara, 1997, Progress in Neurobiology.

Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.

I. Komuro, T. Asano, H. Kurihara, 2012, American journal of physiology. Endocrinology and metabolism.

Peptidyl-prolyl Cis/Trans Isomerase NIMA-interacting 1 Associates with Insulin Receptor Substrate-1 and Enhances Insulin Actions and Adipogenesis

T. Uchida, N. Horike, T. Asano, 2011, The Journal of Biological Chemistry.

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract

G. Sobue, H. Kurihara, M. Katsuno, 2012, Nature Medicine.

Evaluation of the poly(ADP-ribose) polymerase gene in human stroke.

Y. Yazaki, N. Kato, H. Kurihara, 2000, Atherosclerosis.

Endothelin and neural crest development.

R. Nagai, Y. Yazaki, Y. Kurihara, 1999, Cellular and molecular biology.

Nuclear transfer reprogramming does not improve the low developmental potency of embryonic stem cells induced by long-term culture.

T. Amano, H. Kurihara, M. Gertsenstein, 2006, Reproduction.

SGLT as a therapeutic target

Y. Uchijima, T. Asano, H. Kurihara, 2004 .

Temporal requirement of signaling cascade involving endothelin-1/endothelin receptor type A in branchial arch development

Yukiko Kurihara, Yuichiro Arima, Hiroki Kurihara, 2004, Mechanisms of Development.

Role of Ca2+ and protein kinase C in shear stress-induced actin depolymerization and endothelin 1 gene expression.

R. Nagai, Y. Yazaki, H. Kurihara, 1994, Circulation research.

Diet-Induced Hyperhomocysteinemia Exacerbates Neointima Formation in Rat Carotid Arteries After Balloon Injury

Y. Yazaki, Y. Kurihara, H. Kurihara, 2001, Circulation.

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.

R. Nagai, Y. Yazaki, T. Ishikawa, 1995, The Journal of clinical investigation.

Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart

I. Komuro, K. Otsu, N. Mochizuki, 2014, Nature Communications.

Lack of evidence for association between the endothelial nitric oxide synthase gene and hypertension.

Y. Yazaki, N. Kato, H. Kurihara, 1999, Hypertension.

Roles of calcitonin gene-related peptide in facilitation of wound healing and angiogenesis.

Y. Kurihara, H. Kurihara, Tatsunori Suzuki, 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Atherosclerosis in LDL Receptor Overexpression of 15-Lipoxygenase in Vascular Endothelium Accelerates Early

H. Kurihara, A. Shaish, M. Mulkins, 2000 .

Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development

T. Asano, H. Kurihara, H. Sakoda, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation

M. Nakao, Terumasa Umemoto, T. Suda, 2021, Nature Metabolism.

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement

Yukiko Kurihara, Satoshi Arima, Koichi Nishiyama, 2011, Development.

Upregulation of endothelin-1 and adrenomedullin gene expression in the mouse endotoxin shock model.

Y. Yazaki, Y. Kurihara, H. Kurihara, 1998, Journal of cardiovascular pharmacology.

Regulation of gut-derived resistin-like molecule β expression by nutrients

Y. Uchijima, N. Horike, T. Asano, 2008 .

Association of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphism with Bone Mineral Density in Postmenopausal Japanese Women

Y. Ouchi, S. Inoue, Y. Yazaki, 2000, Calcified Tissue International.

Identification of Multiple Novel Epididymis-Specific β-Defensin Isoforms in Humans and Mice1

Y. Ouchi, H. Kurihara, S. Fukuhara, 2002, The Journal of Immunology.

Mammalian face as an evolutionary novelty

H. Kurihara, S. Kuratani, I. Werneburg, 2021, Proceedings of the National Academy of Sciences.

Establishment of mice expressing EGFP in the placode‐derived inner ear sensory cell lineage and FACS‐array analysis focused on the regional specificity of the otocyst

H. Aburatani, K. Kaga, Y. Uchijima, 2010, The Journal of comparative neurology.

Essential role of endogenous calcitonin gene‐related peptide in pain‐associated plasticity in the central amygdala

A. M. Watabe, H. Kurihara, Kei Shinohara, 2017, The European journal of neuroscience.

Donepezil Improves Cognitive Function in Mice by Increasing the Production of Insulin-Like Growth Factor-I in the Hippocampus

H. Kurihara, K. Sobue, N. Nakagata, 2009, Journal of Pharmacology and Experimental Therapeutics.

Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development.

H. Kurihara, F. Matsuzaki, Kazuaki Maruyama, 2019, Developmental biology.

Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells

Y. Kurihara, H. Kurihara, G. Alfama, 2018, bioRxiv.

Development and regeneration of hair cells

K. Kaga, H. Kurihara, P. Senn, 2007, Acta oto-laryngologica. Supplementum.

Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia.

A. Munnich, N. Katsanis, P. Ernfors, 2015, American journal of human genetics.

Vascular Smooth Muscle Cell-Directed Overexpression of Heme Oxygenase-1 Elevates Blood Pressure Through Attenuation of Nitric Oxide-Induced Vasodilation in Mice

Y. Yazaki, M. Suematsu, H. Kurihara, 2001, Circulation research.

Desalted deep-sea water improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus.

H. Kurihara, N. Nakagata, N. Harada, 2011, Translational research : the journal of laboratory and clinical medicine.

induced by methacholine and endothelin-1 Lung tissue behavior in the mouse during constriction

M. Jordana, Y. Ouchi, H. Kurihara, 2015 .

Stimulation of sensory neurons improves cognitive function by promoting the hippocampal production of insulin-like growth factor-I in mice.

H. Kurihara, N. Nakagata, N. Harada, 2009, Translational research : the journal of laboratory and clinical medicine.

Jaw muscularization requires Dlx expression by cranial neural crest cells

P. Janvier, Y. Kurihara, H. Kurihara, 2010, Proceedings of the National Academy of Sciences.

Role of endothelin-1 in stress response in the central nervous system.

R. Nagai, Y. Yazaki, Y. Kurihara, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Gene Expression of Endothelin Isoforms and Receptors in Endothelin‐1 Knockout Mice

Y. Yazaki, Y. Kurihara, H. Kurihara, 1995, Journal of cardiovascular pharmacology.

Amniogenic somatopleure: a novel origin of multiple cell lineages contributing to the cardiovascular system

Y. Kurihara, H. Kurihara, Y. Arima, 2017, Scientific Reports.

Monoclonal antibodies to endothelin: application for sandwich immunoassays.

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1990, Hybridoma.

Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration

Yukiko Kurihara, Hiroki Kurihara, Takahiro Sato, 2013, PLoS genetics.

Role of Endothelin in Central Cardiorespiratory Control: Modern and Classical Approaches

Y. Yazaki, Y. Kurihara, H. Kurihara, 1995 .

Endothelin Receptor Type A-Expressing Cell Population in the Inflow Tract Contributes to Chamber Formation

Y. Kurihara, H. Kurihara, Y. Arima, 2016 .

Endothelin activates the dihydropyridine-sensitive , voltage-dependent Ca 2 + channel in vascular smooth muscle ( Ca 2 +-channel blocker / whole-cell patch clamp / aequorin / endothelium / porcine coronary artery )

M. Yanagisawa, H. Kurihara, T. Masaki, 2003 .

Analysis of Macrophage Lineage Cells in Mice Lacking Macrophage Scavenger Receptors

T. Noda, K. Jishage, O. Ueda, 1996 .

Renal endothelin and hypertension

Y. Yazaki, Y. Kurihara, H. Kurihara, 1994, Nature.

Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.

Y. Uchijima, N. Horike, T. Asano, 2007, American journal of physiology. Cell physiology.

Transforming growth factor-β stimulates the expression of endothelin mRNA by vascular endothelial cells

Y. Yazaki, M. Yanagisawa, H. Kurihara, 1989 .

A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels

H. Kurihara, T. Masaki, K. Goto, 1988, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells

Y. Kurihara, H. Kurihara, G. Levi, 2018, Scientific Reports.

Cilostazol improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus

H. Kurihara, N. Nakagata, N. Harada, 2010, Neuropharmacology.

AMPK activation increases phosphorylation of GSK3 β and thereby reduces CRE transcriptional activity and PEPCK-C gene expression in the liver

Y. Uchijima, N. Horike, Koichi Nishiyama, 2008 .

Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.

Y. Mori, H. Matsubara, Y. Shibasaki, 1999, The Journal of clinical investigation.

Cytoplasmic calcium ion elevating factor(s) in spontaneously hypertensive rat serum.

Y. Yazaki, I. Komuro, H. Kurihara, 1990, Journal of hypertension.