Zhiheng Xu

发表

Discovery of potent and selective CDK8 inhibitors through FBDD approach.

Xingchun Han, Min Jiang, Chengang Zhou, 2017, Bioorganic & medicinal chemistry letters.

Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.

B. Kuhn, W. Haap, M. Stahl, 2016, ACS medicinal chemistry letters.

Direct Inhibition of Hepatitis B e Antigen by Core Protein Allosteric Modulator

J. Young, Zheng Zhou, Zhiheng Xu, 2019, Hepatology.

Identification of New ATG4B Inhibitors Based on a Novel High-Throughput Screening Platform

B. Kuhn, M. Stahl, C. Liu, 2017, SLAS discovery : advancing life sciences R & D.

Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

F. García-Alcalde, J. Young, Zhiheng Xu, 2017, Scientific Reports.

Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors.

J. Wu, J. Young, Zheng Zhou, 2017, Journal of medicinal chemistry.

Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors.

J. Wu, Min Jiang, Zheng Zhou, 2016, Journal of medicinal chemistry.

Targeting Hippo pathway by specific interruption of YAP‐TEAD interaction using cyclic YAP‐like peptides

J. Luk, Zheng Zhou, Zhiheng Xu, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.

J. Wong, Zheng Zhou, Zhiheng Xu, 2014, ACS medicinal chemistry letters.

Discovery of Pyrido[2,3-b]indole Derivatives with Gram-negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.

Chengang Zhou, Zheng Zhou, Zhiheng Xu, 2020, Journal of medicinal chemistry.

A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection

Zhiheng Xu, U. Protzer, F. Vondran, 2019, Antimicrobial Agents and Chemotherapy.

Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.

B. Kuhn, W. Haap, M. Stahl, 2016, ACS medicinal chemistry letters.