S. Singleton

发表

Nucleic acid hybridization: triplex stability and energetics.

K. Breslauer, G. Plum, D. S. Pilch, 1995, Annual review of biophysics and biomolecular structure.

Inhibitors of Streptococcus pneumoniae Surface Endonuclease EndA Discovered by High-Throughput Screening Using a PicoGreen Fluorescence Assay

Eliza J. R. Peterson, W. Janzen, A. Pingoud, 2013, Journal of biomolecular screening.

Direct evaluation of a mechanism for activation of the RecA nucleoprotein filament.

S. Singleton, A. I. Roca, 2003, Journal of the American Chemical Society.

Molecular basis for nonadditive mutational effects in Escherichia coli dihydrofolate reductase.

S. Benkovic, S. Singleton, C. Wagner, 1995, Biochemistry.

Evidence for dynamics in proteins as a mechanism for ligand dissociation

Andrew L. Lee, Randall V. Mauldin, S. Singleton, 2011, Nature chemical biology.

Direct detection of structurally resolved dynamics in a multiconformation receptor-ligand complex.

Andrew L. Lee, Ashutosh Tripathy, Edward J. Collins, 2011, Journal of the American Chemical Society.

Inhibition of the Escherichia coli RecA protein: zinc(II), copper(II) and mercury(II) trap RecA as inactive aggregates.

S. Singleton, A. M. Lee, 2004, Journal of inorganic biochemistry.

Equilibrium association constants for oligonucleotide-directed triple helix formation at single DNA sites: linkage to cation valence and concentration.

P. Dervan, S. Singleton, 1993, Biochemistry.

Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites.

P. Dervan, S. Singleton, 1992, Biochemistry.

Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study.

P. Dervan, K. Breslauer, G. Plum, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Facile synthesis of a fluorescent deoxycytidine analogue suitable for probing the RecA nucleoprotein filament.

S. Singleton, M. Kanan, C. M. McIntosh, 2001, Organic Letters.

Thermodynamics of oligodeoxyribonucleotide-directed triple helix formation: an analysis using quantitative affinity cleavage titration

P. Dervan, S. Singleton, 1992 .

Stability and Energetics

G. Plum, D. S. Pilch, S. Singleton, 1995 .

Origins of sequence selectivity in homologous genetic recombination: insights from rapid kinetic probing of RecA-mediated DNA strand exchange.

Jie Xiao, S. Singleton, A. M. Lee, 2006, Journal of molecular biology.

Probing the structure of RecA-DNA filaments. Advantages of a fluorescent guanine analog.

Jie Xiao, S. Singleton, A. M. Lee, 2007, Tetrahedron.

Construction and evaluation of a kinetic scheme for RecA‐mediated DNA strand exchange

Jie Xiao, S. Singleton, A. M. Lee, 2006, Biopolymers.

Elucidating a key intermediate in homologous DNA strand exchange: structural characterization of the RecA-triple-stranded DNA complex using fluorescence resonance energy transfer.

Jie Xiao, S. Singleton, 2002, Journal of molecular biology.

State-to-state collisional energy transfer in electronically excited silicon monochloride radicals

S. Singleton, K. McKendrick, 1993 .

The stretched DNA geometry of recombination and repair nucleoprotein filaments.

S. Singleton, J. Xiao, 2001, Biopolymers.

Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli

S. Singleton, L. Yeh, M. Hadimani, 2009, Journal of biomolecular screening.

Synthesis and application of a chain-terminating dinucleotide mRNA cap analog.

S. Singleton, P. Gershon, V. Sharma, 2002, Organic letters.

High-throughput screening for RecA inhibitors using a transcreener adenosine 5'-O-diphosphate assay.

Eliza J. R. Peterson, W. Janzen, S. Singleton, 2012, Assay and drug development technologies.

Novel Inhibitors of E. coli RecA ATPase Activity

S. Singleton, L. Yeh, J. Sexton, 2010, Current chemical genomics.

Inhibition of Escherichia coli RecA by rationally redesigned N-terminal helix.

S. Singleton, D. J. Cline, Shannon L Holt, 2007, Organic & biomolecular chemistry.

Direct Evaluation of a Kinetic Model for RecA‐Mediated DNA‐strand exchange: The Importance of Nucleic Acid Dynamics and Entropy During Homologous Genetic Recombination

Jie Xiao, S. Singleton, A. M. Lee, 2006, Chembiochem : a European journal of chemical biology.

A perspective on biological catalysis

S. Benkovic, S. Singleton, W. R. Cannon, 1996, Nature Structural Biology.

Design and evaluation of a tryptophanless RecA protein with wild type activity.

S. Singleton, M. Berger, A. Roca, 2001, Biochemical and biophysical research communications.

Intein-mediated affinity-fusion purification of the Escherichia coli RecA protein.

S. Singleton, N. Sharma, A. Roca, 2002, Protein expression and purification.

A complementary pair of rapid molecular screening assays for RecA activities.

S. Singleton, T. Wigle, A. M. Lee, 2007, Analytical biochemistry.

Directed molecular screening for RecA ATPase inhibitors.

S. Singleton, T. Wigle, 2007, Bioorganic & medicinal chemistry letters.

A molecular target for suppression of the evolution of antibiotic resistance: inhibition of the Escherichia coli RecA protein by N(6)-(1-naphthyl)-ADP.

S. Singleton, Bu-bing Zeng, A. M. Lee, 2005, Journal of medicinal chemistry.

Rapid metabolic and newborn screening of thyroxine (T4) from dried blood spots by MS/MS.

S. Singleton, D. Chace, J. DiPerna, 2009, Clinica chimica acta; international journal of clinical chemistry.