H. Bosshard

发表

Antigen recognition by conformational selection

A. Plückthun, C. Berger, S. Weber-Bornhauser, 1999, FEBS letters.

Protein stabilization by salt bridges: concepts, experimental approaches and clarification of some misunderstandings

H. Bosshard, I. Jelesarov, D. Marti, 2004, Journal of molecular recognition : JMR.

Calculation of protein ionization equilibria with conformational sampling: pKa of a model leucine zipper, GCN4 and barnase

Amedeo Caflisch, Hans Rudolf Bosshard, A. Caflisch, 2002, Proteins.

Fabricating microarrays of functional proteins using affinity contact printing.

E. Delamarche, André Bernard, D. Juncker, 2002, Angewandte Chemie.

Spectroscopic, calorimetric, and kinetic demonstration of conformational adaptation in peptide-antibody recognition.

C. Berger, H. Bosshard, I. Jelesarov, 1995, Biochemistry.

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system.

A. Plückthun, A. Honegger, H. Bosshard, 1997, Journal of immunological methods.

Fabricating arrays of single protein molecules on glass using microcontact printing

Urs P. Wild, Emmanuel Delamarche, Bert Hecht, 2003 .

Affinity capture of proteins from solution and their dissociation by contact printing

Peter Sonderegger, Emmanuel Delamarche, Hans Rudolf Bosshard, 2001, Nature Biotechnology.

Thermodynamic characterization of the coupled folding and association of heterodimeric coiled coils (leucine zippers).

H. Bosshard, I. Jelesarov, H R Bosshard, 1996, Journal of molecular biology.

Microcontact Printing of Proteins

Emmanuel Delamarche, Hans Rudolf Bosshard, E. Delamarche, 2000 .

Binding and oxidation of mutant cytochromes c by cytochrome‐c oxidase

H. Bosshard, A. Mauk, B. Michel, 1989, FEBS letters.

Ferredoxin binding site on ferredoxin: NADP+ reductase. Differential chemical modification of free and ferredoxin-bound enzyme.

W. Koppenol, H. Bosshard, I. Jelesarov, 1993, European journal of biochemistry.

Comparison of the binding sites of plant ferredoxin for two ferredoxin‐dependent enzymes

P. Schürmann, H. Bosshard, H. Bosshard, 1994, FEBS letters.

Very rapid, ionic strength-dependent association and folding of a heterodimeric leucine zipper.

A. Baici, H. Bosshard, I. Jelesarov, 1997, Biochemistry.

A new method for the synthesis of optically active -amino acids and their N derivatives via acylamino malonates.

H. Bosshard, A. Berger, N. Kurn, 1973, The Journal of organic chemistry.

The topographical differences in the active site region of alpha-chymotrypsin, subtilisin Novo, and subtilisin Carlsberg. Mapping the aromatic binding site by inhibitors (virtual substrates).

H. Bosshard, A. Berger, 1974, Biochemistry.

Kinetic evidence for two different productive substrate binding sites in subtilisins

H. Bosshard, 1973, FEBS letters.

Oxidation of cytochrome c by cytochrome c oxidase: spectroscopic binding studies and steady-state kinetics support a conformational transition mechanism.

H. Bosshard, B. Michel, 1989, Biochemistry.

Extremely fast folding of a very stable leucine zipper with a strengthened hydrophobic core and lacking electrostatic interactions between helices.

H. Bosshard, I. Jelesarov, E. Dürr, 1999, Biochemistry.

Mass spectrometric approaches to molecular characterization of protein-nucleic acid interactions.

M. Glocker, S. Nock, H. Bosshard, 1995, Toxicology letters.

Binding of ferredoxin to ferredoxin: NADP+ oxidoreductase: The role of carboxyl groups, electrostatic surface potential, and molecular dipole moment

W. Koppenol, H. Bosshard, I. Jelesarov, 1993, Protein science : a publication of the Protein Society.

Spectroscopic analysis of the cytochrome c oxidase-cytochrome c complex: circular dichroism and magnetic circular dichroism measurements reveal change of cytochrome c heme geometry imposed by complex formation.

H. Bosshard, B. Michel, C. Weber, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of the binding sites on cytochrome c for cytochrome c oxidase, cytochrome bc1, and cytochrome c1. Differential acetylation of lysyl residues in free and complexed cytochrome c.

H. Bosshard, R. Rieder, 1980, The Journal of biological chemistry.

Mechanism of assembly of a leucine zipper domain

A. Baici, H. Bosshard, H. Wendt, 1994 .

Spectroscopic analysis of the interaction between cytochrome c and cytochrome c oxidase.

H. Bosshard, B. Michel, 1984, The Journal of biological chemistry.

Salt bridges destabilize a leucine zipper designed for maximized ion pairing between helices.

J. Warwicker, A. Gorfe, H. Bosshard, 2002, Biochemistry.

Cytochrome bc 1 and cytochrome oxidase can bind to the same surface domain of the cytochrome c molecule

H. Bosshard, R. Rieder, Rainer Rieder, 1978, FEBS letters.

Aromatic Acids in Urine of Healthy Infants, Persistent Hyperphenylalaninemia, and Phenylketonuria, before and after Phenylalanine Load

H. Bosshard, M. Müller, H. Curtius, 1974, Pediatric Research.

Monomeric and dimeric bZIP transcription factor GCN4 bind at the same rate to their target DNA site.

A. Baici, C. Berger, H. Bosshard, 2004, Biochemistry.

Direct characterization of supramolecular complexes of polypeptides and proteins by electrospray mass spectrometry

M. Glocker, C. Borchers, H. Bosshard, 1995 .

Characterization of leucine zipper complexes by electrospray ionization mass spectrometry

H. Bosshard, M. Przybylski, H. Wendt, 1995, Protein science : a publication of the Protein Society.

Aminoacyl-tRNA synthetases from Bacillus stearothermophilus. Asymmetry of substrate binding to tyrosyl-tRNA synthetase.

H. Bosshard, B. Hartley, L. E. Koch, 1975, European journal of biochemistry.

Stabilization of Type-I .beta.-Turn Conformations in Peptides Containing the NPNA-Repeat Motif of the Plasmodium falciparum Circumsporozoite Protein by Substituting Proline for (S)-.alpha.-Methylproline

John A. Robinson, C. Schiffer, W. F. Gunsteren, 1995 .

Dimethyl-Maleic Anhydride, A New Synthesis and Versatile Uses of an Old Compound

M. Baumann, H. Bosshard, 1979 .

Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition

H. Bosshard, I. Jelesarov, Ilian Jelesarov, 1999, Journal of molecular recognition : JMR.

Potassium tert-butoxide. Strong base for the nonaqueous visual titration of weak acids

H. Bosshard, S. Ehrlich-Rogozinski, 1973 .

Sulfite oxidase from chicken liver. Further characterization of the role of carboxyl groups in the reaction with cytochrome c.

H. Bosshard, M. Ritzmann, 1988, European journal of biochemistry.

Crosslinking of cytochrome c to peroxidase: covalent complex catalyzes oxidation of cytochrome c 1 by H2O2

H. Bosshard, R. Bechtold, B. Waldmeyer, 1980, FEBS letters.

Salt effects on hydrophobic interaction and charge screening in the folding of a negatively charged peptide to a coiled coil (leucine zipper).

H. Bosshard, I. Jelesarov, R. Thomas, 1998, Biochemistry.

The cytochrome c oxidase-cytochrome c complex: spectroscopic analysis of conformational changes in the protein-protein interaction domain.

H. Bosshard, A. Proudfoot, C. Wallace, 1989, Biochemistry.

Methionine-oxidized horse heart cytochromes c. I. Reaction with Chloramine-T, products, and their oxidoreduction properties

H. Bosshard, J. Pande, B. C. Verma, 1987 .

Guided by electrostatics, a textbook protein comes of age

E. Margoliash, H. Bosshard, 1983 .

Caveats for the use of surface-adsorbed protein antigen to test the specificity of antibodies.

H. Bosshard, C. Schwab, 1992, Journal of immunological methods.

Binding site on Rhodospirillum rubrum cytochrome c2 for the Rhodospirillum rubrum cytochrome bc1 complex

H. Bosshard, R. Wynn, D. Knaff, 1987 .

Interaction of horse cytochromec with the photosynthetic reaction center ofRhodospirillum rubrum

H. Bosshard, R. Bachofen, M. Snozzi, 1987 .

Synthesis of Optically Active, Ring-Substituted N-Benzyloxycarbonylphenylalanines via 2-Benzyloxycarbonylamino-2-arylalkylmalonates†

H. Bosshard, A. Berger, 1973 .

Compulsory Order of Substrate Binding to Herpes Simplex Virus Type 1 Thymidine Kinase

G. Folkers, L. Scapozza, H. Bosshard, 2000, The Journal of Biological Chemistry.

Determination of potassium ion concentration in serum using a highly selective liquid-membrane electrode.

H. Bosshard, W. Simon, L. Pioda, 1970, Clinica chimica acta; international journal of clinical chemistry.

Thermodynamics of ferredoxin binding to ferredoxin:NADP+ reductase and the role of water at the complex interface.

H. Bosshard, I. Jelesarov, 1994, Biochemistry.

A new method for the detection of racemization during peptide synthesis: stereoselective hydrolysis of diastereomeric peptides by leucine aminopeptidase.

H. Bosshard, A. Berger, I. Schechter, 1973, Helvetica chimica acta.

Folding of a designed simple ankyrin repeat protein

A. Plückthun, H. Binz, M. Stumpp, 2004, Protein science : a publication of the Protein Society.

Structure of an electron transfer complex. II. Chemical modification of carboxyl groups of cytochrome c peroxidase in presence and absence of cytochrome c.

H. Bosshard, R. Bechtold, 1985, The Journal of biological chemistry.

Structure of an electron transfer complex. I. Covalent cross-linking of cytochrome c peroxidase and cytochrome c.

H. Bosshard, B. Waldmeyer, 1985, The Journal of biological chemistry.

The cytochrome c peroxidase.cytochrome c electron transfer complex. Experimental support of a hypothetical model.

T. Poulos, H. Bosshard, R. Bechtold, 1982, The Journal of biological chemistry.

The cytochrome c oxidase binding site on cytochrome c. Differential chemical modification of lysine residues in free and oxidase-bound cytochrome c.

H. Bosshard, R. Rieder, 1978, The Journal of biological chemistry.

Epitope mapping by chemical modification of free and antibody-bound protein antigen.

H. Binz, H. Bosshard, S. Demotz, 1987, Science.

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.

A. Plückthun, S. Weber-Bornhauser, J. Hanes, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Ca2(+)-binding site of carp parvalbumin recognized by monoclonal antibody.

C. Heizmann, H. Bosshard, M. Oertle, 1990, Cell calcium.

Mapping of four discontiguous antigenic determinants on horse cytochrome c.

H. Bosshard, Y. Paterson, M. Oertle, 1989, European journal of biochemistry.

Monoclonal antibody recognizes a conformational epitope in a random coil protein.

H. Bosshard, G. Corradin, B. Saad, 1988, European journal of biochemistry.

Electrostatic interactions in leucine zippers: thermodynamic analysis of the contributions of Glu and His residues and the effect of mutating salt bridges.

H. Bosshard, D. Marti, 2003, Journal of molecular biology.

Preparation and Properties of Cyanoethylated Insulin

H. Bosshard, K. H. Jørgensen, R. Humbel, 1969 .

Mapping of contact areas in protein-nucleic acid and protein-protein complexes by differential chemical modification.

H. Bosshard, 1979, Methods of biochemical analysis.

Mapping antibody binding sites on cytochrome c with synthetic peptides: Are results representative of the antigenic structure of proteins?

G. Brayer, H. Bosshard, T. P. Lo, 1993, Protein science : a publication of the Protein Society.

Epitope mapping employing immobilized synthetic peptides. How specific is the reactivity of these peptides with antiserum raised against the parent protein?

H. Bosshard, R. Savoca, C. Schwab, 1991, Journal of immunological methods.

11 – Epitope Mapping with Peptides

H. Bosshard, 1995 .

The conformation of cytochrome c in solution. Localization of a conformational difference between ferri- and ferrocytochrome c on the surface of the molecule.

H. Bosshard, M. Zuerrer, 1980, The Journal of biological chemistry.

Concurrent Association and Folding of Small Oligomeric Proteins

H. Bosshard, 2008 .

The cytochrome c peroxidase-cytochrome c electron transfer complex. The role of histidine residues.

T. Poulos, H. Bosshard, T. Hasler, 1984, The Journal of biological chemistry.

Mechanism of monoclonal antibody inhibition/stimulation of reactions catalyzed by cytochrome P450IIB1.

H. Bosshard, M. Péter, M. Oertle, 1991, Archives of biochemistry and biophysics.

Real-time monitoring of antigen-antibody recognition on a metal oxide surface by an optical grating coupler sensor.

H. Bosshard, H R Bosshard, A Bernard, 1995, European journal of biochemistry.

Enthalpic and entropic effects of salt and polyol osmolytes on site-specific protein-DNA association: the integrase Tn916-DNA complex.

Stoyan Milev, Hans Rudolf Bosshard, H. Bosshard, 2005, Biochemistry.

Sulfite oxidase from chicken liver. The role of imidazole and carboxyl groups for the reaction with cytochrome c.

H. Bosshard, M. Ritzmann, Martin Ritzmann, 1986, European journal of biochemistry.

Kinetics of folding of leucine zipper domains.

A. Baici, C. Berger, H. Bosshard, 1995, Biochemistry.

Fast folding of the HIV-1 and SIV gp41 six-helix bundles.

H. Bosshard, Min Lu, I. Jelesarov, 2004, Journal of molecular biology.

The aminoacyl-tRNA synthetase-tRNA complex: detection by differential labelling of lysine residues involved in complex formation.

H. Bosshard, G. Koch, B. Harley, 1978, Journal of molecular biology.

Thermodynamics and kinetics of the reaction of a single-chain antibody fragment (scFv) with the leucine zipper domain of transcription factor GCN4.

C. Berger, S. Weber-Bornhauser, J. Eggenberger, 1998, Biochemistry.

Disulfide formation and stability of a cysteine-rich repeat protein from Helicobacter pylori.

P. Mittl, H. Bosshard, I. Jelesarov, 2006, Biochemistry.

A monoclonal antibody induces opening of a coiled coil. Global protection of amide protons from H/D exchange decreases by up to 1000-fold in antibody-bound triple-stranded coiled coil.

H. Bosshard, E. Dürr, 1997, European journal of biochemistry.

Theories of enzyme specificity and their application to proteases and aminoacyl-Transfer RNA synthetases

H. Bosshard, 1976, Experientia.

Alkaline isomerization of ferricytochrome c: lysine is not replacing methionine at the sixth co-ordination site of the haem iron.

H. Bosshard, 1981, Journal of molecular biology.

Binding of d‐Amino Acid Residues to the Aromatic Binding Sites of α‐Chymotrypsin, Subtilisin Novo and Subtilisin Carlsberg

H. Bosshard, 1974 .

The interaction of D‐Amino acid residues with the aromatic binding site of α‐chymotrypsin

H. Bosshard, 1974 .

Association and Folding of Small Oligomeric Proteins

H. Bosshard, 2008 .

Molecular recognition by induced fit: how fit is the concept?

H. Bosshard, H. Bosshard, H R Bosshard, 2001, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

Energetics of Site‐Specific DNA Recognition by Integrase Tn916

H. Bosshard, I. Jelesarov, Stoyan Milev, 2005 .

Genuine and apparent cross-reaction of polyclonal antibodies to proteins and peptides.

H. Bosshard, I. Jelesarov, L. Leder, 1994, European journal of biochemistry.

Inverse electrostatic effect: electrostatic repulsion in the unfolded state stabilizes a leucine zipper.

H. Bosshard, D. Marti, 2004, Biochemistry.

Energetics of sequence-specific protein-DNA association: binding of integrase Tn916 to its target DNA.

Stoyan Milev, Hans Rudolf Bosshard, Andrey Karshikoff, 2003, Biochemistry.

Binding of cytochrome c to the cytochrome bc1 complex (complex III) and its subunits cytochrome c1 and b1.

H. Schägger, H. Bosshard, G. von Jagow, 1979, Biochemical and biophysical research communications.

Protein A antibody-capture ELISA (PACE): an ELISA format to avoid denaturation of surface-adsorbed antigens.

H. Bosshard, H. Wendt, F. Ackermann, 1993, Journal of immunological methods.

Energetics of coiled coil folding: the nature of the transition states.

H. Bosshard, I. Jelesarov, H R Bosshard, 2001, Biochemistry.

Recombinant wild-type and mutant complexes of ferredoxin and ferredoxin:NADP+ reductase studied by isothermal titration calorimetry.

H. Bosshard, G. Zanetti, L. Piubelli, 1997, Biological chemistry.

Folding of a three–stranded coiled coil

H. Bosshard, E. Dürr, 2000, Protein science : a publication of the Protein Society.