S. Rault

发表

Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor

T. Malliavin, É. Laine, C. Gonçalves, 2010, Proceedings of the National Academy of Sciences.

β-Strand Mimicry: Exploring Oligothienylpyridine Foldamers

Jana Sopkova-de Oliveira Santos, S. Rault, M. Jouanne, 2016 .

Consensus QSAR Related to Global or MOA Models: Application to Acute Toxicity for Fish

S. Rault, Sylvain Lozano, M. Halm-Lemeille, 2010, Molecular informatics.

Applicability of CATALYST in ecotoxicology, a new promising tool for 3D-QSAR: study of chlorophenols.

S. Rault, R. Bureau, F. Briens, 1999, Ecotoxicology and environmental safety.

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

Jana Sopkova-de Oliveira Santos, Karim Benchenane, H. Vaudry, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Synthesis, inhibition of NO production and antiproliferative activities of some indole derivatives

S. Rault, A. Caruso, M. Sinicropi, 2009, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles.

Aurélien Lesnard, S. Rault, T. Cresteil, 2014, Bioorganic & medicinal chemistry letters.

Interpretation of honeybees contact toxicity associated to acetylcholinesterase inhibitors.

S. Rault, F. Dulin, Sylvain Lozano, 2012, Ecotoxicology and environmental safety.

Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening.

Sylvain Rault, Maria A Miteva, Bruno O Villoutreix, 2011, Chemistry & biology.

Aromatic garlands, as new foldamers, to mimic protein secondary structure

Jana Sopkova-de Oliveira Santos, S. Rault, A. Voisin-Chiret, 2012 .

Synthesis of ortho-substituted cyanopyridines through lithio intermediate trapping

S. Rault, A. Bouillon, T. Cailly, 2005 .

Three‐dimensional model of the human urotensin‐II receptor: Docking of human urotensin‐II and nonpeptide antagonists in the binding site and comparison with an antagonist pharmacophore model

N. Colloc'h, S. Rault, R. Bureau, 2008, Proteins.

Rapid and soft formulation of folate-functionalized nanoparticles for the targeted delivery of tripentone in ovarian carcinoma.

S. Rault, L. Poulain, F. Carreiras, 2013, International journal of pharmaceutics.

Synthesis and Initial Results for MAO-B Inhibition by New N-Propargyl-3-pyrrol-1-ylindanamine Derivatives, Analogues of Rasagiline

Patrick Dallemagne, Sylvain Rault, Vincent Lisowski, 2003, Journal of enzyme inhibition and medicinal chemistry.

A New and Efficient Synthesis of 4-Arylimidazolidin-2-ones

S. Rault, P. Dallemagne, M. Robba, 1991 .

A New and Efficient Synthesis of 4-Arylimidazolidin-2-ones.

S. Rault, P. Dallemagne, M. Robba, 1991 .

Synthesis of new thienocyclopenta[3,2‐d]‐oxazole and thiazole derivatives

S. Rault, M. Boulouard, P. Dallemagne, 1993 .

Synthesis of 7-Amino-4,5,6,7-tetrahydrothieno[3,4-c]pyrid-4-ones

S. Rault, P. Dallemagne, Lan Pham Khanh, 1997 .

Synthesis and evaluation of the CNS activity of new 4-alkoxyphenylimidazolidin-2-ones.

S. Rault, M. Boulouard, O. Renault, 1998, Chemical & pharmaceutical bulletin.

Synthesis and preliminary behavioural evaluation in mice of new 3‐aryl‐3‐pyrrol‐1‐ylpropanamides, analogues of FGIN‐1–27 and FGIN‐1–43

S. Rault, M. Boulouard, C. Jarry, 2001, The Journal of pharmacy and pharmacology.

Comparative molecular field analysis of CCK-B antagonists

S. Rault, R. Bureau, M. Robba, 1994 .

Comparative molecular field analysis of CCK-A antagonists using field fit as alignment technique

S. Rault, R. Bureau, M. Robba, 1993 .

Synthesis and characterization of a iodine-125-labeled pyrrolo[1,2-a]thieno[3,2-e]pyrazine and evaluation as a potential 5-HT4R SPECT tracer.

Y. Charnay, S. Rault, P. Millet, 2010, European journal of medicinal chemistry.

Small-Animal Single-Photon Emission Computed Tomographic Imaging of the Brain Serotoninergic Systems in Wild-Type and Mdrla Knockout Rats

N. Ginovart, Y. Charnay, S. Rault, 2014, Molecular imaging.

(6-bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (carbhydraz) acts as a GPER agonist in breast cancer cells.

C. Rosano, S. Rault, M. Maggiolini, 2015, Current topics in medicinal chemistry.

The Maximum Common Substructure as a Molecular Depiction in a Supervised Classification Context: Experiments in Quantitative Structure/Biodegradability Relationships.

Ronan Bureau, Sylvain Rault, Bruno Crémilleux, 2010 .

The effects of DHEA, 3β-hydroxy-5α-androstane-6,17-dione, and 7-amino-DHEA analogues on short term and long term memory in the mouse

S. Rault, M. Boulouard, L. Kihel, 2009, Steroids.

First synthesis of 7alpha- and 7beta-amino-DHEA, dehydroepiandrosterone (DHEA) analogues and preliminary evaluation of their cytotoxicity on Leydig cells and TM4 Sertoli cells.

S. Rault, S. Carreau, C. Travert, 2007, Bioorganic & medicinal chemistry.

Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.

H. Vaudry, S. Rault, Magalie Paillet-Loilier, 2005, Bioorganic & medicinal chemistry letters.

Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines.

P Delagrange, M. Hamon, B. Guardiola-Lemaitre, 1996, Journal of medicinal chemistry.

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

B. Pfeiffer, S. Rault, F. Lezoualc’h, 2009, Bioorganic & medicinal chemistry.

Efficient synthesis of N1- or N3-substituted thieno[2,3-d]imidazol-2-ones

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1999 .

Thiaisatoic anhydrides: Efficient synthesis under microwave heating conditions and study of their reactivity

S. Rault, F. Fabis, M. Robba, 1998 .

[11C]S21007, a putative partial agonist for 5-HT3 receptors PET studies. Rat and primate in vivo biological evaluation.

J. Baron, L. Barré, M. Petit-Taboué, 1997, Life sciences.

First synthesis of 5,6‐dihydro‐4H‐furo[3,2‐f]pyrrolo‐ [1,2‐a][1,4]diazepines

S. Rault, J. Lancelot, Xiao Feng, 1998 .

2-Oxo-2-(phen-2-ylpyrrol-2-yl)acetamides as potential anxiolytic agents: Synthesis and affinity at the central benzodiazepine receptor

S. Rault, M. Boulouard, M. Daoust, 1998 .

A CONVENIENT SYNTHESIS OF NEW HALOTHIENYL β-AMINOACIDS AS VERSATILE BUILDING BLOCKS

S. Rault, O. Renault, P. Dallemagne, 1997 .

First synthesis of 4H‐furo[3,2‐f]pyrrolo[1,2‐a][1,4]diazepines

S. Rault, J. Lancelot, Xiao Feng, 1996 .

Pharmacological studies and synthesis of morpholino alkyl derivatives.

S. Rault, A. Capasso, C. Saturnino, 2002, Chemical & pharmaceutical bulletin.

Suzuki-type cross-coupling reaction of 3-iodoindazoles with aryl boronic acids: A general and flexible route to 3-arylindazoles

S. Rault, P. Dallemagne, P. Bovy, 1999 .

Heck cross-coupling reaction of 3-iodoindazoles with methyl acrylate: a mild and flexible strategy to design 2-aza tryptamines

S. Rault, V. Collot, Didier Varlet, 2000 .

Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors.

L. Meijer, S. Rault, R. Bureau, 2009, European journal of medicinal chemistry.

Direct synthesis of new arylanthranilic acids via a Suzuki cross-coupling reaction from iodoisatins

S. Rault, V. Lisowski, Anne-Laure Gérard, 2005 .

Hydrogenative desulphurization of thienopyrrolizinones: an easy and selective access to (Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity.

S. Rault, Rémi Legay, T. Cresteil, 2010, European journal of medicinal chemistry.

Synthesis of New Dipyrrolo‐ and Furopyrrolopyrazinones Related to Tripentones and Their Biological Evaluation as Potential Kinases (CDKs1—5, GSK‐3) Inhibitors.

Jana Sopkova-de Oliveira Santos, L. Meijer, S. Rault, 2009 .

First synthesis of arylpyrrolo- and pyrazolopyrrolizinones as useful agents with potential biological interest

S. Rault, V. Lisowski, P. Dallemagne, 2004 .

Design, synthesis, and evaluation of novel thienopyrrolizinones as antitubulin agents.

P. Renard, S. Rault, V. Lisowski, 2004, Journal of medicinal chemistry.

Design, synthesis and antiproliferative activity of tripentones: a new series of antitubulin agents.

P. Renard, S. Rault, V. Lisowski, 2001, Bioorganic & medicinal chemistry letters.

9-Ethyl-1,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole and 6-bromo-9-ethyl-1,4-dimethyl-9H-carbazole.

S. Rault, A. Caruso, J. Lancelot, 2008, Acta crystallographica. Section C, Crystal structure communications.

Quinoline derivatives: potential antiparasitic and antiviral agents.

S. Rault, J. Sopková-de Oliveira Santos, P. Vanelle, 2007, Acta crystallographica. Section C, Crystal structure communications.

7-Methoxy-1H-indazole, a new inhibitor of neuronal nitric oxide synthase.

S. Rault, J. Sopková-de Oliveira Santos, V. Collot, 2002, Acta crystallographica. Section C, Crystal structure communications.

7-Nitro-1H-indazole, an inhibitor of nitric oxide synthase.

S. Rault, J. Sopková-de Oliveira Santos, V. Collot, 2000, Acta crystallographica. Section C, Crystal structure communications.

3D‐QSAR and Docking Studies of Selective GSK‐3β Inhibitors. Comparison with a Thieno[2,3‐b]pyrrolizinone Derivative, a New Potential Lead for GSK‐3β Ligands.

Jana Sopkova-de Oliveira Santos, S. Rault, V. Lisowski, 2005 .

Comparative Molecular Field Analysis of Chlorophenols. application in Ecotoxicology

S. Rault, R. Bureau, F. Briens, 1994 .

First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump.

Aurélien Lesnard, S. Rault, T. Cresteil, 2014, Journal of medicinal chemistry.

Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives.

Aurélien Lesnard, S. Rault, T. Cresteil, 2015, European journal of medicinal chemistry.

Sequential one pot double C H heteroarylation of thiophene using bromopyridines to synthesize unsymmetrical 2,5-bipyridylthiophenes

Jana Sopkova-de Oliveira Santos, S. Rault, M. Jouanne, 2017 .

Synthesis and Structure-Affinity Relationships of Selective High- Affinity 5-HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers

Y. Charnay, D. Caignard, S. Rault, 2012 .

Efficient and Simple Synthesis of 6-Aryl-1,4-dimethyl-9H-carbazoles

S. Rault, A. Garofalo, A. Caruso, 2008, Molecules.

A new and efficient synthesis of 2-azatryptophans

S. Rault, V. Collot, S. Stiebing, 2006 .

Sonogashira cross-coupling reaction of 3-iodoindazoles with various terminal alkynes: a mild and flexible strategy to design 2-aza tryptamines

S. Rault, C. Alayrac, B. Witulski, 2002 .

A New Synthetic Route to Original Sulfonamide Derivatives in 2-Trichloromethylquinazoline Series: A Structure-Activity Relationship Study of Antiplasmodial Activity

S. Rault, N. Azas, P. Vanelle, 2012, Molecules.

Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.

E. Mackenzie, S. Rault, F. Dauphin, 2001, Bioorganic & medicinal chemistry letters.

Synthesis of a novel class of non-peptide NK-2 receptor ligand, derived from 1-phenyl-3-pyrrol-1-ylindan-2-carboxamides.

S. Rault, J. Leger, C. Jarry, 2002, Bioorganic & medicinal chemistry.

Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode.

L. weiswald, S. Rault, L. Carlier, 2018, European journal of medicinal chemistry.

Two-step synthesis of substituted 3-aminoindazoles from 2-bromobenzonitriles.

S. Rault, T. Cailly, F. Fabis, 2010, The Journal of organic chemistry.

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines.

S. Rault, N. Azas, M. Gasquet, 2008, Bioorganic & medicinal chemistry letters.

FRIEDEL-CRAFTS ACYLATION WITH MALONIC ACIDS IN POLYPHOSPHORIC ACID

S. Rault, O. Renault, P. Dallemagne, 1999 .

New arylhexahydropyrimidinediones: Synthesis, benzodiazepine receptor affinity and anticonvulsant activity

S. Rault, M. Boulouard, P. Dallemagne, 1996 .

Synthesis of [11C]‐S21007 a novel 5HT3 partial agonist as a potential tracer for PET studies

L. Barré, S. Rault, S. Guillouet, 1996 .

First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies.

S. Rault, L. Ligat, F. Lopez, 2015, Journal of medicinal chemistry.

Pyrrolothieno[1,4]diazepines Part 1 : Synthesis and Study of the Reaction Pathway

S. Rault, M. Boulouard, P. Dallemagne, 1995 .

Total deprotection of N,N′-bis(tert-butoxycarbonyl)guanidines using SnCl4

Sylvain Rault, S. Rault, Hugues Miel, 1997 .

Design and synthesis of a new indazole library: direct conversion of N-methoxy-N-methylamides (Weinreb amides) to 3-keto and 3-formylindazoles

S. Rault, Rémi Legay, V. Collot, 2007 .

A novel synthesis of methyl cis-(3-thienyl)glycidate with 2-aminothiophenol and the synthesis of [1,5]benzothiazepine derivatives

S. Rault, C. Saturnino, J. Lancelot, 1992 .

[1]Benzothienopyrimidines. II. Study of the electrophilic substitutions of [1]benzothieno[3,2-d]pyrimidine and [1]benzothieno[3,2-d]pyrimidin-4-(3H)one

S. Rault, H. El-Kashef, M. Robba, 1980 .

Synthesis and pharmacological activities of some 2,3,4,5-tetrahydro[1,5]benzo[f]thiazepines.

S. Rault, C. Saturnino, G. de Martino, 1997, Farmaco.

Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.

Y. Charnay, D. Caignard, S. Rault, 2012, Journal of medicinal chemistry.

Straightforward access to ethyl 3-aminofuropyridine-2-carboxylates from 1-chloro-2-cyano-or 1 -hydroxy -2 -cyano -substituted pyridines

S. Rault, T. Cailly, F. Fabis, 2007 .

Efficient synthesis of halohydroxypyridines by hydroxydeboronation

S. Rault, A. Voisin, A. Bouillon, 2005 .

Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.

S. Rault, N. Azas, M. Gasquet, 2009, Bioorganic & medicinal chemistry.

General method for the synthesis of substituted phenanthridin-6(5H)-ones using a KOH-mediated anionic ring closure as the key step

S. Rault, Rémi Legay, T. Cailly, 2010 .

Synthesis of novel halopyridinylboronic acids and esters. Part 2: 2,4, or 5-Halopyridin-3-yl-boronic acids and esters

S. Rault, A. Bouillon, J. Lancelot, 2002 .

Synthesis of novel halo-oxybispyridines, new building blocks in cholinergic medicinal chemistry

Aurélien Lesnard, S. Rault, A. Voisin, 2006 .

Straightforward Access to Ethyl 3‐Aminofuropyridine‐2‐carboxylates from 1‐Chloro‐2‐cyano‐ or 1‐Hydroxy‐2‐cyano‐Substituted Pyridines.

S. Rault, T. Cailly, F. Fabis, 2008 .

Synthesis of dihalo bi- and terpyridines by regioselective Suzuki–Miyaura cross-coupling reactions

Jana Sopkova-de Oliveira Santos, Sylvain Rault, Anne Sophie Voisin-Chiret, 2009 .

Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization.

S. Rault, B. Rizzuti, C. Saturnino, 2019, European journal of medicinal chemistry.

Synthesis of novel pyrazolopyrrolopyrazines, potential analogs of sildenafil

S. Rault, P. Dallemagne, J. Lancelot, 2001 .

Nanocarriers for the targeted treatment of ovarian cancers.

Sylvain Rault, S. Lheureux, S. Rault, 2013, Biomaterials.

One-pot synthesis of new aza- and diaza-aminophenanthrenes

Jana Sopkova-de Oliveira Santos, S. Rault, P. Dallemagne, 2011 .

Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents.

S. Rault, V. Lisowski, P. Dallemagne, 2006, Bioorganic & medicinal chemistry.

Four Partners, Three‐Step, One‐Pot Reaction for a Library of New 2‐Alkyl(dialkyl)aminoquinazolin‐4(3H)‐ones

Aurélien Lesnard, S. Rault, Rémi Legay, 2014 .

Cyclisation de l'acide amino-3 (thienyl-3)-3 propionique en aminocyclopentathiophenes

S. Rault, M. Robba, K. Hassan, 1986 .

Efficient Room‐Temperature One‐Pot Synthesis of 2‐Amino‐3‐alkyl(3‐aryl)quinazolin‐4(3H)‐ones

S. Rault, F. Fabis, C. Fossey, 2011 .

Synthesis of new 8-arylisoquinoline derivatives by application of palladium-catalyzed Suzuki cross-coupling reactions

S. Rault, F. Fabis, D. Cortes, 2005 .

First combined selective N- and C-arylations with boronic acids: application to the synthesis of 1,3-diarylindazoles

S. Rault, P. Bovy, V. Collot, 2000 .

Sonogashira cross-coupling reaction in 4-chloro-2-trichloromethylquinazoline series is possible despite a side dimerization reaction

S. Rault, Roselyne Rosas, P. Vanelle, 2013 .

Pyrido [2, 3-h] pyrrolo [1, 2-a] quinoxalines

S. Rault, J. Lancelot, M. Robba, 1983 .

An intermolecular dative B←N bond in 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole

S. Rault, A. Bouillon, J. Sopková-de Oliveira Santos, 2009, Acta crystallographica. Section E, Structure reports online.

Synthesis of 5-arylthiazoles. Comparative study between Suzuki cross-coupling reaction and direct arylation

S. Rault, A. Bouillon, J. Lancelot, 2009 .

Synthesis of New Ethyl 3-Amino-4-arylfuran-2-carboxylates

S. Rault, V. Lisowski, Xiao Feng, 2010 .

Synthesis and biological evaluation of five-membered heterocycles fused to cyclopenta[c]thiophene as new antitumor agents.

S. Rault, R. Bureau, P. Dallemagne, 2003, Bioorganic & medicinal chemistry.

Synthesis of phenylpyrrolylpyrroles. Part II

S. Rault, M. Robba, H. Dumoulin, 1996 .

4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.

S. Rault, M. Boulouard, P. Schumann-Bard, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of New 2‐(Aminomethyl)‐4‐phenylpyrrolo[1,2‐a]‐quinoxalines and their Preliminary In‐vivo Central Dopamine Antagonist Activity Evaluation in Mice

S. Rault, M. Boulouard, V. Lisowski, 2000, The Journal of pharmacy and pharmacology.

Synthesis of new pyrrolo(1,2-a)quinoxalines: potential non-peptide glucagon receptor antagonists

P. Renard, B. Pfeiffer, S. Rault, 1998 .

Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.

P Delagrange, M. Hamon, P. Renard, 1997, Journal of medicinal chemistry.

New aromatase inhibitors. Synthesis and biological activity of aryl-substituted pyrrolizine and indolizine derivatives.

J Guillon, S. Rault, S. Moslemi, 2000, Bioorganic & medicinal chemistry.

Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases.

J. Boucher, S. Rault, P. Schumann-Bard, 2003, Nitric oxide : biology and chemistry.

A convenient synthesis of dihydro- and tetrahydro-1,3-thiazine derivatives from β-aryl-β-amino acids

S. Rault, P. Dallemagne, Nicolas Leflemme, 2004 .

Novel Rearrangement of Pyrrolo[2,1-c][1,4]benzodiazepines into Pyrrolo[2,1-b]quinazolinones, Analogous of Alkaloid, Vasicinone

S. Rault, P. Ochsenbein, F. Fabis, 1999 .

Synthesis of new pyrrolo[2,1-b]quinazolinones by original rearrangement of pyrrolo[2,1-c][1,4]benzodiazepines

S. Rault, P. Ochsenbein, F. Fabis, 1998 .

Recent progress in the synthesis of five-membered heterocycle boronic acids and esters

S. Rault, A. Bouillon, N. Primas, 2010 .

Efficient synthesis of 6H-pyrido [3,2-b] carbazole derivatives from 3-amino-1,4-dimethyl carbazole

S. Rault, J. Lancelot, M. Robba, 1987 .

Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.

Jana Sopkova-de Oliveira Santos, S. Rault, F. Dauphin, 2005, European journal of medicinal chemistry.

An expedient synthesis of 6-arylpiperidine-2,4-diones by chain-extension of β-aryl-β-aminoacids

S. Rault, P. Dallemagne, Nicolas Leflemme, 2001 .

Synthesis and Anti-HSV-1 Activity of New 3-Amino-3-Arylpropionic Acid Esters

S. Rault, J. Boustie, P. Dallemagne, 1996 .

FIRST SYNTHESIS OF 4-AMINO-4,5-DIHYDRO-1-PHENYLCYCLOPENTA[ b]PYRROL-6(1H)-ONES

S. Rault, P. Dallemagne, F. Fabis, 1994 .

Effective cerebral antihypoxic activity of new aminocyclopentanones

S. Rault, P. Dallemagne, M. Robba, 1992 .

One-Pot Cyclization of Alkoxy-3-aminoindan-1-ones.

S. Rault, P. Dallemagne, M. Robba, 1991 .

Cyclisation of 3-Amino-3-[thienyl-3]-propionic Acid to Aminocyclopentathiophenes.

S. Rault, P. Dallemagne, M. Robba, 1986 .

Synthesis of [1]benzothieno[2,3‐e]pyrrolo[1,2a]pyrazines and related compounds

S. Rault, J. Lancelot, H. El-Kashef, 1986 .

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.

S. Rault, N. Azas, M. Laget, 2011, Bioorganic & medicinal chemistry letters.

Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.

S. Rault, N. Azas, P. Garrigue, 2011, European journal of medicinal chemistry.

Original one-pot microwave-promoted Hunsdiecker–Suzuki strategy: straightforward access to trans-1,2-diarylethenes from cinnamic acids

S. Rault, J. Lancelot, L. Kihel, 2007 .

Selective ortho-bromination of substituted benzaldoximes using Pd-catalyzed C-H activation: application to the synthesis of substituted 2-bromobenzaldehydes.

S. Rault, T. Cailly, F. Fabis, 2011, The Journal of organic chemistry.

A convenient microwave-assisted 5-amination of flavones

S. Rault, F. Fabis, F. Lefoulon, 2008 .

First synthesis of methyl 3-amino-4-(het)aryl-1H-pyrrole-2-carboxylates as useful scaffolds in medicinal chemistry

S. Rault, V. Lisowski, P. Dallemagne, 2004 .

Synthesis of novel pyrazolopyrrolizinones as prospective anticancer agents

Jana Sopkova-de Oliveira Santos, S. Rault, P. Dallemagne, 2006 .

Efficient and simple synthesis of 3-aryl-1H-pyrazoles

S. Rault, A. Bouillon, C. Mahatsekake, 2006 .

N‐substituted Piperazinopyridylsteroid Derivatives as Abiraterone Analogues Inhibit Growth and Induce Pro‐apoptosis in Human Hormone‐independent Prostate Cancer Cell Lines

M. Sgobba, S. Rault, S. Haider, 2013, Chemical biology & drug design.

Synthesis of novel halopyridinylboronic acids and esters. Part 4: Halopyridin-2-yl-boronic acids and esters are stable, crystalline partners for classical Suzuki cross-coupling☆

Jana Sopkova-de Oliveira Santos, S. Rault, A. Bouillon, 2003 .

Synthesis of New 8-Arylisoquinoline Derivatives by Application of Palladium-Catalyzed Suzuki Cross-Coupling Reactions.

S. Rault, F. Fabis, D. Cortes, 2005 .

Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines.

B. Cacciari, S. Rault, L. Kèlland, 1999, Journal of medicinal chemistry.

1,2,3,4,5,6‐Hexahydrobenzo[h][1,6]naphthyridin‐5‐ones: 5‐HT7 Receptor Affinity

S. Rault, F. Dauphin, Alain-Claude Gillard, 2000 .

Simultaneous tritium labelling of two potent 5-HT4 ligands.

L. Barré, S. Rault, S. Lemaître, 2010, European journal of medicinal chemistry.

Synthesis of some pyrimido[4′,5′:4,5]thieno[2,3-b]quinolines and related heterocycles

S. Rault, A. El-Dean, H. El-Kashef, 1996 .

Cyclopropyl‐tryptamine Analogues: Synthesis and Biological Evaluation as 5‐HT6 Receptor Ligands

S. Rault, Stéphane Gérard, J. Sapi, 2013, ChemMedChem.

A rapid and versatile synthesis of novel pyrimido[5,4-b]carbazoles

Aurélien Lesnard, S. Rault, Rémi Legay, 2009 .

Sequential Sonogashira and Suzuki Cross-Coupling Reactions in the Indole and Indazole Series

S. Rault, C. Alayrac, B. Witulski, 2005 .

New practical access to 2-azatryptophans and dehydro derivatives via the Wittig-Horner reaction

Jana Sopkova-de Oliveira Santos, S. Rault, J. Lohier, 2007 .

First Combined Selective N- and C-Arylations with Boronic Acids: Application to the Synthesis of 1,3-Diarylindazoles.

S. Rault, P. Bovy, V. Collot, 2001 .

Synthesis, Pharmacological Study and Modeling of 7-Methoxyindazole and Related Substituted Indazoles as Neuronal Nitric Oxide Synthase Inhibitors

Sylvain Rault, Nathalie Colloc'h, Pascale Schumann-Bard, 2003, Journal of enzyme inhibition and medicinal chemistry.

A new boronic-acid based strategy to synthesize 4(5)-(het)aryl-1H-imidazoles

Jana Sopkova-de Oliveira Santos, S. Rault, A. Bouillon, 2008 .

Intramolecular cyclisation of β-aryl-β-amino acids in the design of novel heterocyclic systems with therapeutic interest: an unfailing source of diversity.

S. Rault, P. Dallemagne, C. Rochais, 2010, Current medicinal chemistry.

Tripentones: a promising series of potent anti-cancer agents.

S. Rault, P. Dallemagne, C. Rochais, 2009, Anti-cancer agents in medicinal chemistry.

Synthesis of new phenylpyrrolylpyrroles

S. Rault, M. Robba, H. Dumoulin, 1995 .

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.

S. Rault, N. Azas, M. Laget, 2015, Bioorganic & medicinal chemistry.

Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series.

S. Rault, N. Azas, M. Laget, 2015, European journal of medicinal chemistry.

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents.

Aurélien Lesnard, S. Rault, N. Azas, 2014, European journal of medicinal chemistry.

Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series

S. Rault, P. Vanelle, P. Rathelot, 2006 .

Highly efficient microwave assisted α-trichlorination reaction of α-methylated nitrogen containing heterocycles

S. Rault, P. Vanelle, P. Rathelot, 2006 .

Pyrrolothienopyrimidines. Part 2. Synthesis of 4-Aminopyrrolo[1,2-a]thieno[3,2-e](and[2,3-e]) Pyrimidines.

S. Rault, J. Lancelot, M. Robba, 1986 .

PYRIDO(2,3-H)PYRROLO(1,2-A)QUINOXALINES

S. Rault, J. Lancelot, M. Robba, 1984 .

Synthesis of new dehydro 2-azatryptophans and derivatives via heck cross-coupling reactions of 3- iodoindazoles with methyl 2-(acetylamino)acrylate

S. Rault, V. Collot, S. Stiebing, 2006 .

A new, direct, and efficient synthesis of benzonaphthyridin-5-ones

S. Rault, T. Cailly, F. Fabis, 2006 .

An expedient one-pot synthesis of novel 10-substituted 9-aminophenanthrenes

S. Rault, P. Dallemagne, C. Rochais, 2009 .

An expedient route to aromatic pyrrolo[2,1-c][1,4]benzodiazepines and a study of their reactivity

Jana Sopkova-de Oliveira Santos, S. Rault, F. Fabis, 2001 .

Synthesis of new 6-(4-chlorophenyl)perhydro-1,3-diazepine-2,4-diones via ureidobutyric acids

S. Rault, M. Boulouard, P. Sonnet, 1998 .

Design, synthesis and antiproliferative activity of tripentones: a new series of antitubulin agents.

P. Renard, S. Rault, V. Lisowski, 2001, Bioorganic & medicinal chemistry letters.

One-pot synthesis of novel poly-substituted phenanthrenes

Jana Sopkova-de Oliveira Santos, S. Rault, P. Dallemagne, 2010 .

3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression.

S. Catalano, S. Andò, Aurélien Lesnard, 2016, European journal of medicinal chemistry.

First and mild synthesis of fluorene-9-malonic acid and some substituted derivatives via the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids

Jana Sopkova-de Oliveira Santos, S. Rault, Rémi Legay, 2011 .

A convenient route to 6-aminocyclopenta[c]thiophen-4-one derivatives

S. Rault, M. Boulouard, P. Dallemagne, 1987 .

General Method for the Synthesis of Substituted Phenanthridin‐6(5H)‐ones Using a KOH‐Mediated Anionic Ring Closure as the Key Step.

S. Rault, Rémi Legay, T. Cailly, 2010 .

The synthesis of three new heterocycles: the pyrido[4,3 or 3,4 or 2,3-c]-1,5-naphthyridines

S. Rault, Rémi Legay, H. Oulyadi, 2007 .

Synthesis of 5‐Arylthiazoles. Comparative Study Between Suzuki Cross‐Coupling Reaction and Direct Arylation.

S. Rault, A. Bouillon, J. Lancelot, 2009 .

Synthesis of 2-TIPS-oxazol-5-ylboronic acid pinacol ester: efficient route to 5-(het)aryloxazoles via Suzuki cross-coupling reaction

S. Rault, A. Bouillon, J. Lancelot, 2009 .

Synthesis of novel triazolopyridylboronic acids and esters. Study of potential application to Suzuki-type reactions

S. Rault, A. Bouillon, J. Lancelot, 2004 .

A NEW EFFICIENT SYNTHESIS OF 3-AMINO-1-PHENYLPYRROLE

S. Rault, P. Dallemagne, F. Fabis, 1995 .

Applicability of CoMFA in ecotoxicology: a critical study on chlorophenols.

S. Rault, R. Bureau, F. Briens, 1995, Ecotoxicology and environmental safety.

New Synthesis and Preparative Resolution of Nornomifensine, a Useful Precursor for Positron Emission Tomography Studies

S. Rault, R. Duval, P. Dallemagne, 1997 .

A versatile synthesis of 2-amino-4H-pyrido[1,2-a][1,3,5]triazin-4-ones from 2-aminopyridines

S. Rault, J. Lancelot, Hugues Miel, 2002 .

Influence of the introduction of a solubility enhancer on the formulation of lipidic nanoparticles with improved drug loading rates.

S. Rault, L. Poulain, D. Hennequin, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.

Aurélien Lesnard, S. Rault, N. Azas, 2015, European journal of medicinal chemistry.

The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components

J. Latgé, H. Munier-Lehmann, Aurélien Lesnard, 2015, Antimicrobial Agents and Chemotherapy.

MR 20492 and MR 20494: two indolizinone derivatives that strongly inhibit human aromatase

S. Rault, S. Moslemi, G. Séralini, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

A convenient synthesis of new aminopyrroloindoles via an imminium salt

S. Rault, M. Robba, A. Godard, 1985 .

Synthesis of new L-ascorbic ferulic acid hybrids.

S. Rault, J. Lancelot, M. Bazin, 2007, Molecules.

Multifaceted properties of 1,4‐dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitors

C. Rosano, S. Rault, P. Longo, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis of oxysterols and nitrogenous sterols with antileishmanial and trypanocidal activities.

S. Rault, C. Bories, P. Loiseau, 2006, European journal of medicinal chemistry.

Tau protein aggregation in Alzheimer's disease: An attractive target for the development of novel therapeutic agents.

S. Rault, M. Jouanne, A. Voisin‐Chiret, 2017, European journal of medicinal chemistry.

Novel oxybispyridylboronic acids: synthesis and study of their reactivity in Suzuki-type cross-coupling reactions

Aurélien Lesnard, S. Rault, A. Voisin, 2006 .

An efficient route to 6-(het)aryl-2-methyl-2,3-dihydro-1H-pyridin-4-ones as potential nAChRs ligands

S. Rault, P. Dallemagne, Nicolas Leflemme, 2004 .

Synthesis and preliminary in vivo evaluation of new 2-Aryl-6-methyl-1,2-dihydro-1H-pyridin-4-ones and 2-Aryl-6-methylpiperidin-4-ols, as potential anti-amnesiant agents

S. Rault, T. Freret, M. Boulouard, 2005, Journal of enzyme inhibition and medicinal chemistry.

An Efficient Route to 6‐(Het)aryl‐2‐methyl‐2,3‐dihydro‐1H‐pyridin‐4‐ones as Potential nAChRs Ligands.

S. Rault, P. Dallemagne, Nicolas Leflemme, 2004 .

Efficient synthesis of 2-aryl-6-methyl-2,3-dihydro-1H-pyridin-4-ones

S. Rault, P. Dallemagne, J. Guillon, 2000 .

Synthesis of new linear poly(phenylpyridyl) chains

Jana Sopkova-de Oliveira Santos, Sylvain Rault, Anne Sophie Voisin-Chiret, 2012 .

Synthesis of new phenylpyridyl scaffolds using the Garlanding approach

Jana Sopkova-de Oliveira Santos, S. Rault, F. Corbo, 2010 .

Novel Oxybispyridylboronic Acids: Synthesis and Study of Their Reactivity in Suzuki-Type Cross-Coupling Reactions.

Aurélien Lesnard, S. Rault, A. Voisin, 2007 .

2-bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, a new unexpected bifunctional building block for combinatorial chemistry.

S. Rault, A. Bouillon, J. Lancelot, 2003, Acta crystallographica. Section C, Crystal structure communications.

2-(6-bromopyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane and (6-bromopyridin-3-yl)boronic acid, new bifunctional building blocks for combinatorial chemistry.

S. Rault, A. Bouillon, J. Lancelot, 2003, Acta crystallographica. Section C, Crystal structure communications.

Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I

S. Rault, C. Saturnino, A. Caruso, 2012, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of New Aromatic Pyrrolo[2,1- c] [1,4]benzodiazepines and Pyrrolo[1,2- a] thieno[3,2- e] [1,4]diazepines as Anti-tumoral Agents

P. Renard, S. Rault, V. Lisowski, 2002, Journal of enzyme inhibition and medicinal chemistry.

Conversion of N,N′-bis(tert-butoxycarbonyl)guanidines to N-(N′-tert-butoxycarbonylamidino)ureas

S. Rault, Hugues Miel, 1998 .

A general synthesis of halo-oligopyridines. The Garlanding concept

Sylvain Rault, Anne Sophie Voisin-Chiret, S. Rault, 2009 .

A Convenient Rearrangement of 1-Phenylpyrrole-2-carboxaldehydes into Their 3-Isomers

S. Rault, P. Dallemagne, F. Fabis, 1994 .

Conformational Analysis and 3D QSAR Study on Novel Partial Agonists of 5‐HT3 Receptors

Ronan Bureau, S. Rault, R. Bureau, 1996 .

New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization.

P. Renard, B. Pfeiffer, S. Rault, 2003, Journal of medicinal chemistry.

Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines.

S. Rault, M. Clément, C. Roussakis, 2010, European journal of medicinal chemistry.

New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines.

G. Descamps, S. Rault, M. Clément, 2008, Bioorganic & medicinal chemistry.

3D Pharmacophore, hierarchical methods, and 5-HT4 receptor binding data

Aurélien Lesnard, Ronan Bureau, Sylvain Rault, 2008 .

A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites

P. Roques, S. Rault, G. Snounou, 2021, Microbiology spectrum.

Synthesis and Biological Evaluation of Thienopyrrolizines, a New Family of CDK/GSK-3 Inhibitors

Jana Sopkova-de Oliveira Santos, L. Meijer, S. Rault, 2004, Journal of enzyme inhibition and medicinal chemistry.

On the Synthesis of Pyrrolobenzo[b]thieno[1,4]diazepines

S. Rault, H. El-Kashef, P. Vanelle, 2007 .

Pyrrolothieno[1,4]diazepines. Part V. Study of their chemical reactivity and first synthesis of oxazino[4,3‐c]pyrrolo[1,2‐a]thieno[2,3‐f] [1,4]diazepines

S. Rault, M. Boulouard, P. Dallemagne, 1997 .

Pyirolothieno[1,4]diazepines. Part IV. First synthesis of pyrrolo‐[1,2‐a]thieno[2,3‐f][1,4]diazepine Derivatives

S. Rault, M. Boulouard, P. Dallemagne, 1996 .

Pyrrolothieno[1,4]diazepines part III: Synthesis of amino, hydrazino and mercapto derivatives

S. Rault, M. Boulouard, P. Dallemagne, 1996 .

Pyrrolothieno(1,4)diazepines. Part 1. Synthesis and Study of the Reaction Pathway.

S. Rault, M. Boulouard, P. Dallemagne, 1995 .

Synthesis and combinatorial approach of the reactivity of 6- and 7-arylthieno[3,2-d][1,3]oxazine-2,4-diones

S. Rault, J. Lancelot, Emmanuelle Braud, 2003 .

Formulation of sustained release nanoparticles loaded with a tripentone, a new anticancer agent.

S. Rault, J. Benoit, V. Lisowski, 2006, International journal of pharmaceutics.

Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands

H. Munier-Lehmann, Aurélien Lesnard, S. Rault, 2023, Molecules.

Applicability of the free energies of solvation for the prediction of ecotoxicity: study of chlorophenols.

S. Rault, R. Bureau, F. Briens, 1997, SAR and QSAR in environmental research.

New Trimethoxybenzamides and Trimethoxyphenylureas Derived from Dimethylcarbazole as Cytotoxic Agents. Part I

Aurélien Lesnard, S. Rault, T. Cresteil, 2014 .

Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles.

Aurélien Lesnard, S. Rault, T. Cresteil, 2014, Bioorganic & medicinal chemistry letters.

NOVEL AND EFFICIENT SYNTHESIS OF 5,8-DIMETHYL-9H- CARBAZOL-3-OL VIA A HYDROXYDEBORONATION REACTION

S. Rault, A. Garofalo, A. Caruso, 2007 .

Reactivity of 3-iodoimidazo[1,2-a]pyridines using a Suzuki-type cross-coupling reaction.

S. Rault, A. Gueiffier, V. Collot, 2000, The Journal of organic chemistry.

Suzuki-Type Cross-Coupling Reaction of 3-Iodoindazoles with Aryl Boronic Acids: A General and Flexible Route to 3-Arylindazoles.

S. Rault, P. Dallemagne, P. Bovy, 2010 .

Structural Characterizations of Oligopyridyl Foldamers, α-Helix Mimetics

Jana Sopkova-de Oliveira Santos, Ronan Bureau, Sylvain Rault, 2012, J. Chem. Inf. Model..

Reactivity of 3‐Iodoimidazo[1,2‐a]pyridines Using a Suzuki‐Type Cross‐Coupling Reaction.

S. Rault, A. Gueiffier, V. Collot, 2001 .

First tricyclic oximino derivatives as 5-HT3 ligands.

P Delagrange, P. Renard, B. Pfeiffer, 2001, Bioorganic & medicinal chemistry letters.

Solution-phase parallel synthesis of a 1140-member ureidothiophene carboxylic acid library.

S. Rault, J. Lancelot, Emmanuelle Braud, 2005, Journal of combinatorial chemistry.

Pyrrolo [1,2-a] thieno [3,2-f] 1,4-diazepines. Novel synthesis and X-ray analysis

S. Rault, M. Robba, M. D. Sevricourt, 1979 .

Discovery of a new antileishmanial hit in 8-nitroquinoline series.

S. Rault, N. Azas, M. Laget, 2012, European journal of medicinal chemistry.

Thiaisatoic Anhydrides: Efficient Synthesis under Microwave Heating Conditions and Study of Their Reactivity.

S. Rault, F. Fabis, M. Robba, 1998 .

First direct synthesis of pyrrolo[1,2-a]thieno[3,2-e]- or [2,3-e][1,4]diazepines, thiophene analogues of pyrrolo[2,1-c][1,4]benzodiazepines

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1998 .

Pyrrolothieno[1,4]diazepines: Synthesis of alkoxy derivatives

S. Rault, M. Boulouard, P. Dallemagne, 1995 .

Pyrrolo [1', 2' : 1, 2] pyrazino [6, 5-b] carbazoles

S. Rault, J. Lancelot, M. Robba, 1983 .

NOVEL AND EFFICIENT ACCESS TO THIENO[3,4-c]CINNOLINES

S. Rault, J. Lancelot, H. El-Kashef, 2008 .

A New Boronic‐Acid Based Strategy to Synthesize 4(5)‐(Het)aryl‐1H‐imidazoles.

Jana Sopkova-de Oliveira Santos, S. Rault, A. Bouillon, 2008 .

Pyrido [3, 2-e] pyrrolo [1, 2-a] pyrazines

S. Rault, D. Ladurée, J. Lancelot, 1985 .

In vitro cytotoxicity of carbazole derivatives IV. 5,11-Dimethyl-6H-pyrido[3,2-b]carbazoles substituted on the pyridine ring

S. Rault, P. Gauduchon, M. Robba, 1993 .

In vitro effects of Celiptium and MR 14504 on mature rat Leydig cell testosterone production

S. Rault, S. Carreau, M. Robba, 1997, Cell Biology and Toxicology.

Synthesis of 4-Aminothieno[2,3-c]pyrid-7-one from 4-Aminocyclopenta[b]thiophen-6-one

S. Rault, P. Dallemagne, M. Robba, 1988 .

Virtual Screening Discovery of New Acetylcholinesterase Inhibitors Issued from CERMN Chemical Library

Jana Sopkova-de Oliveira Santos, Aurélien Lesnard, Jean-Hugues Agondanou, 2010, J. Chem. Inf. Model..

Solid phase synthesis of sulphonamides: novel ligands of 5‐HT6 receptors

S. Rault, F. Dauphin, P. Uriac, 2001, The Journal of pharmacy and pharmacology.

Toward Understanding Mcl-1 Promiscuous and Specific Binding Mode

Jana Sopkova-de Oliveira Santos, S. Rault, R. Bureau, 2017, J. Chem. Inf. Model..

Synthesis and CNS Activity of New 3-Amino-3-arylpropionic Acid Derivatives

S. Rault, M. Boulouard, O. Renault, 1999 .

Definition of New Pharmacophores for Nonpeptide Antagonists of Human Urotensin-II. Comparison with the 3D-structure of Human Urotensin-II and URP

Jana Sopkova-de Oliveira Santos, Aurélien Lesnard, Ronan Bureau, 2007, J. Chem. Inf. Model..

An efficient two-step total synthesis of the quaterpyridine nemertelline.

S. Rault, A. Voisin, A. Bouillon, 2003, The Journal of organic chemistry.

Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships

S. Rault, R. Bureau, Elodie Lescot, 2008, Peptides.

Molecular basis of agonist docking in a human GPR103 homology model by site‐directed mutagenesis and structure–activity relationship studies

H. Vaudry, J. Boutin, J. Chuquet, 2014, British journal of pharmacology.

Mutagenicity of nitro- and amino-substituted carbazoles in Salmonella typhimurium. I. Monosubstituted derivatives of 9H-carbazole.

S. Rault, C. Saturnino, P. Gauduchon, 1993, Mutation research.

Pharmacomodulation of a Sulfamide 5-HT6 Receptor Ligand

S. Rault, F. Dauphin, P. Uriac, 2004, Journal of enzyme inhibition and medicinal chemistry.

Chlorofluorocarbon CFCs, potential alternative HCFCs and HFCs, and related chlorinated compounds: mass spectral study, Part II.

S. Rault, Y. Dat, A. Reizian-Fouley, 1997, Ecotoxicology and environmental safety.

The Maximum Common Substructure as a Molecular Depiction in a Supervised Classification Context: Experiments in Quantitative Structure/Biodegradability Relationships

Ronan Bureau, Sylvain Rault, Bruno Crémilleux, 2002, J. Chem. Inf. Comput. Sci..

Molecular Modeling Studies Focused on 5-HT7 versus 5-HT1A Selectivity. Discovery of Novel Phenylpyrrole Derivatives with High Affinity for 5-HT7 Receptors

Aurélien Lesnard, Frédéric Fabis, Ronan Bureau, 2005, J. Chem. Inf. Model..

New hypotheses for the binding mode of 4- and 7-substituted indazoles in the active site of neuronal nitric oxide synthase.

S. Rault, M. Boulouard, P. Schumann-Bard, 2012, Bioorganic & medicinal chemistry.

Protected Indazole Boronic Acid Pinacolyl Esters: Facile Syntheses and Studies of Reactivities in Suzuki—Miyaura Cross‐Coupling and Hydroxydeboronation Reactions.

S. Rault, Elodie Lohou, V. Collot, 2009 .

Protected Indazole Boronic Acid Pinacolyl Esters: Facile Syntheses and Studies of Reactivities in Suzuki-Miyaura Cross-Coupling and Hydroxydeboronation Reactions

S. Rault, Elodie Lohou, V. Collot, 2009 .

Evidence for new non-steroidal human aromatase inhibitors and comparison with equine aromatase inhibition for an understanding of the mammalian active site

S. Rault, S. Moslemi, G. Séralini, 1998 .

Effects of S-21007, a potent 5-HT3 partial agonist, in mouse anxiety.

P. Renard, B. Pfeiffer, S. Rault, 1999, Zhongguo yao li xue bao = Acta pharmacologica Sinica.

Pyrrolo[2,1-c][1,4]benzodiazepines : A mild conversion of thiolactam into amidine.

S. Rault, M. Robba, M. Foloppe, 1992 .

Pyrrolo[2,1-c][1,4]benzodiazepines: synthesis of N-substituted amidines

S. Rault, M. Robba, I. Rault, 1993 .

2‐Azidopyrrolo[2,1‐c][1,4]benzodiazepines. Synthesis of the first cyclic amidine derivatives

S. Rault, Alain-Claude Gillard, 1997 .

Pyrrolo[2,1‐c][1,4]benzodiazepines. Synthesis of new cyclic amidines and fused[a]triazolo, tetrazolo and oxadiazolo derivatives

S. Rault, Alain-Claude Gillard, M. Foloppe, 1997 .

THIAZOLO4,3-C1,4BENZODIAZEPINES. II. SYNTHESIS OF FUSEDATRIAZOLO, TETRAZOLO AND OXADIAZOLO DERIVATIVES

S. Rault, M. Boulouard, M. Robba, 1996 .

Thiazolo[4,3-c][1,4]benzodiazepines. I. Synthesis of amidine derivatives

S. Rault, M. Boulouard, M. Robba, 1995 .

Original and quick access to 4-phenyl-6H-pyrrolo[1,2-a]thieno [3,2-f][1,4]diazepines

S. Rault, P. Sonnet, M. Robba, 1995 .

Pyrrolo[1,2-a][1,4] benzodiazepines : An original three-step synthesis from anthranilonitrile.

S. Rault, M. Robba, I. Rault, 1993 .

Pyrrolo(2,1-c)(1,4)benzodiazepines: A Mild Conversion of Thiolactam into Amidine.

S. Rault, M. Robba, M. Foloppe, 1992 .

New access to 4‐phenyl‐6H‐pyrrolo[1,2‐a]thieno[3,2‐f]‐[1,4]diazepines

S. Rault, P. Sonnet, M. Robba, 1996 .

SYNTHESIS OF NEW 2-AMINOPYRROLO[2,1-c][1,4] BENZODIAZEPINE-5,11-DIONE DERIVATIVES

S. Rault, Alain-Claude Gillard, M. Alkhader, 1996 .

DNA-binding properties of pyrrolo[2,1-c][1,4]benzodiazepine N10-C11 amidines

S. Rault, T. C. Jenkins, D. Thurston, 1996 .

Pyrrolo(2,1‐c)(1,4)benzodiazepines: Synthesis of N‐Substituted Amidines.

S. Rault, M. Robba, I. Rault, 1993 .

Pyrrolo[2,1‐c][1,4]benzodiazepines. Synthesis of New Cyclic Amidines and Fused[a]triazolo, Tetrazolo and Oxadiazolo Derivatives.

S. Rault, Alain-Claude Gillard, M. Foloppe, 1997 .

Pyrrolo(1,2-a)(1,4)benzodiazepines: An Original Three-Step Synthesis from Anthranilonitrile.

S. Rault, M. Robba, I. Rault, 1993 .

ORIGINAL AND QUICK ACESS TO 4-PHENYL-6H-PYRROLO1,2-ATHIENO 3,2-F1,4 DIAZEPINES

S. Rault, P. Sonnet, M. Robba, 1995 .

Pyrrolo[1,2-a]thieno[3,2-f][1,4]diazepines: new 4H and 4H-5,6-dihydro derivatives

S. Rault, M. Robba, I. Rault, 1994 .

Pyrrolo[1,2-a]thieno[3,2-f][1,4]diazepines: An Efficient Synthesis

S. Rault, M. Robba, I. Rault, 1993 .

Thiazolo(4,3-c) (1,4)benzodiazepines. Part 2. Synthesis of Fused(a) triazolo, Tetrazolo and Oxadiazolo Derivatives.

S. Rault, M. Boulouard, M. Robba, 2010 .

2-Azidopyrrolo[2,1-c][1,4]benzodiazepines. Synthesis of the First Cyclic Amidine Derivatives.

S. Rault, Alain-Claude Gillard, 1998 .

Thiazolo(4,3‐c) (1,4)Benzodiazepines. Part 1. Synthesis of Amidine Derivatives.

S. Rault, M. Boulouard, M. Robba, 1996 .

New Access to 4‐Phenyl‐6H‐pyrrolo(1,2‐a)thieno(3,2‐f)(1,4)diazepines.

S. Rault, P. Sonnet, M. Robba, 1996 .

SYNTHESIS OF NEW PHENYLPYRROLIZINONES VIA A MANNICH REACTION

S. Rault, P. Sonnet, P. Dallemagne, 1999 .

Reinvestigation of Rearrangement of Benzodiazepinediones into Quinoleines Under Microwave or Conventional Heating Conditions

S. Rault, Alain-Claude Gillard, A. Hinschberger, 2000 .

Rearrangement of pyrrolo[2,1-c][1,4]benzodiazepines into cyclopenta[b][1,4]benzodiazepines under microwave or conventional heating conditions

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1997 .

A new rearrangement under microwave heating conditions: synthesis of cyclopenta[b][1,4]benzodiazepines and tetrahydrodibenzo[b,fl[1,4]diazepines.

S. Rault, M. Robba, Alain-Claude Gillard, 1995 .

New fused pyrazines. Synthesis of pyrido[3′,2′:4,5]-thieno[2,3-e]pyrrolo[1,2-a]pyrazine derivatives

S. Rault, A. El-Dean, P. Dallemagne, 2000 .

Pyrrolothienopyrazines. IV. Synthese de derives de 1′amino-5 pyrrolo[1,2-a]thieno[2,3-e]pyrazine

S. Rault, J. Lancelot, M. Robba, 1987 .

Synthesis of Tetracyclic Systems: A Convenient Route to [1]Benzothieno [2,3-e]pyrrolo[1,2-a]pyrazine and [1]Benzofuro[2,3-e]pyrrolo[1,2-a]pyrazine Derivatives

S. Rault, M. Robba, M. D. Sevricourt, 1981 .

New Fused Pyrazines. Synthesis of Pyrido[3′,2′:4,5]thieno[2,3‐e]pyrrolo[1,2‐a]pyrazine Derivatives.

S. Rault, A. El-Dean, P. Dallemagne, 2010 .

Pyrrolothienopyrazines. Part 4. Synthesis of Derivatives of 5-Aminopyrrolo(1,2-a)thieno(2,3-e)pyrazine.

S. Rault, J. Lancelot, M. Robba, 1987 .

New Condensed Triheterocyclic Systems; Pyrrolothienopyrimidines.

S. Rault, M. Robba, M. D. Sevricourt, 1980 .

Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

H. Vaudry, Aurélien Lesnard, S. Rault, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of cyclopenta[c]thiophene related compounds as new antitumor agents.

S. Rault, O. Renault, R. Bureau, 2002, Bioorganic & medicinal chemistry.

Synthesis of new bisaryl cyclopentathiophene and thieno-cyclopentoxazolidine derivatives as potential cytotoxic agents

S. Rault, Z. Omran, P. Dallemagne, 2007, Journal of enzyme inhibition and medicinal chemistry.

A First Cyclopenta [c] thiophene Dimer as a New Bivalent Potent Cytotoxic Derivative

S. Rault, P. Dallemagne, Lan Pham Khanh, 2002, Journal of enzyme inhibition and medicinal chemistry.

FIRST SYNTHESIS OF ISOTHIANINHYDRIN, THE SECOND THIOPHENE ISOSTERE OF NINHYDRIN

S. Rault, P. Dallemagne, Lan Pham Khanh, 1999 .

Synthesis and cytotoxic activity against L1210 leukemia of new aminocyclopenta[c]thiophenones.

S. Rault, F. Carreiras, P. Gauduchon, 1994, Chemical & pharmaceutical bulletin.

First Synthesis of Isothianinhydrin, the Second Thiophene Isostere of Ninhydrin.

S. Rault, P. Dallemagne, Lan Pham Khanh, 1999 .

Synthesis and Cytotoxic Activity Against L1210 Leukemia of New Aminocyclopenta(c)thiophenones (IV).

S. Rault, F. Carreiras, P. Gauduchon, 1995 .

YC-1, an activation inductor of soluble guanylyl cyclase.

S. Rault, J. Sopková-de Oliveira Santos, V. Collot, 2000, Acta crystallographica. Section C, Crystal structure communications.

Focus on Microwaves Assisted Halogen-halogen Exchange Reaction Conditions on 2-Halopyridines

S. Rault, Gregory Burzicki, Serge Perato, 2014 .

Conformation Control of Abiotic α-Helical Foldamers

Jana Sopkova-de Oliveira Santos, Sylvain Rault, Anne Sophie Voisin-Chiret, 2013, J. Chem. Inf. Model..

Targeting the BH3 domain of Bcl-2 family proteins. A brief history from natural products to foldamers as promising cancer therapeutic avenues.

S. Rault, M. De Giorgi, A. Voisin‐Chiret, 2013, Current medicinal chemistry.

Using halo (het) arylboronic species to achieve synthesis of foldamers as protein–protein interaction disruptors

S. Rault, A. Voisin‐Chiret, 2012 .

Design and synthesis of thienylpyridyl garlands as non-peptidic alpha helix mimetics and potential protein–protein interactions disruptors

Jana Sopkova-de Oliveira Santos, Sylvain Rault, Anne Sophie Voisin-Chiret, 2011 .

Synthesis of New [2,3′:6′,3′′]TerpyridinesUsing Iterative Cross-Coupling Reactions

Jana Sopkova-de Oliveira Santos, Sylvain Rault, Anne Sophie Voisin-Chiret, 2010 .

Synthesis of Dihalo Bi- and Terpyridines by Regioselective Suzuki—Miyaura Cross-Coupling Reactions.

Jana Sopkova-de Oliveira Santos, S. Rault, Gregory Burzicki, 2009 .

Interaction of S 21007 with 5-HT3 receptors. In vitro and in vivo characterization.

M. Hamon, P. Renard, B. Pfeiffer, 1996, European journal of pharmacology.

Prediction of the Daphnia acute toxicity from heterogeneous data.

S. Rault, R. Bureau, F. Briens, 2001, Chemosphere.

A facile synthetic route to new pyrazoloisoindolones

S. Rault, C. Mahatsekake, Anne-Laure Gérard, 2007 .

Small-animal single-photon emission computed tomographic imaging of the brain serotoninergic systems in wild-type and mdr1a knockout rats.

N. Ginovart, Y. Charnay, S. Rault, 2014, Molecular imaging.

Direct Access to 3-Aminoindazolesby Buchwald-Hartwig C-N Coupling Reaction

S. Rault, Elodie Lohou, V. Collot, 2011 .

Tampering with Cell Division by Using Small‐Molecule Inhibitors of CDK–CKS Protein Interactions

Aurélien Lesnard, S. Rault, M. Miteva, 2015, Chembiochem : a European journal of chemical biology.

ChemInform Abstract: Synthesis of Novel Halopyridinylboronic Acids and Esters. Part 2. 2,4, or 5-Halopyridin-3-yl-boronic Acids and Esters.

S. Rault, A. Bouillon, J. Lancelot, 2002 .

Synthesis of New Avenalumic Carboxamide Derivatives in the Ferulic Series

S. Rault, M. Jouanne, J. Lancelot, 2008 .

Sensitization of ovarian carcinoma cells to Bcl-xL-targeting strategies through indirect modulation of Mcl-1 activity by MR22388, a molecule of the tripentone family

S. Rault, L. Poulain, P. Gauduchon, 2013, Journal of Ovarian Research.

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines.

S. Rault, N. Azas, M. Gasquet, 2008, Bioorganic & medicinal chemistry letters.

Nitrated isomers of 2-(trichloromethyl)quinoline.

S. Rault, J. Sopková-de Oliveira Santos, P. Vanelle, 2008, Acta Crystallographica Section C: Crystal Structure Communications.

Nanocarriers for the targeted treatment of ovarian cancers.

S. Lheureux, S. Rault, P. Gauduchon, 2013, Biomaterials.

Molecular Design Based on 3D-Pharmacophore. Application to 5-HT4 Receptor

Ronan Bureau, Sylvain Rault, Cyril Daveu, 2002, J. Chem. Inf. Comput. Sci..

Molecular Design Based on 3D-Pharmacophore. Application to 5-HT Subtypes Receptors

Ronan Bureau, Sylvain Rault, Cyril Daveu, 2002, J. Chem. Inf. Comput. Sci..

Association of Two 3D QSAR Analyses. Application to the Study of Partial Agonist Serotonin-3 Ligands

Jana Sopkova-de Oliveira Santos, Ronan Bureau, Sylvain Rault, 2001, J. Chem. Inf. Comput. Sci..

Definition of a Pharmacophore for Partial Agonists of Serotonin 5-HT3 Receptors

Ronan Bureau, Sylvain Rault, Cyril Daveu, 1999, J. Chem. Inf. Comput. Sci..

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

Jana Sopkova-de Oliveira Santos, H. Vaudry, S. Rault, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Toward Understanding Mcl-1 Promiscuous and Specific Binding Mode

Jana Sopkova-de Oliveira Santos, S. Rault, R. Bureau, 2017, J. Chem. Inf. Model..

Unusual behaviour of pyridinylboronic acids in the Petasis boronic Mannich reaction

Aurélien Lesnard, S. Rault, A. Voisin, 2006 .

Partial least squares analysis and mixture design for the study of the influence of composition variables on lipidic nanoparticle characteristics.

S. Rault, D. Hennequin, A. Malzert‐Fréon, 2010, Journal of pharmaceutical sciences.

Synthesis and study of the stability of 3b,4,4a-5-tetrahydrothieno[2',3':5,4]cyclopenta[2,3-b]aziridine derivatives

D. Maume, S. Rault, P. Dallemagne, 1987 .

Synthesis and Study of the Stability of 3b,4,4a,5‐Tetrahydrothieno‐(2′,3′:5,4)cyclopenta(2,3‐b)aziridine Derivatives.

D. Maume, S. Rault, P. Dallemagne, 1987 .

Prediction of the fish acute toxicity from heterogeneous data coming from notification files.

S. Rault, R. Bureau, F. Briens, 1999, Chemosphere.

N-Arylsulfonyl-2-vinyltryptamines as new 5-HT6 serotonin receptor Ligands

S. Rault, J. Sapi, J. Laronze, 2006, Journal of enzyme inhibition and medicinal chemistry.

Prediction of acute toxicity in fish by using QSAR methods and chemical modes of action

Ronan Bureau, Sylvain Rault, Alban Lepailleur, 2010, Journal of enzyme inhibition and medicinal chemistry.

2-(6-Bromopyridin-2-yl)-6-methyl-[1,3,6,2]dioxazaborocane, a new stable (pyridin-2-yl)boronic acid derivative.

S. Rault, A. Bouillon, J. Lancelot, 2004, Acta crystallographica. Section C, Crystal structure communications.

The effects of DHEA, 3β-hydroxy-5α-androstane-6,17-dione, and 7-amino-DHEA analogues on short term and long term memory in the mouse

S. Rault, M. Boulouard, L. Kihel, 2009, Steroids.

Receptor- and Ligand-Based Study on Novel 2, 2′-Bithienyl Derivatives as Non-Peptidic AANAT Inhibitors

Xiao Feng, Jana Sopkova-de Oliveira Santos, Ronan Bureau, 2010, J. Chem. Inf. Model..

Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology

Aurélien Lesnard, Ronan Bureau, Sylvain Rault, 2014, J. Chem. Inf. Model..

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

B. Pfeiffer, S. Rault, F. Lezoualc’h, 2009, Bioorganic & medicinal chemistry.

First Synthesis of 1-Phenyl-3-pyrrol-1-ylindan-2-carboxylic Acid, a New Scaffold of Potential Non-peptide Endothelin Receptor Antagonists

S. Rault, P. Dallemagne, J. Guillon, 1999 .