B. Oberg

发表

Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism-Importance of slow dissociation and relaxation rates for antiviral efficacy.

L. Vrang, U. H. Danielson, Malin Elinder, 2010, Biochemical pharmacology.

Anti-HIV type 1 activity of 3'-fluoro-3'-deoxythymidine for several different multidrug-resistant mutants.

T. Merigan, L. Vrang, B. Oberg, 2001, AIDS research and human retroviruses.

Early appearance of simian immunodeficiency virus (SIV) antigen and antibodies as variables in evaluating antiviral drugs in macaques.

B. Oberg, B. Wahrén, E. Ljungdahl-Ståhle, 1992, Journal of virological methods.

In vitro translation with adenovirus polyribosomes

B. Oberg, L. Philipson, H. Persson, 1977, Journal of virology.

Replicative structures of poliovirus RNA in vivo.

L. Philipson, B. Oberg, 1971, Journal of molecular biology.

Efficacy of (-)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine in African green monkeys infected with simian varicella virus

B. Oberg, K. Soike, R. Bohm, 1993, Antimicrobial Agents and Chemotherapy.

Experimental infection of cynomolgus monkeys (Macaca fascicularis) with simian immunodeficiency virus (SIVsm).

J. Albert, B. Oberg, E. Norrby, 1989, Journal of acquired immune deficiency syndromes.

Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138-->Arg and Tyr-188-->His mutations.

L. Vrang, B. Oberg, T. Unge, 1994, Antiviral research.

Long-term tolerance and efficacy of 3'-azidothymidine and 3'-fluorothymidine treatment of asymptomatic monkeys infected with simian immunodeficiency virus

B. Oberg, L. Ståhle, S. Li, 1992, Antimicrobial Agents and Chemotherapy.

Inhibition of human immunodeficiency virus in vitro by combinations of 3'-azido-3'-deoxythymidine and foscarnet

L. Vrang, B. Oberg, B. Wahrén, 1989, Antimicrobial Agents and Chemotherapy.

An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs.

L. Vrang, J. Hansen, B. Oberg, 1989, Biochemical pharmacology.

Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

L. Vrang, B. Oberg, J. Morin, 1996, Journal of medicinal chemistry.

Purification and characterization of an early protein (E14K) from adenovirus type 2-infected cells

B. Oberg, L. Philipson, H. Persson, 1978, Journal of virology.

Partition studies on nucleic acids II. Countercurrent distribution of virus RNA

B. Oberg, L. Philipson, P. Albertsson, 1965 .

Carbethoxylation of polynucleotides.

B. Oberg, 1971, European journal of biochemistry.

Initiation of picornavirus protein synthesis in ascites cell extracts.

A. Shatkin, B. Oberg, 1972, Proceedings of the National Academy of Sciences of the United States of America.

In vivo and in vitro synthesis of adenovirus type 2 early proteins

B. Oberg, J. Saborio, 1976, Journal of virology.

Treatment of fulminant hepatitis B and fulminant hepatitis B and D coinfection with foscarnet.

O. Weiland, B. Oberg, B. Hansson, 1987, Progress in clinical and biological research.

Different patterns of inhibition of avian myeloblastosis virus reverse transcriptase activity by 3'-azido-3'-deoxythymidine 5'-triphosphate and its threo isomer

L. Vrang, B. Oberg, H. Bazin, 1987, Antimicrobial Agents and Chemotherapy.

Antiviral effects of phosphonoformate (PFA, foscarnet sodium).

B. Oberg, 1989, Pharmacology & therapeutics.

Intravenous foscarnet for the treatment of severe cytomegalovirus infection in allograft recipients.

G. Klintmalm, G. Gahrton, B. Oberg, 1985, Scandinavian journal of infectious diseases.

Identification of the in vitro translation products of adenovirus mRNA by immunoprecipitation

L. Philipson, B. Oberg, E. Everitt, 1975, Journal of virology.

Phosphonoformate inhibits reverse transcriptase.

B. Oberg, B. Sundquist, 1979, The Journal of general virology.

Antiherpetic activity and mechanism of action of 9-(4-hydroxybutyl)guanine.

B. Oberg, S. Alenius, A. Larsson, 1983, Antiviral research.

Antiherpes activity of [E]-5-(1-propenyl)-2'-deoxyuridine and 5-(1-propenyl)-1-beta-D-arabinofuranosyluracil.

B. Oberg, S. Alenius, A. Larsson, 1981, Antiviral research.

Mode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovir

B. Oberg, A. Ericson, A. Larsson, 1986, Antimicrobial Agents and Chemotherapy.

Inhibition of the reverse transcriptase from HIV by 3'-azido-3'-deoxythymidine triphosphate and its threo analogue.

L. Vrang, B. Oberg, H. Bazin, 1987, Antiviral research.

Kinetic analysis in cell culture of the reversal of antiherpes activity of nucleoside analogs by thymidine

B. Oberg, A. Larsson, G. Brännström, 1983, Antimicrobial Agents and Chemotherapy.

Reversible inhibition of cytomegalovirus replication by phosphonoformate.

B. Oberg, B. Wahrén, B. Öberg, 1980, Intervirology.

Trisodium phosphonoformate, a new antiviral compound.

B. Oberg, A. Larsson, B. Eriksson, 1978, Science.

Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin.

B. Oberg, B. Wahrén, B. Öberg, 1982, Biochimica et biophysica acta.

Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase.

B. Oberg, A. Larsson, B. Öberg, 1980, Biochimica et biophysica acta.

9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication

B. Oberg, S. Alenius, A. Larsson, 1983, Antimicrobial Agents and Chemotherapy.

No in vivo effect of trisodium phosphonoformate on woodchuck hepatitis virus production.

A. Widell, B. Oberg, B. Hansson, 2009, Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology.

Inhibition of HIV-1 reverse transcriptase by 5'-triphosphates of 5-substituted uridine analogs.

B. Oberg, R. Datema, N. Johansson, 1989, Antiviral research.

Antiherpes effects and pharmacokinetic properties of 9-(4-hydroxybutyl) guanine and the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine

F. Aoki, B. Oberg, A. Ericson, 1985, Antimicrobial Agents and Chemotherapy.

Influence of cells and virus multiplicity on the inhibition of herpesviruses with acycloguanosine.

B. Oberg, B. Wahrén, J. Harmenberg, 1980, Intervirology.

Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs.

B. Oberg, S. Eriksson, B. Öberg, 1991, Biochemical and biophysical research communications.

Achievements and Challenges in Antiviral Drug Discovery

B. Oberg, E. Littler, 2005, Antiviral chemistry & chemotherapy.

Antiviral effects of 3'-fluorothymidine and 3'-azidothymidine in cynomolgus monkeys infected with simian immunodeficiency virus.

B. Oberg, E. Norrby, B. Wahrén, 1991, Journal of acquired immune deficiency syndromes.

Inhibition of RNA- and DNA-dependent duck hepatitis B virus DNA polymerase activity by nucleoside and pyrophosphate analogs.

B. Oberg, E. Nordenfelt, B. Löfgren, 1989, Antiviral research.

in African GreenMonkeysInfected WithSimian Varicella Virus

B. Oberg, R. Bohm, 1993 .

Pharmacokinetics and distribution over the blood brain barrier of two acyclic guanosine analogs in rats, studied by microdialysis

B. Oberg, L. Ståhle, 1992, Antimicrobial Agents and Chemotherapy.

Therapeutic effects of foscarnet sodium and acyclovir on cutaneous infections due to herpes simplex virus type 1 in guinea pigs.

B. Oberg, S. Alenius, K. Eklind, 1982, The Journal of infectious diseases.

Prevention of ulcerative lesions by episodic treatment of recurrent herpes labialis: A literature review.

B. Oberg, J. Harmenberg, S. Spruance, 2010, Acta Dermato-Venereologica.

ModeofAction, Toxicity, Pharmacokinetics, andEfficacy ofSome NewAntiherpesvirus Guanosine Analogs Related toBuciclovir

B. Oberg, W. Yisak, U. Haglund, 1986 .

The relative merits and drawbacks of new nucleoside analogues with clinical potential.

B. Oberg, N. Johansson, 1984, Journal of Antimicrobial Chemotherapy.

Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleo

L. Vrang, A. Vandamme, B. Oberg, 1993, Proceedings of the National Academy of Sciences of the United States of America.

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase.

E. De Clercq, L. Vrang, A. Vandamme, 1993, Virology.

Inhibition of HTLV-III/LAV replication by foscarnet.

B. Oberg, D. Sun, P. Sarin, 1985, Biochemical pharmacology.

PPi analogs as inhibitors of human T-lymphotropic virus type III reverse transcriptase

L. Vrang, B. Oberg, 1986, Antimicrobial Agents and Chemotherapy.

Influence of twenty potentially antiviral substances on in vitro multiplication of hepatitis A virus.

A. Widell, B. Oberg, B. Hansson, 1986, Antiviral research.

Activity of the cytomegalovirus genome in the presence of PPi analogs

B. Oberg, B. Wahrén, B. Eriksson, 1985, Journal of virology.

Inhibition of reverse transcriptase activity of avian myeloblastosis virus by pyrophosphate analogues.

B. Oberg, B. Eriksson, G. Stening, 1982, Antiviral research.

Inhibition of cytomegalovirus late antigens by phosphonoformate.

B. Oberg, B. Wahrén, B. Wahren, 1979, Intervirology.

Reverse transcriptases from human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIVMAC) are susceptible to inhibition by foscarnet and 3'-azido-3'-deoxythymidine triphosphate

L. Vrang, R. Kurth, J. Löwer, 1988, Antimicrobial Agents and Chemotherapy.

Binding of histidine to tobacco mosaic virus RNA.

L. Philipson, B. Oberg, 1972, Biochemical and biophysical research communications.

Precipitation of nucleotides by calcium phosphate.

B. Oberg, J. Chattopadhyaya, K. Stenberg, 1982, Biochimica et biophysica acta.

The cordycepin analogue of 2,5A and its threo isomer. Chemical synthesis, conformation and biological activity.

L. Vrang, A. Drake, B. Oberg, 1986, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry.

The HIV replication inhibitor 3'-fluoro-3'-deoxythymidine blocks sialylation of N-linked oligosaccharides.

B. Oberg, S. Eriksson, A. Karlsson, 1992, Antiviral research.

Functional analysis of influenza RNA polymerase activity by the use of caps, oligonucleotides and polynucleotides.

B. Oberg, J. Chattopadhyaya, S. Josephson, 1981, Antiviral research.

Enzymatic targets in virus chemotherapy.

B. Oberg, E. Helgstrand, 1980, Antibiotics and chemotherapy.

Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127.

L. Vrang, B. Oberg, T. Unge, 1995, Antiviral research.

Prevention of HIV-2 and SIV infections in cynomolgus macaques by prophylactic treatment with 3'-fluorothymidine.

B. Oberg, B. Öberg, P. Putkonen, 1992, AIDS research and human retroviruses.

Effect of aphidicolin on DNA synthesis in HSV-1 infected and uninfected Vero cells.

B. Oberg, A. Larsson, M. Wrååk, 1983, Antiviral research.

The chemical synthesis and antiviral properties of an acyclovir-phospholipid conjugate.

C. Welch, B. Oberg, A. Ericson, 1985, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry.

Penetration of zidovudine and 3'-fluoro-3'-deoxythymidine into the brain, muscle tissue, and veins in cynomolgus monkeys: relation to antiviral action

B. Oberg, B. Wahrén, L. Ståhle, 1992, Antimicrobial Agents and Chemotherapy.

Purification of adenovirus messenger ribonucleic acid by an aqueous polymer two-phase system.

L. Philipson, B. Oberg, K. Johansson, 1976, Biochemistry.

Translation of mengovirus RNA in Ehrlich ascites cell extracts.

A. Shatkin, B. Oberg, 1974, Biochemical and biophysical research communications.

Replication of poliovirus RNA studied by gel filtration and electrophoresis.

L. Philipson, B. Oberg, 1969, European journal of biochemistry.

An in vivo model for HIV resistance development.

J. Heeney, B. Oberg, B. Zuber, 2001, AIDS research and human retroviruses.

Gel filtration of nucleic acids on sphere-condensed agarose.

L. Philipson, B. Oberg, 1967, Archives of biochemistry and biophysics.

Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors.

Wesley Schaal, Anders Karlén, Magnus Björsne, 2003, European journal of biochemistry.

Enhancement of HIV-1 proteinase activity by HIV-1 reverse transcriptase.

B. Strandberg, B. Oberg, T. Unge, 1995, Virology.

Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors.

W. Haseltine, B. Oberg, K. Uberla, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues.

L. Vrang, B. Oberg, T. Unge, 1999, Journal of medicinal chemistry.

GEL FILTRATION OF NUCLEIC ACIDS ON PEARL-CONDENSED AGAROSE.

B. Oberg, L. Philipson, S. Bengtsson, 1965, Biochemical and biophysical research communications.

Biochemical and biological characteristics of carbethoxylated poliovirus and viral RNA.

B. Oberg, 1970, Biochimica et biophysica acta.

immunoprecipitation. adenovirus mRNA by translation products of Identification of the in vitro

L. Philipson, B. Oberg, E. Everitt, 2013 .

High-yield purification of HIV-1 proteinase expressed by a synthetic gene in Escherichia coli.

T. Grundström, B. Oberg, E. Norrby, 1991, Protein expression and purification.

Simian immunodeficiency virus (SIVsm) isolation from blood and brain of experimentally infected macaques.

F. Chiodi, E. Fenyö, B. Oberg, 1991, AIDS.

Adjunctive corticosteroid therapy in bacterial meningitis.

B. Oberg, A. Lauritsen, 1995, Scandinavian journal of infectious diseases.

Antiviral therapy.

B. Oberg, 1988, Journal of acquired immune deficiency syndromes.

RNA ligase activity in phage-infected bacteria and animal cells.

L. Philipson, B. Oberg, T. Linné, 1974, European Journal of Biochemistry.