G. Ghirlanda

发表

Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations

S. Ozkan, I. C. Kazan, Prerna Sharma, 2020, bioRxiv.

A Rigid Hinge Region Is Necessary for High-Affinity Binding of Dimannose to Cyanovirin and Associated Constructs.

C. Margulis, S. Ozkan, A. Bobkov, 2015, Biochemistry.

Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution

Petra Fromme, Giovanna Ghirlanda, P. Fromme, 2008, Protein science : a publication of the Protein Society.

A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity.

Petra Fromme, Barbara Giomarelli, Giovanna Ghirlanda, 2007, Biochemistry.

Protein secondary-shell interactions enhance the photoinduced hydrogen production of cobalt protoporphyrin IX.

G. Ghirlanda, Michael Vaughn, D. Sommer, 2014, Chemical communications.

Water oxidation by a nickel-glycine catalyst.

G. Ghirlanda, Dong Wang, James P. Allen, 2014, Journal of the American Chemical Society.

A flexible docking scheme efficiently captures the energetics of glycan-cyanovirin binding.

S. Ozkan, G. Ghirlanda, Ashini Bolia, 2014, Biophysical journal.

The antiviral lectin cyanovirin-N: probing multivalency and glycan recognition through experimental and computational approaches.

S. Ozkan, G. Ghirlanda, Ashini Bolia, 2013, Biochemical Society transactions.

Simultaneous Observation of Peptide Backbone Lipid Solvation and α‐Helical Structure by Deep‐UV Resonance Raman Spectroscopy

R. Jiji, G. Ghirlanda, J. Beatty, 2011, Chembiochem : a European journal of chemical biology.

Design of a functional membrane protein by engineering a heme-binding site in glycophorin A.

J. Lear, G. Ghirlanda, Jeanine M. Cordova, 2007, Journal of the American Chemical Society.

De novo design of a D2-symmetrical protein that reproduces the diheme four-helix bundle in cytochrome bc1.

A. Wand, W. DeGrado, Kevin M Smith, 2004, Journal of the American Chemical Society.

Modulation of protein stability by O-glycosylation in a designed Gc-MAF analog.

Justin Spiriti, Giovanna Ghirlanda, A. van der Vaart, 2008, Biophysical chemistry.

A designed glycoprotein analogue of Gc-MAF exhibits native-like phagocytic activity.

G. Ghirlanda, Yung Chang, L. Joshi, 2006, Journal of the American Chemical Society.

D(n)-symmetrical tertiary templates for the design of tubular proteins.

Christopher M. Summa, C. M. Summa, W. DeGrado, 2001, Journal of molecular biology.

Psychophysical conditions and hormonal secretion in nurses on a rapidly rotating shift schedule and exposed to bright light during night work

G. Costa, G. Ghirlanda, J. Waterhouse, 1995 .

De novo design of functional proteins: Toward artificial hydrogenases.

G. Ghirlanda, D. Sommer, Anindya Roy, 2013, Biopolymers.

SARS-CoV-2 Infection in Health Workers: Analysis from Verona SIEROEPID Study during the Pre-Vaccination Era

G. Lippi, S. Porru, G. Ghirlanda, 2021, International journal of environmental research and public health.

Enhanced Photocatalytic Hydrogen Production by Hybrid Streptavidin-Diiron Catalysts.

G. Kodis, G. Ghirlanda, James P. Allen, 2020, Chemistry.

Rational design of a hexameric protein assembly stabilized by metal chelation

G. Ghirlanda, Chad K. Park, Mathieu E. Walther, 2018, Biopolymers.

A multivalent HIV-1 fusion inhibitor based on small helical foldamers

G. Ghirlanda, P. Scrimin, L. J. Prins, 2012, Tetrahedron.

A novel class of Calmodulin mimetics: De Novo designed proteins in molecular recognition

W. DeGrado, G. Ghirlanda, A. Lombardi, 2002 .

Design of Redox-Active Peptides: Towards Functional Materials.

G. Ghirlanda, D. Sommer, R. Alcala-Torano, 2016, Advances in experimental medicine and biology.

Modulation of cluster incorporation specificity in a de novo iron‐sulfur cluster binding peptide

G. Ghirlanda, A. Astashkin, D. Sommer, 2015, Biopolymers.

PNA-peptide assembly in a 3D DNA nanocage at room temperature.

Hao Yan, Petra Fromme, Su Lin, 2013, Journal of the American Chemical Society.

Repeat proteins as versatile scaffolds for arrays of redox-active FeS clusters† †Electronic supplementary information (ESI) available: All synthetic and material characterization procedures, characterization data and models of the CTPR-[4Fe–4S] assemblies. See DOI: 10.1039/c8cc06827e

G. Kodis, G. Ghirlanda, A. Cortajarena, 2019, Chemical communications.

Stabilization of coiled-coil peptide domains by introduction of trifluoroleucine.

N Vaidehi, W. DeGrado, N. Vaidehi, 2001, Biochemistry.

Amphiphilic copper(II) complexes modeled after the metal-complexation subunit of bleomycin antibiotics

G. Ghirlanda, P. Scrimin, A. Toffoletti, 1998 .

Self-assembled monolayers of Cu(II) metallosurfactants on GC and HOPG

A. Kaifer, G. Ghirlanda, L. Echegoyen, 1996 .

Catalysis by Peptide-Based Enzyme Models

G. Ghirlanda, P. Scrimin, L. J. Prins, 2010 .

Design of membrane proteins: toward functional systems.

Giovanna Ghirlanda, G. Ghirlanda, 2009, Current opinion in chemical biology.

Design of three-dimensional domain-swapped dimers and fibrous oligomers.

D. Eisenberg, W. DeGrado, J. Bryson, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Influence of Aggregation on Redox Potentials of Amphiphilic Cu(II) Complexes Modeled after Bleomycin Antibiotics

G. Ghirlanda, L. Echegoyen, P. Scrimin, 1996 .

A hydrolytic reporter of Cu(II) availability in artificial liposomes

G. Ghirlanda, P. Scrimin, P. Tecilla, 1993 .

A Designed “Nested” Dimer of Cyanovirin-N Increases Antiviral Activity

A. Bobkov, G. Ghirlanda, B. O’Keefe, 2016, Viruses.

Multivalent interactions with gp120 are required for the anti‐HIV activity of Cyanovirin

J. Mcmahon, G. Ghirlanda, Barbara Giomarelli, 2009, Biopolymers.

Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage

P. Fromme, G. Ghirlanda, Su Lin, 2014, Artificial DNA, PNA & XNA.

From synthetic coiled coils to functional proteins: automated design of a receptor for the calmodulin-binding domain of calcineurin.

W. DeGrado, J. Lear, G. Ghirlanda, 1998, Journal of molecular biology.

Design of dinuclear manganese cofactors for bacterial reaction centers.

G. Ghirlanda, Eduardo Espiritu, S. Edwardraja, 2016, Biochimica et biophysica acta.

Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability.

Yi Tang, David A Tirrell, Giovanna Ghirlanda, 2001, Angewandte Chemie.

Effect of bright light on tolerance to night work.

G. Costa, G. Ghirlanda, J. Waterhouse, 1993, Scandinavian journal of work, environment & health.

Modulation of function in a minimalist heme-binding membrane protein

G. Ghirlanda, S. Shinde, B. Woodrum, 2012, JBIC Journal of Biological Inorganic Chemistry.

A de novo designed 2[4Fe-4S] ferredoxin mimic mediates electron transfer.

D. Gust, G. Ghirlanda, A. Astashkin, 2014, Journal of the American Chemical Society.

De Novo Design of Iron-Sulfur Proteins.

G. Ghirlanda, Z. B. Dizicheh, N. Halloran, 2017, Methods in enzymology.

De novo design of an artificial bis[4Fe-4S] binding protein.

G. Ghirlanda, I. Sarrou, A. Astashkin, 2013, Biochemistry.

Biochemical and spectroscopic characterization of dinuclear Mn-sites in artificial four-helix bundle proteins.

G. Ghirlanda, Eduardo Espiritu, S. Edwardraja, 2017, Biochimica et biophysica acta. Bioenergetics.

Improved Electro- and Photocatalytic Water Reduction by Confined Cobalt Catalysts in Streptavidin

G. Ghirlanda, Sílvia Osuna, A. Romero‐Rivera, 2019, ACS Catalysis.

Reengineering cyt b562 for hydrogen production: A facile route to artificial hydrogenases.

G. Ghirlanda, J. Tomlin, D. Sommer, 2016, Biochimica et biophysica acta.

Light-Driven CO2 Reduction by Co-Cytochrome b 562

G. Ghirlanda, D. Sommer, R. Alcala-Torano, 2021, Frontiers in Molecular Biosciences.

Photo-induced hydrogen production in a helical peptide incorporating a [FeFe] hydrogenase active site mimic.

G. Ghirlanda, Christopher Madden, Anindya Roy, 2012, Chemical communications.

Slow Internal Dynamics and Charge Expansion in the Disordered Protein CGRP: A Comparison with Amylin.

G. Ghirlanda, Stephanie M. Cope, S. Vaiana, 2015, Biophysical journal.

Low temperature assembly of functional 3D DNA-PNA-protein complexes.

Hao Yan, P. Fromme, Yan Liu, 2014, Journal of the American Chemical Society.

Photoelectrochemical Water Oxidation by Cobalt Cytochrome C Integrated-ATO Photoanode

G. Ghirlanda, D. Seo, Shaojiang Chen, 2021, Catalysts.

Rational development of a high-affinity secretin receptor antagonist.

P. Sexton, A. Christopoulos, C. Reynolds, 2020, Biochemical pharmacology.

Design Strategies for Redox Active Metalloenzymes: Applications in Hydrogen Production.

G. Ghirlanda, D. Sommer, R. Alcala-Torano, 2016, Methods in enzymology.

Cyclic N-terminal loop of amylin forms non amyloid fibers.

R. Best, G. Ghirlanda, S. Shinde, 2013, Biophysical journal.

Editorial overview: The many facets of protein design: from self-assembled materials to vaccines.

Ivan V Korendovych, Giovanna Ghirlanda, I. Korendovych, 2018, Current opinion in structural biology.

Control of Permeation of Ions Across Vesicles and Chemical Differentiation of Their Bilayer Membrane

G. Ghirlanda, P. Scrimin, P. Tecilla, 1998 .

Lanthanide cleavage of phosphodiester liposomes

R. Moss, G. Ghirlanda, Byeong-deog Park, 1995 .

A hierarchic approach to the design of hexameric helical barrels.

D. Eisenberg, W. DeGrado, J. Lear, 2002, Journal of molecular biology.

Evaluation of a rapidly rotating shift system for tolerance of nurses to nightwork

G. Costa, G. Ghirlanda, J. Waterhouse, 1994, International archives of occupational and environmental health.

Engineering gain‐of‐function mutants of a WW domain by dynamics and structural analysis

S. Ozkan, I. C. Kazan, A. Bobkov, 2023, Protein science : a publication of the Protein Society.

A designed buried salt bridge modulates heterodimerization of a membrane peptide

G. Ghirlanda, M. Levitus, Bhupesh Goyal, 2014, Biopolymers.

Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability.

W. DeGrado, G. Ghirlanda, D. Tirrell, 2001, Angewandte Chemie.

Volatile anesthetic modulation of oligomerization equilibria in a hexameric model peptide

R. Eckenhoff, W. DeGrado, J. Johansson, 2004, FEBS letters.

Characterization of Small Metal-binding Protein ( SmbP ) From Nitrosomonas Europaea

G. Ghirlanda, James P. Allen, S. Bowen, 2010 .

Copper Environment in Artificial Metalloproteins Probed by Electron Paramagnetic Resonance Spectroscopy.

G. Ghirlanda, Dong Wang, S. Edwardraja, 2015, The journal of physical chemistry. B.