D. Groebe

发表

Screening for positive allosteric modulators of biological targets.

D. Groebe, 2006, Drug discovery today.

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates.

O. Uhlenbeck, D. Groebe, J. Milligan, 1987, Nucleic acids research.

Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.

Hua Tang, Bo Liu, Gang Liu, 2011, ACS chemical biology.

In search of negative allosteric modulators of biological targets.

D. Groebe, 2009, Drug discovery today.

Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α.

P. Hajduk, S. Swann, Chaohong Sun, 2010, Bioorganic & medicinal chemistry letters.

Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle.

U. Warrior, D. Burns, D. Groebe, 2002, Journal of Pharmacology and Experimental Therapeutics.

alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity.

D. Groebe, J. McIntosh, B. Olivera, 1995, Biochemistry.

Chemical syntheses and biological activities of lactam analogues of α-conotoxin SI

D. Groebe, N. Solé, G. Bárány, 2000 .

A Better Way to Make RNA for Physical Studies

O. Uhlenbeck, D. Groebe, J. Milligan, 1986 .

Evaluation of Electrochemiluminescent Technology for Inhibitors of Granulocyte Colony-Stimulating Factor Receptor Binding

U. Warrior, D. Burns, D. Groebe, 2000, Journal of biomolecular screening.

CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes.

G. Stormo, M. Gayle, I. Tinoco, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Determinants involved in the affinity of alpha-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors.

D. Groebe, W. Gray, S. Abramson, 1997, Biochemistry.

Cationic lipid-mediated co-transfection of insect cells

Chien Ho, D. R. Groebe, A. E. Chung, 1990, Nucleic Acids Res..

Lophotoxin Is a Slow Binding Irreversible Inhibitor of Nicotinic Acetylcholine Receptors (*)

D. Groebe, S. Abramson, 1995, The Journal of Biological Chemistry.

Validation of FLIPR Membrane Potential Dye for High Throughput Screening of Potassium Channel Modulators

Sujatha M. Gopalakrishnan, Char-Chang Shieh, U. Warrior, 2001, Journal of biomolecular screening.

Functional analysis of large conductance Ca2(+)-activated K(+) channels: ion flux studies by atomic absorption spectrometry.

U. Warrior, C. Shieh, D. Groebe, 2003, Assay and drug development technologies.

Screening for inhibitors of histone deacetylase by incorporating a spraying method to micro-arrayed compound screening.

K. Glaser, U. Warrior, D. Burns, 2004, Combinatorial chemistry & high throughput screening.

High-level production of human a- and -globins in insect cells

M. Busch, S. Liebhaber, D. Groebe, 1992 .

alpha-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors.

D. Groebe, E. Levitan, E S Levitan, 1995, Molecular pharmacology.

Irreversible inhibition of nicotinic acetylcholine receptors by the bipinnatins. Toxin activation and kinetics of receptor inhibition.

D. Groebe, S. Abramson, J. Dumm, 1994, The Journal of biological chemistry.

Characterization of RNA hairpin loop stability.

O. Uhlenbeck, D. Groebe, O C Uhlenbeck, 1988, Nucleic acids research.

Chemical syntheses and biological activities of lactam analogues of alpha-conotoxin SI.

D. Groebe, N. Solé, B. Hargittai, 2000, Journal of medicinal chemistry.

Putting Thought to Paper: A μARCS Protease Screen

U. Warrior, D. Burns, D. Groebe, 2003 .

Thermal stability of RNA hairpins containing a four-membered loop and a bulge nucleotide.

O. Uhlenbeck, D. Groebe, O C Uhlenbeck, 1989, Biochemistry.