N. Drinkwater

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Mutations in Protein-Binding Hot-Spots on the Hub Protein Smad3 Differentially Affect Its Protein Interactions and Smad3-Regulated Gene Expression

Michael A. Newton, Steven J. Darnell, M. Newton, 2011, PloS one.

The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility.

N. Drinkwater, J. Bugni, T. M. Poole, 2001, Carcinogenesis.

Cloning, chromosomal location, and characterization of mouse E2F1

P. Farnham, W. Kaelin, N. Drinkwater, 1994, Molecular and cellular biology.

Quantitative Comparison of Initiation and Mutation Phenotypes in Hepatocytes of the Analbuminemic Rat

Y. Dragan, N. Drinkwater, A. Koleske, 1993, Japanese journal of cancer research : Gann.

The N-HydroxyMetabolites of N-Methyl-4-aminoazobenzeneand Related Dyes as Proximate Carcinogensin the Rat and Mouse1

H. Pitot, N. Drinkwater, F. Kadlubar, 1979 .

The Long Path from QTL to Gene

N. Drinkwater, M. Gould, 2012, PLoS genetics.

Mechanisms of Carcinogenesis

N. Drinkwater, B. Sugden, 1982 .

Cloning, chromosomal location, and characterization of mouse E2F1

P. Farnham, W. Kaelin, N. Drinkwater, 1994 .

Mutational specificities of 1'-acetoxysafrole, N-benzoyloxy-N-methyl-4-aminoazobenzene, and ethyl methanesulfonate in human cells.

N. Drinkwater, C. A. Ingle, C. Ingle, 1989, Mutation research.

The Hcs7 Mouse Liver Cancer Modifier Maps to a 3.3 Mb Region Carrying the Strong Candidate Ifi202b

N. Drinkwater, A. Schneider, Elizabeth C Poli, 2012 .

2 The Hcs 7 Mouse Liver Cancer Modifier Maps to a 3 . 3 Mb Region Carrying the Strong Candidate Ifi 202 b

N. Drinkwater, A. Schneider, Elizabeth C Poli, 2012 .

The Interaction of Genes and Hormones in Murine Hepatocarcinogenesis

N. Drinkwater, 1994 .

Molecular analysis of mutations induced in human cells by N‐ethyl‐N‐nitrosourea

K. Eckert, N. Drinkwater, C. A. Ingle, 1988, Molecular carcinogenesis.

Genetic and hormonal regulation of murine hepatocarcinogenesis.

N. Drinkwater, R. Carabeo, T. Chiaverotti, 1999, Progress in experimental tumor research.

Reduction to homozygosity is the predominant spontaneous mutational event in cultured human lymphoblastoid cells.

N. Drinkwater, D. Klinedinst, 1991, Mutation research.

The androgen receptor and liver tumor development in mice.

N. Drinkwater, C. Kemp, 1990, Progress in clinical and biological research.

Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.

A. Buchmann, M. Schwarz, N. Drinkwater, 1991, Proceedings of the National Academy of Sciences of the United States of America.

recA-dependent and recA-independent N-ethyl-N-nitrosourea mutagenesis at a plasmid-encoded herpes simplex virus thymidine kinase gene in Escherichia coli.

K. Eckert, N. Drinkwater, 1987, Mutation research.

Induction of three histochemically distinct populations of hepatic foci in C57BL/6J mice.

N. Drinkwater, M. L. Winkler, M. Hanigan, 1993, Carcinogenesis.

Genetic determinants of hepatocarcinogenesis in the B6C3F1 mouse.

N. Drinkwater, C. Kemp, M. Hanigan, 1989, Toxicology letters.

Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones.

N. Drinkwater, T. M. Poole, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The PPCD1 Mouse: Characterization of a Mouse Model for Posterior Polymorphous Corneal Dystrophy and Identification of a Candidate Gene

C. Murphy, R. Dubielzig, C. Kasper, 2010, PloS one.

Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression

L. Teixeira, N. Drinkwater, C. Bradfield, 2016, PloS one.

Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria.

E C Miller, H C Pitot, J A Miller, 1976, Journal of the National Cancer Institute.

Identification of hepatocarcinogen-resistance genes in DBA/2 mice.

G. -. Lee, N. Drinkwater, L. Bennett, 1995, Genetics.

Effect of Genetic Susceptibility on Tumor Induction

N. Drinkwater, 1995 .

Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens.

J. Miller, N. Drinkwater, E. Miller, 1980, Biochemistry.

Covalent intercalative binding to DNA in relation to the mutagenicity of hydrocarbon epoxides and N-acetoxy-2-acetylaminofluorene.

J. Miller, N. Drinkwater, E. Miller, 1978, Cancer research.

Genetic dissection of susceptibility to murine ovarian teratomas that originate from parthenogenetic oocytes.

K. Ogawa, G. -. Lee, H. Nishimori, 1997, Cancer research.

Quantitative analysis of the time-dependent development of glucose-6-phosphatase-deficient foci in the livers of mice treated neonatally with diethylnitrosamine.

J. Miller, H. Pitot, N. Drinkwater, 1981, Cancer research.

Covalent Intercalate Binding to DMA in Relation to the Mutagenicity of Hydrocarbon Epoxides and N-Acetoxy-2-acetylaminofluorene1

N. Drinkwater, E. Miller, J. Miller, 2006 .

Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells

N. Drinkwater, D. Klinedinst, 1992, Molecular carcinogenesis.

N-ethyl-N-nitrosourea induces A:T to C:G transversion mutations as well as transition mutations in SOS-induced Escherichia coli.

K. Eckert, N. Drinkwater, C. Ingle, 1989, Carcinogenesis.

Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice

N. Drinkwater, L. Schuler, C. Bradfield, 2014, Proceedings of the National Academy of Sciences.

DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase Status

M. Hanes, N. Drinkwater, R. Reddick, 2015, Cancer Prevention Research.

Conditional transformation of mouse liver epithelial cells. An in vitro model for analysis of genetic events in hepatocarcinogenesis.

K. Ogawa, G. -. Lee, N. Drinkwater, 1995, The American journal of pathology.

Genetic variation in liver tumor susceptibility, plasma testosterone levels, and androgen receptor binding in six inbred strains of mice.

N. Drinkwater, C. Kemp, Christopher J. Kemp, 1989, Cancer research.

Strain dependent effects of sex hormones on hepatocarcinogenesis in mice.

N. Drinkwater, T. M. Poole, 1996, Carcinogenesis.

Promotion of murine hepatocarcinogenesis by testosterone is androgen receptor-dependent but not cell autonomous.

N. Drinkwater, C. Kemp, C. Leary, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Chemically induced mutagenesis in a shuttle vector with a low-background mutant frequency.

N. Drinkwater, D. Klinedinst, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice.

N. Drinkwater, J. Ginsler, 1986, Carcinogenesis.

A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines.

H. Pitot, N. Drinkwater, L. Bennett, 2004, Genetics.

Strain‐dependent differences in DNA synthesis and gene expression in the regenerating livers of C57BL/6J and C3H/HeJ mice

P. Farnham, N. Drinkwater, L. Bennett, 1995, Molecular carcinogenesis.

Genetic susceptibility to liver cancer

N. Drinkwater, Lee Gang-Hong, Gang-Hong Lee, 1995 .

Genetic control of hepatocarcinogenesis in C3H mice.

N. Drinkwater, 1994, Drug metabolism reviews.

Rapid growth of preneoplastic lesions in hepatocarcinogen-sensitive C3H/HeJ male mice relative to C57BL/6J male mice.

N. Drinkwater, C. Kemp, M. Hanigan, 1988, Carcinogenesis.

Estrogen Receptor-α Suppresses Liver Carcinogenesis and Establishes Sex-Specific Gene Expression

H. Pitot, N. Drinkwater, P. Lambert, 2021, Cancers.

Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17

H. Pitot, N. Drinkwater, A. Bilger, 2009, Carcinogenesis.

Comparison of the frequency of diphtheria toxin and thioguanine resistance induced by a series of carcinogens to analyze their mutational specificities in diploid human fibroblasts.

N. Drinkwater, J. Mccormick, V. Maher, 1984, Mutation research.

An in situ assay for induced diphtheria-toxin-resistant mutants of diploid human fibroblasts.

N. Drinkwater, J. Mccormick, V. Maher, 1982, Mutation research.

Genetic and epigenetic promotion of murine hepatocarcinogenesis.

N. Drinkwater, C. Kemp, M. Hanigan, 1990, Progress in clinical and biological research.

Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.

N. Drinkwater, A. Prunuske, L. Clipson, 2008, Carcinogenesis.

Multiple genetic loci modify risk for retinoblastoma in transgenic mice.

N. Drinkwater, P. Lambert, D. Albert, 1998, Investigative ophthalmology & visual science.

Identification of susceptibility loci in a mouse model of KRASG12D-driven pancreatic cancer.

N. Drinkwater, B. R. Williams, E. Sandgren, 2010, Cancer research.

Genetic background determines if Stat5b suppresses or enhances murine hepatocarcinogenesis

N. Drinkwater, A. Bilger, Christopher C. Oberley, 2015, Molecular carcinogenesis.

Representational difference analysis of gene expression.

N. Drinkwater, J. Bugni, 2003, Methods in molecular biology.

Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models.

H. DeLuca, J. Amos-Landgraf, N. Drinkwater, 2011, Archives of biochemistry and biophysics.

Statistical methods for the analysis of tumor multiplicity data.

J. Klotz, N. Drinkwater, N R Drinkwater, 1981, Cancer research.

Biologic study of the effects of octreotide-LAR on growth hormone in unresectable and metastatic hepatocellular carcinoma.

J. Fine, N. Drinkwater, J. Eickhoff, 2008, Clinical advances in hematology & oncology : H&O.

C57BR/cdJ hepatocarcinogen susceptibility genes act cell-autonomously in C57BR/cdJ<-->C57BL/6J chimeras.

N. Drinkwater, T. Chiaverotti, 2003, Cancer research.

S-Driven Pancreatic Cancer

N. Drinkwater, B. R. Williams, A. Bilger, 2010 .

Cancer esearch cular and Cellular Pathobiology tification of Susceptibility Loci in a Mouse Model of R SG 12 D-Driven Pancreatic Cancer

N. Drinkwater, B. R. Williams, A. Bilger, 2010 .

The N-hydroxy metabolites of N-methyl-4-aminoazobenzene and related dyes as proximate carcinogens in the rat and mouse.

J. Miller, H. Pitot, N. Drinkwater, 1979, Cancer research.

Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors.

Gregory D Kennedy, Christopher A Bradfield, Stephen S Hecht, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

The Teratogenic Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Is Modified by a Locus on Mouse Chromosome 3

Emily A. Stevens, N. Drinkwater, C. Bradfield, 2006, Molecular Pharmacology.

Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor

Mark Craven, Christopher A Bradfield, M. Craven, 2004, PLoS biology.

Ancestral bias in the Hras1 gene and distal Chromosome 7 among inbred mice

Jennifer C. Drew, N. Drinkwater, A. S. Kastenmeier, 2007, Mammalian Genome.

Hepatocarcinogenesis in BXH recombinant inbred strains of mice: Analysis of diverse phenotypic effects of the hepatocarcinogen sensitivity loci

N. Drinkwater, Gang‐Hong Lee, Norman R. Drinkwater, 1995, Molecular carcinogenesis.

The Hcr (hepatocarcinogen resistance) loci of DBA/2J mice partially suppress phenotypic expression of the Hcs (hepatocarcinogen sensitivity) loci of C3H/HeJ mice.

N. Drinkwater, G. Lee, G. -. Lee, 1995, Carcinogenesis.

Partial hepatectomy is a promoter of hepatocarcinogenesis in C57BL/6J male mice but not in C3H/HeJ male mice.

N. Drinkwater, M. L. Winkler, M. Hanigan, 1990, Carcinogenesis.

Hormonal and genetic interactions in murine hepatocarcinogenesis.

N. Drinkwater, T. M. Poole, 1995, Progress in clinical and biological research.

Genetic control of carcinogenesis in experimental animals.

N. Drinkwater, L. Bennett, 1991, Progress in experimental tumor research.