K. Neet

发表

Mediation of Nerve Growth Factor-driven Cell Cycle Arrest in PC12 Cells by p53

T. Sladek, A. L. Hughes, L. Gollapudi, 2000, The Journal of Biological Chemistry.

Comparative equilibrium denaturation studies of the neurotrophins: nerve growth factor, brain-derived neurotrophic factor, neurotrophin 3, and neurotrophin 4/5.

K. Neet, D. Timm, P. D. de Haseth, 1994, Biochemistry.

Cooperativity in enzyme function: equilibrium and kinetic aspects.

K. Neet, 1980, Methods in enzymology.

Biophysical Characterization of Proteins in the Post-genomic Era of Proteomics*

J. Lee, K. Neet, Kenneth E Neet, 2002, Molecular & Cellular Proteomics.

Demonstration of a slow conformational change in liver glucokinase by fluorescence spectroscopy.

K. Neet, S X Lin, S. Lin, 1990, The Journal of biological chemistry.

Selectivity of Cell Signaling in the Neuronal Response Based on NGF Mutations and Peptidomimetics in the Treatment of Alzheimers Disease

K. Neet, Hrishikesh M. Mehta, S. Mahapatra, 2011 .

Construction of a mutated pro-nerve growth factor resistant to degradation and suitable for biophysical and cellular utilization

K. Neet, Promila Pagadala, L. A. Dvorak, 2006, Proceedings of the National Academy of Sciences.

Mutational studies of conserved residues in the dimer interface of nerve growth factor

K. Neet, S. Meyer, M. Guo, 1996, Protein science : a publication of the Protein Society.

Regulatory Properties of Glucokinase

P. Tippett, K. Neet, R. Keenan, 1988 .

An allosteric model for the inhibition of glucokinase by long chain acyl coenzyme A.

P. Tippett, K. Neet, 1982, The Journal of biological chemistry.

Subunit interactions of nerve growth factor: sedimentation analysis of the dissociation of the 7 S oligomer promoted by salt and ethylenediaminetetraacetate.

K. Neet, T. Palmer, 1980, Archives of biochemistry and biophysics.

Subunit interactions in 7S nerve growth factor. Gamma-esterase activity as a probe of the dissociation of the 7S oligomer promoted by salt and EDTA.

K. Neet, T. Palmer, 1980, The Journal of biological chemistry.

Subunit interactions of 7 S nerve growth factor. Gamma-esterase activity, rates, and conformational changes during reassociation.

K. Neet, A. G. Rao, 1984, The Journal of biological chemistry.

Characterization of the lectin from the bulbs of Eranthis hyemalis (winter aconite) as an inhibitor of protein synthesis.

K. Neet, M. A. Kumar, D. Timm, 1993, The Journal of biological chemistry.

pH-dependent effects of Cr(NH3)2ATP on kinetics of yeast hexokinase PII. Relationship to the slow transition mechanism.

K. Neet, B. Peters, 1976, The Journal of biological chemistry.

Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration.

P. Tippett, K. Neet, 1982, The Journal of biological chemistry.

The regulatory kinetic properties of porcine hepatic glucokinase

K. Neet, W. Vogel, R. Keenan, 1989, Molecular and Cellular Biochemistry.

Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation

K. Neet, H. Vaghefi, 2004, Oncogene.

The binding of zinc and copper ions to nerve growth factor is differentially affected by pH: implications for cerebral acidosis

R. Riopelle, K. Neet, S. Dostaler, 2001, Journal of neurochemistry.

Enzyme Catalytic Power Minireview Series*

K. Neet, Kenneth E. Neet, 1998, The Journal of Biological Chemistry.

TrkA Receptor “Hot Spots” for Binding of NT-3 as a Heterologous Ligand*

K. Neet, H. Saragovi, L. Ivanisevic, 2007, Journal of Biological Chemistry.

Hysteretic Enzymes, Slow Inhibition, Slow Activation, and Slow Membrane Binding

K. Neet, G. Ohning, N. R. Woodruff, 1984 .

Role of arginyl residues in yeast hexokinase PII.

K. Neet, C. L. Borders, K. L. Cipollo, 1978, Biochemistry.

Gene 5 protein of bacteriophage fd: a dimer which interacts co-operatively with DNA.

K. Neet, S. Cavalieri, D. Goldthwait, 1976, Journal of molecular biology.

Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant Δ9/13, which is selective for the p75 neurotrophin receptor

S. Lad, K. Neet, Allison L. Hughes, 2001, Journal of neuroscience research.

Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease.

E. Mufson, S. Lad, K. Neet, 2003, Current drug targets. CNS and neurological disorders.

Identification of Critical Residues within the Conserved and Specificity Patches of Nerve Growth Factor Leading to Survival or Differentiation*

K. Neet, Hrishikesh M. Mehta, S. Mahapatra, 2009, The Journal of Biological Chemistry.

Characterization of Histidine Residues Essential for Receptor Binding and Activity of Nerve Growth Factor*

K. Neet, S. Woo, 1996, The Journal of Biological Chemistry.

Hierarchical analysis of the nerve growth factor‐dependent and nerve growth factor‐independent differentiation signaling pathways in PC12 cells with protein kinase inhibitors

K. Neet, X. Campbell, 1995, Journal of neuroscience research.

A bryostatin-sensitive protein kinase C required for nerve growth factor activity.

K. Neet, A. Fields, K. R. Singh, 1994, Biochemistry.

Enzymes of pentose biosynthesis. The quaternary structure and reacting form of transketolase from baker's yeast.

K. Neet, H. Z. Sable, S. Cavaliere, 1975, Archives of biochemistry and biophysics.

The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src

T. Hunter, K. Neet, 1995, Molecular and cellular biology.

ProNGF mediates death of Natural Killer cells through activation of the p75NTR–sortilin complex

H. Muyderman, H. Zola, K. Neet, 2010, Journal of Neuroimmunology.

The lack of a role for protein kinase C in neurite extension and in the induction of ornithine decarboxylase by nerve growth factor in PC12 cells.

K. Neet, D. Reinhold, 1989, The Journal of biological chemistry.

During glaucoma, alpha2-macroglobulin accumulates in aqueous humor and binds to nerve growth factor, neutralizing neuroprotection.

K. Neet, H. Saragovi, Yu-jing Bai, 2011, Investigative ophthalmology & visual science.

Immunological determinants of nerve growth factor involved in p140trk (Trk) receptor binding

K. Neet, J. Nanduri, S. Vroegop, 1994, Journal of neuroscience research.

Studies on the quaternary structure of the threonine-sensitive aspartokinase-homoserine dehydrogenase of Escherichia coli. A proposed subunit-interaction model.

K. Neet, J. Mackall, 1974, European journal of biochemistry.

Stoichiometry of slow binding of palmitoyl-CoA to liver glucokinase.

K. Neet, W. Vogel, S. Lin, 2009, International journal of peptide and protein research.

Nerve Growth Factor Withdrawal-mediated Apoptosis in Naïve and Differentiated PC12 Cells through p53/Caspase-3-dependent and -independent Pathways*

K. Neet, H. Vaghefi, Allison L. Hughes, 2004, Journal of Biological Chemistry.

Proneurotrophins Require Endocytosis and Intracellular Proteolysis to Induce TrkA Activation*

P. Barker, K. Neet, C. Céni, 2008, Journal of Biological Chemistry.

Properties of thiol-subtilisin. The consequences of converting the active serine residue to cysteine in a serine protease.

D. Koshland, K. Neet, A. Nanci, 1968, The Journal of biological chemistry.

Interconversions between different sulfhydryl-related kinetic states in glucokinase.

P. Tippett, K. Neet, 1983, Archives of biochemistry and biophysics.

6-(p-toluidinyl)naphthalene-2-sulfonic acid as a fluorescent probe of yeast hexokinase: conformational states induced by sugar and nucleotide ligands.

K. Neet, G. Ohning, 1983, Biochemistry.

The cupric ion catalysis of the cleavage of gamma-globulin and other proteins by hydrogen peroxide.

K. Neet, F. Putnam, L. T. Lynn, 1961, The Journal of biological chemistry.

Activation of yeast hexokinase by chelators and the enzymic slow transition due to metal-nucleotide interactions.

K. Neet, W. Hueston, T. C. Furman, 1982, Archives of biochemistry and biophysics.

Electroporation-mediated gene delivery of cleavage-resistant pro–nerve growth factor causes retinal neuro- and vascular degeneration

K. Neet, M. Abdelsaid, S. Fagan, 2012, Molecular vision.

The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation".

D. Koshland, K. Neet, 1966, Proceedings of the National Academy of Sciences of the United States of America.

Regulatory kinetics of yeast hexokinase in situ.

K. Neet, L. Reitzer, 1974, Biochimica et biophysica acta.

CELL BIOLOGY

G. Hart, S. Woodson, R. Bradshaw, 2005 .

The catalytic and regulatory properties of enzymes.

D. Koshland, K. Neet, 1968, Annual review of biochemistry.

Sedimentation of chemically modified chymotrypsin.

K. Neet, S. Brydon, 1970, Archives of biochemistry and biophysics.

Yeast hexokinase PII. Conformational changes induced by substrates and substrate analogues.

K. Neet, B. Peters, 1978, The Journal of biological chemistry.

Transients and cooperativity. A slow transition model for relating transients and cooperative kinetics of enzymes.

K. Neet, G. Ainslie, J. Shill, 1972, The Journal of biological chemistry.

Effects of tunicamycin on NGF binding and neurite outgrowth in PC12 cells

K. Neet, T. J. Baribault, 1985, Journal of neuroscience research.

Cooperativity and slow transitions in the regulation of oligomeric and monomeric enzymes

K. Neet, G. Ainslie, 1976 .

Cooperativity in enzyme function: equilibrium and kinetic aspects.

K. Neet, 1995, Methods in enzymology.

[8] Hysteretic enzymes

K. Neet, G. Ainslie, 1980 .

Variation of the size of the reacting form of Escherichia coli K12 threonine-sensitive aspartokinase--homoserine dehydrogenase with pH and effectors.

K. Neet, J. Mackall, 1973, Biochemistry.

Quantitative assessment of the competitive binding of anionic ligands to albumin.

K. Neet, H. Meisner, J. Stair, 1980, Molecular pharmacology.

Cooperativity and the slow isomerization of δ-chymotrypsin

K. Neet, G. Ainslie, 1979, Molecular and Cellular Biochemistry.

Monomer-dimer equilibria of yeast hexokinase during reacting enzyme sedimentation.

K. Neet, B. Peters, J. Shill, 1974, Biochemistry.

Conformational stability of dimeric proteins: Quantitative studies by equilibrium denaturation

K. Neet, D. Timm, 1994, Protein science : a publication of the Protein Society.

Spectroscopic and chemical studies of the interaction between nerve growth factor (NGF) and the extracellular domain of the low affinity NGF receptor

K. Neet, A. Ross, D. Timm, 1992, Protein science : a publication of the Protein Society.

Equilibrium denaturation studies of mouse beta-nerve growth factor.

K. Neet, D. Timm, 1992, Protein science : a publication of the Protein Society.

Nerve growth factor and the concept of neural-epithelial interactions. Immunohistochemical observations in two cases of vasitis nodosa and six cases of prostatic adenocarcinoma.

K. Neet, K. Balogh, K. Deschryver‐Kecskemeti, 1987, Archives of pathology & laboratory medicine.

Observation of a kinetic slow transition in monomeric glucokinase.

P. Tippett, K. Neet, R. Keenan, 1990, Biochemistry.

Receptor binding, internalization, and retrograde transport of neurotrophic factors

R. Campenot, K. Neet, 2001, Cellular and Molecular Life Sciences CMLS.

Studies of the self-association of bacteriophage T4 gene 32 protein by equilibrium sedimentation.

R. Carroll, K. Neet, D. Goldthwait, 1975, Journal of molecular biology.

Subunit interactions of rabbit muscle aldolase. Conformational change of aldolase in magnesium chloride and its relationship to the dissociation of subunits.

K. Neet, L. Hsu, 1975, Journal of molecular biology.

Analysis of conformationally-linked dissociation of proteins.

K. Neet, 1974, Biophysical chemistry.

Subunit interactions of rabbit muscle aldolase. Dissociation of aldolase in 1.2 M magnesium chloride.

K. Neet, L. Hsu, 1973, Biochemistry.

The average molecular weight and shape of the “polymeric acids” found in Black Trona Water from the Green River Basin

K. Neet, J. F. Branthaver, R. E. Barden, 1984 .

Tumour necrosis factor‐alpha‐ vs. growth factor deprivation‐promoted cell death: different receptor requirements for mediating nerve growth factor‐promoted rescue

G. Taglialatela, K. Neet, T. Pappas, 2003, Aging cell.

Characterization of the recombinant extracellular domain of the neurotrophin receptor TrkA and its interaction with nerve growth factor (NGF)

K. Neet, S. Woo, C. Whalen, 1998, Protein science : a publication of the Protein Society.

Circular dichroism and crosslinking studies of the interaction between four neurotrophins and the extracellular domain of the low‐affinity neurotrophin receptor

K. Neet, A. Ross, D. Timm, 1994, Protein science : a publication of the Protein Society.

Alteration of NH-terminal Residues of Nerve Growth Factor Affects Activity and Trk Binding without Affecting Stability or Conformation (*)

K. Neet, D. Timm, S. Woo, 1995, The Journal of Biological Chemistry.

Relaxation spectra of yeast hexokinases. Isomerization of the enzyme.

J. Stuehr, K. Neet, J. Jentoft, 1977, Biochemistry.

Conformational changes and association of chemically modified chymotrypsins.

K. Neet, G. Ainslie, L. Barritt, 1974, Archives of biochemistry and biophysics.

The unprocessed C-terminal dipeptide of recombinant beta-nerve growth factor determines three stable forms with distinct biological activities.

Y. Luo, K. Neet, 1992, The Journal of biological chemistry.

A comparison of nerve growth factor binding protocols with native and mutant PC12 cells

K. Neet, M. Kasaian, 1990, Neurochemical Research.

Differences in the amino acid distributions of 310‐helices and α‐helices

M. E. Karpen, K. Neet, Mary E. Karpen, 1992 .

A TrkA-selective, Fast Internalizing Nerve Growth Factor-Antibody Complex Induces Trophic but Not Neuritogenic Signals*

A. Cuello, K. Neet, A. Kamen, 1998, The Journal of Biological Chemistry.

Individual and Combined Effects of TrkA and p75NTR Nerve Growth Factor Receptors

R. Bradshaw, S. Lad, K. Neet, 2003, Journal of Biological Chemistry.

Comparison of nerve growth factor receptor binding models using heterodimeric muteins

K. Neet, Hrishikesh M. Mehta, H. Mehta, 2012, Journal of neuroscience research.

Comparing short protein substructures by a method based on backbone torsion angles

M. E. Karpen, K. Neet, K E Neet, 1989, Proteins.

Hysteretic enzymes.

K. Neet, G. Ainslie, 1980, Methods in enzymology.

Differences in salicylic acid glucose conjugations by UGT74F1 and UGT74F2 from Arabidopsis thaliana

K. Neet, J. Dean, C. V. Iancu, 2017, Scientific Reports.

A slow transient kinetic process of yeast hexokinase.

K. Neet, J. Shill, 1971, The Biochemical journal.

The isolation of a dimer of gene 8 protein of bacteriophage fd.

K. Neet, S. Cavalieri, D. Goldthwait, 1976, Journal of molecular biology.

A common pentapeptide conformation occurs in viral acid proteases and other proteins.

M. E. Karpen, K. Neet, P. de Haseth, 1990, Journal of molecular biology.

Curare-binding macromolecules from medullated nerve tissue.

K. Neet, S. Friess, 1962, Archives of biochemistry and biophysics.

Pyruvate carboxylase: inactivation by sulfhydryl-group reagents in the presence of certain inorganic anions, substrates, and modifiers and the effects on the allosteric properties of the enzyme.

K. Neet, E. Palacián, 1972, Biochimica et biophysica acta.

Inhibition of biological activity of mouse beta-nerve growth factor by monoclonal antibody.

K. Neet, M. Fanger, S. L. Warren, 1980, Science.

Ligand-Dependent TrkA Activity in Brain Differentially Affects Spatial Learning and Long-Term Memory

X. Tong, E. Hamel, K. Neet, 2011, Molecular Pharmacology.

Trophic regulation of nodose ganglion cell development: Evidence for an expanded role of nerve growth factor during embryogenesis in the rat

K. Neet, D. Katz, R. Lillis, 1990, Experimental Neurology.

Individual and Combined Effects of TrkA and p75 Nerve Growth Factor Receptors A ROLE FOR THE HIGH AFFINITY RECEPTOR SITE*

D. Peterson, R. Bradshaw, S. Lad, 2003 .

Self-association of Gene 32 Protein

R. Carroll, K. Neet, D. Goldthwait, 1973 .

Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors*

K. Neet, M. Ioannou, S. Allen, 2009, The Journal of Biological Chemistry.

Self-association of gene-32 protein of bacteriophage T4.

R. Carroll, K. Neet, D. Goldthwait, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine

L. Gollapudi, K. Neet, 1997, Journal of neuroscience research.

Chronic and Acute Models of Retinal Neurodegeneration TrkA Activity Are Neuroprotective whereas p75NTR Activity Is Neurotoxic through a Paracrine Mechanism*

Jing Xu, Marinko V. Sarunic, Yujing Bai, 2010, The Journal of Biological Chemistry.

Threonine inhibition of the aspartokinase--homoserine dehydrogenase I of Escherichia coli. Threonine binding studies.

K. Neet, C. Bearer, 1978, Biochemistry.

Threonine inhibition of the aspartokinase--homoserine dehydrogenase I of Escherichia coli. A slow transient and cooperativity of inhibition of the aspartokinase activity.

K. Neet, C. Bearer, 1978, Biochemistry.

Threonine inhibition of the aspartokinase--homoserine dehydrogenase I of Escherichia coli. Stopped-flow kinetics and the cooperativity of inhibition of the homoserine dehydrogenase activity.

K. Neet, C. Bearer, 1978, Biochemistry.

Nerve growth factor in human amniotic and cerebrospinal fluid.

K. Neet, M. Kasaian, 1989, BioFactors.

Regulatory properties of yeast hexokinase PII. Metal specificity, nucleotide specificity, and buffer effects.

K. Neet, B. Peters, 1977, The Journal of biological chemistry.

Beta nerve growth factor binding to PC12 cells. Association kinetics and cooperative interactions.

K. Neet, N. R. Woodruff, 1986, Biochemistry.

[16] Derivation of monoclonal antibody to nerve growth factor

K. Neet, M. Fanger, T. J. Baribault, 1987 .

Activation of the mitogen‐activated protein kinase pathway through p75NTR: A common mechanism for the neurotrophin family

S. Lad, K. Neet, Kenneth E. Neet, 2003, Journal of neuroscience research.

Internalization of nerve growth factor by PC12 cells. A description of cellular pools.

K. Neet, M. Kasaian, 1988, The Journal of biological chemistry.

Expression of the cDNA for mouse beta-nerve growth factor protein in Escherichia coli.

K. Neet, G. Hu, 1988, Gene.

Ligand-dependent TrkA activity in brain impacts differently on spatial learning and long-term memory

X. Tong, E. Hamel, K. Neet, 2011 .

Differences in the amino acid distributions of 3(10)-helices and alpha-helices.

M. E. Karpen, K. Neet, P. de Haseth, 1992, Protein science : a publication of the Protein Society.

Inhibition of beta nerve growth factor binding to PC12 cells by alpha nerve growth factor and gamma nerve growth factor.

K. Neet, N. R. Woodruff, 1986, Biochemistry.

Modulation of the neuronal binding of the β subunit of nerve growth factor (NGF) by the α‐NGF subunit

K. Neet, N. R. Woodruff, 1982 .

Alzheimer's Disease and Related Disorders

K. Neet, S. I. Harik, 1990, Neurology.

Ligand-Dependent TrkA Activity in Brain Differentially Affects Spatial Learning and Long-Term Memory

X. Tong, E. Hamel, K. Neet, 2011, Molecular Pharmacology.

Kinetics of the cooperativity of the Ca2+-transporting adenosine triphosphatase of sarcoplasmic reticulum and the mechanism of the ATP interaction.

N. Green, K. Neet, 1977, Archives of biochemistry and biophysics.

Demonstration of a slow conformational change in liver glucokinase by fluorescence spectroscopy.

K. Neet, S X Lin, 1990, The Journal of biological chemistry.