A. Mayweg

发表

Discovery of potent and selective CDK8 inhibitors through FBDD approach.

Xingchun Han, Min Jiang, Chengang Zhou, 2017, Bioorganic & medicinal chemistry letters.

Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.

Wolfgang Guba, Gisbert Schneider, Jochem Alsenz, 2008, Journal of medicinal chemistry.

β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.

Wolfgang Guba, Harald Mauser, Mark Rogers-Evans, 2013, Journal of medicinal chemistry.

EGFR Oncogenes Expressed In Glioblastoma Are Activated As Covalent Dimers And Paradoxically Stimulated By Erlotinib

A. Flohr, A. Mayweg, N. Ishiyama, 2019, bioRxiv.

Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2).

Rainer E. Martin, B. Kuhn, A. Mayweg, 2016, Organic & biomolecular chemistry.

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.

Rainer E. Martin, B. Kuhn, A. Kuglstatter, 2015, Journal of medicinal chemistry.

Transannular, decarboxylative Claisen rearrangement reactions for the synthesis of sulfur-substituted vinylcyclopropanes.

M. Lansdell, A. Mayweg, A. White, 2010, Chemical communications.

Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action.

Xingchun Han, Min Jiang, Chengang Zhou, 2018, Journal of medicinal chemistry.

A concise, selective synthesis of the polyketide spacer domain of a potent bryostatin analogue.

A. Mayweg, P. Wender, C. Vandeusen, 2003, Organic letters.

Expedient synthesis of a highly substituted tropolone via a 3-oxidopyrylium [5+2] cycloaddition reaction

A. Mayweg, J. Baldwin, R. Adlington, 2003 .

Chapter Seventeen – Novel Therapeutics in Discovery and Development for Treatment of Chronic HBV Infection

J. Wu, A. Mayweg, Guozhi Tang, 2013 .

Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.

B. Kuhn, A. Kuglstatter, S. Müller, 2020, Journal of medicinal chemistry.

Transannular Claisen rearrangement reactions for the synthesis of vinylcyclobutanes: formal synthesis of (±)-grandisol.

A. Mayweg, D. Craig, Sophie J Gore, 2011, Organic & biomolecular chemistry.

Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide.

A. Mayweg, J. Baldwin, R. Adlington, 2002, Organic letters.

Studies toward the biomimetic synthesis of tropolone natural products via a hetero Diels-Alder reaction.

A. Mayweg, J. Baldwin, K. Neumann, 1999, Organic letters.

Late-stage intermolecular CH activation for lead diversification: a highly chemoselective oxyfunctionalization of the C-9 position of potent bryostatin analogues.

Paul A Wender, A. Mayweg, P. Wender, 2005, Organic letters.

ROCK: the Roche medicinal chemistry knowledge application - design, use and impact.

Patrick Schnider, Alexander Mayweg, Urs Hofer, 2011, Drug discovery today.

Studies towards the Synthesis of Lindenene: Unexpected Stereochemical Outcome of an Intramolecular Cyclopropanation Reaction and Synthesis of (±)-epi-Lindenene and (±)-iso-Lindenene

A. Mayweg, J. Baldwin, R. Adlington, 2007 .

Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors.

J. Wu, J. Young, Zheng Zhou, 2017, Journal of medicinal chemistry.

Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors.

J. Wu, Min Jiang, Zheng Zhou, 2016, Journal of medicinal chemistry.

Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.

J. Wong, Zheng Zhou, Zhiheng Xu, 2014, ACS medicinal chemistry letters.

BACE1 inhibitors: a head group scan on a series of amides.

W. Guba, D. Banner, E. Pinard, 2013, Bioorganic & medicinal chemistry letters.

Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114

A. Mayweg, F. Roussi, J. Baldwin, 2001 .

Studies Towards the Synthesis of Lindenene: Unexpected Stereochemical Outcome of an Intramolecular Cyclopropanation Reaction and Synthesis of (.+-.)-epi-Lindenene and (.+-.)-iso-Lindenene.

A. Mayweg, J. Baldwin, R. Adlington, 2008 .