Alasdair D. J. Freeman

发表

Single-molecule observation of the induction of k-turn RNA structure on binding L7Ae protein.

D. Lilley, Yanjun Liu, J. Ouellet, 2012, Biophysical journal.

Observing spontaneous branch migration of Holliday junctions one step at a time.

Taekjip Ha, D. Lilley, S. McKinney, 2005, Proceedings of the National Academy of Sciences of the United States of America.

University of Dundee A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme

D. Lilley, Yanjun Liu, A. Déclais, 2018 .

Human ANKLE1 Branched DNA

D. Lilley, A. Gartner, Alasdair D. J. Freeman, 2020 .

Biochemical and Structural Properties of Fungal Holliday Junction-Resolving Enzymes.

D. Lilley, A. Gartner, Yanjun Liu, 2018, Methods in enzymology.

The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions.

D. Lilley, A. Déclais, Alasdair D. J. Freeman, 2013, Journal of molecular biology.

Metal ion binding in the active site of the junction-resolving enzyme T7 endonuclease I in the presence and in the absence of DNA.

D. Lilley, A. Déclais, Alasdair D. J. Freeman, 2003, Journal of molecular biology.

The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

D. Lilley, A. Gartner, A. Déclais, 2010, PLoS genetics.

GEN1 from a Thermophilic Fungus Is Functionally Closely Similar to Non-Eukaryotic Junction-Resolving Enzymes

D. Lilley, A. Gartner, Yanjun Liu, 2014, Journal of molecular biology.

A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

D. Lilley, Yanjun Liu, A. Déclais, 2018, Nucleic acids research.

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

D. Lilley, A. Gartner, Yanjun Liu, 2015, Cell reports.

Human ANKLE1 Is a Nuclease Specific for Branched DNA

D. Lilley, A. Gartner, Alasdair D. J. Freeman, 2020, bioRxiv.

Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding

D. Lilley, D. Norman, A. Déclais, 2016, Biochemistry.

Analysis of conformational changes in the DNA junction-resolving enzyme T7 endonuclease I on binding a four-way junction using EPR.

D. Lilley, D. Norman, Alasdair D. J. Freeman, 2011, Biochemistry.

Structural recognition between a four-way DNA junction and a resolving enzyme.

D. Lilley, A. Déclais, Alasdair D. J. Freeman, 2006, Journal of molecular biology.

The complex between a four‐way DNA junction and T7 endonuclease I

D. Lilley, S. Phillips, A. Déclais, 2003, The EMBO journal.

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

D. Lilley, T. Ha, Ruobo Zhou, 2018, Nature Chemical Biology.

Biochemical and Structural Properties of Fungal Holliday Junction-Resolving Enzymes.

D. Lilley, A. Gartner, Yanjun Liu, 2018, Methods in enzymology.