S. Beggiato

L. Ferraro, C. Bignozzi, S. Beggiato, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study.

L. Ferraro, S. Beggiato, S. Velaga, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice

M. A. De Luca, L. Ferraro, S. Beggiato, 2017, Front. Psychiatry.

Effects of Ultramicronized Palmitoylethanolamide on Mitochondrial Bioenergetics, Cerebral Metabolism, and Glutamatergic Transmission: An Integrated Approach in a Triple Transgenic Mouse Model of Alzheimer's Disease

T. Cassano, S. Beggiato, R. Canese, 2022, Frontiers in Aging Neuroscience.

Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid

R. Schwarcz, S. Beggiato, N. Goeden, 2017, Developmental Neuroscience.

Study of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity Ligation Assay

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2021, Neuromethods.

Detection, Analysis, and Quantification of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity Ligation Assay

K. Fuxe, N. Belluardo, D. Borroto-Escuela, 2018 .

Bile salt-coating modulates the macrophage uptake of nanocores constituted by a zidovudine prodrug and enhances its nose-to-brain delivery.

L. Ferraro, S. Beggiato, E. Leo, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia

K. Fuxe, A. Rivera, D. Borroto-Escuela, 2020, Cells.

Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson's disease and its treatment.

K. Fuxe, L. Agnati, L. Ferraro, 2014, Current protein & peptide science.

Palmitoylethanolamide Blunts Amyloid-β42-Induced Astrocyte Activation and Improves Neuronal Survival in Primary Mouse Cortical Astrocyte-Neuron Co-Cultures.

L. Ferraro, S. Tanganelli, S. Beggiato, 2017, Journal of Alzheimer's disease : JAD.

Use of Superfused Synaptosomes to Understand the Role of Receptor–Receptor Interactions as Integrative Mechanisms in Nerve Terminals from Selected Brain Region

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2018 .

Biological activity of new bioactive steroids deriving from biotransformation of cortisone

L. Ferraro, S. Beggiato, G. Valacchi, 2022, Microbial Cell Factories.

Prenatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin produces alterations in cortical neuron development and a long-term dysfunction of glutamate transmission in rat cerebral cortex

L. Ferraro, S. Tanganelli, S. Beggiato, 2012, Neurochemistry International.

Improved functional recovery in rat spinal cord injury induced by a drug combination administered via an implantable polymeric delivery system.

L. Ferraro, S. Beggiato, M. L. Focarete, 2020, Journal of neurotrauma.

Alterations in rat prefrontal cortex kynurenic acid levels are involved in the enduring cognitive dysfunctions induced by tetrahydrocannabinol exposure during the adolescence

L. Ferraro, R. Schwarcz, S. Beggiato, 2022, Frontiers in Psychiatry.

GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5.

L. Ferraro, S. Tanganelli, S. Beggiato, 2011, Pharmacological reports : PR.

CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice

L. Ferraro, S. Beggiato, L. Calzà, 2016, Genes, brain, and behavior.

Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,212-2 on rat glutamate transmission and cognitive functions

L. Ferraro, S. Tanganelli, T. Cassano, 2009, Journal of Neural Transmission.

Nasal biocompatible powder of geraniol oil complexed with cyclodextrins for neurodegenerative diseases: Physicochemical characterization and in vivo evidences of nose to brain delivery.

L. Ferraro, S. Beggiato, E. Leo, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration

L. Ferraro, S. Beggiato, M. C. Bonferoni, 2019, Pharmaceutics.

Indomethacin co-crystals and their parent mixtures: does the intestinal barrier recognize them differently?

L. Ferraro, S. Beggiato, F. Spizzo, 2015, Molecular pharmaceutics.

Brain uptake of a Zidovudine prodrug after nasal administration of solid lipid microparticles.

L. Ferraro, S. Beggiato, E. Leo, 2014, Molecular pharmaceutics.

CHF5074 restores visual memory ability and pre‐synaptic cortical acetylcholine release in pre‐plaque Tg2576 mice

L. Ferraro, S. Beggiato, L. Calzà, 2013, Journal of neurochemistry.

Brain targeting of resveratrol by nasal administration of chitosan‐coated lipid microparticles

L. Ferraro, S. Beggiato, A. Dalpiaz, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Prenatal THC exposure raises kynurenic acid levels in the prefrontal cortex of adult rats

L. Ferraro, R. Schwarcz, S. Beggiato, 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Nasal administration of nanoencapsulated geraniol/ursodeoxycholic acid conjugate: Towards a new approach for the management of Parkinson's disease.

L. Ferraro, S. Beggiato, E. Leo, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Unfolding New Roles for Guanine-Based Purines and Their Metabolizing Enzymes in Cancer and Aging Disorders

S. Beggiato, P. Di Iorio, M. Ronci, 2021, Frontiers in Pharmacology.

Zidovudine and ursodeoxycholic acid conjugation: design of a new prodrug potentially able to bypass the active efflux transport systems of the central nervous system.

S. Beggiato, A. Dalpiaz, A. Medici, 2012, Molecular pharmaceutics.

Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases

K. Fuxe, Z. Díaz-Cabiale, D. Borroto-Escuela, 2021, Cells.

Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo

K. Fuxe, L. Ferraro, S. Tanganelli, 2013, The European journal of neuroscience.

Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease

Masahiko Watanabe, L. Ferraro, S. Tanganelli, 2012, Neurobiology of Disease.

Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats

L. Ferraro, S. Beggiato, T. Rubino, 2014, Neurobiology of Disease.

Pros and Cons of Pharmacological Manipulation of cGMP-PDEs in the Prevention and Treatment of Breast Cancer

S. Beggiato, P. Di Iorio, F. Caciagli, 2021, International journal of molecular sciences.

Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2020, Pharmacological Reports.

Astrocytic Mechanisms Involving Kynurenic Acid Control Δ9-Tetrahydrocannabinol-Induced Increases in Glutamate Release in Brain Reward-Processing Areas

M. Pistis, L. Ferraro, R. Schwarcz, 2018, Molecular Neurobiology.

In Vivo Microdialysis Technique Applications to Understand the Contribution of Receptor–Receptor Interactions to the Central Nervous System Signaling

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2018 .

Astrocytic palmitoylethanolamide pre-exposure exerts neuroprotective effects in astrocyte-neuron co-cultures from a triple transgenic mouse model of Alzheimer's disease.

L. Ferraro, T. Cassano, S. Beggiato, 2020, Life sciences.

Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice.

L. Ferraro, S. Tanganelli, T. Cassano, 2015, Journal of Alzheimer's disease : JAD.

Striatal adenosine–cannabinoid receptor interactions in rats over‐expressing adenosine A2A receptors

K. Fuxe, L. Ferraro, S. Beggiato, 2016, Journal of neurochemistry.

Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex

K. Fuxe, L. Ferraro, S. Tanganelli, 2014, Neuropharmacology.

Exploring the use of spray congealing to produce solid dispersions with enhanced indomethacin bioavailability: In vitro characterization and in vivo study

L. Ferraro, S. Beggiato, A. Dalpiaz, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes

Fabio Vivarelli, Moreno Paolini, Donatella Canistro, 2018, Front. Pharmacol..

Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2016, Journal of neurochemistry.

The Dual Role of Glutamatergic Neurotransmission in Alzheimer’s Disease: From Pathophysiology to Pharmacotherapy

T. Cassano, S. Beggiato, A. Wawrzyniak, 2020, International journal of molecular sciences.

Influence of polymeric microcarriers on the in vivo intranasal uptake of an anti-migraine drug for brain targeting.

L. Ferraro, S. Beggiato, S. Velaga, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Neurotensin as Modulator of Basal Ganglia- Thalamocortical Motor Circuit – Emerging Evidence for Neurotensin NTS1 Receptor as a Potential Target in Parkinson's Disease

K. Fuxe, L. Ferraro, S. Tanganelli, 2012 .

Neurotensin regulates cortical glutamate transmission by modulating N‐methyl‐D‐aspartate receptor functional activity: An in vivo microdialysis study

K. Fuxe, L. Ferraro, S. Tanganelli, 2011, Journal of neuroscience research.

A2A/D2 receptor heteromerization in a model of Parkinson's disease. Focus on striatal aminoacidergic signaling

K. Fuxe, L. Ferraro, S. Tanganelli, 2012, Brain Research.

Chronic Oral Palmitoylethanolamide Administration Rescues Cognitive Deficit and Reduces Neuroinflammation, Oxidative Stress, and Glutamate Levels in A Transgenic Murine Model of Alzheimer’s Disease

L. Ferraro, T. Cassano, S. Beggiato, 2020, Journal of clinical medicine.

The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

K. Fuxe, A. Rivera, D. Borroto-Escuela, 2021, Frontiers in Pharmacology.

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2021, Frontiers in Pharmacology.

Time of Day-Dependent Alterations in Hippocampal Kynurenic Acid, Glutamate, and GABA in Adult Rats Exposed to Elevated Kynurenic Acid During Neurodevelopment

Katherine M. Rentschler, C. Wright, S. Beggiato, 2021, Frontiers in Psychiatry.

Kynurenine pathway is altered in BDNF Val66Met knock-in mice: Effect of physical exercise

L. Ferraro, S. Beggiato, M. Popoli, 2020, Brain, Behavior, and Immunity.

The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons

K. Fuxe, D. Borroto-Escuela, L. Ferraro, 2021, Pharmacological Reports.

A Novel Mechanism of Cocaine to Enhance Dopamine D2-Like Receptor Mediated Neurochemical and Behavioral Effects. An In Vivo and In Vitro Study

K. Fuxe, D. Marcellino, L. Ferraro, 2012, Neuropsychopharmacology.

Nanomolar concentrations of cocaine enhance D2-like agonist-induced inhibition of the K+-evoked [3H]-dopamine efflux from rat striatal synaptosomes: a novel action of cocaine

K. Fuxe, D. Marcellino, L. Agnati, 2010, Journal of Neural Transmission.

Long-lasting alterations of hippocampal GABAergic neurotransmission in adult rats following perinatal Δ9-THC exposure

L. Ferraro, S. Tanganelli, V. Cuomo, 2017, Neurobiology of Learning and Memory.

Palmitoylethanolamide (PEA) as a Potential Therapeutic Agent in Alzheimer’s Disease

L. Ferraro, S. Beggiato, M. C. Tomasini, 2019, Front. Pharmacol..

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

K. Fuxe, A. Rivera, Z. Díaz-Cabiale, 2018, Front. Synaptic Neurosci..

GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons.

L. Ferraro, S. Tanganelli, S. Beggiato, 2016, Alcohol and alcoholism.

Striatal NTS1, dopamine D2 and NMDA receptor regulation of pallidal GABA and glutamate release – a dual‐probe microdialysis study in the intranigral 6‐hydroxydopamine unilaterally lesioned rat

K. Fuxe, L. Ferraro, S. Tanganelli, 2012, The European journal of neuroscience.

Astrocytic Mechanisms Involving Kynurenic Acid Control Δ9-Tetrahydrocannabinol-Induced Increases in Glutamate Release in Brain Reward-Processing Areas

M. Pistis, L. Ferraro, R. Schwarcz, 2018, Molecular Neurobiology.

Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease

L. Ferraro, S. Beggiato, K. Varani, 2014, Neurobiology of Disease.

In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5

L. Ferraro, S. Beggiato, M. C. Tomasini, 2018, Front. Pharmacol..

GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor

L. Ferraro, S. Tanganelli, S. Beggiato, 2013, Synapse.

The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties.

L. Ferraro, S. Tanganelli, S. Beggiato, 2013, Current medicinal chemistry.

Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia.

K. Fuxe, L. Agnati, D. Borroto-Escuela, 2014, Current protein & peptide science.

Palmitoylethanolamide blunts Aβ 42 -induced astrocyte activation and improves neuronal survival in primary mouse cortical astrocyte-neuron co-cultures.

L. Ferraro, S. Tanganelli, S. Beggiato, 2017 .

GET 73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons

L. Ferraro, S. Tanganelli, S. Beggiato, 2016 .

Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex

K. Fuxe, L. Ferraro, S. Tanganelli, 2014, Neuropharmacology.

Indomethacin co-crystals and their parent mixtures: does the intestinal barrier recognize them differently?

L. Ferraro, S. Beggiato, F. Spizzo, 2015, Molecular pharmaceutics.

Dimeric ferulic acid conjugate as a prodrug for brain targeting after nasal administration of loaded solid lipid microparticles

S. Beggiato, M. C. Bonferoni, L. Catenacci, 2023, Expert opinion on drug delivery.

GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR_5

L. Ferraro, S. Tanganelli, S. Beggiato, 2011, Pharmacological reports : PR.

Prenatal MAM exposure raises kynurenic acid levels in the prefrontal cortex of adult rats.

S. Beggiato, J. Ruda-Kucerova, T. Stark, 2024, Pharmacological reports : PR.

GET73 modulates lipopolysaccharide- and ethanol-induced increase in cytokine/chemokine levels in primary cultures of microglia of rat cerebral cortex.

S. Beggiato, M. C. Tomasini, A. Loche, 2024, Pharmacological reports : PR.

Supramolecular eutectogel as new oral paediatric delivery system to enhance benznidazole bioavailability.

B. Perissutti, S. Beggiato, A. Dalpiaz, 2024, International journal of pharmaceutics.

Chlorogenic acid permeation across intestinal cell monolayers: Influence by circadian rhythms in the presence of other natural polyphenols and by dopaminergic neuronal-like cells

S. Beggiato, V. Bertagnolo, A. Dalpiaz, 2024, Journal of Functional Foods.

Cognitive dysfunction and impaired neuroplasticity following repeated exposure to the synthetic cannabinoid JWH‐018 in male mice

L. Ferraro, F. Fumagalli, S. Beggiato, 2023, British journal of pharmacology.