D. Powell

L. Giudice, C. Conover, D. Powell, 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Structural and biological characterization of bovine insulin-like growth factor binding protein-3.

C. Conover, D. Powell, M. Ronk, 1990, Endocrinology.

Adult Tph2 knockout mice without brain serotonin have moderately elevated spine trabecular bone but moderately low cortical bone thickness.

D. Powell, R. Brommage, Jeff Liu, 2015, BoneKEy reports.

Reply to Lrp5 regulation of bone mass and gut serotonin synthesis

A. Robling, P. López-Casas, M. Warman, 2014, Nature Medicine.

The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells

S. Lewin, D. Powell, P. Cameron, 2015, Retrovirology.

Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption

P. Lapuerta, D. Powell, B. Zambrowicz, 2019, The Journal of clinical endocrinology and metabolism.

The Impact of Sotagliflozin on Renal Function, Albuminuria, Blood Pressure, and Hematocrit in Adults With Type 1 Diabetes

H. Heerspink, D. Powell, F. Persson, 2019, Diabetes Care.

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.

Richard K P Benninger, David W Piston, David R Powell, 2009, The Biochemical journal.

Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.

J. K. Oeser, R. O’Brien, A. Ustione, 2016, Endocrinology.

Identification of a distal regulatory sequence of the human IGFBP-1 gene promoter and regulation by the progesterone receptor in a human endometrial adenocarcinoma cell line.

D. Powell, J. Gao, L. Tseng, 1994, DNA and cell biology.

Improved glycemic control in mice lacking Sglt1 and Sglt2.

F. Mseeh, Z. Ding, D. Powell, 2013, American journal of physiology. Endocrinology and metabolism.

Perturbations in Bone Formation and Resorption in Insulin‐Like Growth Factor Binding Protein‐3 Transgenic Mice

D. Powell, C. Rosen, R. Turner, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dentin Dysplasia in Notum Knockout Mice

D. Powell, G. Hansen, B. Zambrowicz, 2016, Veterinary pathology.

Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation

S. Mohan, K. Lau, D. Powell, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.

C. Conover, D. Powell, L. Bale, 2011, Endocrinology.

LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2

D. Powell, A. Suwanichkul, B. Zambrowicz, 2011, Obesity.

FKHR binds the insulin response element in the insulin-like growth factor binding protein-1 promoter.

D. Yee, J. Jackson, D. Powell, 1999, Endocrinology.

Effect of LX 4211 on Glucose Homeostasis and Body Composition in Preclinical Models s

Alan G. E. Wilson, F. Mseeh, Z. Ding, 2014 .

Expression of the insulin like growth factor-binding protein 3 (IGFBP-3) gene is increased in human renal carcinomas.

D. Powell, G. Jakse, P. Petrides, 1991, The Journal of urology.

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice

E. Wright, V. Kepe, J. Barrio, 2016, The Journal of physiology.

Serum somatomedin levels in adults with chronic renal failure: the importance of measuring insulin-like growth factor I (IGF-I) and IGF-II in acid-chromatographed uremic serum.

D. Powell, F. Liu, R. Hintz, 1986, The Journal of clinical endocrinology and metabolism.

Serum concentrations of insulin-like growth factor (IGF)-1, IGF-2 and unsaturated somatomedin carrier proteins in children with chronic renal failure.

D. Powell, R. Hintz, R. Rosenfeld, 1987, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Germ line knockout of IGFBP-3 reveals influences of the gene on mammary gland neoplasia

D. Powell, M. Pollak, E. Birman, 2015, Breast Cancer Research and Treatment.

Conservation of IGFBP structure during evolution: cloning of chicken insulin-like growth factor binding protein-5.

H. Luthman, D. Powell, S. Allander, 1995, Progress in growth factor research.

The heparin binding domain of insulin-like growth factor binding protein (IGFBP)-3 increases susceptibility of IGFBP-3 to proteolysis.

D. Powell, P. Campbell, S. Durham, 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Insulin-like growth factor (IGF)-binding protein-3 blocks IGF-I-induced receptor down-regulation and cell desensitization in cultured bovine fibroblasts.

C. Conover, D. Powell, C. A. Conover, 1991, Endocrinology.

Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice

Z. Ding, D. Powell, G. Hansen, 2020, Veterinary pathology.

Insulin-like growth factor (IGF) suppression of IGFBP-1 production: evidence for mediation by the type I IGF receptor

D. Powell, A. Suwanichkul, S. L. Morris, 1993, Regulatory Peptides.

Decreased Hepatic Insulin-Like Growth Factor (IGF)-I and Increased IGF Binding Protein-1 and -2 Gene Expression in Experimental Uremia.

D. Powell, R. Baxter, S. Durham, 1997, Endocrinology.

LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2015, Pharmacology research & perspectives.

Sotagliflozin improves glycemic control in nonobese diabetes-prone mice with type 1 diabetes

Z. Ding, D. Powell, A. Sands, 2015, Diabetes, metabolic syndrome and obesity : targets and therapy.

The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro.

D. Powell, J. Shively, W. Burch, 1990, The Journal of clinical endocrinology and metabolism.

HNF1 activates transcription of the human gene for insulin-like growth factor binding protein-1.

D. Powell, A. Suwanichkul, 1993, DNA and cell biology.

Effect of chronic renal failure and growth hormone therapy on the insulin-like growth factors and their binding proteins

D. Powell, S. Durham, A. Suwanichkul, 2000, Pediatric Nephrology.

Identification of an insulin-responsive element in the promoter of the human gene for insulin-like growth factor binding protein-1.

D. Powell, S. L. Morris, A. Suwanickul, 1993, The Journal of biological chemistry.

Effects of grwoth hormone therapy and malnutrition on the growth of rats with renal failure

D. Powell, R. Hintz, R. Rosenfeld, 1988, Pediatric Nephrology.

Immunoblot studies of the IGF-related acid-labile subunit.

D. Powell, F. Liu, R. Hintz, 1994, The Journal of clinical endocrinology and metabolism.

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.

H. Koepsell, D. Powell, T. Masuda, 2014, American journal of physiology. Renal physiology.

Effects of LX4211, a dual sodium-dependent glucose cotransporters 1 and 2 inhibitor, on postprandial glucose, insulin, glucagon-like peptide 1, and peptide tyrosine tyrosine in a dose-timing study in healthy subjects.

D. Powell, A. Sands, B. Zambrowicz, 2013, Clinical therapeutics.

Insulin-like Growth Factor Binding Proteins from Cultured Human Fibroblasts

C. Conover, D. Powell, F. Liu, 2013 .

Characterization of insulin-like growth factors and their binding proteins in peritoneal dialysate

D. Powell, S. Durham, Phillip D. K. Lee, 1996, Pediatric Nephrology.

Characterization of Insulin-Like Growth Factor Binding Protein-3 in Chronic Renal Failure Serum

D. Powell, F. Liu, C. Belsha, 1993, Pediatric Research.

Structure of the human chromosomal gene for the 25 kilodalton insulin-like growth factor binding protein.

D. Powell, A. Suwanichkul, M. Cubbage, 1989, Molecular endocrinology.

Study Design and Rationale of a Dose‐Ranging Trial of LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy

P. Lapuerta, J. Rosenstock, W. Cefalu, 2013, Clinical cardiology.

Antiserum developed for the E peptide region of insulin-like growth factor IA prohormone recognizes a serum protein by both immunoblot and radioimmunoassay.

D. Powell, F. Liu, R. Hintz, 1987, The Journal of clinical endocrinology and metabolism.

Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice

Z. Ding, D. Powell, G. Hansen, 2015, Front. Endocrinol..

Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3',5'-cyclic adenosine monophosphate is additive in HepG2 cells.

L. Giudice, F. Kaper, A. Giaccia, 2000, The Journal of clinical endocrinology and metabolism.

Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1

C. Conover, D. Powell, Phillip D. K. Lee, 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Kinetics of insulin-like growth factor (IGF) and IGF-binding protein responses to a single dose of growth hormone.

D. Powell, J. Guevara-Aguirre, S. Durham, 1997, The Journal of clinical endocrinology and metabolism.

Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity

D. Powell, C. Kesavan, C. Rundle, 2022, bioRxiv.

The insulin-like growth factor axis and growth in children with chronic renal failure: a report of the Southwest Pediatric Nephrology Study Group.

D. Powell, P. Campbell, R. Hogg, 1998, The Journal of clinical endocrinology and metabolism.

The insulin-like growth factor axis and growth in children with chronic renal failure

D. Powell, P. Campbell, R. Hogg, 1998 .

Characterization of insulin-like growth factor-binding proteins in human serum from patients with chronic renal failure.

D. Powell, F. Liu, R. Hintz, 1990, The Journal of clinical endocrinology and metabolism.

Bioactivity of a 29-Kilodalton Insulin-Like Growth Factor Binding Protein-3 Fragment Present in Excess in Chronic Renal Failure Serum

S. Mohan, C. Conover, D. Powell, 1997, Pediatric Research.

Insulin-like growth factor (IGF) binding protein-3 potentiation of IGF action is mediated through the phosphatidylinositol-3-kinase pathway and is associated with alteration in protein kinase B/AKT sensitivity.

C. Conover, D. Powell, S. Durham, 2000, Endocrinology.

Modulation of growth factors by growth hormone in children with chronic renal failure. The Southwest Pediatric Nephrology Study Group.

J. Frane, D. Powell, R. Hogg, 1997, Kidney international.

Method for purification of an insulin-like growth factor-binding protein produced by human HEP G2 hepatoma cells.

D. Powell, J. Shively, R. Hintz, 1987, Journal of chromatography.

IGF Binding Proteins in Growth-Retarded Children with Chronic Renal Failure

D. Powell, R. Baxter, Phillip D. K. Lee, 1989, Pediatric Research.

C. Conover, D. Powell, S. Durham, 2000, Endocrinology.

Dexamethasone stimulates expression of insulin-like growth factor binding protein-1 in HEP G2 human hepatoma cells.

D. Powell, A. Suwanichkul, S. L. Morris, 1993, Growth regulation.

Regulation of insulin-like growth factor-binding protein (IGFBP) expression by breast cancer cells: use of IGFBP-1 as an inhibitor of insulin-like growth factor action.

D. Yee, J. Jackson, D. Powell, 1992, Journal of the National Cancer Institute.

Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor.

D. Yee, N. Rosen, D. Powell, 1990, The Journal of clinical investigation.

High‐throughput Screening of Mouse Knockout Lines Identifies True Lean and Obese Phenotypes

D. Powell, A. Sands, A. Suwanichkul, 2008, Obesity.

Saturation Screening of the Druggable Mammalian Genome

R. Ramirez-Solis, D. Powell, F. Kern, 2005 .

Metabolic, Intestinal, and Cardiovascular Effects of Sotagliflozin Compared With Empagliflozin in Patients With Type 2 Diabetes: A Randomized, Double-Blind Study

E. Ferrannini, D. Powell, P. Banks, 2022, Diabetes care.

Deletion of the Gene Encoding the Ubiquitously Expressed Glucose-6-phosphatase Catalytic Subunit-related Protein (UGRP)/Glucose-6-phosphatase Catalytic Subunit-β Results in Lowered Plasma Cholesterol and Elevated Glucagon*

J. K. Oeser, R. O’Brien, O. McGuinness, 2006, Journal of Biological Chemistry.

Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice.

D. Powell, S. Durham, A. Suwanichkul, 2001, Endocrinology.

Overexpression of the acid-labile subunit of the IGF ternary complex in transgenic mice.

D. Powell, S. Durham, A. Suwanichkul, 2001, Endocrinology.

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors.

Alan G. E. Wilson, Giovanni Cianchetta, Z. Ding, 2009, Bioorganic & medicinal chemistry letters.

Identification of a promoter element which participates in cAMP-stimulated expression of human insulin-like growth factor-binding protein-1.

D. Powell, A. Suwanichkul, P. D. Lee, 1993, The Journal of biological chemistry.

Effects of renal failure on the growth hormone-insulin-like growth factor axis.

D. Powell, 1997, The Journal of pediatrics.

Structure and chromosomal localization of human insulin-like growth factor-binding protein genes.

C. Larsson, H. Luthman, D. Powell, 1993, Growth regulation.

Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome.

Alan G. E. Wilson, S. D. Kimball, D. Powell, 2015, Bioorganic & medicinal chemistry letters.

Insulin-like growth factor binding proteins from cultured human fibroblasts. Characterization and hormonal regulation.

C. Conover, D. Powell, F. Liu, 1989, The Journal of clinical investigation.

Purification of the insulin-like growth factor II (IGF-II) receptor from an IGF-II-producing cell line, and generation of an antibody which both immunoprecipitates and blocks the type 2 IGF receptor.

D. Powell, R. Rosenfeld, P. D. Lee, 1986, Biochemical and biophysical research communications.

Regulation of insulin-like growth factor-binding protein messenger ribonucleic acid levels in sheep thyroid cells.

L. Bachrach, D. Powell, F. Liu, 1991, Endocrinology.

Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children: a report of the Southwest Pediatric Nephrology Study Group.

S. Mohan, J. Frane, D. Powell, 1999, The Journal of clinical endocrinology and metabolism.

Insulin-like growth factor-binding protein-6 levels are elevated in serum of children with chronic renal failure: a report of the Southwest Pediatric Nephrology Study Group.

J. Frane, D. Powell, R. Hogg, 1997, The Journal of clinical endocrinology and metabolism.

Plasminogen binds the heparin-binding domain of insulin-like growth factor-binding protein-3.

D. Powell, P. Campbell, S. Durham, 1998, American journal of physiology. Endocrinology and metabolism.

Lrp5 functions in bone to regulate bone mass

F. Mseeh, A. Robling, M. Warman, 2011, Nature Medicine.

Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque

Z. Ding, D. Powell, G. Hansen, 2016, Diabetes, metabolic syndrome and obesity : targets and therapy.

Direct Functional Interactions between Insulin-like Growth Factor-binding Protein-3 and Retinoid X Receptor-α Regulate Transcriptional Signaling and Apoptosis*

J. Clifford, J. Kurie, P. Cohen, 2000, The Journal of Biological Chemistry.

Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2009, Journal of medicinal chemistry.

Insulin-like growth factors (IGFs) and IGF-binding proteins in the developing rhesus monkey.

D. Styne, D. Powell, F. Liu, 1991, The Journal of clinical endocrinology and metabolism.

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

Alan G. E. Wilson, D. Powell, A. Sands, 2008, Journal of Pharmacology and Experimental Therapeutics.

Direct control of the Forkhead transcription factor AFX by protein kinase B

Geert J. P. L. Kops, David R. Powell, J. Bos, 1999, Nature.

High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes

Z. Ding, D. Powell, A. Sands, 2021, Diabetes, metabolic syndrome and obesity : targets and therapy.

Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity

Z. Ding, D. Powell, G. Hansen, 2020, Diabetes, metabolic syndrome and obesity : targets and therapy.

Analysis of Candidate Genes for Susceptibility to Type I Diabetes: A Case-Control and Family-Association Study of Genes on Chromosome 2q31–35

M. Tsai, D. Powell, F. Naya, 1997, Diabetes.

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

D. Barford, S. O’Rahilly, N. Wareham, 2013, Cell.

Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4.

G. Semenza, D. Powell, P. Scherer, 2013, American journal of respiratory and critical care medicine.

Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1.

D. Powell, A. Suwanichkul, Phillip D. K. Lee, 1991, The Journal of biological chemistry.

Rapid development of glomerular injury and renal failure in mice lacking p53R2

D. Powell, Zheng-zheng Shi, G. Hansen, 2005, Pediatric Nephrology.

Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity.

D. Powell, A. Suwanichkul, M. Cubbage, 1990, The Journal of biological chemistry.

Characterization of proinsulin-like growth factor-II E-region immunoreactivity in serum and other biological fluids.

D. Powell, F. Liu, R. Hintz, 1993, The Journal of clinical endocrinology and metabolism.

The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells.

D. Yee, R. Lupu, R. Dickson, 1989, Biochemical and biophysical research communications.

Multiple proteins bind the insulin response element in the human IGFBP-1 promoter.

D. Powell, S. Durham, A. Suwanichkul, 1995, Progress in growth factor research.

Chicken insulin-like growth factor binding protein (IGFBP)-5: conservation of IGFBP-5 structure and expression during evolution.

H. Luthman, D. Powell, S. Allander, 1997, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Contiguous localization of the genes encoding human insulin-like growth factor binding proteins 1 (IGBP1) and 3 (IGBP3) on chromosome 7.

C. Larsson, H. Luthman, D. Powell, 1992, Genomics.

Insulin-like growth factor (IGF) binding protein complementary deoxyribonucleic acid from human HEP G2 hepatoma cells: predicted protein sequence suggests an IGF binding domain different from those of the IGF-I and IGF-II receptors.

D. Powell, J. Shively, R. Hintz, 1988, Molecular endocrinology.

Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo

D. Powell, 2006, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements.

D. Powell, A. Suwanichkul, S. L. Morris, 1994, The Journal of biological chemistry.

The promoter of the human gene for insulin-like growth factor binding protein-1. Basal promoter activity in HEP G2 cells depends upon liver factor B1.

D. Powell, A. Suwanichkul, M. Cubbage, 1990, The Journal of biological chemistry.

Insulin-like Growth Factor-binding Protein-3 Binds Fibrinogen and Fibrin*

D. Powell, P. Campbell, S. Durham, 1999, The Journal of Biological Chemistry.

Effect of progestin, antiprogestin, and relaxin on the accumulation of prolactin and insulin-like growth factor-binding protein-1 messenger ribonucleic acid in human endometrial stromal cells.

D. Powell, J. Gao, L. Tseng, 1992, Biology of reproduction.

High molecular weight forms of insulin-like growth factor II and its binding protein identified by protein immunoblotting.

D. Powell, F. Liu, R. Hintz, 1988, Biochemical and biophysical research communications.

Nephronophthisis and Retinal Degeneration in Tmem218–/– Mice

Z. Ding, D. Powell, G. Hansen, 2015, Veterinary pathology.

Human reprogramming roadmap unveils route to induced trophoblast stem cells 1 2

John F. Ouyang, Haroon Naeem, P. Das, 2020 .

Requirement for Class II Phosphoinositide 3-Kinase C2α in Maintenance of Glomerular Structure and Function

D. Powell, K. Moberg, N. Xu, 2010, Molecular and Cellular Biology.

Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5.

C. Larsson, H. Luthman, D. Powell, 1994, The Journal of biological chemistry.

LX4211 therapy reduces postprandial glucose levels in patients with type 2 diabetes mellitus and renal impairment despite low urinary glucose excretion.

Alan G. E. Wilson, P. Lapuerta, D. Powell, 2015, Clinical therapeutics.

GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4

Y. Hu, Z. Ding, W. K. Sonnenburg, 2009, Journal of Lipid Research.

Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)

Y. Hu, W. K. Sonnenburg, D. Powell, 2009, Journal of Biological Chemistry.

Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.

Alan G. E. Wilson, T. Stouch, S. D. Kimball, 2008, Journal of medicinal chemistry.

Potential positive and negative consequences of ZnT8 inhibition.

Eric P. Skaar, L. Davis, J. K. Oeser, 2020, The Journal of endocrinology.

The Sixth Symposium on Growth and Development in Children with Chronic Renal Failure¶11–13 March 1999, New York, USA

B. Tönshoff, D. Powell, F. Kaskel, 2000, Pediatric Nephrology.

Generation of a New Congenic Mouse Strain to Test the Relationships Among Serum Insulin‐like Growth Factor I, Bone Mineral Density, and Skeletal Morphology In Vivo

G. Churchill, M. Bouxsein, L. Donahue, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mapping quantitative trait loci for serum insulin-like growth factor-1 levels in mice.

G. Churchill, L. Donahue, D. Powell, 2000, Bone.

Insulin-like growth factor binding proteins as growth inhibitors in children with chronic renal failure

D. Powell, Phillip D. K. Lee, R. Hintz, 1996, Pediatric Nephrology.

IGF-2 and Unsaturated Somatomedin Carrier Proteins in Children With Chronic Renal Failure

D. Powell, R. Hintz, R. Rosenfeld, 1987 .

Identification of insulin-like growth factor binding proteins in breast cancer cells

D. Yee, D. Powell, M. Lippman, 1991, Breast Cancer Research and Treatment.

LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)–Mediated Absorption of Intestinal Glucose

F. Mseeh, Z. Ding, D. Powell, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Type 2 Diabetes–Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis

Matthew T. Dickerson, D. Powell, D. Jacobson, 2015, Diabetes.

The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct*

J. K. Oeser, R. O’Brien, D. Powell, 2003, The Journal of Biological Chemistry.

Hepatic nuclear factor 3 and high mobility group I/Y proteins bind the insulin response element of the insulin-like growth factor-binding protein-1 promoter.

D. Powell, S. Durham, A. Suwanichkul, 1997, Endocrinology.

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2012, Clinical pharmacology and therapeutics.

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, Journal of medicinal chemistry.

Effects of LX4211, a dual SGLT1/SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes.

Z. Ding, D. Powell, A. Sands, 2013, Clinical therapeutics.

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

E. Wright, V. Kepe, J. Barrio, 2017, Journal of the American Society of Nephrology : JASN.

Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid.

B. Riggs, C. Conover, D. Powell, 1996, Endocrinology.

The Physiological Effects of Deleting the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Are Influenced by Gender and Genetic Background

R. O’Brien, A. Ustione, D. Piston, 2012, PloS one.

Activation of the insulin-like growth factor binding protein-1 promoter by progesterone receptor in decidualized human endometrial stromal cells

D. Powell, A. Suwanichkul, L. Tseng, 1999, Molecular and Cellular Endocrinology.

Conservation of a growth hormone-responsive promoter element in the human and mouse acid-labile subunit genes.

D. Powell, S. Durham, A. Suwanichkul, 2000, Endocrinology.

Inducible knock out of pregnancy-associated plasma protein-a gene expression in the adult mouse: effect on vascular injury response.

C. Conover, D. Powell, L. Bale, 2013, Endocrinology.

Multihormonal regulation of IGFBP-1 promoter activity.

D. Powell, A. Suwanichkul, P. D. Lee, 1993, Advances in experimental medicine and biology.

Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models

Alan G. E. Wilson, F. Mseeh, Z. Ding, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Plasminogen binds the heparin-binding domain of insulin-like growth factor-binding protein-3

D. Powell, P. Campbell, S. Durham, 1998 .

Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells.

S. Mohan, D. Powell, D. Baylink, 1997, Endocrinology.

Proteinuria and Perinatal Lethality in Mice Lacking NEPH1, a Novel Protein with Homology to NEPHRIN

R. Ramirez-Solis, C. A. Montgomery, D. Powell, 2001, Molecular and Cellular Biology.

High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes

M. Estecio, D. Powell, A. Sands, 2014, Bone Research.

Genetic disruption of brain serotonin content in mice produces leanness with hyperphagia and elevated physical activity but minimal skeletal changes

D. Powell, R. Brommage, Jeff Liu, 2014 .

Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns

D. Powell, P. Vogel, R. Brommage, 2019, Disease Models & Mechanisms.

Insulin-like growth factor (IGF) binding protein-1 is an antigonadotropin: evidence that optimal follicle-stimulating hormone action in ovarian granulosa cells is contingent upon amplification by endogenously-derived IGFs.

E. Adashi, D. Powell, R. Koistinen, 1993, Advances in experimental medicine and biology.

Hepatic nuclear factor 3 and high mobility group I/Y proteins bind the insulin response element of the insulin-like growth factor-binding protein-1 promoter.

D. Powell, S. Durham, A. Suwanichkul, 1997, Endocrinology.

Improved glycemic control in mice lacking Sglt1 and Sglt2.

F. Mseeh, Z. Ding, D. Powell, 2013, American journal of physiology. Endocrinology and metabolism.

FoxO1 Regulates Multiple Metabolic Pathways in the Liver

K. Heidenreich, D. Stolz, M. Montminy, 2006, Journal of Biological Chemistry.

LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)–Mediated Absorption of Intestinal Glucose

F. Mseeh, Z. Ding, D. Powell, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

V. Kepe, J. Barrio, N. Satyamurthy, 2017, Journal of the American Society of Nephrology : JASN.

Decreased hepatic insulin-like growth factor (IGF)-I and increased IGF binding protein-1 and -2 gene expression in experimental uremia.

B. Tönshoff, D. Powell, R. Baxter, 1997, Endocrinology.

Role of three FKHR phosphorylation sites in insulin inhibition of FKHR action in hepatocytes.

D. Powell, S. Durham, A. Suwanichkul, 2001, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3',5'-cyclic adenosine monophosphate is additive in HepG2 cells.

L. Giudice, F. Kaper, A. Giaccia, 2000, The Journal of clinical endocrinology and metabolism.