Danzhou Yang

发表

Jean-Louis Mergny, P. Bates, J. Mergny, 2007, EMBO reports.

G-quadruplex structures and G-quadruplex-interactive compounds.

Danzhou Yang, R. Mathad, 2011, Methods in molecular biology.

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization.

Roger A. Jones, Danzhou Yang, A. Ambrus, 2005, Biochemistry.

Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.

Danzhou Yang, L. Hurley, J. Dai, 2011, Journal of the American Chemical Society.

Resolving the Ligand-Binding Specificity in c-MYC G-Quadruplex DNA: Absolute Binding Free Energy Calculations and SPR Experiment.

P. Cieplak, Danzhou Yang, L. Wickstrom, 2017, The journal of physical chemistry. B.

Structural insights into G-quadruplexes: towards new anticancer drugs.

Danzhou Yang, Keika Okamoto, 2010, Future medicinal chemistry.

Sequence, Stability, and Structure of G‐Quadruplexes and Their Interactions with Drugs

Danzhou Yang, Yuwei Chen, 2012, Current protocols in nucleic acid chemistry.

The 3'-end region of the human PDGFR-β core promoter nuclease hypersensitive element forms a mixture of two unique end-insertion G-quadruplexes.

Danzhou Yang, L. Hurley, M. Carver, 2017, Biochimica et biophysica acta. General subjects.

Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop isomers formed in the nuclease hypersensitive element in the human c-Myc promoter: effect of loops and flanking segments on the stability of parallel-stranded intramolecular G-quadruplexes.

Danzhou Yang, Keika Okamoto, E. Hatzakis, 2010, Biochemistry.

Custom DNA microarrays reveal diverse binding preferences of proteins and small molecules to thousands of G-quadruplexes.

D. Tillo, C. Vinson, Yaron Orenstein, 2020, ACS chemical biology.

The major G-quadruplex formed in the human platelet-derived growth factor receptor β promoter adopts a novel broken-strand structure in K+ solution.

Danzhou Yang, L. Hurley, E. Hatzakis, 2012, Journal of the American Chemical Society.

Pulsed Terahertz Radiation for Sensitive Quantification of Carbonate Minerals

Danzhou Yang, F. Shiraishi, A. Kano, 2019, ACS omega.

Novel DNA Bis-Intercalator XR5944 as a Potent Anticancer Drug—Design and Mechanism of Action

Danzhou Yang, J. Dickerhoff, Adam J Buric, 2021, Molecules.

Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding

Danzhou Yang, Fuyi Wang, Z. Mao, 2018, Nature Communications.

Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.

Danzhou Yang, Ming-Hua Yang, Lingyi Kong, 2022, Journal of the American Chemical Society.

Therapeutic Targets and Drugs II: G-Quadruplex and G-Quadruplex Inhibitors

Danzhou Yang, C. Punchihewa, 2009 .

A simple method for NMR t1 noise suppression.

H. Mo, C. Post, Danzhou Yang, 2017, Journal of magnetic resonance.

Structurally Diverse Alkaloids from the Seeds of Peganum harmala.

Danzhou Yang, Wen Bin, Y. Pei, 2017, Journal of natural products.

High-Throughput Screening of G-Quadruplex Ligands by FRET Assay.

Danzhou Yang, D. P. Flaherty, Kai-Bo Wang, 2019, Methods in molecular biology.

Decoding regulatory associations of G-quadruplex with epigenetic and transcriptomic functional components

Danzhou Yang, J. Wan, Sheng Liu, 2022, Frontiers in Genetics.

Molecular Recognition of the Hybrid-Type G-Quadruplexes in Human Telomeres

Danzhou Yang, Luying Chen, Guanhui Wu, 2019, Molecules.

DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944.

Danzhou Yang, Clement Lin, 2015, Current topics in medicinal chemistry.

Solution structure of a 2:1 complex of anticancer drug XR5944 with TFF1 estrogen response element: insights into DNA recognition by a bis-intercalator

Danzhou Yang, R. Mathad, N. Sidell, 2014, Nucleic acids research.

Intercalation of XR5944 with the estrogen response element is modulated by the tri-nucleotide spacer sequence between half-sites

Danzhou Yang, C. Kallen, R. Mathad, 2011, The Journal of Steroid Biochemistry and Molecular Biology.

Solution Structure of Ternary Complex of Berberine Bound to a dGMP-Fill-In Vacancy G-Quadruplex Formed in the PDGFR-β Promoter.

Danzhou Yang, J. Dickerhoff, Kai-Bo Wang, 2021, Journal of the American Chemical Society.

A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA

J. H. Boom, N. Farrell, Danzhou Yang, 1995, Nature Structural Biology.

A Series of β-Carboline Alkaloids from the Seeds of Peganum harmala Show G-Quadruplex Interactions.

Danzhou Yang, Jian Wang, Y. Pei, 2016, Organic letters.

Total and semisynthesis and in vitro studies of both enantiomers of 20-fluorocamptothecin.

Y. Pommier, Danzhou Yang, Smitha Antony, 2005, Bioorganic & medicinal chemistry letters.

A direct and nondestructive approach to determine the folding structure of the I-motif DNA secondary structure by NMR.

Danzhou Yang, L. Hurley, A. Ambrus, 2009, Journal of the American Chemical Society.

Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length

Danzhou Yang, Luying Chen, J. Dickerhoff, 2019, ACS omega.

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

Roger A. Jones, Danzhou Yang, A. Ambrus, 2006, Nucleic acids research.

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

Roger A. Jones, Danzhou Yang, C. Punchihewa, 2007, Nucleic acids research.

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

Roger A. Jones, Danzhou Yang, L. Hurley, 2006, Nucleic acids research.

Diffusion ordered NMR spectroscopy for analysis of DNA secondary structural elements

Danzhou Yang, A. Ambrus, 2008 .

Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements.

Danzhou Yang, A. Ambrus, 2007, Analytical biochemistry.

PDGFR-β Promoter Forms a Vacancy G-Quadruplex that Can be Filled-in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.

Danzhou Yang, J. Dickerhoff, Guanhui Wu, 2020, Journal of the American Chemical Society.

Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures.

Danzhou Yang, Clement Lin, S. Sakai, 2018, Angewandte Chemie.

Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

Roger A. Jones, Danzhou Yang, C. Punchihewa, 2007, Nucleic acids research.

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution.

Roger A. Jones, Thomas S. Dexheimer, Danzhou Yang, 2006, Journal of the American Chemical Society.

NMR Studies of G-Quadruplex Structures and G-Quadruplex-Interactive Compounds.

Danzhou Yang, Clement Lin, J. Dickerhoff, 2019, Methods in molecular biology.

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.

Danzhou Yang, L. Hurley, Christine E. Kaiser, 2017, Journal of the American Chemical Society.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry protocol for monitoring the progress of enzymatic (13)C/(15)N-labeled DNA syntheses.

Danzhou Yang, Á. Somogyi, A. Ambrus, 2005, Analytical biochemistry.

Fluorescence Spectral Properties of the Anticancer Drug Topotecan by Steady‐State and Frequency Domain Fluorometry with One‐Photon and Multi‐Photon Excitation

J. Lakowicz, Danzhou Yang, I. Gryczynski, 1999, Photochemistry and photobiology.

The tri-nucleotide spacer sequence between estrogen response element half-sites is conserved and modulates ERα-mediated transcriptional responses

Danzhou Yang, C. Kallen, N. Sidell, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

G-Quadruplex in the NRF2 mRNA 5′ Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress

Qin M. Chen, Danzhou Yang, J. Strom, 2016, Molecular and Cellular Biology.

RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes

L. Hui, Danzhou Yang, D. Durantel, 2021, Gut.

Polymorphism of human telomeric quadruplex structures.

Danzhou Yang, J. Dai, M. Carver, 2008, Biochimie.

c-MYC promoter G-quadruplex formed at the 5′-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

Danzhou Yang, R. Mathad, J. Dai, 2011, Nucleic acids research.

I-Motif Structures Formed in the Human c-MYC Promoter Are Highly Dynamic–Insights into Sequence Redundancy and I-Motif Stability

Danzhou Yang, L. Hurley, J. Dai, 2010 .

G-Quadruplex in the NRF 2 mRNA 5 = Untranslated Region Regulates De Novo NRF 2 Protein Translation under Oxidative Stress

Qin M. Chen, Danzhou Yang, J. Strom, 2016 .

Structure of the Biologically Relevant G-Quadruplex in The c-MYC Promoter

Danzhou Yang, L. Hurley, 2006, Nucleosides, nucleotides & nucleic acids.

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC.

Danzhou Yang, M. Cushman, M. S. Elsayed, 2019, Journal of the American Chemical Society.

Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition

Danzhou Yang, Ta-Chau Chang, J. Dai, 2019, Nucleic acids research.

A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription.

Danzhou Yang, M. Carver, Danzhou Yang, 2016, Journal of the American Chemical Society.

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

Roger A. Jones, Danzhou Yang, J. Dai, 2009, Nucleic acids research.

The Major G-Quadruplex Formed in the Human BCL-2 Proximal Promoter Adopts a Parallel Structure with a 13-nt Loop in K+ Solution

Prashansa Agrawal, Danzhou Yang, R. Mathad, 2014, Journal of the American Chemical Society.

Correction to “The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure”

Hyun-Jin Kang, Danzhou Yang, S. Hecht, 2016, Journal of the American Chemical Society.

The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure

Hyun-Jin Kang, Danzhou Yang, S. Hecht, 2014, Journal of the American Chemical Society.

DDX5 helicase resolves G-quadruplex and is involved in MYC gene transcriptional activation

Danzhou Yang, Elizabeth J. Tran, Guanhui Wu, 2019, Proceedings of the National Academy of Sciences.

Human Telomeric G-Quadruplex Structures and G-Quadruplex-Interactive Compounds.

Danzhou Yang, Clement Lin, 2017, Methods in molecular biology.

Structure-Dependent Binding of hnRNPA1 to Telomere RNA.

Yan Xu, Danzhou Yang, Takumi Ishizuka, 2017, Journal of the American Chemical Society.

G-Quadruplex DNA and RNA

Danzhou Yang, 2019, Methods in molecular biology.

Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer.

L. Zhang, Danzhou Yang, Clement Lin, 2015, Analytical chemistry.

Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes

Danzhou Yang, M. Carver, K. Guo, 2013, Nucleic acids research.

DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting.

Danzhou Yang, Luying Chen, S. Sakai, 2022, Accounts of chemical research.

G-Quadruplex Nucleic Acids: Methods and Protocols

Danzhou Yang, Clement Lin, 2019, Methods in Molecular Biology.

The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downre

Danzhou Yang, L. Hurley, S. Camp, 2017, Journal of the American Chemical Society.

Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes

Danzhou Yang, J. Dai, J. Dickerhoff, 2021, Nucleic acids research.

DNA Interactions of Two Clinical Camptothecin Drugs Stabilize Their Active Lactone Forms

Thomas G. Burke, Danzhou Yang, T. Burke, 1998 .

Ligand Selectivity in the Recognition of Protoberberine Alkaloids by Hybrid-2 Human Telomeric G-Quadruplex: Binding Free Energy Calculation, Fluorescence Binding, and NMR Experiments

Danzhou Yang, L. Wickstrom, J. Xia, 2019, Molecules.

DNA G-quadruplex and its potential as anticancer drug target

Danzhou Yang, Clement Lin, B. Onel, 2014, Science China Chemistry.

Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element.

D. V. Von Hoff, Danzhou Yang, L. Hurley, 2006, Seminars in oncology.

Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity

Yanbin Zhang, Xiaohua Wu, F. Yuan, 2000 .

Allosteric Modifiers of Hemoglobin: Potential Applications in Red Cell Storage and Liposome-Encepsulated Hemoglobin Development

Danzhou Yang, T. Burke, Stean Kruszeweki, 1998 .

DNA sequence selectivity of human topoisomerase I‐mediated DNA cleavage induced by camptothecin

Danzhou Yang, C. Punchihewa, M. Carver, 2009, Protein science : a publication of the Protein Society.

Human topoisomerase I C-terminal domain fragment containing the active site tyrosine is a molten globule: implication for the formation of competent productive complex.

Danzhou Yang, C. Punchihewa, J. Dai, 2007, Journal of structural biology.

XR5944: A potent inhibitor of estrogen receptors

Danzhou Yang, C. Punchihewa, N. Sidell, 2007, Molecular Cancer Therapeutics.

Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.

Danzhou Yang, L. Hurley, V. Gokhale, 2013, Topics in current chemistry.

Novel DNA Bis-intercalation by MLN944, a Potent Clinical Bisphenazine Anticancer Drug*

Danzhou Yang, A. Ooi, C. Punchihewa, 2004, Journal of Biological Chemistry.

Electrophoretic Mobility Shift Assay and Dimethyl Sulfate Footprinting for Characterization of G-Quadruplexes and G-Quadruplex-Protein Complexes.

Danzhou Yang, Clement Lin, Daekyu Sun, 2019, Methods in molecular biology.

Subnanomolar Sensitive Stable Isotopic Determination in CO2 by Tunable Infrared Laser Absorption Spectroscopy.

Danzhou Yang, Y. Sakairi, S. Sakai, 2022, Analytical chemistry.

Custom G4 Microarrays Reveal Selective G-Quadruplex Recognition of Small Molecule BMVC: A Large-Scale Assessment of Ligand Binding Selectivity

D. Tillo, C. Vinson, Danzhou Yang, 2020, Molecules.

High-Precision Simultaneous 18O/16O, 13C/12C, and 17O/16O Analyses for Microgram Quantities of CaCO3 by Tunable Infrared Laser Absorption Spectroscopy.

M. Zahniser, Danzhou Yang, J. McManus, 2017, Analytical chemistry.

Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA

Danzhou Yang, N. Deng, J. Dickerhoff, 2021, International journal of molecular sciences.

Combining Alchemical Transformation with Physical Pathway to Accelerate Absolute Binding Free Energy Calculations of Charged Ligands to Enclosed Binding Sites.

E. Gallicchio, Danzhou Yang, L. Wickstrom, 2020, Journal of chemical theory and computation.

I-motif structures formed in the human c-MYC promoter are highly dynamic--insights into sequence redundancy and I-motif stability.

Danzhou Yang, L. Hurley, J. Dai, 2010 .

Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.

A. Wang, Danzhou Yang, D. Yang, 1995, Biochemistry.

DNA G-quadruplex and its potential as anticancer drug target.

Danzhou Yang, Onel Buket, Lin Clement, 2014, Science China. Chemistry.

Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution.

Danzhou Yang, S. A. McLuckey, J. Dickerhoff, 2021, Journal of medicinal chemistry.

Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer.

Danzhou Yang, Clement Lin, Gang Chen, 2015, Analytical chemistry.

RNA helicase DDX5 enables STAT1 mRNA translation and interferon signaling in hepatitis B virus replicating hepatocytes

Danzhou Yang, Jiazeng Sun, O. Andrisani, 2020, bioRxiv.

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC.

Danzhou Yang, M. Cushman, M. S. Elsayed, 2019, Journal of the American Chemical Society.

Structural effect of intra-strand cisplatin-crosslink on palindromic DNA sequences.

G. A. van der Marel, A. Wang, Danzhou Yang, 1996, Journal of biomolecular structure & dynamics.