C. J. Henrich

发表

A cell-based high-throughput screen to identify synergistic TRAIL sensitizers

Kristen M. Jacobsen, N. Booth, T. Sayers, 2009, Cancer Immunology, Immunotherapy.

Microwave-based reaction screening: tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers.

Katharine J. Cahill, N. Colburn, C. J. Henrich, 2011, The Journal of organic chemistry.

Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods.

Brice A P Wilson, K. Gustafson, C. J. Henrich, 2020, Phytochemistry.

Isolation and characterization of a glycopeptide from human senescent erythrocytes.

C. J. Henrich, D. Aminoff, 1983, Carbohydrate research.

Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600.

B. Shen, N. Colburn, J. Mcmahon, 2011, Journal of natural products.

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.

Kristina M. Cook, K. Gustafson, D. Venzon, 2016, Journal of natural products.

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

T. Sayers, Cheryl L. Thomas, C. J. Henrich, 2018, Scientific Reports.

Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

K. Gustafson, S. Bates, C. J. Henrich, 2019, Cancer biology & therapy.

A growth factor for cardiac myocytes is produced by cardiac nonmyocytes.

C. Long, P. Simpson, C. J. Henrich, 1991, Cell regulation.

Introduction of Small Molecules into Cells Using a Transient Cell Permeabilization System

C. J. Henrich, 1994 .

A Microplate-Based Nonradioactive Protein Synthesis Assay: Application to TRAIL Sensitization by Protein Synthesis Inhibitors

C. J. Henrich, 2016, PloS one.

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

K. Gustafson, T. Sayers, A. Brooks, 2015, Cell Death and Disease.

Using Protein Kinase and Protein Phosphatase Inhibitors to Dissect Protein Phosphorylation Pathways

J. Karaszkiewicz, C. J. Henrich, 1997, Current protocols in immunology.

Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids.

K. Gustafson, J. Mcmahon, C. J. Henrich, 2010, Bioorganic & medicinal chemistry letters.

A protein kinase C isozyme is translocated to cytoskeletal elements on activation.

P. Simpson, C. J. Henrich, D. Mochly‐Rosen, 1990, Cell regulation.

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea

K. Gustafson, C. J. Henrich, R. Cichewicz, 2021, Molecules.

Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius.

N. Colburn, J. Mcmahon, C. J. Henrich, 2011, Journal of natural products.

Agrowth factor forcardiac myocytesisproduced bycardiac nonmyocytes

C. Long, C. J. Henrich, 1991 .

Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction

P. Alexander, D. Morrison, E. Goncharova, 2021, Molecular Cancer Therapeutics.

National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

Jason R. Evans, K. Gustafson, C. J. Henrich, 2020, ACS chemical biology.

Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.

N. Colburn, J. Pelletier, E. Goncharova, 2009, Journal of natural products.

Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4.

K. Gustafson, N. Colburn, Cheryl L. Thomas, 2011, Journal of natural products.

Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4

Jason R. Evans, N. Colburn, Cheryl L. Thomas, 2010, Journal of biomolecular screening.

Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.

Christian Griesinger, Han Sun, Curtis J Henrich, 2012, Journal of natural products.

Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4

N. Colburn, B. Brüne, C. J. Henrich, 2016, PloS one.

Creating and screening natural product libraries.

Tanja Grkovic, Curtis J Henrich, Brice A P Wilson, 2020, Natural product reports.

Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4

K. Gustafson, N. Colburn, Cheryl L. Thomas, 2014, Marine drugs.

Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2.

Curtis J Henrich, K. Gustafson, S. Bates, 2011, Journal of natural products.

Matching the power of high throughput screening to the chemical diversity of natural products.

Curtis J Henrich, John A Beutler, C. J. Henrich, 2013, Natural product reports.

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

T. Sayers, A. Brooks, C. J. Henrich, 2017, Journal of medicinal chemistry.

Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers.

T. Sayers, Cheryl L. Thomas, J. Mcmahon, 2010, Journal of natural products.

Isobutylhydroxyamides from the pericarp of Nepalese Zanthoxylum armatum inhibit NF1-defective tumor cell line growth.

K. Reilly, J. Mcmahon, C. J. Henrich, 2013, Journal of natural products.

Differential acute and chronic response of protein kinase C in cultured neonatal rat heart myocytes to alpha 1-adrenergic and phorbol ester stimulation.

P. Simpson, C. J. Henrich, 1988, Journal of molecular and cellular cardiology.

NMR Characterization of Rearranged Staurosporine Aglycone Analogues from the Marine Sponge Damiria sp.

K. Gustafson, C. J. Henrich, P. Kittakoop, 2019, Magnetic resonance in chemistry : MRC.

Elucidation of Spirodactylone, a Polycyclic Alkaloid from the Sponge Dactylia sp., and Nonenzymatic Generation from the Co-metabolite Denigrin B.

K. Gustafson, C. J. Henrich, H. Bokesch, 2019, Organic letters.

Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold.

Leo A. Joyce, K. Gustafson, W. Schafer, 2016, The Journal of organic chemistry.

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

T. Sayers, Cheryl L. Thomas, C. J. Henrich, 2018, Scientific Reports.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

Deguelins, Natural Product Modulators of NF1-Defective Astrocytoma Cell Growth Identified by High-Throughput Screening of Partially Purified Natural Product Extracts.

Karlyne M. Reilly, K. Gustafson, K. Reilly, 2015, Journal of natural products.

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1

K. Gustafson, N. Colburn, B. Brüne, 2012, PloS one.

Inhibition of wnt/β-catenin Signaling in Hepatocellular Carcinoma by an Antipsychotic Drug Pimozide

X. Wang, C. J. Henrich, Zhipeng Yu, 2016, International journal of biological sciences.

High‐throughput Screening for Identification of Inhibitors of EpCAM‐Dependent Growth of Hepatocellular Carcinoma Cells

Curtis J Henrich, Zhipeng Yu, Jason R. Evans, 2013, Chemical biology & drug design.

Synthesis and structure-activity relationship of botryllamides that block the ABCG2 multidrug transporter.

K. Gustafson, C. J. Henrich, N. Imamura, 2010, Bioorganic & medicinal chemistry letters.

Botryllamides: natural product inhibitors of ABCG2.

Suneet Shukla, Kentaro Takada, Curtis J Henrich, 2009, ACS chemical biology.

A High-Throughput Cell-Based Assay for Inhibitors of ABCG2 Activity

Michael Dean, Curtis J Henrich, S. Bates, 2006, Journal of biomolecular screening.

New inhibitors of ABCG2 identified by high-throughput screening

Michael Dean, Suneet Shukla, Curtis J Henrich, 2007, Molecular Cancer Therapeutics.

New inhibitors of ABCG 2 identified by high-throughput screening

S. Bates, J. Mcmahon, C. J. Henrich, 2007 .

Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α.

Kristina M. Cook, K. Gustafson, J. Mcmahon, 2015, Journal of the American Chemical Society.

Characterization of pomiferin triacetate as a novel mTOR and translation inhibitor.

K. Gustafson, Z. Dong, N. Colburn, 2014, Biochemical pharmacology.

Chronic ethanol exposure increases levels of protein kinase C δ and ε and protein kinase C-mediated phosphorylation in cultured neural cells

C. J. Henrich, R. Messing, P. Petersen, 1991 .

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

R. Chari, T. Sayers, A. Brooks, 2021, Cancer Research.

Identification of potential modulators of osteosarcoma metastasis by high‐throughput cellular screening of natural products

L. Jia, E. Goncharova, C. J. Henrich, 2020, Chemical biology & drug design.

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

G. Rao, G. Sittampalam, R. Lunsford, 2022, bioRxiv.

Swinhopeptolides A and B: Cyclic Depsipeptides from the Sponge Theonella swinhoei That Inhibit Ras/Raf Interaction.

C. Bewley, K. Gustafson, D. Morrison, 2020, Journal of natural products.

Identification of natural product modulators of Merkel cell carcinoma cell growth and survival

K. Gustafson, E. Goncharova, C. J. Henrich, 2021, Scientific Reports.

Natural Products Active in Aberrant c‐Kit Signaling

K. Gustafson, E. Goncharova, J. Mcmahon, 2007, Chemical biology & drug design.

A High-Throughput Cell-Based Assay to Identify Specific Inhibitors of Transcription Factor AP-1

N. Colburn, E. Goncharova, J. Mcmahon, 2007, Journal of biomolecular screening.

Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula.

N. Colburn, J. Mcmahon, C. J. Henrich, 2011, Journal of natural products.

Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii.

K. Gustafson, N. Colburn, J. Mcmahon, 2011, Bioorganic & medicinal chemistry letters.

A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits”

K. Gustafson, N. Colburn, J. Mcmahon, 2009, Molecular Cancer Therapeutics.

Transcription of early developmental isogenes in cardiac myocyte hypertrophy.

C. Long, P. Simpson, C. J. Henrich, 1989, Journal of molecular and cellular cardiology.

Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera.

K. Gustafson, J. Mcmahon, C. J. Henrich, 2012, Journal of natural products.

Steroidal Alkaloids from the Marine Sponge Corticium niger That Inhibit Growth of Human Colon Carcinoma Cells

K. Gustafson, D. Covell, J. Mcmahon, 2014, Journal of natural products.

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

Jason R. Evans, Y. Pommier, E. Goncharova, 2017, SLAS discovery : advancing life sciences R & D.

Tolypocladamides A-G: Cytotoxic Peptaibols from Tolypocladium inflatum.

D. Morrison, C. J. Henrich, A. Stephen, 2022, Journal of natural products.

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

N. Booth, T. Sayers, A. Brooks, 2011, Apoptosis.

Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

S. Marfil, R. Twyman, A. Tanuri, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Chronic ethanol exposure increases levels of protein kinase C delta and epsilon and protein kinase C-mediated phosphorylation in cultured neural cells.

C. J. Henrich, R. Messing, P. Petersen, 1991, The Journal of biological chemistry.

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities.

L. Staudt, K. Gustafson, C. J. Henrich, 2019, Journal of natural products.

Molecular weight dependence of hyaluronic acid produced during oncogenic transformation.

C. J. Henrich, S. Hawkes, 1989, Cancer biochemistry biophysics.

Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells.

Karlyne M. Reilly, K. Reilly, J. Mcmahon, 2014, Phytochemistry letters.

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities.

L. Staudt, K. Gustafson, C. J. Henrich, 2019, Journal of natural products.

Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways.

E. Goncharova, C. J. Henrich, J. Beutler, 2024, Journal of natural products.