F. Bartel

发表

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

A. Levine, Shih-Jen Hwang, L. Strong, 2004, Cell.

Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53

H. Taubert, A. Meye, M. Bache, 2001, International journal of cancer.

Significance of HDMX‐S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis

Steffen Hauptmann, Matthias Bache, S. Hauptmann, 2005, International journal of cancer.

Correction for Deco et al., Key role of coupling, delay, and noise in resting brain fluctuations

G. Atwal, A. Levine, S. Hauptmann, 2009, Proceedings of the National Academy of Sciences.

Amplification of the mdm2 gene, but not expression of splice variants of mdm2 mrna, is associated with prognosis in soft tissue sarcoma

H. Taubert, A. Meye, M. Bache, 2001, International journal of cancer.

Gains in chromosomes 7, 8q, 15q and 17q are characteristic changes in malignant but not in benign peripheral nerve sheath tumors from patients with Recklinghausen's disease.

H. Taubert, A. Meye, M. Bache, 2000, Cancer letters.

Cytogenetic characterization of six malignant peripheral nerve sheath tumors: comparison of karyotyping and comparative genomic hybridization.

H. Taubert, M. Bache, R. Hinze, 2001, Cancer genetics and cytogenetics.

Inverse Expression of Cystein-rich 61 (Cyr61/CCN1) and Connective Tissue Growth Factor (CTGF/CCN2) in Borderline Tumors and Carcinomas of the Ovary

S. Hauptmann, F. Bartel, E. Gradhand, 2012, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

The effects of knockdown of wild-type survivin, survivin-2B or survivin-Δ3 on the radiosensitization in a soft tissue sarcoma cells in vitro under different oxygen conditions

H. Taubert, K. Trott, M. Bache, 2007, Cancer Gene Therapy.

Knockdown of survivin expression by small interfering RNA reduces the clonogenic survival of human sarcoma cell lines independently of p53

H. Taubert, A. Meye, M. Bache, 2004, Cancer Gene Therapy.

Increased survivin transcript levels: An independent negative predictor of survival in soft tissue sarcoma patients

C. Kampf, E. Rieber, H. Taubert, 2001, International journal of cancer.

Clinical utility of the X‐chromosome array

M. Bellomo, R. Stevenson, M. Lyons, 2013, American Journal of Medical Genetics. Part A.

mdm2 mRNA Level is a Prognostic Factor in Soft Tissue Sarcoma

H. Taubert, A. Meye, M. Bache, 2000, Molecular medicine.

Alterations of cancer‐related genes in soft tissue sarcomas: Hypermethylation of RASSF1A is frequently detected in leiomyosarcoma and associated with poor prognosis in sarcoma

H. Taubert, F. Bartel, K. Bluemke, 2005, International journal of cancer.

Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma

S. Hauptmann, H. Taubert, A. Meye, 2007, Oncogene.

The p53 status in juvenile chronic arthritis and rheumatoid arthritis

H. Taubert, A. Meye, M. Bache, 2000, Clinical and experimental immunology.

Reduced expression of hMSH2 protein is correlated to poor survival for soft tissue sarcoma patients

H. Taubert, A. Meye, M. Bache, 2003, Cancer.

Isolation and enrichment of urologic tumor cells in blood samples by a semi-automated CD45 depletion autoMACS protocol.

M. Wirth, H. Taubert, A. Meye, 2002, International journal of oncology.

A MboII polymorphism in exon 11 of the human MDM2 gene occuring in normal blood donors and in soft tissue sarcoma patients: an indication for an increased cancer susceptibility?

H. Taubert, A. Meye, M. Bache, 2000, Mutation research.

Colony formation of soft tissue sarcoma cells is inhibited by lipid-mediated antisense oligodeoxynucleotides targeting the human mdm2 oncogene.

H. Taubert, A. Meye, M. Bache, 2000, Cancer letters.

Deletion of the immunoglobulin domain of IL1RAPL1 results in nonsyndromic X‐linked intellectual disability associated with behavioral problems and mild dysmorphism

C. Skinner, R. Stevenson, C. Schwartz, 2011, American journal of medical genetics. Part A.

Low detection rate of p53 antibodies in sera of soft tissue sarcoma patients.

H. Taubert, A. Meye, H. Schmidt, 2001, Cancer letters.

Alternative splicing of HDMX predicts p53 inactivation and bad prognosis

Kristiaan J. Lenos, A. Jochemsen, A. Cleton-Jansen, 2011 .

Thymomegaly, Microsplenia, and Defective Homeostatic Proliferation of Peripheral Lymphocytes in p51-Ets1 Isoform-Specific Null Mice

F. Bartel, Runzhao Li, R. Muise-Helmericks, 2007, Molecular and Cellular Biology.

Somatic/gonadal mosaicism in a syndromic form of ectrodactyly, including eye abnormalities, documented through array‐based comparative genomic hybridization

C. Skinner, C. Schwartz, F. Faucz, 2011, American journal of medical genetics. Part A.

[Both somatic and germline genetics of the TP53-pathway influence ovarian cancer incidence and survival].

S. Hauptmann, H. Taubert, F. Bartel, 2007, Verhandlungen der Deutschen Gesellschaft fur Pathologie.

Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines.

H. Taubert, F. Bartel, L. Harris, 2001, Oncology research.

BIOLOGY Correction for ‘ ‘ Dissection of the high rate constant for the binding of a ribotoxin to the ribosome

G. Atwal, A. Levine, S. Hauptmann, 2009 .

Alternative and aberrant splicing of MDM2 mRNA in human cancer.

H. Taubert, F. Bartel, L. Harris, 2002, Cancer cell.

47, XY, +der(Y),t(X;Y)(p21.1;p11.2): A unique case of XY sex reversal

F. Bartel, B. Dupont, K. Corning, 2011, American journal of medical genetics. Part A.

Disruption of MBD5 contributes to a spectrum of psychopathology and neurodevelopmental abnormalities

J. Gusella, C. Morton, M. Talkowski, 2014, Molecular Psychiatry.

Gains of 13q are correlated with a poor prognosis in liposarcoma

H. Taubert, M. Bache, H. Holzhausen, 2005, Modern Pathology.

MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides.

H. Taubert, P. Würl, F. Bartel, 2004, Molecular cancer research : MCR.

Small polydispersed circular DNA contains strains of mobile genetic elements and occurs more frequently in permanent cell lines of malignant tumors than in normal lymphocytes.

S. Hauptmann, H. Taubert, W. Schmitt, 2009, Oncology reports.

Both Germ Line and Somatic Genetics of the p53 Pathway Affect Ovarian Cancer Incidence and Survival

S. Hauptmann, C. Thomssen, F. Bartel, 2008, Clinical Cancer Research.

Analysis of central regulatory pathways in p53-deficient primary cultures of malignant fibrous histiocytoma exposed to ifosfamide.

H. Taubert, U. Brinck, T. Schlott, 2004, Anticancer research.

An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity.

C. Denkert, S. Hauptmann, J. Marine, 2010, Cancer research.

Stem cell-associated genes are extremely poor prognostic factors for soft-tissue sarcoma patients

S. Hauptmann, H. Taubert, A. Meye, 2007, Oncogene.

NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration

Schraga Schwartz, F. Bartel, C. Müller-Tidow, 2020, Oncogene.

Clinical utility of chromosomal microarray analysis in the diagnosis and management of monosomy 7 mosaicism

E. Fung, M. Lyons, M. Friez, 2014, Molecular Cytogenetics.

High bad and bcl-xL gene expression and combined bad, bcl-xL, bax and bcl-2 mRNA levels: molecular predictors for survival of stage 2 soft tissue sarcoma patients.

H. Taubert, A. Meye, M. Bache, 2002, Anticancer research.

Elevated expression of survivin-splice variants predicts a poor outcome for soft-tissue sarcomas patients

S. Hauptmann, H. Taubert, A. Meye, 2005, Oncogene.

HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity*

J. Richter, A. Jochemsen, J. Blaydes, 2010, The Journal of Biological Chemistry.

Gains of 12q are the most frequent genomic imbalances in adult fibrosarcoma and are correlated with a poor outcome

H. Taubert, M. Bache, R. Hinze, 2002, Genes, chromosomes & cancer.

Association of HDM2 Transcript Levels with Age of Onset and Prognosis in Soft Tissue Sarcomas

S. Hauptmann, H. Taubert, M. Bache, 2008, Molecular Cancer Research.

Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients

T. Stiewe, C. Thomssen, J. Buchmann, 2019, Oncotarget.

A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation.

Emil Alexov, Michael Tiemeyer, Kazuhiro Aoki, 2014, Human molecular genetics.

MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner.

A. Levine, K. Offit, T. Kirchhoff, 2006, Cancer research.

Radiosensitization, after a combined treatment of survivin siRNA and irradiation, is correlated with the activation of caspases 3 and 7 in a wt-p53 sarcoma cell line, but not in a mt-p53 sarcoma cell line.

H. Taubert, M. Bache, H. Schmidt, 2005, Oncology reports.

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

H. Taubert, A. Jochemsen, A. Cleton-Jansen, 2012, Cancer research.

Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene

G. Atwal, A. Levine, S. Hauptmann, 2009, Proceedings of the National Academy of Sciences.

Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5

Oleg Timofeev, Marco Mernberger, Eva J Kantelhardt, 2016, Proceedings of the National Academy of Sciences.

High concentration of soluble HLA-DR in the synovial fluid: generation and significance in "rheumatoid-like" inflammatory joint diseases.

F. Bartel, K. Schumacher, M. Witt, 2000, Cellular immunology.

Mouse models in the study of the Ets family of transcription factors

F. Bartel, D. Spyropoulos, T. Higuchi, 2000, Oncogene.

Germline genetics of the p53 pathway affect longevity in a gender specific manner.

M. Klintschar, F. Bartel, U. Immel, 2014, Current aging science.

X‐linked mental retardation with alacrima and achalasia—Triple A syndrome or a new syndrome?

C. Schwartz, F. Bartel, L. Basel‐Vanagaite, 2011, American journal of medical genetics. Part A.

TRIM25 has a dual function in the p53/Mdm2 circuit

S. Inoue, T. Henrich, J. Wittbrodt, 2015, Oncogene.

Elevated expression level of survivin protein in soft-tissue sarcomas is a strong independent predictor of survival.

Matthias Bache, H. Taubert, A. Meye, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Detection of disseminated tumor cells in peripheral blood of patients with breast cancer: correlation to nodal status and occurrence of metastases.

H. Taubert, A. Meye, H. Holzhausen, 2004, Gynecologic oncology.

Expression of Cathepsin B, D and L Protein in Juvenile Idiopathic Arthritis

H. Taubert, A. Meye, M. Bache, 2002, Autoimmunity.

17p13.3 microduplications are associated with split-hand/foot malformation and long-bone deficiency (SHFLD)

C. Schwartz, K. Boycott, D. Bulman, 2011, European Journal of Human Genetics.

Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma

H. Taubert, A. Meye, M. Bache, 2002, The Lancet.

Expression of alternatively and aberrantly spliced transcripts of the MDM2 mRNA is not tumor-specific.

H. Taubert, H. Schmidt, P. Würl, 2004, International journal of oncology.

Loss of Heterozygosity at 12q14-15 Often Occurs in Stage I Soft Tissue Sarcomas and Is Associated with MDM2 Amplification in Tumors at Various Stages

H. Taubert, M. Bache, H. Holzhausen, 2003, Modern Pathology.

Detection of circulating tumor cells from renal carcinoma patients: experiences of a two-center study.

M. Wirth, H. Taubert, A. Meye, 2005, Oncology reports.

Transfection with mdm2-antisense or wtp53 results in radiosensitization and an increased apoptosis of a soft tissue sarcoma cell line.

H. Taubert, A. Meye, M. Bache, 2001, Anticancer research.

Marker-assisted study of genetic background and gene-targeted locus modifiers in lymphopoietic phenotypes.

F. Bartel, D. Watson, M. Ogawa, 2003, Anticancer research.