R. Ricciardi

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Transformation and Tumorigenesis Mediated by the Adenovirus E1A and E1B Oncogenes

R. Ricciardi, 1995 .

Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding.

R. Ricciardi, S. Hou, Hancheng Guan, 2003, The Journal of biological chemistry.

Kaposi's sarcoma-associated herpesvirus processivity factor-8 dimerizes in cytoplasm before being translocated to nucleus.

R. Ricciardi, Xulin Chen, Xia Zhou, 2010, Biochemical and biophysical research communications.

Human Kaposi's Sarcoma Herpesvirus Processivity Factor-8 Functions as a Dimer in DNA Synthesis*

R. Ricciardi, Xulin Chen, Kai Lin, 2004, Journal of Biological Chemistry.

The 41-kDa protein of human herpesvirus 6 specifically binds to viral DNA polymerase and greatly increases DNA synthesis.

R. Ricciardi, K. Lin, 1998, Virology.

Arrangement of messenger RNAs and protein coding sequences in the major late transcription unit of adenovirus 2.

M. Mathews, R. Ricciardi, B. Paterson, 1980, Journal of molecular biology.

Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.

R. Ricciardi, J. Miller, B. Roberts, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Molecular cloning and characterization of an antigen associated with early stages of melanoma tumor progression.

M. Isobe, C. Croce, K. Huebner, 1988, Cancer research.

Evidence for the involvement of a nuclear NF-kappa B inhibitor in global down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells

R. Ricciardi, X. Liu, R. Ge, 1996, Molecular and cellular biology.

cells . enhancer in adenovirus type 12-transformed of the major histocompatibility complex class I NF-kappa B inhibitor in global down-regulation Evidence for the involvement of a nuclear

Xiaohong Liu, R. Ricciardi, 1995 .

Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding

R. Weinmann, R. Ricciardi, R. Ge, 1992, Journal of virology.

Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element

R. Weinmann, R. Ricciardi, U. Graeven, 1992, Journal of virology.

Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by adenovirus inhibits growth of established CRC cells in mice.

R. Ricciardi, É. Gönczöl, H. Maruyama, 1997, Journal of immunology.

Association of histone deacetylase with COUP-TF in tumorigenic Ad12-transformed cells and its potential role in shut-off of MHC class I transcription.

R. Ricciardi, S. Hou, D. Smirnov, 2000, Virology.

Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase.

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Processivity factor of KSHV contains a nuclear localization signal and binding domains for transporting viral DNA polymerase into the nucleus.

R. Ricciardi, Yali Chen, Mihai Ciustea, 2005, Virology.

Identification of the c-myc oncogene product in normal and malignant B cells.

C. Croce, E. Appella, R. Ricciardi, 1983, Science.

Tumorigenic Adenovirus Type 12 E1A Inhibits Phosphorylation of NF-κB by PKAc, Causing Loss of DNA Binding and Transactivation

R. Ricciardi, Hancheng Guan, Junfang Jiao, 2007, Journal of Virology.

Tumorigenic adenovirus 12 cells evade NK cell lysis by reducing the expression of NKG2D ligands.

J. Orange, R. Ricciardi, A. Makrigiannis, 2012, Immunology letters.

Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2015, BMC Structural Biology.

Detailed kinetics of adenovirus type-5 steady-state transcripts during early infection.

R. Ricciardi, G. M. Glenn, 1988, Virus research.

BK virus-plasmid expression vector that persists episomally in human cells and shuttles into Escherichia coli

M. Negrini, R. Ricciardi, A. Caputo, 1984, Molecular and cellular biology.

How reliable is amino acid sequence homology in predicting similarity of structure and function of c-myc and Ad12 E1A oncogenic proteins?

R. Ricciardi, B. Ghrist, 2005, Journal of Molecular Evolution.

Debulking different Corona (SARS-CoV-2 delta, omicron, OC43) and Influenza (H1N1, H3N2) virus strains by plant viral trap proteins in chewing gums to decrease infection and transmission

Che Ma, R. Ricciardi, K. Margulies, 2022, Biomaterials.

Human melanoma cells transcribe interleukin 1 genes identical to those of monocytes.

R. Ricciardi, H. Koprowski, D. Guerry, 1991, Cancer research.

Fusion of adenovirus E1A to the glucocorticoid receptor by high-resolution deletion cloning creates a hormonally inducible viral transactivator

R. Ricciardi, S. Hollenberg, D. Becker, 1989, Molecular and cellular biology.

The ElA Products of Oncogenic Adenovirus Serotype

P. Yaciuk, R. Ricciardi, Maurice Green, 2022 .

Specificity of the mouse cytotoxic T lymphocyte response to adenovirus 5. E1A is immunodominant in H-2b, but not in H-2d or H-2k mice.

R. Ricciardi, P. Duerksen-Hughes, W. Wold, 1991, Journal of immunology.

R-looping and structural gene indentification of recombinant DNA.

M. Rosbash, J. Woolford, R. Ricciardi, 1979, Methods in enzymology.

The N Terminus of Adenovirus Type 12 E1A Inhibits Major Histocompatibility Complex Class I Expression by Preventing Phosphorylation of NF-κB p65 Ser276 through Direct Binding

R. Ricciardi, Hancheng Guan, Andrew M. Lippa, 2010, Journal of Virology.

The viral oncoproteins Ad5 E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110.

J. Mazzarelli, J. V. Geisberg, R. Ricciardi, 1995, Oncogene.

trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor

R. Ricciardi, L. C. Webster, Leland C. Webster, 1991, Molecular and cellular biology.

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.

J. Culp, C. Smith, R. Ricciardi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The processivity factor complex of feline herpes virus-1 is a new drug target.

R. Ricciardi, Hancheng Guan, Y. L. Saw, 2015, Antiviral research.

Murine cell lines stably expressing the influenza virus hemagglutinin gene introduced by a recombinant retrovirus vector are constitutive targets for MHC class I- and class II-restricted T lymphocytes.

J. Yewdell, J. Bennink, L. Eisenlohr, 1989, Journal of immunology.

Adenovirus type 12 E1A gene represses accumulation of MHC class I mRNAs at the level of transcription.

R. Ricciardi, D. Friedman, David J. Friedman, 1988, Virology.

E1A-based determinants of oncogenicity in human adenovirus groups A and C.

R. Ricciardi, Y. Zhang, S. Hou, 2004, Current topics in microbiology and immunology.

Transformation of normal human melanocytes and non‐malignant nevus cells by adenovirus 12‐SV40 hybrid virus

M. Herlyn, R. Ricciardi, H. Koprowski, 1989, International journal of cancer.

A novel cis element essential for stimulated transcription of the p41 promoter of human herpesvirus 6

J. Thompson, R. Ricciardi, A. Agulnick, 1994, Journal of virology.

An element of the BK virus enhancer required for DNA replication

R. Ricciardi, A. D. Del Vecchio, R. Steinman, 1989, Journal of virology.

An adenovirus type 5 E1A protein with a single amino acid substitution blocks wild-type E1A transactivation

R. Ricciardi, G. M. Glenn, 1987, Molecular and cellular biology.

Transactivation of BKV and SV40 early promoters by BKV and SV40 T-antigens.

R. Ricciardi, A. Caputo, G. Barbanti‐Brodano, 1986, Virology.

ElA Protein with a Single Amino Acid Substitution Blocks Wild-Type ElA Transactivation

R. Ricciardi, Gary M. GLENNt, 2022 .

E1A is the component of the MHC class I enhancer complex that mediates HDAC chromatin repression in adenovirus-12 tumorigenic cells.

R. Ricciardi, Biwei Zhao, 2006, Virology.

Expression of hepatitis B surface antigen in human cells by a recombinant BK virus DNA vector.

R. Ricciardi, A. Caputo, G. Milanesi, 1988, The Journal of general virology.

In Adenovirus Type 12 Tumorigenic Cells, Major Histocompatibility Complex Class I Transcription Shutoff Is Overcome by Induction of NF-κB and Relief of COUP-TFII Repression

R. Ricciardi, S. Hou, Hancheng Guan, 2002, Journal of Virology.

The E1A products of oncogenic adenovirus serotype 12 include amino-terminally modified forms able to bind the retinoblastoma protein but not p300

P. Yaciuk, E. Moran, H. G. Wang, 1993, Journal of virology.

Methods utilizing cell-free protein-synthesizing systems for the identification of recombinant DNA molecules.

R. Ricciardi, B. Paterson, J. Miller, 1983, Methods in enzymology.

Adenovirus type 12 early region 1A proteins repress class I HLA expression in transformed human cells.

R. Ricciardi, R. Vasavada, A. Caputo, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C‐Terminal tripeptide of the vaccinia D4 processivity factor

R. Ricciardi, Hancheng Guan, R. Scott, 2019, Antiviral Research.

Age dependent changes in fungi: Ribosomes and protein synthesis inRhizoctonia solani mycelium

R. Ricciardi, D. Hollomon, D. Gottlieb, 1974, Archives of Microbiology.

Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.

J. Culp, B. Chance, R. Ricciardi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2011, Journal of medicinal chemistry.

Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis.

R. Shoemaker, R. Ricciardi, S. Sei, 2006, Antiviral research.

Design of potent poxvirus inhibitors of the heterodimeric processivity factor required for viral replication.

R. Ricciardi, Hancheng Guan, Y. L. Saw, 2013, Journal of medicinal chemistry.

Associated with Early Stages of Melanoma Tumor Progression Molecular Cloning and Characterization of an Antigen Updated

M. Isobe, C. Croce, K. Huebner, 2006 .

Molecular Cloning and Characterization of an Antigen Associated with Early Stages of Melanoma Tumor Progression 1

M. Isobe, C. Croce, K. Huebner, 2006 .

Translation of PVX RNA in vitro by wheat germ. I. Characterization of the reaction and product size.

R. M. Goodman, R. Ricciardi, D. Gottlieb, 1978, Virology.

Analysis of terminal structures of RNA from potato virus X.

N. Sonenberg, A. Shatkin, R. M. Goodman, 1978, Nucleic acids research.

Identification of a DNA-binding protein of human herpesvirus 6, a putative DNA polymerase stimulatory factor.

J. Thompson, R. Ricciardi, A. Agulnick, 1993, The Journal of general virology.

Phosphorylation within the transactivation domain of adenovirus E1A protein by mitogen-activated protein kinase regulates expression of early region 4

N. Ahn, P. Branton, A. Whalen, 1997, Journal of virology.

Production of a monospecific antiserum against the early region 1A proteins of adenovirus 12 and adenovirus 5 by an adenovirus 12 early region 1A-beta-galactosidase fusion protein antigen expressed in bacteria

M. O. Scott, D. Norris, R. Ricciardi, 1984, Journal of virology.

Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach.

R. Shoemaker, R. Ricciardi, Janice Elaine Y Silverman, 2008, Antiviral research.

An adenovirus mRNA which encodes a 14,700-Mr protein that maps to the last open reading frame of region E3 is expressed during infection

M. O. Scott, R. Ricciardi, E. Wang, 1988, Journal of virology.

Expression and purification of recombinant Kaposi's sarcoma-associated herpesvirus DNA polymerase using a Baculovirus vector system.

R. Shoemaker, R. Ricciardi, R. Fisher, 2003, Protein expression and purification.

A rapid plate assay for the screening of inhibitors against herpesvirus DNA polymerases and processivity factors.

R. Ricciardi, K. Lin, 2000, Journal of virological methods.

Cloning and Functional Analysis of Kaposi’s Sarcoma-Associated Herpesvirus DNA Polymerase and Its Processivity Factor

R. Ricciardi, C. Y. Dai, Kai Lin, 1998, Journal of Virology.

DNA Binding of Repressor Nuclear Factor-κB p50/p50 Depends on Phosphorylation of Ser337 by the Protein Kinase A Catalytic Subunit*

R. Ricciardi, S. Hou, Hancheng Guan, 2005, Journal of Biological Chemistry.

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

E. Lees, A. Berk, R. Ricciardi, 1999, Nature.

Transformation by E1A Oncoprotein Involves Ubiquitin-Mediated Proteolysis of the Neuronal and Tumor Repressor REST in the Nucleus

R. Ricciardi, Hancheng Guan, H. Guan, 2012, Journal of Virology.

Tumorigenesis by Adenovirus Type 12 E1A

R. Ricciardi, Hancheng Guan, H. Guan, 2012 .

Induction of Neuronal and Tumor-Related Genes by Adenovirus Type 12 E1A

R. Ricciardi, Hancheng Guan, Jim F. Williams, 2008, Journal of Virology.

Phosphorylation of Serine 337 of NF-κB p50 Is Critical for DNA Binding*

R. Ricciardi, S. Hou, Hancheng Guan, 2003, Journal of Biological Chemistry.

The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135

J. Mazzarelli, R. Ricciardi, I. Davidson, 1997, Journal of virology.

Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions

R. Ricciardi, G. M. Glenn, 1985, Journal of virology.

The size and topology of single-stranded DNA from bean golden mosaic virus.

R. M. Goodman, R. Ricciardi, D. Reisman, 1979, Virology.

Cellular protein differences between nontumorigenic Ad5 and tumorigenic Ad12 transformed mouse cells.

R. Ricciardi, J. Sawicki, K. Eager, 1986, Virology.

Expression of histocompatibility antigens H-2K, -D, and -L is reduced in adenovirus-12-transformed mouse cells and is restored by interferon gamma.

E. Appella, D. Breiding, R. Ricciardi, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Identification of genes associated with adenovirus 12 tumorigenesis by microarray.

R. Ricciardi, Hancheng Guan, D. Smirnov, 2003, Virology.

Tumorigenic Adenovirus Type 12 E1A Inhibits Phosphorylation of NF- (cid:2) B by PKAc, Causing Loss of DNA Binding and Transactivation (cid:1)

R. Ricciardi, Hancheng Guan, Junfang Jiao, 2007 .

Transactivation PKAc , Causing Loss of DNA Binding and B by κ Inhibits Phosphorylation of NF-Tumorigenic Adenovirus Type 12 E 1 A

R. Ricciardi, Hancheng Guan, Junfang Jiao, 2007 .

Reduced Phosphorylation of p50 Is Responsible for Diminished NF-κB Binding to the Major Histocompatibility Complex Class I Enhancer in Adenovirus Type 12-Transformed Cells

D. Kushner, R. Ricciardi, 1999, Molecular and Cellular Biology.

Subregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complex

J. V. Geisberg, J. Chen, R. Ricciardi, 1995, Molecular and cellular biology.

Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.

R. Ricciardi, Mihai Ciustea, Janice Elaine Y. Silverman, 2008, Journal of medicinal chemistry.

Identification of Protein-Protein Interaction Inhibitors Targeting Vaccinia Virus Processivity Factor for Development of Antiviral Agents

James W. Noah, Mark N. Prichard, N. Schormann, 2011, Antimicrobial Agents and Chemotherapy.

Identiﬁcation of Protein-Protein Interaction Inhibitors Targeting Vaccinia Virus Processivity Factor for Development of Antiviral Agents (cid:1) †

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2011 .

A Conserved Tripeptide Sequence at the C Terminus of the Poxvirus DNA Processivity Factor D4 Is Essential for Protein Integrity and Function*

R. Ricciardi, Hancheng Guan, M. Nuth, 2016, The Journal of Biological Chemistry.

Uracil‐DNA glycosylases—Structural and functional perspectives on an essential family of DNA repair enzymes

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2014, Protein science : a publication of the Protein Society.

Discovery of a potent cytotoxic agent that promotes G2/M phase cell cycle arrest and apoptosis in a malignant human pharyngeal squamous carcinoma cell line.

R. Ricciardi, M. Benakanakere, M. Nuth, 2022, International journal of oncology.

Poxvirus uracil‐DNA glycosylase—An unusual member of the family I uracil‐DNA glycosylases

P. Prevelige, N. Schormann, R. Gillilan, 2016, Protein science : a publication of the Protein Society.

Vaccinia Virus D4 Mutants Defective in Processive DNA Synthesis Retain Binding to A20 and DNA

R. Ricciardi, D. Chattopadhyay, Janice Elaine Y. Silverman, 2010, Journal of Virology.

Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection

D. Weiner, R. N. Harty, R. Ricciardi, 2021, Molecular Therapy.

An ATF/CREB site is the major regulatory element in the human herpesvirus 6 DNA polymerase promoter

J. Thompson, R. Ricciardi, A. Agulnick, 1994, Journal of virology.

An adenovirus recombinant that expresses the human cytomegalovirus major envelope glycoprotein and induces neutralizing antibodies.

R. Ricciardi, É. Gönczöl, S. Plotkin, 1990, The Journal of infectious diseases.

Herpes simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis.

R. Ricciardi, Hancheng Guan, C. Mitchell, 2020, The ocular surface.

A Novel Target and Approach for Identifying Antivirals against Molluscum Contagiosum Virus

R. Ricciardi, Hancheng Guan, S. Isaacs, 2014, Antimicrobial Agents and Chemotherapy.

Negative regulation by the R2 element of the MHC class I enhancer in adenovirus-12 transformed cells correlates with high levels of COUP-TF binding.

A. Cooney, M. Tsai, S. Westmoreland, 1994, Oncogene.

The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein.

J. V. Geisberg, R. Ricciardi, A. J. Berk, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi's Sarcoma-Associated Herpesvirus

D. Filman, R. Ricciardi, D. Coen, 2009, Journal of Virology.

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

P. Sharp, C. Cepko, R. Ricciardi, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase

N. Schormann, R. Ricciardi, D. Chattopadhyay, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Coup-TFII is up-regulated in adenovirus type 12 tumorigenic cells and is a repressor of MHC class I transcription.

Xiaohong Liu, R. Ricciardi, S. Hou, 2001, Virology.

Chromatin repression by COUP-TFII and HDAC dominates activation by NF-kappaB in regulating major histocompatibility complex class I transcription in adenovirus tumorigenic cells.

R. Ricciardi, S. Hou, Biwei Zhao, 2003, Virology.

The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kappa B to the MHC class I enhancer in transformed cells.

D. Kushner, R. Ricciardi, F. Graham, 1996, Oncogene.

E1A oncogene of adenovirus-12 mediates trans-repression of MHC class I transcription in Ad5/Ad12 somatic hybrid transformed cells.

R. Ricciardi, X. Liu, R. Ge, 1994, Virology.

Modulation of major histocompatibility complex (MHC) class I genes in adenovirus 12 transformed cells: interferon-gamma increases class I expression by a mechanism that circumvents E1A induced-repression and tumor necrosis factor enhances the effect of interferon-gamma.

R. Ricciardi, K. Pfizenmaier, K. Eager, 1989, Oncogene.

CTL recognition of adenovirus-transformed cells infected with influenza virus: lysis by anti-influenza CTL parallels adenovirus-12-induced suppression of class I MHC molecules.

J. Yewdell, J. Bennink, R. Ricciardi, 1988, Virology.

Oligomerization properties of the viral oncoproteins adenovirus E1A and human papillomavirus E7 and their complexes with the retinoblastoma protein.

J. Mazzarelli, R. Marmorstein, R. Ricciardi, 2000, Biochemistry.

Rapid screening of chemical inhibitors that block processive DNA synthesis of herpesviruses: potential application to high-throughput screening.

R. Shoemaker, R. Ricciardi, S. Sei, 2005, Methods in molecular biology.

A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential.

R. Ricciardi, A. Reitz, R. Scott, 2023, Antiviral research.

Design of potent poxvirus inhibitors of the heterodimeric processivity factor required for viral replication.

R. Ricciardi, Y. L. Saw, M. Nuth, 2013, Journal of medicinal chemistry.

Down-regulation of MHC class I antigen in insulinoma cells controlled by the R1 element of the H-2 enhancer.

R. Ricciardi, B. Knowles, R. Ge, 1994, Oncogene.

The RITE assay: identifying effectors that target the transcription machinery using phage display technology.

J. Mazzarelli, R. Ricciardi, 2001, BioTechniques.