V. Sebastián-Pérez

发表

Identification of new allosteric sites and modulators of AChE through computational and experimental tools

T. Blundell, Carlos Roca, C. Requena, 2018, Journal of enzyme inhibition and medicinal chemistry.

From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease.

I. Carvalho, E. Sakamoto-Hojo, Carlos Roca, 2017, European journal of medicinal chemistry.

Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents.

Víctor Sebastián-Pérez, Carmen Gil, Nuria E Campillo, 2017, European journal of medicinal chemistry.

Medicinal and Biological Chemistry (MBC) Library: An Efficient Source of New Hits

Jean-Louis Reymond, Mahendra Awale, Víctor Sebastián-Pérez, 2017, J. Chem. Inf. Model..

Imidazole Derivatives as Promising Agents for the Treatment of Chagas Disease

H. D. de Koning, V. Sebastián-Pérez, L. Maes, 2019, Antimicrobial Agents and Chemotherapy.

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

I. D. de Esch, R. Leurs, H. D. de Koning, 2019, International journal for parasitology. Drugs and drug resistance.

Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

T. Blundell, V. Sebastián-Pérez, Ana Martínez, 2020, Journal of enzyme inhibition and medicinal chemistry.

Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3

V. Sebastián-Pérez, C. Pérez, Ana Martínez, 2018, Journal of enzyme inhibition and medicinal chemistry.

A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis

T. Blundell, W. Jacobs, V. Sebastián-Pérez, 2021, bioRxiv.

Discovery of novel Schistosoma mansoni PDE4A inhibitors as potential agents against schistosomiasis.

R. Leurs, H. D. de Koning, V. Sebastián-Pérez, 2019, Future medicinal chemistry.

Chagas disease † 1 2 RUNNING TITLE : Imidazoles : antichagasic agents 3 4

V. Sebastián-Pérez, L. Maes, Cristina Fonseca-Berzal, 2019 .

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of Leishmania GSK-3

V. Sebastián-Pérez, C. Pérez, N. Campillo, 2022, Biomedicines.

QSARModelling to Identify LRRK 2 Inhibitors for Parkinson ’ sDisease

V. Sebastián-Pérez, N. Campillo, María JimenaMartínez, 2019 .

Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.

I. Carvalho, Carlos Roca, V. Sebastián-Pérez, 2018, European journal of medicinal chemistry.

Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation

V. Sebastián-Pérez, P. Dunman, A. Casiraghi, 2021, Antibiotics.

Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3

V. Sebastián-Pérez, Ana Martínez, N. Campillo, 2019, Journal of enzyme inhibition and medicinal chemistry.

New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth.

V. Sebastián-Pérez, Ana Martínez, N. Campillo, 2016, European journal of medicinal chemistry.

Benzodioxane‐Benzamides as Antibacterial Agents: Computational and SAR Studies to Evaluate the Influence of the 7‐Substitution in FtsZ Interaction

V. Sebastián-Pérez, M. Hrast, I. Zdovc, 2019, ChemMedChem.

Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity

V. Sebastián-Pérez, M. Hrast, I. Zdovc, 2020, Antibiotics.

Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy

H. D. de Koning, V. Sebastián-Pérez, Ana Martínez, 2018, Antimicrobial Agents and Chemotherapy.

Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket

V. Sebastián-Pérez, W. Margolin, M. Hrast, 2021, Antibiotics.

Cyclic nucleotide specific phosphodiesterases as potential drug targets 1 for anti-Leishmania therapy 2 3 RUNNING TITLE : PDEs : therapeutic targets for leishmaniasis

V. Sebastián-Pérez, N. Campillo, Ana, 2018 .

Hybridizing Feature Selection and Feature Learning Approaches in QSAR Modeling for Drug Discovery

Maria Vanina Martinez, Carlos Roca, V. Sebastián-Pérez, 2017, Scientific Reports.

QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

Maria Vanina Martinez, Gustavo E. Vazquez, Carlos Roca, 2019, Scientific Reports.

Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches

V. Sebastián-Pérez, N. Campillo, J. Lorenzo-Morales, 2020, Antimicrobial Agents and Chemotherapy.

QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

Maria Vanina Martinez, Fiorella Cravero, Ignacio Ponzoni, 2019, Scientific Reports.

Imidazole derivatives as promising agents for the treatment of Chagas disease † 1 2 RUNNING

V. Sebastián-Pérez, M. N. Soeiro, Cristina Fonseca-Berzal, 2018 .

QSAR Modelling to Identify LRRK2 Inhibitors for Parkinson’s Disease

Ignacio Ponzoni, María Jimena Martínez, Víctor Sebastián-Pérez, 2019, J. Integr. Bioinform..

QSAR Modelling for Drug Discovery: Predicting the Activity of LRRK2 Inhibitors for Parkinson's Disease Using Cheminformatics Approaches

Ignacio Ponzoni, María Jimena Martínez, Víctor Sebastián-Pérez, 2018, PACBB.