V. Radha

发表

Direct Transcriptional Activation of Human Caspase-1 by Tumor Suppressor p53*

Sanjeev Gupta, V. Radha, Y. Furukawa, 2001, The Journal of Biological Chemistry.

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

V. Radha, G. Swarup, D. Balasubramanian, 2010, BMC Cell Biology.

pH and thermosensitive 5-fluorouracil loaded poly(NIPAM-co-AAc) nanogels for cancer therapy

Syeda Juveriya Fathima, V. Radha, F. Khanum, 2016 .

The guanine nucleotide exchange factor, C3G regulates differentiation and survival of human neuroblastoma cells

V. Radha, R. Gupta, T. Raman, 2008, Journal of neurochemistry.

Understanding the SARS-CoV-2 to Manage COVID-19

V. Radha, Somdatta Karak, 2020, Indian Journal of Cardiovascular Disease in Women WINCARS.

The tyrosine phosphatase TC48 interacts with and inactivates the oncogenic fusion protein BCR-Abl but not cellular Abl.

V. Radha, A. Mitra, K. Sasikumar, 2013, Biochimica et biophysica acta.

Two Splice Variants of a Tyrosine Phosphatase Differ in Substrate Specificity, DNA Binding, and Subcellular Location*

V. Radha, G. Swarup, S. Nambirajan, 1996, The Journal of Biological Chemistry.

Expression of a novel brain specific isoform of C3G is regulated during development

V. Radha, B. Parthasaradhi, I. Mariappan, 2020, Scientific Reports.

Nuclear Matrix: Methods of Preparation

V. Radha, G. Swarup, 2001 .

F-actin-binding domain of c-Abl regulates localized phosphorylation of C3G: role of C3G in c-Abl-mediated cell death

V. Radha, A. Mitra, Aninda Mitra, 2010, Oncogene.

RAPGEF1 (Rap guanine nucleotide exchange factor (GEF) 1)

V. Radha, A. Mitra, 2011 .

Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.

V. Radha, K. Dayma, A. Mitra, 2011, Bioscience reports.

A nuclear protein tyrosine phosphatase activates p53 and induces caspase‐1‐dependent apoptosis

Sanjeev Gupta, V. Radha, G. Swarup, 2002, FEBS letters.

CDC20siRNA and paclitaxel co-loaded nanometric liposomes of a nipecotic acid-derived cationic amphiphile inhibit xenografted neuroblastoma.

V. Radha, A. Chaudhuri, Sukanya Bhunia, 2017, Nanoscale.

PTP-S2, a nuclear tyrosine phosphatase, is phosphorylated and excluded from condensed chromosomes during mitosis

V. Radha, G. Swarup, S. Nambirajan, 2000, Journal of Biosciences.

C3G (RapGEF1), a regulator of actin dynamics promotes survival and myogenic differentiation of mouse mesenchymal cells.

V. Radha, S. Kaniyappan, K. Dayma, 2015, Biochimica et biophysica acta.

Induction of p53 dependent apoptosis upon overexpression of a nuclear protein tyrosine phosphatase

V. Radha, G. Swarup, C. Sudhakar, 1999, FEBS letters.

NLRC4 (NLR Family, CARD domain containing 4)

V. Radha, G. Swarup, Y. Kumar, 2011 .

Molecular cloning and expresion of a protein‐tyrosine phosphatase showing homology with transcription factors Fos and Jun

V. Radha, G. Swarup, V. Rema, 1991, FEBS letters.

SOME VARIATIONS OF MINUS DOMINATING FUNCTIONS OF CORONA OF A CYCLE WITH A COMPLETE GRAPH

V. Radha, M. Parvathi, 2018 .

Physical and Functional Interaction between Hck Tyrosine Kinase and Guanine Nucleotide Exchange Factor C3G Results in Apoptosis, Which Is Independent of C3G Catalytic Domain*

V. Radha, G. Swarup, C. Sudhakar, 2003, Journal of Biological Chemistry.

Induction of cytochrome c release and apoptosis by Hck-SH3 domain-mediated signalling requires caspase-3

V. Radha, G. Swarup, C. Sudhakar, 2002, Apoptosis.

TC-PTP Dephosphorylates the Guanine Nucleotide Exchange Factor C3G (RapGEF1) and Negatively Regulates Differentiation of Human Neuroblastoma Cells

V. Radha, Vijay R. Gupta, Srinivasan Kalayarasan, 2011, PloS one.

A Disease-associated Mutant of NLRC4 Shows Enhanced Interaction with SUG1 Leading to Constitutive FADD-dependent Caspase-8 Activation and Cell Death*

V. Radha, G. Swarup, Y. Kumar, 2016, The Journal of Biological Chemistry.

A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

V. Radha, G. Swarup, Vijay R. Gupta, 2007, Investigative ophthalmology & visual science.

Interaction with Sug 1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death

V. Radha, G. Swarup, Y. Kumar, 2010 .

BMC Molecular Biology BioMed Central Research article Regulation of p73 by Hck through kinase-dependent and

V. Radha, G. Swarup, P. Paliwal, 2007 .

Association of Lyn tyrosine kinase with the nuclear matrix and cell-cycle-dependent changes in matrix-associated tyrosine kinase activity.

V. Radha, G. Swarup, S. Nambirajan, 1996, European journal of biochemistry.

In vivo radioprotection by 5-aminosalicylic acid.

V. Radha, T. Mukherjee, S. Mantena, 2008, Mutation research.

M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells

V. Radha, G. Swarup, A. Kumari, 2013, Autophagy.

Binding of a protein-tyrosine phosphatase to DNA through its carboxy-terminal noncatalytic domain.

V. Radha, G. Swarup, S. Kamatkar, 1993, Biochemistry.

661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively

V. Radha, G. Swarup, Kapil Sirohi, 2017, Scientific Reports.

A nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-Myc protein level.

V. Radha, G. Swarup, P. Manogaran, 2001, Experimental cell research.

HSC70 as a sensor of low temperature: role in cold‐triggered autoinflammatory disorders

V. Radha, G. Swarup, Akhouri Kishore Raghawan, 2021, The FEBS journal.

Use of Dominant-Negative/Substrate Trapping PTP Mutations to Search for PTP Interactors/Substrates.

V. Radha, 2016, Methods in molecular biology.

C3G dynamically associates with nuclear speckles and regulates mRNA splicing

V. Radha, B. Muralikrishna, D. Shakyawar, 2017, bioRxiv.

C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation.

V. Radha, G. Swarup, N. Rangaraj, 2007, Experimental cell research.

Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death.

V. Radha, G. Swarup, Y. Kumar, 2010, The Biochemical journal.

HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4

V. Radha, G. Swarup, Akhouri Kishore Raghawan, 2019, Proceedings of the National Academy of Sciences.

Complex formation and reciprocal regulation between GSK3β and C3G.

V. Radha, S. Rawat, K. Dayma, 2021, Biochimica et biophysica acta. Molecular cell research.

A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin

V. Radha, G. Swarup, A. Kumari, 2015, PloS one.

E50K-OPTN-Induced Retinal Cell Death Involves the Rab GTPase-Activating Protein, TBC1D17 Mediated Block in Autophagy

V. Radha, G. Swarup, A. Kumari, 2014, PloS one.

Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis

V. Radha, G. Swarup, S. Thalappilly, 2006, The FEBS journal.

Role of p73 in Regulating Human Caspase-1 Gene Transcription Induced by Interferon-γ and Cisplatin*

Sanjeev Gupta, V. Radha, G. Swarup, 2005, Journal of Biological Chemistry.

The need to develop a framework for human-relevant research in India: Towards better disease models and drug discovery

V. Radha, Surat Parvatam, Sham Bharadwaj, 2020, Journal of biosciences.

C3G localizes to the mother centriole in a cenexin-dependent manner and regulates centrosome duplication and primary cilium length

V. Radha, S. C. Nayak, 2020, Journal of Cell Science.

C3G (RapGEF1) localizes to the mother centriole and regulates centriole division and primary cilia dynamics

V. Radha, S. C. Nayak, 2019, bioRxiv.

C3G shows regulated nucleocytoplasmic exchange and represses histone modifications associated with euchromatin

V. Radha, C. Varalakshmi, K. Dayma, 2017, Molecular biology of the cell.

TITLE : C 3 G dynamically associates with Nuclear speckles and regulates mRNA splicing RUNNING HEAD : C 3 G regulates splicing

V. Radha, B. Muralikrishna, D. Shakyawar, 2017 .

Cytoskeletal remodeling by C3G to induce neurite-like extensions and inhibit motility in highly invasive breast carcinoma cells.

V. Radha, K. Dayma, 2011, Biochimica et biophysica acta.

Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton

V. Radha, G. Swarup, A. Rajanna, 2004, BMC Cell Biology.

Reciprocal Negative Regulation between the Guanine Nucleotide Exchange Factor C3G and β-Catenin.

V. Radha, K. Dayma, K. Sasikumar, 2012, Genes & cancer.

C3G Regulates STAT3, ERK, Adhesion Signaling, and Is Essential for Differentiation of Embryonic Stem Cells

Divya Tej Sowpati, V. Radha, D. T. Sowpati, 2021, Stem Cell Reviews and Reports.

Development and characterization of a novel monoclonal antibody that recognizes an epitope in the central protein interaction domain of RapGEF1 (C3G)

V. Radha, Z. Begum, C. Varalakshmi, 2018, Molecular Biology Reports.

Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis

T. Kundu, Sanjeev Gupta, V. Radha, 2005, Oncogene.

Dynamic changes in nuclear localization of a DNA-binding protein tyrosine phosphatase TCPTP in response to DNA damage and replication arrest

V. Radha, N. Sree, Ramadhas Anesh, 2012, Cell Biology and Toxicology.

Subcellular localization of a protein-tyrosine phosphatase: evidence for association with chromatin.

V. Radha, G. Swarup, S. Nambirajan, 1994, Biochemical Journal.

Stabilization of a protein-tyrosine phosphatase mRNA upon mitogenic stimulation of T-lymphocytes.

V. Radha, G. Swarup, G. V. Rajendrakumar, 1993, Biochimica et biophysica acta.

Protein-tyrosine phosphatases as regulators of protein kinase activity

V. Radha, G. Swarup, 1992 .

Overexpression of a nuclear protein tyrosine phosphatase increases cell proliferation

V. Radha, G. Swarup, S. Nambirajan, 1997, FEBS letters.

NUCLEAR PROTEIN TYROSINE PHOSPHATASES AND CONTROL OF CELL PROLIFERATION

V. Radha, G. Swarup, 1997 .

The need to develop a framework for human-relevant research in India: Towards better disease models and drug discovery

V. Radha, Surat Parvatam, Sham Bharadwaj, 2020, Journal of Biosciences.

Development and characterization of a novel monoclonal antibody that recognizes an epitope in the central protein interaction domain of RapGEF1 (C3G)

V. Radha, Z. Begum, C. Varalakshmi, 2018, Molecular Biology Reports.

potential regulation of the inflammatory response KGF alters gene expression in human airway epithelia

C. Poets, M. Welsh, W. Bernhard, 2015 .

Human primary retinal cells as an in-vitro model for investigating defective signalling caused by OPTN mutants associated with glaucoma

V. Radha, G. Swarup, M. Naik, 2021, Neurochemistry International.

Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton

V. Radha, G. Swarup, A. Rajanna, 2004, BMC Cell Biology.

New horizons of microphysiological systems: India forging its path in human-relevant research

V. Radha, Kasturi Mahadik, Surat Parvatam, 2023, Biology open.

CDC20siRNA and paclitaxel co-loaded nanometric liposomes of a nipecotic acid-derived cationic amphiphile inhibit xenografted neuroblastoma.

V. Radha, A. Chaudhuri, Sukanya Bhunia, 2017, Nanoscale.

CLASSIFICATION OF BENIGN AND MALIGNANT PULMONARY NODULES IN LDCT IMAGES USING RADIOMIC FEATURES

V. Radha, S. Ziyad, Thavavel Vayyapuri, 2021 .

Development and tissue specific expression of RAPGEF1 (C3G) transcripts having exons encoding disordered segments with predicted regulatory function

V. Radha, Archana Verma, Abhishek Goel, 2024, bioRxiv.