G. Baldwin

发表

Tyrosine modification enhances metal-ion binding.

R. Norton, G. Baldwin, M. Bailey, 2008, The Biochemical journal.

The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway

G. Baldwin, O. Patel, K. M. Marshall, 2009, Regulatory Peptides.

Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.

G. Baldwin, O. Patel, A. Shulkes, 2004, Biochemical pharmacology.

Expression of gastrin/CCK-B receptors does not lead to a mitogenic response to gastrin in two colon cell lines.

G. Baldwin, T. Mantamadiotis, A. Imdahl, 1999, The Journal of surgical research.

Gastrin-releasing peptide and cancer.

G. Baldwin, O. Patel, A. Shulkes, 2006, Biochimica et biophysica acta.

Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer

G. Baldwin, A. Shulkes, Nhi Huynh, 2016, Cancer biology & therapy.

Inhibition of p21 activated kinase enhances tumour immune response and sensitizes pancreatic cancer to gemcitabine.

G. Baldwin, Nhi Huynh, Hong He, 2017, International journal of oncology.

Activation of Src family tyrosine kinases by ferric ions.

R. Norton, G. Baldwin, B. Shehan, 2014, Biochimica et biophysica acta.

Gastrin, gastrin receptors and colorectal carcinoma

G. Baldwin, A. Shulkes, 1998, Gut.

Inhibition of the preferential binding of actin to the N-terminal hydratase domain of the 78-kDa gastrin-binding protein by non-steroidal anti-inflammatory drugs and gastrin receptor antagonists.

G. Baldwin, 2001, Biochemical pharmacology.

Histidine residues of zinc ligands in beta-lactamase II.

G. Baldwin, S. G. Waley, H. Hill, 1978, The Biochemical journal.

Identification of histidine residues that act as zinc ligands in beta-lactamase II by differential tritium exchange.

G. Baldwin, S. G. Waley, E. Abraham, 1979, The Biochemical journal.

The 1H nuclear-magnetic-resonance spectroscopy of cobalt(II)-beta-lactamase II.

G. Baldwin, S. G. Waley, H. Hill, 1980, The Biochemical journal.

Ferric ions inhibit proteolytic processing of progastrin.

G. Baldwin, O. Patel, G. Bramante, 2011, Biochemical and biophysical research communications.

Controlled overexpression of selected domains of the P85 subunit of phosphatidylinositol 3-kinase reverts v-Ha-Ras transformation.

G. Baldwin, Q. X. Zhang, I. D. Davis, 1996, Biochimica et biophysica acta.

Gastrin‐releasing peptide: Different forms, different functions

G. Baldwin, O. Patel, A. Shulkes, 2009, BioFactors.

Regulatory peptides: what do they regulate?

G. Baldwin, A. Shulkes, Andy Giraud, 2001, Trends in Endocrinology & Metabolism.

Circulating gastrin concentrations in patients at increased risk of developing colorectal carcinoma

G. Baldwin, A. Shulkes, F. Macrae, 2014, Journal of gastroenterology and hepatology.

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.

G. Baldwin, Nhi Huynh, Hong He, 2010, Biochimica et biophysica acta.

Inhibition of PAK1 suppresses pancreatic cancer by stimulation of anti-tumour immunity through down-regulation of PD-L1.

P. Timpson, G. Baldwin, C. Dumesny, 2019, Cancer letters.

Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent

Lin Xiao, K. Sethi, G. Baldwin, 2017, PloS one.

Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.

G. Baldwin, O. Patel, K. M. Marshall, 2015, Metallomics : integrated biometal science.

Normoxic regulation of HIF-1α in prostate cancer

G. Baldwin, O. Patel, A. Shulkes, 2014, Nature Reviews Urology.

Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF).

G. Baldwin, O. Patel, A. Shulkes, 2012, Endocrinology.

Zinc ion dyshomeostasis increases resistance of prostate cancer cells to oxidative stress via upregulation of HIF1α

G. Baldwin, O. Patel, A. Shulkes, 2018, Oncotarget.

Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo.

G. Baldwin, O. Patel, D. Westwood, 2014, Biochimica et biophysica acta.

Nucleotide sequence of porcine liver albumin.

G. Baldwin, J. Weinstock, 1988, Nucleic acids research.

Blockade of long chain fatty acid oxidation by non-steroidal anti-inflammatory drugs may contribute to inhibition of proliferation of human colorectal carcinoma cell lines.

G. Baldwin, F. Hollande, Z. Yang, 1998, Cancer letters.

Cyclooxygenase-2-selective antagonists do not inhibit growth of colorectal carcinoma cell lines.

V. Murphy, G. Baldwin, Z. Yang, 1998, Cancer letters.

Binding of nonsteroidal antiinflammatory drugs to the alpha-subunit of the trifunctional protein of long chain fatty acid oxidation.

V. Murphy, G. Baldwin, T. Hashimoto, 1998, The Journal of pharmacology and experimental therapeutics.

HGF regulates tight junctions in new nontumorigenic gastric epithelial cell line.

G. Baldwin, F. Hollande, R. Whitehead, 2001, American journal of physiology. Gastrointestinal and liver physiology.

The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo

G. Baldwin, O. Patel, K. M. Marshall, 2013, Peptides.

Isolation and partial characterization of methylated arginines from the encephalitogenic basic protein of myelin.

G. Baldwin, P. Carnegie, 1971, The Biochemical journal.

Nucleotide sequence encoding a novel member of the hydratase/dehydrogenase family.

G. Baldwin, T. Mantamadiotis, J. Weinstock, 1993, Biochimica et biophysica acta.

Inhibition of group 1 p21‐activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer

G. Baldwin, P. Phillips, Hong He, 2017, International journal of cancer.

FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine

G. Baldwin, A. Lowy, O. Patel, 2016, BMC Cancer.

Peptide processing and biology in human disease

G. Baldwin, A. Shulkes, S. Kovac, 2009, Current opinion in endocrinology, diabetes, and obesity.

PPARα agonists stimulate progastrin production in human colorectal carcinoma cells

G. Baldwin, A. Shulkes, S. Lachal, 2004, Regulatory Peptides.

Inhibition of cell proliferation by the cholecystokinin antagonist L-364,718.

G. Baldwin, C. Thumwood, J. Hong, 1991, Experimental cell research.

Interrelationships between circulating gastrin and iron status in mice and humans.

Kelly A. Smith, G. Baldwin, A. Shulkes, 2008, American journal of physiology. Gastrointestinal and liver physiology.

8 Gut hormones, growth and malignancy

G. Baldwin, R. Whitehead, 1994 .

Epidermal growth factor precursor is related to the translation product of the Moloney sarcoma virus oncogene mos.

G. Baldwin, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Developmental expression and biological activity of gastrin-releasing peptide and its receptors in the kidney.

G. Baldwin, A. Shulkes, C. Dumesny, 2004, American journal of physiology. Renal physiology.

Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions.

G. Baldwin, K. M. Marshall, A. Shulkes, 2015, American journal of physiology. Gastrointestinal and liver physiology.

Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo.

B. Kemp, G. Baldwin, O. Patel, 2012, Endocrinology.

Phylogenetic analysis of the sequences of gastrin-releasing peptide and its receptors: Biological implications

G. Baldwin, O. Patel, A. Shulkes, 2007, Regulatory Peptides.

Synthesis, expression and biological activity of the prohormone for gastrin releasing peptide (ProGRP).

G. Baldwin, O. Patel, A. Shulkes, 2006, Endocrinology.

Phosphorylation of gastrin-17 by epidermal growth factor-stimulated tyrosine kinase

G. Baldwin, J. Knesel, J. M. Monckton, 1983, Nature.

Circulating gastrin is increased in hemochromatosis

Kelly A. Smith, G. Baldwin, A. Shulkes, 2006, FEBS letters.

p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways.

G. Baldwin, A. Shulkes, J. Chernoff, 2013, American journal of physiology. Gastrointestinal and liver physiology.

The effects of nonspeciﬁc HIF1 a inhibitors on development of castrate resistance and metastases in prostate cancer

G. Baldwin, O. Patel, A. Shulkes, 2014 .

The effects of nonspecific HIF 1 a inhibitors on development of castrate resistance and metastases in prostate cancer

G. Baldwin, O. Patel, A. Shulkes, 2014 .

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

C. May, G. Baldwin, O. Patel, 2018, BioMetals.

American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte

David M. Pritchard, Michael Camilleri, Gianrico Farrugia, 2003 .

Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin

G. Baldwin, P. Carnegie, 1971, Science.

Quantitative Polymerase Chain Reaction Messenger RNA Levels in Colonic Carcinoma Cell Lines by α Measurement of Gastrin and Transforming Growth Factor Updated

G. Baldwin, Qun Zhang, Graham S. Baldwin, 2006 .

Measurement of gastrin and transforming growth factor alpha messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction.

G. Baldwin, Q. X. Zhang, Graham S. Baldwin, 1992, Cancer research.

Phosphorylation of a synthetic gastrin peptide by the tyrosine kinase of A431 cell membranes.

A. Burgess, B. Kemp, G. Baldwin, 1982, Biochemical and biophysical research communications.

Synthetic peptide substrates for the membrane tyrosine protein kinase stimulated by epidermal growth factor.

B. Kemp, G. Baldwin, C. House, 1984, European journal of biochemistry.

Metformin may offer no protective effect in men undergoing external beam radiation therapy for prostate cancer

G. Baldwin, O. Patel, A. Shulkes, 2019, BJU international.

Biologically Active Recombinant Human Progastrin6–80Contains a Tightly Bound Calcium Ion*

A. Paterson, G. Baldwin, A. Shulkes, 2001, The Journal of Biological Chemistry.

Binding of pepsinogen to the 78 kDa gastrin binding protein.

G. Baldwin, G. Neumann, K. Rorison, 1999, Biochimica et biophysica acta.

Structural requirements for the binding of non-steroidal anti-inflammatory drugs to the 78 kDa gastrin binding protein.

G. Baldwin, K. Rorison, 1999, Biochimica et Biophysica Acta.

Gastrin and gastrin receptor antagonists bind to both N- and C-terminal halves of the 78 kDa gastrin-binding protein.

V. Murphy, G. Baldwin, T. Mantamadiotis, 1996, The international journal of biochemistry & cell biology.

Isolation and partial amino acid sequence of a 78 kDa porcine gastrin-binding protein.

G. Baldwin, M. Rubira, J. Weinstock, 1994, The International journal of biochemistry.

Isolation of transferrin from porcine gastric mucosa: comparison with porcine serum transferrin.

R. Simpson, G. Baldwin, B. Toh, 1990, Comparative biochemistry and physiology. B, Comparative biochemistry.

Binding of gastrin to gastric transferrin

G. Baldwin, J. Weinstock, R. Chandler, 1986, FEBS letters.

Epidermal growth factor induces serine phosphorylation of stathmin in a human colon carcinoma cell line (LIM 1215).

L. D. Ward, R. Moritz, A. Burgess, 1993, The Journal of biological chemistry.

Purification and partial amino acid sequence of annexin V from porcine gastric mucosal membranes.

R. Moritz, R. Simpson, G. Baldwin, 1991, Comparative biochemistry and physiology. B, Comparative biochemistry.

Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine.

G. Baldwin, G. Bramante, A. Shulkes, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Preparation and Properties of Recombinant Rat and Human Procholecystokinin57–95

G. Baldwin, Susann Friedrich, Y. Sims, 2008, The protein journal.

High-resolution proton nuclear magnetic resonance studies of human gastrin.

R. Norton, G. Baldwin, A. Torda, 1985, Biochemistry.

Platelet-derived growth factor induces phosphatidylinositol 3-kinase release from the middle T-pp60c-src complex and association with the platelet-derived growth factor receptor.

G. Baldwin, Q. X. Zhang, 1994, Growth factors.

Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein.

G. Baldwin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells

G. Baldwin, F. Hollande, S. Roche, 2003, Journal of Cell Science.

Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line.

G. Ciccotosto, G. Baldwin, A. Shulkes, 1997, Gastroenterology.

Involvement of Phosphatidylinositol 3-Kinase and Mitogen-activated Protein Kinases in Glycine-extended Gastrin-induced Dissociation and Migration of Gastric Epithelial Cells*

G. Baldwin, F. Hollande, J. Bali, 2001, The Journal of Biological Chemistry.

Binding of Gastrin17 to Human Gastric Carcinoma Cell Lines

G. Baldwin, J. Weinstock, 1988 .

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

C. May, G. Baldwin, O. Patel, 2018, BioMetals.

Rapid purification of the gastric H+/K(+)-ATPase complex by tomato-lectin affinity chromatography.

R. Simpson, G. Baldwin, P. Gleeson, 1992, The Biochemical journal.

Gastrins, iron and colorectal cancer.

G. Baldwin, 2009, Metallomics : integrated biometal science.

Retro-inverso forms of gastrin5–12 are as biologically active as glycine-extended gastrin in vitro but not in vivo

G. Baldwin, I. Sims, K. M. Marshall, 2015, Peptides.

Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.

P. Kiener, G. Baldwin, S. G. Waley, 1980, The Biochemical journal.

A new inhibitor of mitochondrial fatty acid oxidation.

T. Hashimoto, G. Baldwin, M. Souri, 1996, Journal of biochemistry.

High Affinity Binding of Indium and Ruthenium Ions by Gastrins

G. Baldwin, G. George, M. Pushie, 2015, PloS one.

Inactivation of chicken liver pyruvate carboxylase by 1,10-phenanthroline.

J. Carver, G. Baldwin, J. Wallace, 1988, The Biochemical journal.

Do NSAIDs contribute to acute fatty liver of pregnancy?

G. Baldwin, 2000, Medical hypotheses.

Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis

G. Baldwin, C. Dumesny, M. Sandrin, 2017, BMC Cancer.

Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1α and β-catenin via a p-21 activated kinase 1-dependent pathway.

G. Baldwin, A. Shulkes, J. Beutler, 2015, Biochimica et biophysica acta.

The β‐subunit of the gastric H+/K+‐ATPase can occur without the α‐subunit

G. Baldwin, 1990 .

The beta-subunit of the gastric H+/K(+)-ATPase can occur without the alpha-subunit.

G. Baldwin, 1990, FEBS letters.

Ferric Ions Are Essential for the Biological Activity of the Hormone Glycine-extended Gastrin*

R. Norton, G. Baldwin, A. Shulkes, 2002, The Journal of Biological Chemistry.

5‐Demethylretinal and its 5‐2H, 7‐2H2 and 5,7‐2H2 isotopomers. Synthesis, photochemistry and spectroscopy

G. Baldwin, C. Winkel, J. Lugtenburg, 2010 .

Phosphorylation of human growth hormone by the epidermal growth factor-stimulated tyrosine kinase.

R. Simpson, G. Baldwin, M. Hearn, 1983, Proceedings of the National Academy of Sciences of the United States of America.

5-Demethylretinal and Its 5-2H, 7-2H and 5,7-2H2 Isotopomers. Synthesis, Photochemistry and Spectroscopy.

G. Baldwin, C. Winkel, J. Lugtenburg, 1988 .

Gastrins, cholecystokinins and gastrointestinal cancer.

G. Baldwin, A. Shulkes, Arthur Shulkes, 2004, Biochimica et biophysica acta.

Gastrin and the transforming protein of polyoma virus have evolved from a common ancestor

G. Baldwin, 1982, FEBS letters.

Gastrins, iron homeostasis and colorectal cancer.

G. Baldwin, G. Anderson, S. Kovac, 2011, Biochimica et biophysica acta.

CHAPTER 49 – Regulation of Gastric Acid Secretion

G. Baldwin, A. Shulkes, 2006 .

The role of gastrin and cholecystokinin in normal and neoplastic gastrointestinal growth

G. Baldwin, 1995, Journal of gastroenterology and hepatology.

BRIEF REVIEW BIOLOGY OF GUT CHOLECYSTOKININ AND GASTRIN RECEPTORS

G S Baldwin, G. Baldwin, A. Shulkes, 1997, Clinical and experimental pharmacology & physiology.

Comparison of transferrin sequences from different species.

G. Baldwin, 1993, Comparative biochemistry and physiology. B, Comparative biochemistry.

Phosphorylation of cyclin-dependent kinase 2 peptides enhances metal binding.

G. Baldwin, 2009, Biochemical and biophysical research communications.

Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth.

G. Baldwin, A. Shulkes, M. Sandrin, 2009, Biochimica et biophysica acta.

P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1α.

G. Baldwin, O. Patel, A. Shulkes, 2013, Cancer letters.

Evolution of gastrointestinal hormones: the cholecystokinin/gastrin family

G. Baldwin, O. Patel, A. Shulkes, 2010, Current opinion in endocrinology, diabetes, and obesity.

Post-translational Processing of Gastrointestinal Peptides

G. Baldwin, 2012 .

Short term infusion of glycine‐extended gastrin17 stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa

G. Baldwin, A. Shulkes, A. Aly, 2001, International journal of cancer.

Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer.

G. Baldwin, Hong He, M. Nikfarjam, 2019, American journal of physiology. Gastrointestinal and liver physiology.

p21-activated kinases and gastrointestinal cancer.

G. Baldwin, Hong He, 2013, Biochimica et biophysica acta.

Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.

G. Baldwin, A. Shulkes, Hong He, 2008, Cellular signalling.

Identification of a 70-kDa gastrin-binding protein on DLD-1 human colorectal carcinoma cells.

G. Baldwin, A. Shulkes, C. Yang, 2001, The international journal of biochemistry & cell biology.

Binding sites for progastrin‐derived peptides in colonic crypts

G. Baldwin, Y. Karelina, Yulia Karelina, 2001, Journal of gastroenterology and hepatology.

Overexpression of sense or antisense human gastrin mRNA does not affect proliferation of normal rat kidney fibroblasts.

A. Paterson, G. Baldwin, A. Shulkes, 1999, The international journal of biochemistry & cell biology.

Expression of progastrin‐derived peptides and gastrin receptors in a panel of gastrointestinal carcinoma cell lines

G. Baldwin, F. Hollande, April P. Kelly, 1998, Journal of gastroenterology and hepatology.

Molecular cloning and sequence of the ovine gastrin gene.

G. Baldwin, A. Shulkes, C. Moore, 1997, DNA sequence : the journal of DNA sequencing and mapping.

Identification of a gastrin binding protein in porcine gastric mucosal membranes by covalent cross-linking with iodinated gastrin.

G. Baldwin, D. Scanlon, J. Weinstock, 1986, The Journal of biological chemistry.

Zinc ions upregulate the hormone gastrin via an E-box motif in the proximal gastrin promoter.

G. Baldwin, O. Patel, A. Shulkes, 2013, Journal of molecular endocrinology.

Bismuth ions inhibit the biological activity of non-amidated gastrins in vivo.

G. Baldwin, A. Shulkes, S. Loh, 2012, Biochemical pharmacology.

Gastrin-deficient mice have disturbed hematopoiesis in response to iron deficiency.

W. Alexander, G. Baldwin, A. Shulkes, 2011, Endocrinology.

Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor

G. Baldwin, O. Patel, A. Shulkes, 2010, FEBS letters.

Production, secretion, and biological activity of the C-terminal flanking peptide of human progastrin.

Kelly A. Smith, B. Kemp, G. Baldwin, 2006, Gastroenterology.

Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo

G. Baldwin, A. Shulkes, A. Giraud, 2006, Regulatory Peptides.

Identity and regulation of stored and secreted progastrin-derived peptides in sheep.

G. Baldwin, A. Shulkes, G. Neumann, 2004, Endocrinology.

Biological activity and ferric ion binding of fragments of glycine-extended gastrin.

R. Norton, G. Baldwin, B. Shehan, 2004, Biochemistry.

A Novel Effect of Bismuth Ions

R. Norton, G. Baldwin, A. Shulkes, 2004, Journal of Biological Chemistry.

Metabolism of recombinant progastrin in sheep.

G. Baldwin, A. Shulkes, A. Paterson, 2002, American journal of physiology. Endocrinology and metabolism.

Gastrin as an autocrine growth factor in colorectal carcinoma: implications for therapy.

G. Baldwin, A. Shulkes, 1998, World journal of gastroenterology.

Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.

G. Baldwin, G. Lambeau, A. Shulkes, 2007, Gastroenterology.

Demonstration and biological significance of a gastrin‐P21‐activated kinase 1 feedback loop in colorectal cancer cells

G. Baldwin, A. Shulkes, Nhi Huynh, 2014, Physiological reports.

Recombinant C-terminal fragments of the gastrin-releasing peptide precursor are bioactive.

G. Baldwin, O. Patel, A. Shulkes, 2007, Cancer letters.

C-terminal fragments of the gastrin-releasing peptide precursor stimulate cell proliferation via a novel receptor.

G. Baldwin, O. Patel, A. Shulkes, 2007, Endocrinology.

Gut hormones, growth and malignancy.

G. Baldwin, R. Whitehead, 1994, Bailliere's clinical endocrinology and metabolism.

Expression of gastrin, gastrin/CCK-B and gastrin/CCK-C receptors in human colorectal carcinomas

G. Baldwin, T. Mantamadiotis, A. Imdahl, 2005, Journal of Cancer Research and Clinical Oncology.

Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases.

G. Baldwin, A. Shulkes, J. Beutler, 2014, Cancer letters.

Binding of gastrin(17) to human gastric carcinoma cell lines.

G. Baldwin, J. Weinstock, 1988, Cancer research.

p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation

G. Baldwin, Hong He, M. Nikfarjam, 2018, World journal of gastroenterology.

PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines.

M. Pajic, G. Baldwin, Nhi Huynh, 2019, American journal of translational research.

The PAK Inhibitor PF-3758309 Promotes the Inhibitory Effects of Multiple Chemotherapeutic Reagents on Patient-Derived Pancreatic Cancer Cell Lines

M. Pajic, G. Baldwin, Nhi Huynh, 2018 .

Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model

G. Baldwin, J. Beutler, Nhi Huynh, 2016, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers

G. Baldwin, O. Patel, A. Shulkes, 2013, PloS one.

High-performance liquid chromatography of amino acids, peptides and proteins. LVIII. Application of reversed-phase high-performance liquid chromatography to the separation of tyrosine-specific phosphorylated polypeptides related to human growth hormone.

R. Simpson, G. Baldwin, M. Hearn, 1984, Journal of Chromatography A.

Divergent roles for ferric ions in the biological activity of amidated and non-amidated gastrins.

G. Baldwin, A. Shulkes, J. Pannequin, 2004, The Journal of endocrinology.

Comparison of Two Syngeneic Orthotopic Murine Models of Pancreatic Adenocarcinoma

G. Baldwin, C. Christophi, Hong He, 2013, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

Quantitative measurement of mRNA coding for the receptors controlling acid secretion in the ovine fundus and antrum by using RT‐PCR

G. Baldwin, A. Shulkes, S. Kolivas, 2000, Journal of gastroenterology and hepatology.

A spectroscopic study of metal ion and ligand binding to β-lactamase II

G. Baldwin, S. G. Waley, H. Hill, 1980 .

CCK receptors and cancer.

G. Baldwin, A. Shulkes, 2007, Current topics in medicinal chemistry.

Expression of gastrin, gastrin/CCK-B- and gastrin/CCK-C. Receptors in human colorectal carcinomas

G. Baldwin, A. Imdahl, E. Farthmann, 1995 .

Expression and function of gastrin‐releasing peptide (GRP) in normal and cancerous urological tissues

G. Baldwin, O. Patel, A. Shulkes, 2014, BJU international.

Definition of the residues required for the interaction between glycine‐extended gastrin and transferrin in vitro

A. Mason, G. Baldwin, J. Estève, 2009, The FEBS journal.

Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic

G. Baldwin, O. Patel, D. Bolton, 2019, Journal of Nephrology.

A new role for an old hormone: is gastrin a cofactor for dietary metal ion uptake?

G. Baldwin, 1992, Medical hypotheses.

Metal ion-dependent binding of gastrin to albumin.

G. Baldwin, G. Howlett, R. Mann, 1991, Archives of biochemistry and biophysics.

Interaction of gastrin with transferrin: effects of ferric ions.

G. Baldwin, G. Howlett, J. Knesel, 1988, Archives of biochemistry and biophysics.

The effects of nonspecific HIF1α inhibitors on development of castrate resistance and metastases in prostate cancer

G. Baldwin, O. Patel, A. Shulkes, 2014, Cancer medicine.

Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway.

G. Baldwin, A. Shulkes, J. Pannequin, 2005, American journal of physiology. Gastrointestinal and liver physiology.

Signaling the Junctions in Gut Epithelium

G. Baldwin, A. Shulkes, F. Hollande, 2005, Science's STKE.

Binding of a valproate metabolite to the trifunctional protein of fatty acid oxidation

H. Nau, G. Baldwin, Frank S. Abbott, 1996, FEBS letters.

HIF1α expression under normoxia in prostate cancer--which pathways to target?

G. Baldwin, O. Patel, A. Shulkes, 2015, The Journal of urology.

Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis

G. Baldwin, C. Dumesny, M. Sandrin, 2017, BMC Cancer.

Zinc Preconditioning Provides Cytoprotection following Iodinated Contrast Media Exposure in In Vitro Models

G. Baldwin, O. Patel, A. Shulkes, 2021, Contrast media & molecular imaging.

The role of p21-activated kinases in pancreatic cancer.

G. Baldwin, M. Nikfarjam, D. Yeo, 2015, Pancreas.

P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.

G. Baldwin, A. Shulkes, C. Christophi, 2012, Cancer letters.

FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine

G. Baldwin, A. Lowy, O. Patel, 2016, BMC Cancer.

Experimental rat models for contrast-induced nephropathy; a comprehensive review

G. Baldwin, O. Patel, A. Shulkes, 2020, Journal of Nephropathology.

Oral trivalent bismuth ions decrease, and trivalent indium or ruthenium ions increase, intestinal tumor burden in ApcΔ14/+ mice.

G. Baldwin, K. M. Marshall, C. Dumesny, 2018, Metallomics : integrated biometal science.

Progastrin: a potential predictive marker of liver metastasis in colorectal cancer

G. Baldwin, O. Patel, A. Shulkes, 2017, International Journal of Colorectal Disease.

The seventh transmembrane domain of gastrin/CCK receptors contributes to non-peptide antagonist binding.

G. Baldwin, T. Mantamadiotis, 1994, Biochemical and biophysical research communications.

Mutation of Lysine Residues of the 78-kDa Gastrin-Binding Protein Reduces Gastrin Binding

G. Baldwin, K. Rorison, Debra J. Lee, 2001, Journal of protein chemistry.

More about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

G. Baldwin, A. Shulkes, F. Macrae, 2000, Journal of the National Cancer Institute.

Binding of progastrin fragments to the 78 kDa gastrin‐binding protein

G. Baldwin, 1995, FEBS letters.

PCR cloning and sequence of gastrin mRNA from carcinoma cell lines.

G. Baldwin, T. Mantamadiotis, K. Mcbride, 1990, Biochemical and biophysical research communications.

Properties of the Complex Between Recombinant Human Progastrin and Ferric Ions

G. Baldwin, 2004, The Protein Journal.

Selective, high-affinity binding of ferric ions by glycine-extended gastrin(17).

G. Baldwin, W. Sawyer, C. Curtain, 2001, Biochemistry.

Factors that influence the translocation of the N-carboxybiotin moiety between the two sub-sites of pyruvate carboxylase.

G. Goodall, G. Baldwin, J. Wallace, 1981, The Biochemical journal.

PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins.

G. Baldwin, A. Shulkes, Graham S. Baldwin, 2008, Biochimica et biophysica acta.

Zinc Ions Mediate Gastrin Expression, Proliferation, and Migration Downstream of the Cholecystokinin-2 Receptor.

G. Baldwin, O. Patel, A. Shulkes, 2016, Endocrinology.

Chapter 165 – Gastrin

G. Baldwin, A. Shulkes, 2013 .

Developmental expression and biological activity of gastrin-releasing peptide ( GRP ) and GRP receptors in the kidney

G. Baldwin, A. Shulkes, C. Dumesny, 2004 .

Identification of binding sites for C‐terminal pro‐gastrin‐releasing peptide (GRP)‐derived peptides in renal cell carcinoma: a potential target for future therapy

Damien Bolton, Joseph Ischia, K. Sethi, 2015, BJU international.

G. Baldwin, Q. X. Zhang, 1993, Trends in biochemical sciences.

Calcium Binds Dynamin I and Inhibits Its GTPase Activity

G. Baldwin, P. Robinson, Jun-Ping Liu, 1996, Journal of neurochemistry.

Preparation of Biologically Active Recombinant Human Progastrin1–80

G. Baldwin, A. Shulkes, J. Pannequin, 2002, Journal of protein chemistry.

Comparison of sequences of the 78 kDa gastrin-binding protein and some enzymes involved in fatty acid oxidation.

G. Baldwin, 1993, Comparative biochemistry and physiology. B, Comparative biochemistry.

Comparison of sequence of the 78 kDa gastrin-binding protein and some enzymes involved in fatty acid oxidation

G. Baldwin, 1993 .

Rho GTPases and p21-activated kinase in the regulation of proliferation and apoptosis by gastrins.

G. Baldwin, Hong He, 2008, The international journal of biochemistry & cell biology.

Comparison of iodinated [Nle15]- and [Met15]-gastrin17 prepared by reversed-phase HPLC.

E. Nice, L. Fabri, G. Baldwin, 1987, Biomedical chromatography : BMC.

Structures of the human cDNA and gene encoding the 78 kDa gastrin-binding protein and of a related pseudogene.

G. Baldwin, Q. X. Zhang, 1994, Biochimica et biophysica acta.

The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a beta subunit of the gastric H+/K(+)-ATPase (proton pump).

R. Moritz, R. Simpson, G. Baldwin, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of porcine liver transferrin.