K. Malcolm

发表

p53 integrates host defense and cell fate during bacterial pneumonia

P. Bushel, Leping Li, M. A. Resnick, 2013, The Journal of experimental medicine.

Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR

Scott H. Randell, S. Randell, K. Malcolm, 2011, PloS one.

Functional Genomics of Lung Disease

S. Redline, N. Friedman, A. Regev, 2004 .

Lipid Rafts Regulate Lipopolysaccharide-induced Activation of Cdc42 and Inflammatory Functions of the Human Neutrophil*

K. Malcolm, J. Nick, M. Fessler, 2004, Journal of Biological Chemistry.

Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis.

L. Saiman, K. Malcolm, J. Nick, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Pathogenic Nontuberculous Mycobacteria Resist and Inactivate Cathelicidin: Implication of a Novel Role for Polar Mycobacterial Lipids

E. Chan, K. Malcolm, S. Flores, 2015, PloS one.

Alternative pre-mRNA splicing of Toll-like receptor signaling components in peripheral blood mononuclear cells from patients with ARDS.

E. Abraham, T. Fingerlin, K. Malcolm, 2017, American journal of physiology. Lung cellular and molecular physiology.

Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis.

K. Malcolm, J. Nick, S. Young, 2004, Blood.

Urine lipoarabinomannan as a marker for low-risk of NTM infection in the CF airway.

K. Malcolm, J. Nick, P. De, 2020, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Effects of azithromycin in Pseudomonas aeruginosa burn wound infection.

K. Malcolm, J. Nick, S. Moskowitz, 2013, The Journal of surgical research.

Cell surface remodeling of Mycobacterium abscessus under cystic fibrosis airway growth conditions.

J. Parkhill, K. Malcolm, J. Nick, 2020, ACS infectious diseases.

Mycobacterium abscessus Displays Fitness for Fomite Transmission

E. Chan, K. Malcolm, J. Nick, 2017, Applied and Environmental Microbiology.

Enhanced In Vitro Formation and Antibiotic Resistance of Nonattached Pseudomonas aeruginosa Aggregates through Incorporation of Neutrophil Products

K. Malcolm, J. Nick, D. Bratton, 2014, Antimicrobial Agents and Chemotherapy.

A novel method for long term bone marrow culture and genetic modification of murine neutrophils via retroviral transduction.

G. Downey, K. Malcolm, Y. Refaeli, 2009, Journal of immunological methods.

Selective Suppression of Neutrophil Accumulation in Ongoing Pulmonary Inflammation by Systemic Inhibition of p38 Mitogen-Activated Protein Kinase1

K. Malcolm, J. Nick, S. Young, 2002, The Journal of Immunology.

Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

Brian E. Vestal, Kendra Walton, K. Malcolm, 2022, Cell.

Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease.

S. Holland, K. Malcolm, R. Nemenoff, 2015, The Journal of allergy and clinical immunology.

Immune deficiencies , infection , and systemic immune disorders Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease

S. Holland, K. Malcolm, R. Nemenoff, 2022 .

IL-17A and TNF-α Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro

K. Malcolm, Ping Wang, S. Guttentag, 2010, The Journal of Immunology.

Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta.

K. Malcolm, W. Schiemann, V. Fadok, 2002, The Journal of biological chemistry.

Lipopolysaccharide-induced c-Jun NH2-terminal Kinase Activation in Human Neutrophils

K. Malcolm, G. Worthen, P. Arndt, 2004, Journal of Biological Chemistry.

Independent activation of endogenous p21‐activated protein kinase‐3 (PAK3) and JNK by thrombin in CCL39 fibroblasts

J. Pouysségur, K. Malcolm, J. Chambard, 2000, Journal of cellular physiology.

Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.

S. Randell, K. Malcolm, J. Nick, 2008, American journal of respiratory cell and molecular biology.

Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF)-Mediated Signaling Contributes to Innate Immune Responses in the Lung during Escherichia coli Pneumonia1

S. Akira, Masahiro Yamamoto, K. Malcolm, 2007, The Journal of Immunology.

Defective apoptotic cell phagocytosis attenuates prostaglandin E2 and 15-hydroxyeicosatetraenoic acid in severe asthma alveolar macrophages.

S. Wenzel, K. Malcolm, V. Fadok, 2005, American journal of respiratory and critical care medicine.

Pneumonia coli Escherichia Responses in the Lung during Signaling Contributes to Innate Immune ( TRIF )-Mediated β Adaptor Inducing IFN-Toll / IL-1 Receptor Domain-Containing

S. Akira, Masahiro Yamamoto, K. Malcolm, 2007 .

Two auxin-responsive domains interact positively to induce expression of the early indoleacetic acid-inducible gene PS-IAA 4 / 5 ( auxin action / linker-scanning mutagenesis / enhancer / titration of transcription factors / cooperativity )

A. Theologis, K. Malcolm, N. Ballas, 2005 .

Neutrophils and Bacterial Coinfection: Aiding and Abetting.

K. Malcolm, P. Bratcher, 2018, American journal of respiratory cell and molecular biology.

Measuring Neutrophil Bactericidal Activity.

K. Malcolm, 2018, Methods in molecular biology.

Enhanced Pseudomonas aeruginosa Biofilm Development Mediated by Human Neutrophils

K. Malcolm, J. Nick, M. Fessler, 2005, Infection and Immunity.

Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils.

K. Malcolm, J. Nick, H. D. Cavanagh, 2011, Investigative ophthalmology & visual science.

A Genomic and Proteomic Analysis of Activation of the Human Neutrophil by Lipopolysaccharide and its Mediation by p 38 Mitogen-Activated Protein Kinase

K. Malcolm, M. Fessler, M. Duncan, 2002 .

This information is current as Mitogen-Activated Protein Kinase Inflammation by Systemic Inhibition of p38 Accumulation in Ongoing Pulmonary Selective Suppression of Neutrophil

K. Malcolm, J. Nick, S. Young, 2013 .

Culture independent markers of nontuberculous mycobacterial (NTM) lung infection and disease in the cystic fibrosis airway.

K. Malcolm, J. Nick, R. Davidson, 2022, Tuberculosis.

Blood mRNA biomarkers distinguish variable systemic and sputum inflammation at treatment initiation of inhaled antibiotics in cystic fibrosis: A prospective non-randomized trial

M. Strand, T. Fingerlin, K. Malcolm, 2022, PloS one.

Epoxyeicosatrienoic acids inhibit Ca2+ entry into platelets stimulated by thapsigargin and thrombin.

K. Malcolm, F. Fitzpatrick, 1992, The Journal of biological chemistry.

14, 15-cis-episulfide-eicosatrienoic acid, an 'epoxygenase' eicosanoid analog, inhibits ionophore- but not thrombin-induced platelet aggregation.

K. Malcolm, J. Maclouf, F. Fitzpatrick, 1991, Molecular pharmacology.

Specificity of Immunoglobulin Response to Nontuberculous Mycobacteria Infection in People with Cystic Fibrosis

K. Malcolm, J. Nick, S. Cáceres, 2022, Microbiology spectrum.

Lipopolysaccharide stimulation of the human neutrophil: an analysis of changes in gene transcription and protein expression by oligonucleotide microarrays and proteomics.

K. Malcolm, M. Fessler, M. Duncan, 2002, Chest.

Deficient Complement Opsonization Impairs Mycobacterium avium Killing by Neutrophils in Cystic Fibrosis

K. Malcolm, J. Nick, S. Cáceres, 2023, Microbiology spectrum.

Bacteria-Specific Neutrophil Dysfunction Associated with Interferon-Stimulated Gene Expression in the Acute Respiratory Distress Syndrome

I. Douglas, K. Malcolm, J. Nick, 2011, PloS one.

A Genomic and Proteomic Analysis of Activation of the Human Neutrophil by Lipopolysaccharide and Its Mediation by p38 Mitogen-activated Protein Kinase*

K. Malcolm, M. Fessler, M. Duncan, 2002, The Journal of Biological Chemistry.

Activation of rat liver phospholipase D by the small GTP-binding protein RhoA.

M. Symons, K. Malcolm, R. Qiu, 1994, The Journal of biological chemistry.

Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome

M. Strand, E. Abraham, K. Malcolm, 2016, PloS one.

Lipopolysaccharide Stimulates p38-dependent Induction of Antiviral Genes in Neutrophils Independently of Paracrine Factors*

K. Malcolm, G. Worthen, Kenneth C. Malcolm, 2003, The Journal of Biological Chemistry.

Microarray analysis of lipopolysaccharide-treated human neutrophils.

E. Manos, David A Jones, K. Malcolm, 2003, American journal of physiology. Lung cellular and molecular physiology.

Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1α and hypoxia-inducible transcription factor-2α.

K. Malcolm, Aftab Ahmad, Shama Ahmad, 2013, American journal of respiratory cell and molecular biology.

A Role for Protein Phosphatase-2A in p38 Mitogen-activated Protein Kinase-mediated Regulation of the c-Jun NH2-terminal Kinase Pathway in Human Neutrophils*

Jerry A Nick, K. Malcolm, J. Nick, 2002, The Journal of Biological Chemistry.

Cross-talk between ERK and p38 MAPK Mediates Selective Suppression of Pro-inflammatory Cytokines by Transforming Growth Factor-β*

K. Malcolm, W. Schiemann, V. Fadok, 2002, The Journal of Biological Chemistry.

Thromboxane A2 synthesis in human erythroleukemia cells.

K. Malcolm, D. Jones, F. Fitzpatrick, 1991, Biochemical and biophysical research communications.

Indirect actions of thapsigargin on human platelets: activation of eicosanoid biosynthesis and cellular signaling pathways.

K. Malcolm, F. Fitzpatrick, 1992, The Journal of pharmacology and experimental therapeutics.

Blood mRNA biomarkers for detection of treatment response in acute pulmonary exacerbations of cystic fibrosis

M. Strand, K. Malcolm, J. Nick, 2013, Thorax.

Mycobacterium abscessus Clearance by Neutrophils Is Independent of Autophagy

K. Malcolm, J. Nick, K. Pohl, 2020, Infection and Immunity.

Evidence for Rho-mediated Agonist Stimulation of Phospholipase D in Rat1 Fibroblasts

K. Malcolm, J. Exton, C. M. Elliott, 1996, The Journal of Biological Chemistry.

Dual role for RhoA in suppression and induction of cytokines in the human neutrophil.

K. Malcolm, J. Nick, M. Fessler, 2007, Blood.

Mycobacterium abscessus Morphotype Comparison in a Murine Model

K. Malcolm, J. Nick, K. Kidwell, 2015, PloS one.

Mycobacterium abscessus Induces a Limited Pattern of Neutrophil Activation That Promotes Pathogen Survival

P. Reynolds, E. Chan, K. Malcolm, 2013, PloS one.

Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms

L. Kremer, K. Malcolm, J. Nick, 2018, PloS one.

Divergent host innate immune response to the smooth-to-rough M. abscessus adaptation to chronic infection

K. Malcolm, J. Nick, K. Poch, 2023, bioRxiv.

Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus

K. Malcolm, J. Nick, M. Zimmerman, 2022, Science Translational Medicine.

Purinergic agonist and G protein stimulation of phospholipase D in rat liver plasma membranes. Independence from phospholipase C activation.

K. Malcolm, J. Exton, S. Trammell, 1995, Biochimica et biophysica acta.

human neutrophil Dual role for RhoA in suppression and induction of cytokines in the

K. Malcolm, J. Nick, M. Fessler, 2013 .

Whole Blood Gene Expression Profiling Predicts Severe Morbidity and Mortality in Cystic Fibrosis: A 5‐Year Follow‐Up Study

M. Strand, K. Malcolm, J. Nick, 2018, Annals of the American Thoracic Society.

Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy

K. Malcolm, J. Nick, M. Vasil, 2009, Journal of medical microbiology.

Enhanced phospholipase D activity and altered morphology in RhoA-overexpressing RAT1 fibroblasts.

K. Malcolm, J. Exton, C. Sable, 1996, Biochemical and biophysical research communications.

Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis

E. Pietras, C. McMahon, K. Malcolm, 2023, Leukemia.

Dectin-1-Independent Macrophage Phagocytosis of Mycobacterium abscessus

K. Malcolm, J. Nick, K. Hisert, 2023, International journal of molecular sciences.