S. Lazareno

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Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.

S. Lazareno, N. Birdsall, N J Birdsall, 1995, Molecular pharmacology.

Estimation ofcompetitive antagonist affinity fromfunctional inhibition curves using theGaddum,Schild andCheng-Prusoff equations

S. Lazareno, 1993 .

Pharmacological characterization of acetylcholine‐stimulated [35S]‐GTPγS binding mediated by human muscarinic m1–m4 receptors: antagonist studies

S. Lazareno, N. Birdsall, N. Birdsall, 1993, British journal of pharmacology.

Estimation of competitive antagonist affinity from functional inhibition curves using the Gaddum, Schild and Cheng‐Prusoíf equations

S. Lazareno, N. Birdsall, S. Lazareno, 1993, British journal of pharmacology.

Functional and binding studies with muscarinic M2‐subtype selective antagonists

S. Lazareno, F. Roberts, 1989, British journal of pharmacology.

Allosteric Regulation of Binding and Function at GCPRS

S. Lazareno, N. Birdsall, C. Browning, 2004, Medicinal Chemistry Research.

Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors m1-m4.

S. Lazareno, N. Birdsall, T. Farries, 1993, Life sciences.

To What Extent Can Binding Studies Allow the Quantification of Affinity and Efficacy?

S. Lazareno, N. Birdsall, N. Birdsall, 1997, Annals of the New York Academy of Sciences.

Measurement of Agonist-Stimulated [ 35 S]GTPγS Binding to Cell Membranes

S. Lazareno, 1997 .

Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells.

S. Lazareno, N. Buckley, F. Roberts, 1990, Molecular pharmacology.

Cholinergic treatments for Alzheimer's disease.

S. Lazareno, F. Roberts, 1989, Biochemical Society transactions.

Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors.

S. Lazareno, N. Birdsall, P. Gharagozloo, 1999, Journal of medicinal chemistry.

Allosteric interactions between the antagonist prazosin and amiloride analogs at the human alpha(1A)-adrenergic receptor.

S. Lazareno, N. Birdsall, R. Leppik, 2000, Molecular pharmacology.

Muscarinic interactions of bisindolylmaleimide analogues.

S. Lazareno, N. Birdsall, A. Popham, 1998, European journal of pharmacology.

Chapter 12 Allosteric regulation of muscarinic receptors

S. Lazareno, H. Matsui, N. Birdsall, 1996 .

Quantitation of allosteric interactions.

S. Lazareno, N. Birdsall, 1996, Trends in pharmacological sciences.

Characterization of the allosteric interactions between antagonists and amiloride analogues at the human alpha2A-adrenergic receptor.

S. Lazareno, N. Birdsall, R. Leppik, 1998, Molecular pharmacology.

Multiple allosteric sites on muscarinic receptors.

J. Saldanha, S. Lazareno, N. Birdsall, 2001, Life sciences.

Allosteric regulation of muscarinic receptors.

S. Lazareno, N. Birdsall, H. Matsui, 1996, Progress in brain research.

Sobs Annual Report | | 2008 80 Primary

J. Whisstock, P. Taylor, L. Poston, 2022 .

Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity.

S. Lazareno, N. Birdsall, A. Popham, 2004, Molecular pharmacology.

Reduction in Muscarinic M1-Mediated Hypercholinergic State and Beneficial Cognitive Effects of Muscarinic Agonists in Schizophrenia

F. Bymaster, D. McKinzie, S. Lazareno, 2009 .

Allosteric regulation of G-protein-linked receptors.

S. Lazareno, N. Birdsall, H. Matsui, 1995, Biochemical Society transactions.

Effects of contamination on radioligand binding parameters.

S. Lazareno, N. Birdsall, 2000, Trends in pharmacological sciences.

The effects of saponin on the binding and functional properties of the human adenosine A1 receptor

S. Lazareno, N. Birdsall, N. Birdsall, 1996, British journal of pharmacology.

The affinity of adenosine for the high- and low-affinity states of the human adenosine A1 receptor.

S. Lazareno, N. Birdsall, F. Cohen, 1996, European journal of pharmacology.

Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors

S. Lazareno, N. Birdsall, A. Popham, 2007, Journal of Molecular Neuroscience.

Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors.

S. Lazareno, N. Birdsall, S Lazareno, 2002, Molecular pharmacology.

Allosterism at muscarinic receptors: ligands and mechanisms.

S. Lazareno, N. Birdsall, 2005, Mini reviews in medicinal chemistry.

Subtype-selective positive cooperative interactions between brucine analogs and acetylcholine at muscarinic receptors: functional studies.

S. Lazareno, N. Birdsall, P. Gharagozloo, 1999, Molecular pharmacology.

Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism

S. Lazareno, D. Kendall, S. Nahorski, 1985, Neuropharmacology.

Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes.

S. Lazareno, N. Birdsall, P. Gharagozloo, 1997, Life sciences.

Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site.

S. Lazareno, N. Birdsall, A. Popham, 2000, Molecular pharmacology.

Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.

S. Lazareno, N. Birdsall, P. Gharagozloo, 1998, Molecular pharmacology.

Measuring muscarinic antagonist potency using stimulated phosphoinositide breakdown in rat cortex slices

S. Lazareno, F. Roberts, 1987 .

Estimation of antagonist Kb from inhibition curves in functional experiments: alternatives to the Cheng-Prusoff equation.

S. Lazareno, N. Birdsall, N J Birdsall, 1993, Trends in pharmacological sciences.

Effects of GTP on 3H-domperidone binding and its displacement by dopamine in rat striatal homogenates.

S. Lazareno, 1983, Journal of receptor research.

Measurement of Competitive and Allosteric Interactions in Radioligand Binding Studies

S. Lazareno, 2019, G Protein-Coupled Receptors.

QUANTIFICATION OF RECEPTOR INTERACTIONS USING BINDING METHODS

S. Lazareno, 2001, Journal of receptor and signal transduction research.

Effect of lead exposure on dopaminergic D2 receptor binding in the 21-day-old rat.

S. Lazareno, C. Winder, 1985, Toxicology letters.

GraphPad Prism (version 1.02): produced by GraphPad Softioare Inc. 10855 Sorrento Valley Road, Suite 203, San Diego, CA 92121 USA, 1993. $445.00 (for universities)/$371.25 (for students)/$495.00 (for others)

S. Lazareno, 1994 .

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

A. Christopoulos, F. Bymaster, D. McKinzie, 2008, Proceedings of the National Academy of Sciences.

Selective labelling of dopamine (D2) receptors in rat striatum by [3H]domperidone but not by [3H]spiperone.

S. Lazareno, S. Nahorski, 1982, European journal of pharmacology.

Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis.

S. Lazareno, N. Birdsall, H. Matsui, 1995, Molecular pharmacology.

Differential effects of selective and non-selective neuroleptics on intracellular and extracellular cyclic AMP accumulation in rat striatal slices

S. Lazareno, S. Nahorski, D. Marriott, 1985, Brain Research.

d-Amphetamine and punished responding: The role of catecholamines and anorexia

S. Lazareno, 1979, Psychopharmacology.

Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

Gregory I. Mashanov, Justin E. Molloy, S. Lazareno, 2010, Proceedings of the National Academy of Sciences.

Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.

S. Lazareno, N. Birdsall, P. Gharagozloo, 1999, Life Science.

Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.

K. Mohr, S. Lazareno, C. Tränkle, 2003, Molecular pharmacology.

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

A. Christopoulos, D. McKinzie, S. Lazareno, 2008, Proceedings of the National Academy of Sciences.