G. Sfyroera

发表

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

Sheng Li, John D. Lambris, Daniel Ricklin, 2010, Proceedings of the National Academy of Sciences.

Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin.

John D Lambris, J. Lambris, G. Sfyroera, 2004, Virology.

The Extracellular Adherence Protein from Staphylococcus aureus Inhibits the Classical and Lectin Pathways of Complement by Blocking Formation of the C3 Proconvertase

John D Lambris, D. Ricklin, J. Lambris, 2014, Journal of Immunology.

Attenuation of Staphylococcus aureus–Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb

D. Ricklin, J. Lambris, B. Garcia, 2015, The Journal of Immunology.

A structural basis for complement inhibition by Staphylococcus aureus

Daniel Ricklin, John D Lambris, Paola Magotti, 2007, Nature Immunology.

Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysine acetylation and mass spectrometry

J. Lambris, Hui Chen, G. Sfyroera, 2008, Journal of the American Society for Mass Spectrometry.

Commensal microbiota modulate gene expression in the skin

Jonathan R. Brestoff, Jacquelyn S. Meisel, E. Grice, 2018, Microbiome.

Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode

John D Lambris, E. Volokhina, D. Ricklin, 2016, The EMBO journal.

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis.

John D Lambris, J. Lambris, G. Sfyroera, 2010, Blood.

A protective role for the fifth complement component (c5) in allergic airway disease.

John D Lambris, J. Lambris, G. Sfyroera, 2006, American journal of respiratory and critical care medicine.

Complement activation is critical to airway hyperresponsiveness after acute ozone exposure.

John D Lambris, J. Lambris, E. Gelfand, 2004, American journal of respiratory and critical care medicine.

Restoration of Complement-Enhanced Neutralization of Vaccinia Virus Virions by Novel Monoclonal Antibodies Raised against the Vaccinia Virus Complement Control Protein

J. Lambris, G. Sfyroera, S. Isaacs, 2003, Journal of Virology.

C3a Receptor Ciona intestinalis of Structural and Functional Characterization Receptor in an Invertebrate Species: First Identification of a Chemotactic

J. Lambris, G. Sfyroera, R. Santis, 2006 .

Cellular Assay C5a: Insights from a Novel Label-Free Desarginated Physiological Concentrations of C5a Receptor-Dependent Cell Activation by

John D Lambris, P. Monk, D. Ricklin, 2012 .

Molecular cloning of the beta subunit of complement component eight of rainbow trout.

J. Lambris, G. Sfyroera, A. Kazantzi, 2003, Developmental and comparative immunology.

3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties.

P. van Endert, G. Sfyroera, D. Mastellos, 2015, Journal of medicinal chemistry.

Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity

J. Lambris, G. Sfyroera, T. Mollnes, 2010, Innate immunity.

Inhibition of Complement and CD14 Attenuates the Escherichia coli-Induced Inflammatory Response in Porcine Whole Blood

G. Sfyroera, G. Kotwal, T. Mollnes, 2008, Infection and Immunity.

Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement.

John D Lambris, J. Lambris, G. Sfyroera, 2007, Molecular immunology.

Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin.

John D Lambris, J. Lambris, G. Sfyroera, 2006, Journal of medicinal chemistry.

Electrostatic Modeling Predicts the Activities of Orthopoxvirus Complement Control Proteins1

Dimitrios Morikis, John D. Lambris, Madan Katragadda, 2005, The Journal of Immunology.

Protection of Nonself Surfaces from Complement Attack by Factor H-Binding Peptides: Implications for Therapeutic Medicine

John D. Lambris, Bo Nilsson, Daniel Ricklin, 2011, The Journal of Immunology.

MedicinePeptides: Implications for Therapeutic Complement Attack by Factor H-Binding Protection of Nonself Surfaces from

John D Lambris, B. Nilsson, K. Ekdahl, 2011 .

Edinburgh Research Explorer A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor Protein Family

D. Ricklin, J. Lambris, V. M. Holers, 2010 .

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor Protein Family1

D. Ricklin, J. Lambris, M. Hammel, 2009, The Journal of Immunology.

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor

D. Ricklin, J. Lambris, V. M. Holers, 2009 .

Correction: Protection of nonself surfaces from complement attack by factor h-binding peptides: implications for therapeutic medicine

B. Nilsson, K. Ekdahl, D. Ricklin, 2012, The Journal of Immunology.

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.

John D Lambris, J. Lambris, J. Whitsett, 2006, The Journal of clinical investigation.

C3a Receptor Ciona intestinalis Characterization of Structural and Functional Receptor in an Invertebrate Species: First Identification of a Chemotactic

J. Lambris, G. Sfyroera, R. Santis, 2010 .

Ancient origin of the complement system: emerging invertebrate models.

J. Lambris, G. Sfyroera, S. Giacomelli, 2007, Advances in experimental medicine and biology.

First Identification of a Chemotactic Receptor in an Invertebrate Species: Structural and Functional Characterization of Ciona intestinalis C3a Receptor

J. Lambris, G. Sfyroera, M. Pinto, 2006, The Journal of Immunology.

Cloning and purification of the rainbow trout fifth component of complement (C5).

W. T. Moore, John D Lambris, S. Franchini, 2000, Developmental and comparative immunology.

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo.

John D Lambris, J. Lambris, G. Sfyroera, 2007, Blood.

From discovery to approval: A brief history of the compstatin family of complement C3 inhibitors.

D. Ricklin, G. Sfyroera, D. Mastellos, 2021, Clinical immunology.

Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates.

D. Ricklin, J. Lambris, G. Sfyroera, 2020, Clinical immunology.

Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors

D. Ricklin, J. Lambris, P. Gros, 2022, Nature Communications.

The preadolescent acne microbiome: A prospective, randomized, pilot study investigating characterization and effects of acne therapy

E. Grice, G. Sfyroera, A. Yan, 2017, Pediatric dermatology.

Cloning and structure of three rainbow trout C3 molecules: a plausible explanation for their functional diversity.

J. Lambris, G. Sfyroera, I. Zarkadis, 2001, Developmental and comparative immunology.

Blocking Formation of the C3 Proconvertase and Lectin Pathways of Complement by Inhibits the Classical Staphylococcus aureus The Extracellular Adherence Protein from

D. Ricklin, J. Lambris, K. Ramyar, 2014 .

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor Protein Family 1

D. Ricklin, J. Lambris, M. Hammel, 2010 .

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor 1

D. Ricklin, J. Lambris, M. Hammel, 2009 .

Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus*

John D Lambris, M. Pop, D. Ricklin, 2007, Journal of Biological Chemistry.

C5a Receptor-Dependent Cell Activation by Physiological Concentrations of Desarginated C5a: Insights from a Novel Label-Free Cellular Assay

John D Lambris, P. Monk, D. Ricklin, 2012, The Journal of Immunology.

Molecular cloning of leukocyte cell-derived chemotaxin 2 in rainbow trout.

G. Sfyroera, A. Kazantzi, I. Zarkadis, 2005, Fish & shellfish immunology.

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coli sepsis

J. Lambris, G. Sfyroera, F. Taylor, 2010 .

Rare Loss-of-Function Mutation in Complement Component C3 Provides Insight into Molecular and Pathophysiological Determinants of Complement Activity

Bo Nilsson, Yiannis N Kaznessis, Daniel Ricklin, 2015, The Journal of Immunology.

Determinants of Complement Activity into Molecular and Pathophysiological InsightComplement Component C 3 Provides Rare Loss-of-Function Mutation in Ekdahl

John D Lambris, B. Nilsson, K. Ekdahl, 2015 .

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

John D Lambris, J. Lambris, G. Sfyroera, 2006, Molecular immunology.

Blocking Formation of the C3 Proconvertase and Lectin Pathways of Complement by Inhibits the Classical Staphylococcus Aureus the Extracellular Adherence Protein From

John D Lambris, J. Lambris, K. Ramyar, 2022 .

Blocking Formation of the C3 Proconvertase and Lectin Pathways of Complement by Inhibits the Classical Staphylococcus Aureus the Extracellular Adherence Protein From

John D Lambris, J. Lambris, K. Ramyar, 2022 .

Characterization of factor H-like molecules in rainbow trout

S. Franchini, J. Lambris, G. Sfyroera, 2000 .

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry.

Daniel Ricklin, John D Lambris, Yoshitomo Hamuro, 2008, Molecular immunology.

Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysine acetylation and mass spectrometry

John D Lambris, J. Lambris, Hui Chen, 2008, Journal of the American Society for Mass Spectrometry.

Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity

John D Lambris, G. Sfyroera, T. Mollnes, 2010, Innate immunity.

Rare Loss-of-Function Mutation in Complement Component C3 Provides Insight into Molecular and Pathophysiological Determinants of Complement Activity

John D Lambris, B. Nilsson, K. Ekdahl, 2015, The Journal of Immunology.