A. Brooks

发表

A cell-based high-throughput screen to identify synergistic TRAIL sensitizers

Kristen M. Jacobsen, N. Booth, T. Sayers, 2009, Cancer Immunology, Immunotherapy.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow1

G. Trinchieri, R. Kastelein, J. Wigginton, 2009, The Journal of Immunology.

Bone Marrow Neuroblastoma Metastases in the Liver and and Complete Regression of Disseminated Sensitization , Tumor-Specific CTL Reactivity IL-27 and IL-2 : Enhancement of T Cell Immunologic and Therapeutic Synergy of and

G. Trinchieri, R. Kastelein, J. Wigginton, 2009 .

Increased Secretory Leukocyte Protease Inhibitor (SLPI) Production by Highly Metastatic Mouse Breast Cancer Cells

T. Sayers, A. Brooks, O. Chertov, 2014, PloS one.

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

P. Elliott, T. Sayers, A. Brooks, 2003, Blood.

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

K. Gustafson, T. Sayers, A. Brooks, 2015, Cell Death and Disease.

Bortezomib Sensitizes Human Renal Cell Carcinomas to TRAIL Apoptosis through Increased Activation of Caspase-8 in the Death-Inducing Signaling Complex

Kristen M. Jacobsen, T. Sayers, A. Brooks, 2010, Molecular Cancer Research.

Antigen presented by tumors in vivo determines the nature of CD8+ T-cell cytotoxicity.

Kristen M. Jacobsen, T. Sayers, A. Brooks, 2009, Cancer research.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.

D. Longo, T. Sayers, A. Brooks, 2015, Cancer research.

Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells.

T. Sayers, A. Brooks, P. Tewary, 2017, Journal of natural products.

T cell lysis of murine renal cancer: multiple signaling pathways for cell death via Fas

T. Sayers, A. Brooks, M. Smyth, 2000, Journal of leukocyte biology.

Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells.

J. Wigginton, T. Sayers, A. Brooks, 1998, Journal of immunology.

TFas-Mediated Pathways in Lysis by NK and Contributions of Perforin-Dependent Versus Lysis of Murine Renal Cancer : Differential Molecular Mechanisms of Immune-Mediated

J. Wigginton, T. Sayers, A. Brooks, 1998 .

Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.

Carlos A. Tristan, P. Elliott, T. Sayers, 2008, Journal of the National Cancer Institute.

The Restricted Expression of Granzyme M in Human Lymphocytes1

J. Ward, T. Sayers, A. Brooks, 2001, The Journal of Immunology.

NK Cells Use NKG2D to Recognize a Mouse Renal Cancer (Renca), yet Require Intercellular Adhesion Molecule-1 Expression on the Tumor Cells for Optimal Perforin-Dependent Effector Function1

T. Sayers, A. Brooks, M. Smyth, 2006, The Journal of Immunology.

Perforin-Dependent Effector Function on the Tumor Cells for Optimal Intercellular Adhesion Molecule-1 Expression Renal Cancer (Renca), yet Require NK Cells Use NKG2D to Recognize a Mouse

T. Sayers, A. Brooks, M. Smyth, 2006 .

PerforinTumor Regression In Vivo in the Absence of Ligand-Mediated Lysis In Vitro, But Cause Cancer Cells Using Both Perforin and Fas Tumor-Specific CTL Kill Murine Renal

T. Sayers, A. Brooks, M. Smyth, 2002 .

IFN-γ-Dependent Delay of In Vivo Tumor Progression by Fas Overexpression on Murine Renal Cancer Cells1 2

J. Wigginton, T. Sayers, A. Brooks, 2000, The Journal of Immunology.

Murine Renal Cancer Cells Progression by Fas Overexpression on-Dependent Delay of In Vivo Tumor

J. Wigginton, T. Sayers, A. Brooks, 1999 .

The Proteasome Inhibitor Bortezomib (Velcade) Sensitizes Some Human Tumor Cells to Apo2L/TRAIL‐Mediated Apoptosis

P. Elliott, T. Sayers, A. Brooks, 2005, Annals of the New York Academy of Sciences.

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

T. Sayers, A. Brooks, C. J. Henrich, 2017, Journal of medicinal chemistry.

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica.

T. Sayers, A. Brooks, P. Tewary, 2018, Phytochemistry.

Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin1

T. Sayers, A. Brooks, M. Smyth, 2002, The Journal of Immunology.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

Reduction of the antiapoptotic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis

T. Sayers, A. Brooks, 2005, Cancer Immunology, Immunotherapy.

Inhibition of Fas (CD95) expression and Fas-mediated apoptosis by oncogenic Ras.

T. Sayers, A. Brooks, R. Fenton, 1998, Cancer research.

IFN-gamma-dependent delay of in vivo tumor progression by Fas overexpression on murine renal cancer cells.

J. Wigginton, T. Sayers, A. Brooks, 2000, Journal of immunology.

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

R. Chari, T. Sayers, A. Brooks, 2021, Cancer Research.

Human Lymphocytes The Restricted Expression of Granzyme M in

Jerrold M. Ward, Gordon W. Wiegand, Janice M. Kelley, 2013 .

Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.

T. Sayers, A. Brooks, M. Smyth, 2003, Cancer research.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

TRAIL-mediated apoptosis by reducing levels of c-FLIP The proteasome inhibitor PS-341 sensitizes neoplastic cells to

P. Elliott, T. Sayers, A. Brooks, 2013 .

Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis Is an Important Endogenous Mechanism for Resistance to Liver Metastases in Murine Renal Cancer 1

T. Sayers, A. Brooks, M. Smyth, 2002 .

Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma.

T. Sayers, A. Brooks, P. Tewary, 2021, Journal of natural products.

Regulation of inducible nitric oxide synthase expression in IFN-gamma-treated murine macrophages cultured under hypoxic conditions.

A. Brooks, G. Melillo, L. Varesio, 1996, Journal of immunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

TRAIL-mediated apoptosis by reducing levels of c-FLIP The proteasome inhibitor PS-341 sensitizes neoplastic cells to

P. Elliott, T. Sayers, A. Brooks, 2013 .