H. Zayed

H. Zayed, Mariem Sidenna, Tasnim Fadl, 2019, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach

H. Zayed, C. George Priya Doss, S. Udhaya Kumar, 2020, Frontiers in Genetics.

Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension

Hakeem G. Almabrazi, H. Zayed, A. Alsamman, 2022, Journal of personalized medicine.

Whole-exome sequencing analysis of NSCLC reveals the pathogenic missense variants from cancer-associated genes

S. R, H. Zayed, S. Younes, 2022, Comput. Biol. Medicine.

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

Abdul Quaiyoom Khan, H. Zayed, S. Uddin, 2019, Front. Oncol..

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes.

R. Roden, H. Zayed, S. Brendle, 2015, Vaccine.

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

L. Stamatatos, C. Schiffer, A. McGuire, 2017, Cell Reports.

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

H. Zayed, M. Raj, A. Ouhtit, 2017, Cell Communication and Signaling.

Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

T. D, G. C, H. Zayed, 2020, Molecules.

The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review

H. Zayed, S. Younes, M. Yassin, 2020, Expert review of hematology.

Structural modeling of p.V31F variant in the aspartoacylase gene

H. Zayed, N. Krishnamoorthy, 2016, Metabolic Brain Disease.

Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta‐analysis

R. El Bekay, H. Zayed, Akila G, 2018, Diabetes/metabolism research and reviews.

RNA splicing: a dual-edged sword for hepatocellular carcinoma

H. Zayed, M. Kashyap, D. Chandrashekar, 2022, Medical Oncology.

A Potential Link Between Oxidative Stress and Endothelial-to-Mesenchymal Transition in Systemic Sclerosis

A. Mangoni, H. Zayed, A. Eid, 2018, Front. Immunol..

A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease.

H. Zayed, C. George Priya Doss, R. Siva, 2021, Current opinion in pharmacology.

Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World

H. Zayed, C. Doss, F. Bakhsh, 2016, Scientific Reports.

RNA splicing: a dual-edged sword for hepatocellular carcinoma

H. Zayed, M. Kashyap, D. Chandrashekar, 2022, Medical Oncology.

Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.

H. Zayed, C. George Priya Doss, S. Udhaya Kumar, 2020, Advances in protein chemistry and structural biology.

A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

H. Zayed, C. George Priya Doss, A. Agrahari, 2018, Metabolic Brain Disease.

Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.

H. Zayed, C. George Priya Doss, D. Thirumal Kumar, 2019, Advances in protein chemistry and structural biology.

Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS)

H. Zayed, Zumin Shi, Jianghong Liu, 2020, Nutrients.

Fasting Ramadan During COVID-19 Pandemic: Immunomodulatory Effect

H. Zayed, Taghreed Abunada, Hanan Abunada, 2020, Frontiers in Nutrition.

Aberrant DNA methylation of PTPRG as one possible mechanism of its under‐expression in CML patients in the State of Qatar

L. Tomasello, Muthanna Samara, H. Zayed, 2020, Molecular genetics & genomic medicine.

Nasopharyngeal Expression of Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 in Children within SARS-CoV-2-Infected Family Clusters

H. Zayed, P. Tang, M. Hasan, 2021, Microbiology spectrum.

Rapid generation of stable cell lines expressing high levels of erythropoietin, factor VIII, and an antihuman CD20 antibody using lentiviral vectors.

H. Zayed, H. Spencer, C. Doering, 2013, Human gene therapy methods.

A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease

H. Zayed, C. George Priya Doss, D. Thirumal Kumar, 2018, Journal of cellular biochemistry.

In silico and in vivo models for Qatari‐specific classical homocystinuria as basis for development of novel therapies

Gheyath K Nasrallah, H. Blom, H. Zayed, 2018, Human mutation.

Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach

H. Zayed, C. George Priya Doss, R. Siva, 2018, Metabolic Brain Disease.

A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

H. Zayed, C. George Priya Doss, A. Agrahari, 2017, Metabolic Brain Disease.

Bladder neoplasms and NF-κB: an unfathomed association

H. Zayed, Thanka Johnson, George Priya Doss C, 2020, Expert review of molecular diagnostics.

Novel mutation in an Egyptian patient with infantile Canavan disease

H. Zayed, S. Mohamed, O. Zaki, 2016, Metabolic Brain Disease.

Clinical, biochemical, neuroradiological and molecular characterization of Egyptian patients with glutaric acidemia type 1

H. Zayed, Zumin Shi, S. Mohammad, 2019, Metabolic Brain Disease.

Tumor reversion: a dream or a reality

H. Zayed, M. Kashyap, A. Bharti, 2021, Biomarker research.

A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing

H. Zayed, S. Younes, C. Doss, 2021, 3 Biotech.

Genetic Epidemiology of Beta-Thalassemia in the Maldives: 23 years of a Beta-Thalassemia Screening Program.

F. Shebl, H. Zayed, N. Firdous, 2020, Gene.

Congenital diaphragmatic hernia and microtia in a newborn with mycophenolate mofetil (MMF) exposure: Phenocopy for Fryns syndrome or broad spectrum of teratogenic effects?

H. Zayed, A. Slavotinek, M. Parisi, 2009, American journal of medical genetics. Part A.

Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach

H. Zayed, C. George Priya Doss, A. Agrahari, 2018, Metabolic Brain Disease.

Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases.

Yoshihide Hayashizaki, Hideya Kawaji, Yasuhiro Murakawa, 2016, Trends in genetics : TIG.

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

Ikhlak Ahmed, M. Haris, S. Yadav, 2020, Molecular Cancer.

Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection

H. Zayed, C. Chakraborty, M. Bhattacharya, 2021, Frontiers in Immunology.

The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases

H. Zayed, H. Zedan, F. H. Ali, 2022, Chromosoma.

Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III

H. Zayed, R. Siva, S. Younes, 2021, Cell Biochemistry and Biophysics.

An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia

C. George Priya Doss, S Udhayakumar, D. Thirumal Kumar, 2020, Comput. Biol. Medicine.

Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach

H. Zayed, C. George Priya Doss, S. Udhaya Kumar, 2019, Journal of biomolecular structure & dynamics.

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer

Nikita Jain, C. George Priya Doss, D. Thirumal Kumar, 2019, Comput. Biol. Medicine.

Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar.

S. Kishore, H. Zayed, D. Trujillano, 2019, Gene.

Spectrum of mutations of familial hypercholesterolemia in the 22 Arab countries.

H. Zayed, Dalal Alhababi, 2018, Atherosclerosis.

miR-21 mimic blocks obesity in mice: A novel therapeutic option

R. El Bekay, H. Zayed, Adriana-Mariel Gentile, 2021, Molecular therapy. Nucleic acids.

miR-21 blocks obesity in mice: a potential therapy for humans

F. Tinahones, R. El Bekay, H. Zayed, 2020, medRxiv.

Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes.

H. Zayed, Sumaya Rahman, 2018, Gene.

A maternally inherited chromosome 18q22.1 deletion in a male with late‐presenting diaphragmatic hernia and microphthalmia–evaluation of DSEL as a candidate gene for the diaphragmatic defect

Allen D. Delaney, G. Shaw, A. Delaney, 2010, American journal of medical genetics. Part A.

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review

H. Zayed, D. Al-Sadeq, Taghreed Abunada, 2018, Respirology.

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer

H. Zayed, S. Uddin, M. Steinhoff, 2019, Cancers.

Non-coding RNAs as biomarkers of myocardial infarction.

H. Zayed, G. Pintus, R. Giordo, 2023, Clinica chimica acta; international journal of clinical chemistry.

Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.

R. Siva, Hatem Zayed, Ashish Kumar Agrahari, 2019, Journal of theoretical biology.

Assessment of lung cancer risk factors and mortality in Qatar: A case series study

Abdel-Salam G. Abdel-Salam, H. Zayed, Zumin Shi, 2020, Cancer reports.

Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review

H. Zayed, Shaza Malik, Sarah Okashah, 2021, Ophthalmic epidemiology.

Novel CD44-downstream signaling pathways mediating breast tumor invasion

H. Zayed, A. Ouhtit, M. M. Rahman, 2018, International journal of biological sciences.

Implications and theragnostic potentials of circular RNAs in rheumatic diseases.

H. Zayed, H. Ashour, H. Abdulkader, 2023, International journal of biological macromolecules.

The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach

Hatem Zayed, H. Zayed, 2020, Comput. Biol. Medicine.

Inositol 1,4,5-Trisphosphate Receptors in Hypertension

A. Arredouani, H. Zayed, A. Ouhtit, 2018, Front. Physiol..

Genetic variations associated with coronary artery disease and myocardial infarction in the Arab world: a systematic review and meta-analysis

H. Zayed, S. Younes, Zumin Shi, 2020, Highlights in BioScience.

Structural Determination o f the Broadly Reactive Anti-IGHV 169 Anti-idiotypic Antibody G 6 and Its Idiotope Graphical Abstract Highlights

L. Stamatatos, C. Schiffer, A. McGuire, 2017 .

Understanding the structure-function relationship of HPRT1 missense mutations in association with Lesch-Nyhan disease and HPRT1-related gout by in silico mutational analysis

Hatem Zayed, C. George Priya Doss, R. Siva, 2019, Comput. Biol. Medicine.

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery.

M. Kay, J. Tolar, H. Zayed, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review

H. Zayed, Gnanasambandan Ramanathan, Kaviyarasi Renu, 2023, Metabolites.

The Sleeping Beauty transposable element: evolution, regulation and genetic applications.

Hatem Zayed, Zoltán Ivics, Z. Izsvák, 2004, Current issues in molecular biology.

Krabbe Disease in the Arab World

H. Zayed, 2015, Journal of Pediatric Genetics.

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

Aamir Ahmad, Z. Nawaz, H. Zayed, 2020, Molecules.

miR‐20b, miR‐296, and Let‐7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes

F. Tinahones, M. Murri, R. El Bekay, 2018, Obesity.

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase.

H. Zayed, C. George Priya Doss, D. Thirumal Kumar, 2019, Advances in protein chemistry and structural biology.

Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review.

H. Zayed, N. Younes, 2019, Gene.

Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries

H. Zayed, S. Younes, M. Ahmad, 2021, Alzheimer disease and associated disorders.

Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations

H. Zayed, A. Eid, R. Iratni, 2023, Antioxidants.

Implication of salt stress induces changes in pigment production, antioxidant enzyme activity, and qRT-PCR expression of genes involved in the biosynthetic pathway of Bixa orellana L.

H. Zayed, C. Doss, S. Ramamoorthy, 2019, Functional & Integrative Genomics.

An integrative analysis to distinguish between emphysema (EML) and alpha-1 antitrypsin deficiency-related emphysema (ADL)-A systems biology approach.

H. Zayed, C. George Priya Doss, S. Udhaya Kumar, 2021, Advances in protein chemistry and structural biology.

A review of bioinformatics tools and web servers in different microarray platforms used in cancer research.

H. Zayed, C. George Priya Doss, S. Udhaya Kumar, 2022, Advances in protein chemistry and structural biology.

Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis.

H. Zayed, C. George Priya Doss, R. Siva, 2022, Advances in protein chemistry and structural biology.

Differences in the neovascular potential of thymus versus subcutaneous adipose‐derived stem cells from patients with myocardial ischaemia

F. Tinahones, R. El Bekay, H. Zayed, 2018, Journal of tissue engineering and regenerative medicine.

Protective Effect of Cyclically Pressurized Solid–Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death

Gheyath K Nasrallah, H. Zayed, D. Pagnozzi, 2018, Molecules.

Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis

F. Shebl, H. Zayed, C. Doss, 2018, Ophthalmic Research.

Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis.

H. Zayed, Haissam Abou-Saleh, U. Abdel-Motal, 2017, Diabetes research and clinical practice.

Unraveling the Dysbiosis of Vaginal Microbiome to Understand Cervical Cancer Disease Etiology—An Explainable AI Approach

H. Zayed, A. Alsamman, Achraf El Allali, 2023, Genes.

Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma

H. Zayed, A. Alsamman, K. Vasudevan, 2023, Frontiers in Medicine.

Comparison of potential inhibitors and targeting fat mass and obesity‐associated protein causing diabesity through docking and molecular dynamics strategies

H. Zayed, Gnanasambandan Ramanathan, George Priya Doss C, 2021, Journal of cellular biochemistry.

An updated overview of cyanidins for chemoprevention and cancer therapy.

J. Sharifi‐Rad, D. Calina, H. Zayed, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Evolving strategies and application of proteins and peptide therapeutics in cancer treatment.

H. Zayed, C. George Priya Doss, Kaviyarasi Renu, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies

H. Zayed, S. Younes, M. Qoronfleh, 2023, Hematology.

Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar.

Gheyath K Nasrallah, A. Al Haj Zen, Muthanna Samara, 2023, Molecular genetics & genomic medicine.

Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson’s and Gaucher diseases

H. Zayed, C. George Priya Doss, D. Thirumal Kumar, 2018, Metabolic Brain Disease.

Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma

H. Zayed, 2020, International journal of molecular sciences.

Bioinformatics investigation on blood-based gene expressions of Alzheimer's disease revealed ORAI2 gene biomarker susceptibility: An explainable artificial intelligence-based approach

H. Zayed, C. George Priya Doss, A. Alsamman, 2023, Metabolic Brain Disease.

An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD+ and Disulfiram

S. P, T. D, G. C, 2019, Journal of cellular biochemistry.

Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ).

H. Zayed, C. George Priya Doss, R. Siva, 2019, Advances in protein chemistry and structural biology.

A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.

H. Zayed, C. George Priya Doss, R. Siva, 2019, Advances in protein chemistry and structural biology.

Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene

R. El Bekay, H. Zayed, A. Ouhtit, 2017, Metabolic Brain Disease.

Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer

G. C, H. Zayed, M. Kashyap, 2023, Functional & Integrative Genomics.

Canavan disease: an Arab scenario.

H. Zayed, 2015, Gene.

CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin

H. Zayed, A. Fernando, R. Gaur, 2020, International journal of medical sciences.

Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease.

H. Zayed, C. George Priya Doss, I. Tayubi, 2023, Metabolic brain disease.

Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2

H. Zayed, T. Kumar D, Udhaya Kumar S, 2021, Frontiers in Molecular Biosciences.

Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2

H. Zayed, C. George Priya Doss, R. Siva, 2018, Metabolic Brain Disease.

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

H. Zayed, M. Raj, A. Ouhtit, 2017, Cell Communication and Signaling.

Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis.

H. Zayed, Zumin Shi, Hanan Abunada, 2019, Diabetes research and clinical practice.

A systemic approach to explore the mechanisms of drug resistance and altered signaling cascades in extensively drug-resistant tuberculosis.

H. Zayed, C. George Priya Doss, I. Tayubi, 2021, Advances in protein chemistry and structural biology.

A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation.

T. D, G. C, H. Zayed, 2023, Journal of biomolecular structure & dynamics.

Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature

H. Zayed, I. Gupta, A. Al Moustafa, 2023, Heliyon.

Structural modeling of p.V31F variant in the aspartoacylase gene

H. Zayed, N. Krishnamoorthy, 2016, Metabolic Brain Disease.

Single-cell transcriptomic analysis reveals crucial oncogenic signatures and its associative cell types involved in gastric cancer

H. Zayed, C. George Priya Doss, Achraf El Allali, 2023, Medical Oncology.

Potential Therapeutic Targets of Resveratrol in the Prevention and Treatment of Pulmonary Fibrosis.

H. Zayed, G. Pintus, R. Giordo, 2023, Frontiers in bioscience.

Genomic insights and advanced machine learning: characterizing autism spectrum disorder biomarkers and genetic interactions

H. Zayed, A. Alsamman, K. Sekaran, 2023, Metabolic brain disease.

microRNA 21 and long non-coding RNAs interplays underlie cancer pathophysiology: A narrative review

H. Zayed, R. Giordo, Fatemeh Abdullah M. Ahmadi, 2024, Non-coding RNA research.