H. Fukumoto

发表

The C-terminal domain of p53 catalyzes DNA-renaturation and strand exchange toward annealing between intact ssDNAs and toward eliminating damaged ssDNA from duplex formation through preferential recognition of damaged DNA by a duocarmycin.

N. Saijo, T. Terada, H. Yokote, 1998, Mutation research.

Mechanisms of Action of the Novel Sulfonamide Anticancer Agent E7070 on Cell Cycle Progression in Human Non-Small Cell Lung Cancer Cells

J. Usuda, N. Saijo, K. Nishio, 2004, Investigational New Drugs.

Mechanism of action of aragusterol a (YTA0040), a potent anti‐tumor marine steroid targeting the G1 phase of the cell cycle

N. Saijo, T. Yoneda, T. Yamagishi, 2000, International journal of cancer.

Osteopontin induces angiogenesis of murine neuroblastoma cells in mice

N. Saijo, Y. Ohe, K. Nishio, 2002, International journal of cancer.

Interferon‐γ‐inducing Factor Gene Transfection into Lewis Lung Carcinoma Cells Reduces Tumorigenicity in vivo

N. Saijo, Y. Ohe, K. Nishio, 1997, Japanese journal of cancer research : Gann.

Genetic immunotherapy by intrapleural, intraperitoneal and subcutaneous injection of IL‐2 gene‐modified Lewis lung carcinoma cells

T. Ohira, N. Saijo, Y. Ohe, 1997, International journal of cancer.

Decreased Expression of α2,8 Sialyltransferase and Increased Expression of β1,4 N-Acetylgalactosaminyltransferase in Gastrointestinal Cancers

N. Saijo, K. Nishio, H. Fukumoto, 2002 .

Reversal of adriamycin resistance with chimeric anti‐ganglioside GM2 antibody

N. Saijo, K. Nishio, H. Fukumoto, 1996, International journal of cancer.

Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells.

J. Usuda, N. Saijo, K. Nishio, 2001, Lung cancer.

Antitumor effects of butyrolactone I, a selective cdc2 kinase inhibitor, on human lung cancer cell lines.

N. Saijo, H. Yokote, K. Nishio, 1996, Anticancer research.

Mechanism of vinorelbine-induced radiosensitization of human small cell lung cancer cells

J. Usuda, N. Saijo, K. Nishio, 2002, Cancer Chemotherapy and Pharmacology.

Drug resistance in lung cancer.

N. Saijo, K. Nishio, H. Fukumoto, 1999, Current opinion in oncology.

Enhanced Anti‐tumor Effect of Trastuzumab in Combination with Cisplatin

N. Saijo, K. Nishio, H. Fukumoto, 2002, Japanese journal of cancer research : Gann.

A Topoisomerase II Inhibitor, NK109, Induces DNA Single‐ and Double‐strand Breaks and Apoptosis

N. Saijo, K. Nishio, H. Arioka, 1996, Japanese journal of cancer research : Gann.

Deletional mutant EGFR detected in circulating tumor-derived DNA from lung cancer patients treated with gefitinib.

K. Nishio, H. Fukumoto, T. Tamura, 2005 .

Effect of Glutathione Depletion on Cisplatin Resistance in Cancer Cells Transfected with the γ‐Glutamylcysteine Synthetase Gene

N. Saijo, H. Yokote, K. Nishio, 1997, Japanese journal of cancer research : Gann.

Anti-tumour activities of a new benzo[c]phenanthridine agent, 2,3-(methylenedioxy)-5-methyl-7-hydroxy-8-methoxybenzo[c]phena nthridini um hydrogensulphate dihydrate (NK109), against several drug-resistant human tumour cell lines.

N. Saijo, K. Nishio, H. Kurokawa, 1997, British Journal of Cancer.

Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.

N. Saijo, K. Nishio, H. Kurokawa, 1999, Oncology reports.

Proximal 5'-flanking sequence of the human gamma-glutamylcysteine synthetase heavy subunit gene is involved in cisplatin-induced transcriptional up-regulation in a lung cancer cell line SBC-3.

J. Usuda, N. Saijo, K. Nishio, 1997, Biochemical and biophysical research communications.

Identification ofcis-Acting DNA Elements of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene

N. Saijo, K. Nishio, H. Arioka, 1997 .

In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction.

N. Saijo, K. Nishio, H. Fukumoto, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Characterization of C6‐10A glioma cells highly responsive to β‐adrenergic receptor agonist‐induced NGF synthesis/secretion

H. Fukumoto, H. Fukumoto, M. Kakihana, 1994, Glia.

Restoration of p53 gene function in 12-O-tetradecanoylphorbor 13-acetate-resistant human leukemia K562/TPA cells.

J. Usuda, H. Kato, N. Saijo, 2003, International journal of oncology.

Preferential Binding of E7010 to Murine β3‐Tubulin and Decreased β3‐Tubulin in E7010‐resistant Cell Lines

N. Saijo, K. Nishio, H. Fukumoto, 1998, Japanese journal of cancer research : Gann.

Molecular determinants of UCN‐01‐induced growth inhibition in human lung cancer cells

J. Usuda, H. Kato, N. Saijo, 2000, International journal of cancer.

Activation-Induced Apoptosis of Peripheral Lymphocytes Treated with 7-Hydroxystaurosporine, UCN-01

J. Usuda, N. Saijo, Y. Ohe, 1999, Investigational New Drugs.

Ectopic p16ink4 expression enhances CPT‐11‐induced apoptosis through increased delay in S‐phase progression in human non‐small‐cell‐lung‐cancer cells

J. Usuda, N. Saijo, K. Nishio, 2000 .

Gamma-glutamylcysteine synthetase gene overexpression results in increased activity of the ATP-dependent glutathione S-conjugate export pump and cisplatin resistance.

N. Saijo, K. Nishio, H. Arioka, 1995, Biochemical and biophysical research communications.

Differentiation of erythroid progenitor (CFU-E) cells from mouse fetal liver cells and murine erythroleukemia (TSA8) cells without proliferation

M. Obinata, Y. Mishina, H. Fukumoto, 1988, Molecular and cellular biology.

Effect of a chimeric anti‐ganglioside GM2 antibody on ganglioside GM2‐expressing human solid tumors In vivo

N. Saijo, Y. Ohe, K. Fukuoka, 1999, International journal of cancer.

p16INK4 Expression Is Associated with the Increased Sensitivity of Human Non‐small Cell Lung Cancer Cells to DNA Topoisomerase I Inhibitors

J. Yokota, N. Saijo, H. Yokote, 1997, Japanese journal of cancer research : Gann.

Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer

S. Hirohashi, T. Ochiya, K. Nishio, 2005, Cancer science.

Antitumor activity of the selective epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) Iressa® (ZD1839) in an EGFR‐expressing multidrug‐resistant cell line in vitro and in vivo

N. Saijo, M. Mori, K. Nishio, 2002, International journal of cancer.

Mechanism of erythropoietin action on the erythroid progenitor cells induced from murine erythroleukemia cells (TSA8).

Y. Matsui, M. Obinata, H. Fukumoto, 1989, Development.

Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1‐Phenylpropenone Derivative, AM‐132, by Tumor Necrosis Factor‐cc or Interleukin‐6

N. Saijo, Y. Ohe, K. Nishio, 2001, Japanese journal of cancer research : Gann.

Different signalling pathways are used in the commitment of murine erythroleukemia cells (TSA8) to differentiate, and in the erythropoietin action on progenitor cells.

Y. Matsui, M. Obinata, H. Fukumoto, 1989, Cell structure and function.

Factors controlling induction of commitment of murine erythroleukemia (TSA8) cells to CFU-E (colony forming unit-erythroid).

M. Obinata, Y. Mishina, H. Fukumoto, 1987, Development.

Enhanced interaction between tubulin and microtubule‐associated protein 2 via inhibition of MAP kinase and CDC2 kinase by paclitaxel

N. Saijo, H. Arioka, H. Kurokawa, 1995, International journal of cancer.

Small In-Frame Deletion in the Epidermal Growth Factor Receptor as a Target for ZD6474

N. Saijo, K. Nishio, H. Fukumoto, 2004, Cancer Research.

Decreased expression of alpha2,8 sialyltransferase and increased expression of beta1,4 N-acetylgalactosaminyltransferase in gastrointestinal cancers.

N. Saijo, K. Nishio, H. Fukumoto, 2002, Experimental biology and medicine.

Enhancement of Cisplatin Sensitivity in High Mobility Group 2 cDNA‐transfected Human Lung Cancer Cells

Kazuya Fukuoka, N. Saijo, H. Yokote, 1999, Japanese journal of cancer research : Gann.

Detailed characterization of the biological activities of recombinant human nerve growth factor expressed in Chinese hamster ovary cells.

H. Fukumoto, K. Kato, M. Kakihana, 1993, Molecular and chemical neuropathology.

Phorbol ester and okadaic acid-resistant cells: the crossroads of signal transduction and drug resistance.

N. Saijo, K. Nishio, H. Arioka, 1995, The American journal of medicine.

Effects of different combinations of gefitinib and irinotecan in lung cancer cell lines expressing wild or deletional EGFR.

N. Saijo, K. Kiura, M. Tanimoto, 2006, Lung cancer.

Mitogen-activated protein kinase antisense oligonucleotide inhibits the growth of human lung cancer cells.

J. Usuda, N. Saijo, K. Nishio, 1999, International journal of oncology.