J. Mcmahon

发表

A cell-based high-throughput screen to identify synergistic TRAIL sensitizers

Kristen M. Jacobsen, N. Booth, T. Sayers, 2009, Cancer Immunology, Immunotherapy.

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions.

J. Mcmahon, P. Seeberger, D. Ratner, 2004, Chemistry & biology.

T7 lytic phage‐displayed peptide libraries exhibit less sequence bias than M13 filamentous phage‐displayed peptide libraries

Lee Makowski, L. Makowski, J. Mcmahon, 2006, Proteomics.

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

Alexander Wlodawer, Barry R O'Keefe, Barbara Giomarelli, 2006, Structure.

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

S. Subramaniam, A. Wlodawer, J. Meyerson, 2015, Retrovirology.

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

L K Pannell, L. Pannell, K. Gustafson, 1997, Antimicrobial agents and chemotherapy.

Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.*

Barry R O'Keefe, Robert W Buckheit, Scott Bringans, 2005, Journal of Biological Chemistry.

Influence of priming with 5-hydroxytryptophan on APUD characteristics in human small cell lung cancer cell lines

A. Gazdar, J. Mcmahon, K. Becker, 2007, Lung.

Metabolic activation and cytotoxicity of 4-ipomeanol in human non-small cell lung cancer lines.

M. Boyd, J. Mcmahon, M. Falzon, 1986, Cancer research.

Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

M. Boyd, P. Boyer, S. Hughes, 1993, Journal of virology.

HIV-inhibitory coumarins from latex of the tropical rainforest tree Calophyllum teysmannii var. inophylloide

K. Gustafson, M. Boyd, J. Mcmahon, 1994 .

Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis.

M. Boyd, M. Stahl, J. Mcmahon, 1997, Journal of natural products.

Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600.

B. Shen, N. Colburn, J. Mcmahon, 2011, Journal of natural products.

Anti-HIV michellamines from Ancistrocladus korupensis.

M. Boyd, J. Mcmahon, G. Bringmann, 1994, Journal of medicinal chemistry.

The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1

M. Boyd, J. Mcmahon, Toshiyuki Mori, 2002, AIDS.

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.

Kristina M. Cook, K. Gustafson, D. Venzon, 2016, Journal of natural products.

Neamphamide A, a new HIV-inhibitory depsipeptide from the Papua New Guinea marine sponge Neamphius huxleyi.

L. Pannell, K. Gustafson, M. Boyd, 2004, Journal of natural products.

Identification of Compounds by High-Content Screening That Induce Cytoplasmic to Nuclear Localization of a Fluorescent Estrogen Receptor α Chimera and Exhibit Agonist or Antagonist Activity In Vitro

Jason R. Evans, G. Hager, E. Goncharova, 2014, Journal of biomolecular screening.

Development of an image analysis screen for estrogen receptor alpha (ERα) ligands through measurement of nuclear translocation dynamics

G. Hager, E. Goncharova, J. Mcmahon, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells.

L. Morris, J. Mcmahon, E. Gray, 2012, Virology.

Rat alpha-fetoprotein: in vitro production of four molecular variants by clonal cell lines.

J. Mcmahon, P. Kelleher, C. J. Smith, 1977, Biochemical and biophysical research communications.

High Throughput Screening for Cyanovirin-N Mimetics Binding to HIV-1 gp4l

M. Boyd, J. Mcmahon, D. Robbins, 2002, Journal of biomolecular screening.

Inhibition of thrombin-induced platelet aggregation using human single-chain Fv antibodies specific for TREM-like transcript-1

J. Mcmahon, Toshiyuki Mori, Barbara Giomarelli, 2006, Thrombosis and Haemostasis.

Xenobiotic-metabolizing enzyme activity in human non-small-cell derived lung cancer cell lines.

J. Mcmahon, M. Falzon, H. Schuller, 1986, Biochemical pharmacology.

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

K. Gustafson, T. Sayers, A. Brooks, 2015, Cell Death and Disease.

A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1.

Z. Szallasi, K. Gustafson, O. Weislow, 1992, Journal of medicinal chemistry.

The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

K. Gustafson, M. Boyd, S. Hughes, 1992, Journal of medicinal chemistry.

Michellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanisms

M. Boyd, J. Mcmahon, C. Lackman-Smith, 1995, Antimicrobial agents and chemotherapy.

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

M. Bray, J. Mcmahon, J. Huggins, 2014, Antiviral research.

Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus

Y. Takebe, K. Ramessar, J. Mcmahon, 2012, PloS one.

A capillary electrophoretic assay for ribonuclease H activity.

S. L. Le Grice, J. Mcmahon, R. Crouch, 2004, Analytical biochemistry.

Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids.

K. Gustafson, J. Mcmahon, C. J. Henrich, 2010, Bioorganic & medicinal chemistry letters.

Circulins A and B. Novel human immunodeficiency virus (HIV)-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia.

L. Pannell, K. Gustafson, M. Boyd, 1994 .

CHAPTER 14 – METABOLIC ACTIVATION AND BIOLOGICAL EFFECTS OF NITROSAMINES IN THE MAMMALIAN LUNG

J. Mcmahon, M. Falzon, H. Schuller, 1993 .

Metabolic activation and biological effects of nitrosamines in the mammalian lung.

J. Mcmahon, M. Falzon, H. Schuller, 1990, Pharmacology & therapeutics.

A novel phorbol ester from Excoecaria agallocha.

M. Boyd, J. Mcmahon, D. Newman, 1995, Journal of natural products.

Distribution and subcellular localization of a hepatic proliferation inhibitor in rat liver.

J. Mcmahon, L. Malan-Shibley, P. Iype, 1984, The Journal of biological chemistry.

Inhibition of reverse transcriptase of human immunodeficiency virus type 1 and chimeric enzymes of human immunodeficiency viruses types 1 and 2 by two novel non‐nucleoside inhibitors

J. Mcmahon, A. Hizi, T. Rubinek, 1994, FEBS letters.

Metabolism of Arachidonic Acid in Human Lung Cancer Cell Lines1

M. Boyd, J. Mcmahon, S. Lau, 2006 .

Metabolism of arachidonic acid in human lung cancer cell lines.

M. Boyd, J. Mcmahon, S. Lau, 1987, Cancer research.

Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius.

N. Colburn, J. Mcmahon, C. J. Henrich, 2011, Journal of natural products.

Specific inhibition of proliferation of nonmalignant rat hepatic cells by a factor from rat liver.

J. Mcmahon, P. Iype, 1980, Cancer research.

Potent anti-HIV activity of scytovirin domain 1 peptide

J. Mcmahon, R. Byrd, B. O’Keefe, 2006, Peptides.

Role of TGF‐Beta in Normal Differentiation and Oncogenesis in Rat Liver

S. Thorgeirsson, J. Mcmahon, R. Evarts, 1989, Molecular carcinogenesis.

Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box.

K. Gustafson, J. Mcmahon, D. Ferreira, 2018, Chemical Science.

Lack of a functional VHL gene product sensitizes renal cell carcinoma cells to the apoptotic effects of the protein synthesis inhibitor verrucarin A.

W. Linehan, J. Mcmahon, G. Woldemichael, 2012, Neoplasia.

Identification and evaluation of soft coral diterpenes as inhibitors of HIF-2α induced gene expression.

K. Gustafson, W. Linehan, J. Mcmahon, 2011, Bioorganic & medicinal chemistry letters.

A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum.

W. Linehan, J. Mcmahon, H. Bokesch, 2011, Chemical & pharmaceutical bulletin.

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

S. L. Le Grice, J. Mcmahon, I. Gorshkova, 2005, Nucleic acids research.

Novel Intrapulmonar } ' Model for Orthotopic Propagation of Human Lung Cancers in Athymic Nude Mice

M. Boyd, R. Shoemaker, M. Bohlman, 2006 .

New monoterpene glycosides and phenolic compounds from Distylium racemosum and their inhibitory activity against ribonuclease H.

S. L. Le Grice, J. Mcmahon, Jeong Ah Kim, 2011, Bioorganic & medicinal chemistry letters.

HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.

S. L. Le Grice, J. Mcmahon, J. Beutler, 2008, Journal of natural products.

Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells.

W Marston Linehan, W. Linehan, J. Mcmahon, 2011, Cancer research.

Identification and evaluation of soft coral diterpenes as inhibitors of HIF-2α induced gene expression.

K. Gustafson, W. Linehan, J. Mcmahon, 2011, Bioorganic & medicinal chemistry letters.

Initial studies on the cellular pharmacology of 2',3-dideoxycytidine, an inhibitor of HTLV-III infectivity.

H. Mitsuya, S. Broder, J. Mcmahon, 1986, Biochemical pharmacology.

Initial mechanistic studies with merbarone (NSC 336628).

J. Mcmahon, D. Cooney, J. Covey, 1985, Biochemical pharmacology.

Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.

N. Colburn, J. Pelletier, E. Goncharova, 2009, Journal of natural products.

New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.

M. Boyd, J. Mcmahon, R. Fuller, 1996, Journal of natural products.

Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4.

K. Gustafson, N. Colburn, Cheryl L. Thomas, 2011, Journal of natural products.

Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4

Jason R. Evans, N. Colburn, Cheryl L. Thomas, 2010, Journal of biomolecular screening.

Adaptation of a low‐power stereomicroscope to scan cell colonies labelled with fluorescein isothiocyanate

J. Mcmahon, P. Iype, P. Thomas Iype, 1981, Journal of microscopy.

Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.

S. Pomponi, L. Pannell, M. Boyd, 1997, European journal of biochemistry.

Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.

Christian Griesinger, Han Sun, Curtis J Henrich, 2012, Journal of natural products.

A semiautomated multiparameter approach for anti-HIV drug screening.

M. Boyd, J. Mcmahon, R. Gulakowski, 1991, Journal of virological methods.

HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. [Erratum to document cited in CA117(11):108101g]

K. Gustafson, M. Boyd, S. Hughes, 1993 .

Biological and biochemical anti-HIV activity of the benzothiadiazine class of nonnucleoside reverse transcriptase inhibitors.

M. Boyd, J. Mcmahon, W. Decker, 1994, Antiviral research.

Novel alkaloids from the tropical plant Ancistrocladus abbreviatus inhibit cell killing by HIV-1 and HIV-2.

M. Boyd, J. Mcmahon, G. Cragg, 1991, Journal of medicinal chemistry.

Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.

K. Gustafson, M. Boyd, J. Mcmahon, 1996, The Journal of pharmacology and experimental therapeutics.

Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B.

M. Boyd, J. Mcmahon, R. Fuller, 1996, Journal of medicinal chemistry.

Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors

M. Boyd, S. Hughes, M. Shaharabany, 1993, Antimicrobial Agents and Chemotherapy.

Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.

M. Boyd, J. Mcmahon, M. Currens, 1996, The Journal of pharmacology and experimental therapeutics.

Caulibugulones A-F, novel cytotoxic isoquinoline quinones and iminoquinones from the marine bryozoan Caulibugula intermis.

K. Gustafson, J. Mcmahon, J. Kelley, 2004, Journal of natural products.

Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase

O. Weislow, J. Mcmahon, R. Schultz, 1993, Antimicrobial Agents and Chemotherapy.

Corrigendum to ‘Stellettapeptins A and B, HIV-inhibitory cyclic depsipeptides from the marine sponge Stelletta sp.’ [Tetrahedron Lett. 56(28) (2015) 4215–4219]

K. Gustafson, M. Rashid, J. Mcmahon, 2015 .

Isolation and characterization of anti‐HIV peptides from Dorstenia contrajerva and Treculia obovoidea

J. Mcmahon, J. Beutler, B. O’Keefe, 2004, FEBS letters.

Monanchorin, a bicyclic alkaloid from the sponge Monanchora ungiculata.

J. Mcmahon, T. Mckee, K. M. Meragelman, 2004, Journal of natural products.

Gymnangiamide, a cytotoxic pentapeptide from the marine hydroid Gymnangium regae.

L. Pannell, K. Gustafson, M. Boyd, 2004, The Journal of organic chemistry.

Inhibition of N-nitrosodiethylamine-induced respiratory tract carcinogenesis by piperonylbutoxide in hamsters.

J. Mcmahon, H. Schuller, 1985, Cancer research.

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina.

W. M. Hewitt, K. Gustafson, J. Mcmahon, 2017, Organic letters.

Stellettapeptins A and B, HIV-inhibitory cyclic depsipeptides from the marine sponge Stelletta sp.

K. Gustafson, M. Rashid, J. Mcmahon, 2015, Tetrahedron letters.

Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4

K. Gustafson, N. Colburn, Cheryl L. Thomas, 2014, Marine drugs.

Growth inhibition of human colon carcinoma cells by sesquiterpenoids and tetralones of Zygogynum calothyrsum.

D. Covell, J. Mcmahon, J. Beutler, 2013, Journal of natural products.

Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2.

Curtis J Henrich, K. Gustafson, S. Bates, 2011, Journal of natural products.

HIV inhibitory natural products. 6. The peltatols, novel HIV-inhibitory catechol derivatives from Pothomorphe peltata

L. Pannell, K. Gustafson, M. Boyd, 1992 .

Anti-HIV and cytotoxic alkaloids from Buchenavia capitata.

M. Boyd, J. Mcmahon, G. Cragg, 1992, Journal of natural products.

The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea

Gordon M. Cragg, John W. Blunt, Murray H. G. Munro, 1992 .

HIV inhibitory natural products. 3. Diterpenes from and

K. Gustafson, M. Boyd, J. Clardy, 1991 .

Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture.

J. Hartley, J. Mcmahon, Toshiyuki Mori, 2006, Protein expression and purification.

Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.

A. Wlodawer, J. Mcmahon, I. Botos, 2006, Protein expression and purification.

HIV inhibitory natural products. 11. Structure, absolute stereochemistry, and synthesis of conocurvone, a potent, novel HIV-inhibitory naphthoquinone trimer from a Conospermum sp

L. Pannell, K. Gustafson, L. Decosterd, 1993 .

Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers.

T. Sayers, Cheryl L. Thomas, J. Mcmahon, 2010, Journal of natural products.

Stelliosphaerols A and B, Sesquiterpene-Polyol Conjugates from an Ecuadorian Fungal Endophyte.

K. Gustafson, S. Strobel, J. Mcmahon, 2015, Journal of natural products.

Isobutylhydroxyamides from the pericarp of Nepalese Zanthoxylum armatum inhibit NF1-defective tumor cell line growth.

K. Reilly, J. Mcmahon, C. J. Henrich, 2013, Journal of natural products.

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.

Yili Yang, A. Weissman, J. Mcmahon, 2008, Bioorganic & medicinal chemistry.

Isolation, structural elucidation, and absolute stereochemistry of enigmazole A, a cytotoxic phosphomacrolide from the Papua New Guinea marine sponge Cinachyrella enigmatica.

Megan L. Peach, L. Pannell, K. Gustafson, 2010, Journal of the American Chemical Society.

Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling

K. Gustafson, D. Morrison, J. Mcmahon, 2018, Front. Chem..

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

D. Meyerholz, J. Mcmahon, C. Wohlford-Lenane, 2009, Journal of Virology.

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

David C. Montefiori, Barry R. O'Keefe, D. Montefiori, 2009, Proceedings of the National Academy of Sciences.

Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold.

Leo A. Joyce, K. Gustafson, W. Schafer, 2016, The Journal of organic chemistry.

Alpha‐fetoprotein: Is the Pattern of Concanavalin A‐affinity Molecular Variants a Marker for Synthesis by Neoplastic Cells in the Rat?

J. Mcmahon, P. Kelleher, M. Barus, 1978 .

Method for collecting blood from fetal and newborn rats.

J. Mcmahon, C. Smith, 1977, Laboratory animal science.

Hepatic proliferation inhibitor

J. Mcmahon, P. Thomas Iype, 2004, Molecular and Cellular Biochemistry.

Purification and properties of a rat liver protein that specifically inhibits the proliferation of nonmalignant epithelial cells from rat liver.

J. Mcmahon, J. Farrelly, P. Iype, 1982, Proceedings of the National Academy of Sciences of the United States of America.

A rapid in vitro method for the evaluation of potential antitumor drugs requiring metabolic activation by hepatic S9 enzymes.

R. Shoemaker, J. Mcmahon, G. Steinmann, 1989, Biochemical pharmacology.

Arabinosyl-5-a/acytosine: Mechanisms of Native and Acquired Resistance1

Gurpreet, J. Mcmahon, J. Balzarini, 2006 .

Arabinosyl-5-azacytosine: mechanisms of native and acquired resistance.

M. Cohen, J. Mcmahon, J. Balzarini, 1986, Cancer research.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

New candidaspongiolides, tedanolide analogues that selectively inhibit melanoma cell growth.

M. Hall, J. Mcmahon, T. Mckee, 2011, Organic letters.

Structural assignment of poecillastrins B and C, macrolide lactams from the deep-water Caribbean sponge Poecillastra species.

K. Gustafson, M. Rashid, J. Mcmahon, 2007, Journal of natural products.

HIV-Inhibitory Gallotannins from Lepidobotrys staudtii

M. Boyd, J. Mcmahon, M. Currens, 1996 .

Thiazolobenzimidazole: biological and biochemical anti-retroviral activity of a new nonnucleoside reverse transcriptase inhibitor.

J. Mcmahon, M. Hollingshead, W. Decker, 1993, Antiviral research.

Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups.

M. Boyd, J. Mcmahon, W. Decker, 1995, Antiviral research.

Oxathiin carboxanilide, a potent inhibitor of human immunodeficiency virus reproduction.

W. A. Harrison, M. Boyd, O. Weislow, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Deguelins, Natural Product Modulators of NF1-Defective Astrocytoma Cell Growth Identified by High-Throughput Screening of Partially Purified Natural Product Extracts.

Karlyne M. Reilly, K. Gustafson, K. Reilly, 2015, Journal of natural products.

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1

K. Gustafson, N. Colburn, B. Brüne, 2012, PloS one.

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

Fa Liu, Marc C. Nicklaus, Dong-Hee Lee, 2009, Nature Structural &Molecular Biology.

Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.

Qing-Rong Chen, Sean Davis, Javed Khan, 2011, Journal of the National Cancer Institute.

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

A. Wlodawer, Z. Dauter, Cheryl L. Thomas, 2010, Structure.

Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.

S. Thorgeirsson, J. Mcmahon, M. Song, 1986, Cancer research.

Identification of Inhibitors for MDM2 Ubiquitin Ligase Activity from Natural Product Extracts by a Novel High-Throughput Electrochemiluminescent Screen

Pankaj Oberoi, Jirouta Kitagaki, John A. Beutler, 2008, Journal of biomolecular screening.

High‐throughput Screening for Identification of Inhibitors of EpCAM‐Dependent Growth of Hepatocellular Carcinoma Cells

Curtis J Henrich, Zhipeng Yu, Jason R. Evans, 2013, Chemical biology & drug design.

Botryllamides: natural product inhibitors of ABCG2.

Suneet Shukla, Kentaro Takada, Curtis J Henrich, 2009, ACS chemical biology.

A High-Throughput Cell-Based Assay for Inhibitors of ABCG2 Activity

Michael Dean, Curtis J Henrich, S. Bates, 2006, Journal of biomolecular screening.

New inhibitors of ABCG2 identified by high-throughput screening

Michael Dean, Suneet Shukla, Curtis J Henrich, 2007, Molecular Cancer Therapeutics.

New inhibitors of ABCG 2 identified by high-throughput screening

S. Bates, J. Mcmahon, C. J. Henrich, 2007 .

Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α.

Kristina M. Cook, K. Gustafson, J. Mcmahon, 2015, Journal of the American Chemical Society.

Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

K. Ramessar, J. Mcmahon, N. B. da Cunha, 2015, Plant biotechnology journal.

Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II).

Kristina M. Cook, J. Mcmahon, A. Hamilton, 2015, European journal of medicinal chemistry.

Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells*

J. Mcmahon, P. Grohar, G. Woldemichael, 2016, The Journal of Biological Chemistry.

Chlorinated englerins with selective inhibition of renal cancer cell growth.

J. Mcmahon, J. Beutler, R. Akee, 2012, Journal of natural products.

Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site

L. Morris, P. Moore, J. Mcmahon, 2011, Journal of Virology.

A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H.

S. L. Le Grice, J. Mcmahon, K. Bae, 2007, Journal of natural products.

Characterization of pomiferin triacetate as a novel mTOR and translation inhibitor.

K. Gustafson, Z. Dong, N. Colburn, 2014, Biochemical pharmacology.

HIV-inhibitory natural products. 11. Comparative studies of sulfated sterols from marine invertebrates.

J. Mcmahon, R. Riccio, M. V. D’Auria, 1994, Journal of medicinal chemistry.

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

L. Morris, P. Moore, M. Nonyane, 2013, Virology.

Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner.

M. Boyd, J. Mcmahon, B. O’Keefe, 2001, Molecular pharmacology.

Recombinant production of cyanovirin-N, a potent human immunodeficiency virus-inactivating protein derived from a cultured cyanobacterium.

L. Pannell, K. Gustafson, M. Boyd, 1998, Protein expression and purification.

Preferential metabolism of N-nitrosodiethylamine by two cell lines derived from human pulmonary adenocarcinomas.

A. Gazdar, J. Mcmahon, M. Falzon, 1986, Carcinogenesis.

Mannose-rich glycosylation patterns on HIV-1 subtype C gp 120 and sensitivity to the lectins

S. Karim, L. Morris, P. Moore, 2011 .

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.

S. Karim, L. Morris, P. Moore, 2010, Virology.

The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors.

J. Mcmahon, R. Byrd, P. Seeberger, 2007, Journal of molecular biology.

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin† ‡

R. Dwek, A. Wlodawer, M. Wormald, 2007, Proteins.

Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum.

L. Pannell, K. Gustafson, M. Boyd, 1997, Biochemical and biophysical research communications.

AIDS-Antiviral Natural Products Research at The U.S. National Cancer Institute

K. Gustafson, M. Boyd, J. Mcmahon, 1992 .

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

D. Meyerholz, J. Mcmahon, C. Wohlford-Lenane, 2010, Journal of Virology.

Resistance of Human Immunodeficiency Virus Type 1 to the High-Mannose Binding Agents Cyanovirin N and Concanavalin A

L. Stamatatos, E. De Clercq, C. Pannecouque, 2005, Journal of Virology.

Multivalent interactions with gp120 are required for the anti‐HIV activity of Cyanovirin

J. Mcmahon, G. Ghirlanda, Barbara Giomarelli, 2009, Biopolymers.

The HIV-inactivating protein, cyanovirin-N, does not block gp120-mediated virus-to-cell binding.

K. Nagashima, M. Boyd, J. Mcmahon, 1998, Biochemical and biophysical research communications.

Construction and enhanced cytotoxicity of a [cyanovirin-N]-[Pseudomonas exotoxin] conjugate against human immunodeficiency virus-infected cells.

K. Gustafson, M. Boyd, R. Shoemaker, 1997, Biochemical and biophysical research communications.

Analysis of sequence requirements for biological activity of cyanovirin-N, a potent HIV (human immunodeficiency virus)-inactivating protein.

L. Pannell, K. Gustafson, M. Boyd, 1997, Biochemical and Biophysical Research Communications - BBRC.

Development of a Cyanovirin-N-HIV-1 gpl20 Binding Assay for High Throughput Screening of Natural Product Extracts by Time-Resolved Fluorescence

M. Boyd, J. Mcmahon, J. Beutler, 2000, Journal of biomolecular screening.

Antiviral and Antitumor Plant Metabolites

M. Boyd, R. Shoemaker, J. Mcmahon, 1995 .

Discovery of a Novel Potent Inhibitor of HIV Infection

W. A. Harrison, M. Boyd, J. Mcmahon, 1991 .

Anti-HIV Alkaloids from Toddalia asiatica

K. Gustafson, M. Boyd, M. Rashid, 1995 .

Isolation and characterization of adociavirin, a novel HIV‐inhibitory protein from the sponge Adocia sp. 1

M. Boyd, J. Mcmahon, J. Beutler, 1998, FEBS letters.

Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.

M. Boyd, R. Shoemaker, D. Vistica, 1996, The Journal of pharmacology and experimental therapeutics.

Differential metabolism of arachidonic acid in human lung cancer cell lines (HLCCL)

J. Mcmahon, S. Lau, M. McMenamin, 1985 .

Chapter Three ANTIVIRAL AND ANTITUMOR PLANT METABOLITES

M. Boyd, R. Shoemaker, J. Mcmahon, 1995 .

Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV).

K. Gustafson, M. Boyd, J. Mcmahon, 1997, Antiviral research.

Natural Products Active in Aberrant c‐Kit Signaling

K. Gustafson, E. Goncharova, J. Mcmahon, 2007, Chemical biology & drug design.

A High-Throughput Cell-Based Assay to Identify Specific Inhibitors of Transcription Factor AP-1

N. Colburn, E. Goncharova, J. Mcmahon, 2007, Journal of biomolecular screening.

Differential activation of 4-ipomeanol by human lung cancer cell lines (HLCCL)

M. Boyd, J. Mcmahon, M. Falzon, 1985 .

Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula.

N. Colburn, J. Mcmahon, C. J. Henrich, 2011, Journal of natural products.

Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii.

K. Gustafson, N. Colburn, J. Mcmahon, 2011, Bioorganic & medicinal chemistry letters.

A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits”

K. Gustafson, N. Colburn, J. Mcmahon, 2009, Molecular Cancer Therapeutics.

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

Fa Liu, Dong-Hee Lee, Jung-Eun Park, 2009, Nature Structural &Molecular Biology.

Sulfonic Acid Dyes: Inhibition of the Human Immunodeficiency Virus and Mechanism of Action

O. Weislow, J. Mcmahon, M. Hollingshead, 1992, Journal of acquired immune deficiency syndromes.

Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction.

O. Weislow, J. Mcmahon, D. Clanton, 1994, Journal of medicinal chemistry.

Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera.

K. Gustafson, J. Mcmahon, C. J. Henrich, 2012, Journal of natural products.

Development of a Cell-Based Reporter Assay for Screening of Inhibitors of Hypoxia-Inducible Factor 2-Induced Gene Expression

W. Linehan, W. Linehan, J. Mcmahon, 2006, Journal of biomolecular screening.

Steroidal Alkaloids from the Marine Sponge Corticium niger That Inhibit Growth of Human Colon Carcinoma Cells

K. Gustafson, D. Covell, J. Mcmahon, 2014, Journal of natural products.

Interactive laser cytometric analysis of retroviral protein expression in HIV-infected lymphocytic cell lines.

M. Boyd, O. Weislow, R. Kiser, 1990, AIDS research and human retroviruses.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

Lack of Correlation between the Response to a Proliferation Inhibitor and Other Transformation Markers in a Mutant Liver Cell Line 1

J. Mcmahon, P. Type, 2006 .

Isolation and structure of pedilstatin from a Republic of maldives Pedilanthus sp.1

M. Boyd, J. Mcmahon, P. Blumberg, 2002 .

Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells.

Karlyne M. Reilly, K. Reilly, J. Mcmahon, 2014, Phytochemistry letters.

Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library

Lee Makowski, L. Makowski, J. Mcmahon, 2007, BMC biotechnology.

New colorimetric cytotoxicity assay for anticancer-drug screening.

D. Scudiero, M. Boyd, A. Monks, 1990, Journal of the National Cancer Institute.

Characterization of rat alveolar type II cells in vitro by immunological, biochemical, and morphological criteria.

J. Mcmahon, G. Singh, S. Katyal, 1986, Experimental lung research.

Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti‐HIV microbicide

J. Mcmahon, Yonghou Jiang, K. Palmer, 2007, Journal of medical primatology.

Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp.

M. Boyd, J. Mcmahon, P. Blumberg, 2002, Journal of natural products.

Feasibility of cellular microencapsulation technology for evaluation of anti-human immunodeficiency virus drugs in vivo.

O. Weislow, R. Kiser, R. Shoemaker, 1990, Journal of the National Cancer Institute.