B. Chabot

发表

The DNA Damage Response Pathway Regulates the Alternative Splicing of the Apoptotic Mediator Bcl-x*

L. Shkreta, L. Michelle, Johanne Toutant, 2010, The Journal of Biological Chemistry.

Identification of alternative splicing markers for breast cancer.

Sherif Abou Elela, Jean-François Lucier, J. Brosseau, 2008, Cancer research.

Cancer-associated regulation of alternative splicing

Sherif Abou Elela, Jean-François Lucier, J. Venables, 2009, Nature Structural &Molecular Biology.

Control of alternative splicing through siRNA-mediated transcriptional gene silencing

Manuel de la Mata, Sherif Abou Elela, Eduardo Eyras, 2009, Nature Structural &Molecular Biology.

NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.

P. Gendron, Philippe P Roux, B. Chabot, 2020, Cell reports.

Defective control of pre–messenger RNA splicing in human disease

L. Shkreta, B. Chabot, 2016, The Journal of cell biology.

RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues

F. Rousset, J. Brosseau, J. Tazi, 2012, Molecular and Cellular Biology.

Directing alternative splicing: cast and scenarios.

B. Chabot, 1996, Trends in genetics : TIG.

Heterogeneous Nuclear Ribonucleoprotein F/H Proteins Modulate the Alternative Splicing of the Apoptotic Mediator Bcl-x*

B. Chabot, T. Revil, D. Garneau, 2005, Journal of Biological Chemistry.

hnRNP proteins and splicing control.

L. Shkreta, B. Chabot, T. Revil, 2007, Advances in experimental medicine and biology.

Protein Kinase C-Dependent Control of Bcl-x Alternative Splicing

L. Shkreta, Johanne Toutant, B. Chabot, 2007, Molecular and Cellular Biology.

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

Mathieu Blanchette, Benoit Coulombe, Jack Greenblatt, 2007, Molecular cell.

Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing

Jean-François Fisette, B. Chabot, Rebeca D Martínez-Contreras, 2006, PLoS biology.

Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing.

Sherif Abou Elela, J. Venables, L. Shkreta, 2013, Cancer treatment and research.

SRp30c Is a Repressor of 3′ Splice Site Utilization

Martin J. Simard, B. Chabot, M. J. Simard, 2002, Molecular and Cellular Biology.

A Function for the hnRNP A1/A2 Proteins in Transcription Elongation

M. Blanchette, B. Chabot, R. Wellinger, 2015, PloS one.

Proteins Targets for the Major Human Hnrnp Multiple and Specific Mrna Processing Supplemental Material

Karine Tremblay, Sherif Abou Elela, Jean-François Lucier, 2008 .

Heterogeneous Nuclear Ribonucleoprotein K Represses the Production of Pro-apoptotic Bcl-xS Splice Isoform

Johanne Toutant, B. Chabot, T. Revil, 2009, The Journal of Biological Chemistry.

SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors

J. Manley, L. Shkreta, Johanne Toutant, 2016, Cell reports.

The RNA Splicing Response to DNA Damage

L. Shkreta, B. Chabot, Benoit Chabot, 2015, Biomolecules.

High-affinity hnRNP A1 binding sites and duplex-forming inverted repeats have similar effects on 5' splice site selection in support of a common looping out and repression mechanism.

B. Chabot, Benoit Chabot, F. Nasim, 2002, RNA.

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis

H. Soreq, M. Strong, L. Shkreta, 2018, Brain : a journal of neurology.

hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro.

B. Chabot, S. Fiset, 2001, Nucleic acids research.

Deletion of Many Yeast Introns Reveals a Minority of Genes That Require Splicing for Function Strains and Plasmids Direct Introns Displacement Strategy Growth Assays Fitness Test

S. Véronneau, B. Chabot, S. Abou Elela, 2022 .

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

S. Rowan, B. Chabot, Y. Ben-David, 1994, Proceedings of the National Academy of Sciences of the United States of America.

hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection.

Jean-François Fisette, Johanne Toutant, B. Chabot, 2010, RNA.

A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins.

B. Chabot, J. Gagné, G. Poirier, 2003, The Biochemical journal.

Structural and thermodynamical characterization of the complete p21 gene product of Max.

B. Chabot, B. Webb, P. Lavigne, 2005, Biochemistry.

The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma

Li Tao, B. Chabot, W. Hong, 2022, Nature Communications.

The nuclear matrix protein p255 is a highly phosphorylated form of RNA polymerase II largest subunit which associates with spliceosomes.

O. Bensaude, B. Chabot, M. Dubois, 1996, Nucleic acids research.

The nuclear matrix phosphoprotein p255 associates with splicing complexes as part of the [U4/U6.U5] tri-snRNP particle.

B. Chabot, M. Vincent, S. Bisotto, 1995, Nucleic Acids Research.

Targeting heterogeneous nuclear ribonucleoparticule A1 and A2 proteins by RNA interference promotes cell death in transformed but not in normal mouse cell lines.

B. Chabot, R. Wellinger, B. Lemieux, 2004, Molecular cancer therapeutics.

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

H. Soreq, M. Strong, L. Shkreta, 2018, Brain : a journal of neurology.

SRSF10: an atypical splicing regulator with critical roles in stress response, organ development, and viral replication

L. Shkreta, B. Chabot, A. Salvetti, 2021, RNA.

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency

L. Shkreta, B. Chabot, K. Clayton, 2022, Retrovirology.

The Mouse W/c‐kit Locus

A. Reith, A. Bernstein, B. Chabot, 1990, Ciba Foundation symposium.

Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs

F. Allain, C. Dominguez, B. Chabot, 2010, Nature Structural &Molecular Biology.

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production

C. Combet, F. Zoulim, B. Chabot, 2020, bioRxiv.

Recognition of mutant and cryptic 5' splice sites by the U1 small nuclear ribonucleoprotein in vitro

J. Steitz, B. Chabot, 1987, Molecular and cellular biology.

Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes

J. Steitz, B. Chabot, 1987, Molecular and cellular biology.

Effect of Low Versus High Tidal-Volume Total Liquid Ventilation on Pulmonary Inflammation

P. Micheau, J. Praud, B. Chabot, 2020, Frontiers in Physiology.

Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growth

A. Bernstein, B. Chabot, Y. Ben-David, 1992, Molecular and cellular biology.

Dimethyl Sulfoxide Affects the Selection of Splice Sites*

M. Blanchette, B. Chabot, B. Labrecque, 2001, The Journal of Biological Chemistry.

The Mouse W/c-kit Locus

A. Reith, B. Chabot, P. Dubreuil, 2007 .

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

B. Coulombe, B. Chabot, Mathieu Durand, 2017, Nature Communications.

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells

M. Tyers, J. Coulombe-Huntington, L. Shkreta, 2021, NAR cancer.

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

V. Chapman, A. Bernstein, B. Chabot, 1988, Nature.

Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions

B. Chabot, R. Klinck, C. Muchardt, 2015, Nucleic acids research.

Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals

Sherif Abou Elela, B. Chabot, R. Klinck, 2006, BMC biotechnology.

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

A. Bernstein, B. Chabot, K. Nocka, 1989, Genes & development.

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation

M. Babu, W. Houry, L. Shkreta, 2021, Viruses.

2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing.

B. Chabot, Z. Brumme, D. Grierson, 2021, ACS medicinal chemistry letters.

Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication

M. Blanchette, L. Shkreta, Johanne Toutant, 2016, Nucleic acids research.

A Parallel Synthesis Approach to the Identification of Novel Diheteroarylamide-Based Compounds Blocking HIV Replication: Potential Inhibitors of HIV-1 Pre-mRNA Alternative Splicing.

B. Chabot, P. Harrigan, P. Cheung, 2016, Journal of medicinal chemistry.

Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression

B. Chabot, S. Abou Elela, Miroslav P. Milev, 2011, Nucleic acids research.

Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

J. Tazi, Sophie Maire, B. Chabot, 2007, PLoS pathogens.

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis

B. Chabot, R. Klinck, J. Piette, 2015, BMC Cancer.

Anticancer drugs affect the alternative splicing of Bcl-x and other human apoptotic genes

Sherif Abou Elela, L. Shkreta, Johanne Toutant, 2008, Molecular Cancer Therapeutics.

The emerging role of alternative splicing in senescence and aging

B. Chabot, M. Deschênes, Mathieu Deschênes, 2017, Aging cell.

hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage

L. Shkreta, Johanne Toutant, B. Chabot, 2018, Scientific Reports.

My road to alternative splicing control: from simple paths to loops and interconnections.

B. Chabot, 2015, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Splicing of Apoptotic Regulators Complex Also Control the Alternative Proteins Associated with the Exon Junction

Sherif Abou Elela, L. Shkreta, L. Michelle, 2012 .

Proteins Associated with the Exon Junction Complex Also Control the Alternative Splicing of Apoptotic Regulators

Sherif Abou Elela, H. Le Hir, L. Shkreta, 2011, Molecular and Cellular Biology.

Antagonistic Effects of the SRp30c Protein and Cryptic 5 ′ Splice Sites on the Alternative Splicing of the Apoptotic Regulator Bcl-x*

L. Shkreta, Johanne Toutant, B. Chabot, 2008, Journal of Biological Chemistry.

Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation

Danny Bergeron, B. Chabot, F. Bachand, 2015, Molecular and Cellular Biology.

A novel mutation in the neurofibromatosis type 1 (NF1) gene promotes skipping of two exons by preventing exon definition.

M. Vidaud, D. Vidaud, B. Chabot, 2001, Journal of molecular biology.

PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.

C. Rivolta, E. Berson, B. Chabot, 2011, Human molecular genetics.

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons

Anil Wipat, Tomaz Curk, Katherine James, 2014, Nature Communications.

Multiple alternative splicing markers for ovarian cancer.

J. Venables, B. Chabot, S. Abou Elela, 2008, Cancer research.

MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation

J. Tazi, J. Venables, M. Irimia, 2013, Nature Communications.

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress

F. Dequiedt, J. Piette, B. Chabot, 2022, Nucleic acids research.

TCERG1 Regulates Alternative Splicing of the Bcl-x Gene by Modulating the Rate of RNA Polymerase II Transcription

M. Blanchette, L. Michelle, B. Chabot, 2011, Molecular and Cellular Biology.

Modulation of exon skipping by high‐affinity hnRNP A1‐binding sites and by intron elements that repress splice site utilization

M. Blanchette, B. Chabot, 1999, The EMBO journal.

An intron element modulating 5' splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1

M. Blanchette, B. Chabot, I. Lapierre, 1997, Molecular and cellular biology.

Tumor microenvironment–associated modifications of alternative splicing

Jean-François Lucier, J. Brosseau, B. Chabot, 2014, RNA.

both Normal and Cancer Tissues Mesenchymal Tissue-Specific Splicing in RBFOX2 Is an Important Regulator of

F. Rousset, J. Brosseau, J. Tazi, 2014 .

splicing associated modifications of alternative − Tumor microenvironment Material Supplemental

Jean-François Lucier, J. Brosseau, B. Chabot, 2013 .

Introns within Ribosomal Protein Genes Regulate the Production and Function of Yeast Ribosomes

Sherif Abou Elela, Jean-François Lucier, Jean-François Lucier, 2011, Cell.

Distinct Sets of Adjacent Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A1/A2 Binding Sites Control 5′ Splice Site Selection in the hnRNP A1 mRNA Precursor*

M. Blanchette, B. Chabot, S. Hutchison, 2002, The Journal of Biological Chemistry.

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

J. Steitz, D. Black, B. Chabot, 1985, Cell.

Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine

G. Batist, D. Bachvarov, B. Chabot, 2013, Modern Pathology.

Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond

L. Shkreta, B. Chabot, D. Durantel, 2021, Frontiers in Microbiology.

The 3' splice site of pre-messenger RNA is recognized by a small nuclear ribonucleoprotein.

J. Steitz, D. Black, D. LeMaster, 1985, Science.

Small interfering RNA-mediated reduction in heterogeneous nuclear ribonucleoparticule A1/A2 proteins induces apoptosis in human cancer cells but not in normal mortal cell lines.

Johanne Toutant, B. Chabot, E. Lapointe, 2003, Cancer research.

Redirecting splicing with bifunctional oligonucleotides

Jean-François Lucier, J. Brosseau, L. Shkreta, 2013, Nucleic acids research.

A Late Role for the Association of hnRNP A2 with the HIV-1 hnRNP A2 Response Elements in Genomic RNA, Gag, and Vpr Localization*[boxs]

B. Chabot, É. Cohen, A. Mouland, 2004, Journal of Biological Chemistry.

Autoantibodies in human anti‐Ro sera specifically recognize deproteinized hY5 Ro RNA

B. Chabot, H. Ménard, G. Boire, 1995, Clinical and experimental immunology.

Alternative splicing of SYK regulates mitosis and cell survival

Karine Tremblay, Sherif Abou Elela, Jean-Pierre Perreault, 2011, Nature Structural &Molecular Biology.

hnRNP I/PTB can antagonize the splicing repressor activity of SRp30c.

L. Shkreta, Johanne Toutant, B. Chabot, 2007, RNA.

The U1 Small Nuclear Ribonucleoprotein/5′ Splice Site Interaction Affects U2AF65 Binding to the Downstream 3′ Splice Site (*)

Jocelyn Côté, J. Côté, B. Chabot, 1995, The Journal of Biological Chemistry.

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

S. Dupuis, B. Chabot, R. Wellinger, 1998, Nature Genetics.

[Pre-mRNA alternative splicing in cancer: functional impact, molecular mechanisms and therapeutic perspectives].

L. Shkreta, B. Chabot, T. Revil, 2006, Bulletin du cancer.

Reprogramming Alternative Pre-messenger RNA Splicing through the Use of Protein-binding Antisense Oligonucleotides*

Sherif Abou Elela, B. Chabot, I. Dion, 2003, Journal of Biological Chemistry.

RBFOX 1 Cooperates with MBNL 1 to Control Splicing in Muscle , Including Events Altered in Myotonic Dystrophy Type 1

G. Meola, J. Puymirat, Johanne Toutant, 2018 .

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

G. Meola, J. Puymirat, Johanne Toutant, 2014, PloS one.

Control of hnRNP A1 Alternative Splicing: an Intron Element Represses Use of the Common 3′ Splice Site

B. Chabot, M. J. Simard, 2000, Molecular and Cellular Biology.

A highly stable duplex structure sequesters the 5' splice site region of hnRNP A1 alternative exon 7B.

M. Blanchette, B. Chabot, Benoit Chabot, 1997, RNA.

Modern origin of numerous alternatively spliced human introns from tandem arrays

Sherif Abou Elela, B. Chabot, Benoit Chabot, 2007, Proceedings of the National Academy of Sciences.

A Human RNA Polymerase II-containing Complex Associated with Factors Necessary for Spliceosome Assembly*

F. Robert, O. Maes, M. Blanchette, 2002, The Journal of Biological Chemistry.

Heterogeneous Nuclear Ribonucleoprotein A1 and UP1 Protect Mammalian Telomeric Repeats and Modulate Telomere Replication in Vitro *

S. Dupuis, F. Dallaire, B. Chabot, 2000, The Journal of Biological Chemistry.

Natural base-pairing interactions between 5' splice site and branch site sequences affect mammalian 5' splice site selection.

B. Chabot, J. Cote, 1997, RNA.

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

A. Kornblihtt, B. Chabot, A. Lavigueur, 1993, Genes & development.

RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells.

J. Côté, B. Chabot, B. Jasmin, 2017, The international journal of biochemistry & cell biology.

Transiently depleting RNPS1 leads to perdurable changes in alternative splicing

Johanne Toutant, B. Chabot, E. Lapointe, 2018, bioRxiv.

Heterogeneous nuclear ribonucleoprotein particle A/B proteins and the control of alternative splicing of the mammalian heterogeneous nuclear ribonucleoprotein particle A1 pre-mRNA.

B. Chabot, M. J. Simard, F. Nasim, 2003, Progress in molecular and subcellular biology.

Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA

Lincoln D. Stein, Justin G. Roy, Irina Kalatskaya, 2017, BMC Molecular Biology.

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency

L. Shkreta, B. Chabot, K. Clayton, 2022, Retrovirology.

An element in the 5' common exon of the NCAM alternative splicing unit interacts with SR proteins and modulates 5' splice site selection.

B. Chabot, M. J. Simard, J. Cote, 1999, Nucleic acids research.

Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier

J. Côté, B. Chabot, R. Klinck, 2016, PLoS genetics.

Proteolysis of splicing factors during rat and monkey cell fractionation.

B. Chabot, D. Frappier, H. La Branche, 1991, Nucleic acids research.

Differential ASF/SF2 activity in extracts from normal WI38 and transformed WI38VA13 cells.

B. Chabot, D. Frappier, H. La Branche, 1992, Nucleic acids research.

Comment on “When good transcripts go bad: artifactual RT–PCR ‘splicing’ and genome analysis”

Sherif Abou Elela, B. Chabot, D. Zhuo, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

Multiple and Specific mRNA Processing Targets for the Major Human hnRNP Proteins

Sherif Abou Elela, Jean-François Lucier, J. Venables, 2008, Molecular and Cellular Biology.

Deletion of many yeast introns reveals a minority of genes that require splicing for function.

B. Chabot, S. Abou Elela, Chushin Koh, 2008, Molecular biology of the cell.

Control of hnRNP A 1 Alternative Splicing : an Intron Element Represses Use of the Common 3 9 Splice Site

B. Chabot, M. J. Simard, 2000 .

High‐Throughput Analysis of Alternative Splicing by RT‐PCR

Sherif Abou Elela, B. Chabot, R. Klinck, 2012 .

Multiple alternative splicing markers for ovarian cancer.

J. Venables, B. Chabot, S. Abou Elela, 2008, Cancer research.

Intron Retention of DDX39A Driven by SNRPD2 is a Crucial Splicing Axis for Oncogenic MYC/Spliceosome Program in Hepatocellular Carcinoma.

B. Chabot, Qian Li, Mengqing Sun, 2024, Advanced science.

Sulfoxide Affects the Selection of Splice Sites

M. Blanchette, B. Chabot, B. Labrecque, 2001 .